Expression of estrogen receptors in a normal human breast epithelial cell type with luminal and stem cell characteristics and its neoplastically transformed cell lines

Carcinogenesis

Volumn 18, Issue 2, 1997, Pages 251-257

  Kang, Kyung Sun ^a   Morita, Ikue ^a   Cruz, Angela ^a   Jeon, Young Jin ^a   Trosko, James E ^a   Chang, Chia Cheng ^a  

^a MICHIGAN STATE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ESTROGEN RECEPTOR; MESSENGER RNA;

ADULT; AMINO TERMINAL SEQUENCE; ARTICLE; BINDING SITE; BREAST CANCER; BREAST EPITHELIUM; BREAST REDUCTION; CARBOXY TERMINAL SEQUENCE; CASE REPORT; CELL CULTURE; CELL TRANSFORMATION; CELL TYPE; CONTROLLED STUDY; ELECTROPHORETIC MOBILITY; EPITHELIUM CELL; FEMALE; GENE DELETION; HUMAN; HUMAN CELL; IMMUNOBLOTTING; IMMUNOFLUORESCENCE; MAMMARY GLAND; PRIORITY JOURNAL; PROTEIN DNA BINDING; PROTEIN EXPRESSION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RNA SPLICING; SIMIAN VIRUS 40; STEM CELL;

ADULT; ANIMALS; BLOTTING, WESTERN; BREAST; BREAST NEOPLASMS; CELL CYCLE PROTEINS; CELL LINE, TRANSFORMED; DNA; EPITHELIUM; FEMALE; HUMANS; MICE; MICE, NUDE; POLYMERASE CHAIN REACTION; RECEPTORS, ESTROGEN; SIMIAN VIRUS 40; TUMOR CELLS, CULTURED; TUMOR STEM CELLS;

EID: 0031426391     PISSN: 01433334     EISSN: None     Source Type: Journal    
DOI: 10.1093/carcin/18.2.251     Document Type: Article

References (46)

1. Gronemeyer, H. (1991) Transcription activation by estrogen and progesterone receptors. Ann. Rev. Genetics, 25, 89-123.
2. Dickson, R.B. and Lippman, M.E. (1994) Molecular basis of breast cancer. In Mendelsohn, J., Howley, P.M., Israel, M.A. and Liotta, L.A. (eds), The Molecular Basis of Cancer. W.B. Saunders Co., Philadelphia, pp. 358-384.
3. Lippman, M.E. and Allegra, J.C. (1980) Quantitative estrogen receptor analysis: The response to endocrine and cytotoxic chemotherapy in human breast cancer and the disease-free interval. Cancer, 46, 2829-2834.
4. Manni, A., Arafah, B. and Pearson, O.H. (1980) Estrogen and progesterone receptors in the prediction of response of breast cancer to endocrine therapy. Cancer, 46, 2838-2841.
5. Iglehart, D. (1991) The breast. In Sabiston, P.C. (ed.), Textbook of Surgery. W.B. Saunders, Philadelphia, 4th edition, pp. 510-550.
6. Ricketts, D., Turnbull, L., Ryall, G., Bakshi, R., Rawson, N.S.B., Gazet, J.C., Nolan, C. and Coombes, R.C. (1991) Estrogen and progesterone receptors in the normal female breast. Cancer Res., 51, 1817-1822.
7. Pike, M.C. Krailo, M.D., Henderson, B.E., Casagrande, J.T. and Hoel, D.G. (1983) 'Hormonal' risk factors, 'breast tissue age' and the age-incidence of breast cancer. Nature, 303, 767-770.
8. Henderson, B.E., Ross, R.K., Judd, H.L., Krailo, M.D. and Pike, M.C. (1985) Do regular ovulatory cycles increase breast cancer risk? Cancer, 56, 1206-1208.
9. Davis. D.L., Bradlow, H.L., Wolff, M., Woodruff, T., Hoel, D.G. and Anton-Culver, H. (1993) Medical hypothesis: Xenoestrogens as preventable causes of breast cancer. Environ. Hlth Perspect., 101, 372-377.
10. Walter, P., Green, S., Greene, G., Krust, A., Bornert, J.-M., Jeltsch, J.-M Staub, A., Jensen, E., Scrace, G., Waterfield, M. and Chambon, P. (1985) Cloning of the human estrogen receptor cDNA. Proc. Natl Acad. Sci. USA, 82, 7889-7893.
11. Ponglikitmongkol, M., Green, S. and Chambon, P. (1988) Genomic organization of the human oestrogen receptor gene. EMBO J., 7, 3383-1388.
12. Kumar, V., Green, S., Stack, G., Berry, M., Jin, J.R. and Chambon, P. (1987) Functional domains of the human estrogen receptor. Cell, 51, 941-951.
13. Tora, L., White, J., Brou, C., Tasset, D., Webster, N., Scheer, E. and Chambon, P. (1989) The human estrogen receptor has two independent transcriptional activation functions. Cell, 59, 477-478.
14. Danielian, P.S., White, R., Lees, J.A. and Parker, M.G. (1992) Identification of a conserved region required for hormone dependent transcriptional activation by steroid hormone receptors. EMBO J., 11, 1025-1033.
15. Roodi, N., Bailey, L.R., Kao, W.-Y., Verrier, C.S., Yee, C.J., Dupont, W.D. and Parl, F.F. (1995) Estrogen receptor gene analysis in estrogen receptor-positive and receptor-negative primary breast cancer. J. Natl Cancer Inst., 87, 446-451.
16. Lees, J.A., Fawell, S.E., White, R. and Parker, M.G. (1990) A 22-amino acid peptide restores DNA binding activity to dimerization defective mutants of the estrogen receptor. Mol. Cell. Biol., 10, 5529-5533.
17. Pfeffer, U., Fecarotta, E., Castagnetta, L. and Vidali, G. (1993) Estrogen receptor variant messenger RNA lacking exon 4 in estrogen-responsive human breast cancer cell lines. Cancer Res., 53, 741-743.
18. Zhang, Q.-X., Borg, A. and Fuqua, S.A.W. (1993) An exon 5 deletion variant of the estrogen receptor frequently coexpressed with wild-type estrogen receptor in human breast cancer. Cancer Res., 53, 5882-5884.
19. Castles, C.G., Fuqua, S.A.W., Klotz, D.M. and Hill, S.M. (1993) Expression of a constitutively active estrogen receptor variant in the estrogen receptor-negative BT-20 human breast cancer cell line. Cancer Res., 53, 5934-5939.
20. Miksicek, R.J. (1994) Steroid receptor variants and their potential role in cancer. Cancer Biology, 5, 369-379.
21. Pfeffer, U., Fecarotta, E. and Vidali, G. (1995) Coexpression of multiple estrogen receptor variant messenger RNAs in normal and neoplastic breast tissues and in MCF-7 cells. Cancer Res., 55, 2158-2165.
22. Fuqua, S.A.W. and Wolf, D.M. (1995) Molecular aspects of estrogen receptor variants in breast cancer. Breast Cancer Res. Treat., 35, 233-241.
23. Rea, D. and Parker, M.G. (1996) Effects of an exon 5 variant of the estrogen receptor in MCF-7 breast cancer cells. Cancer Res., 56, 1556-1563.
24. Fuqua, S.A.W., Fitzgerald, S.D., Chamness, G.C., Tandon, A.K., McDonnell, D.P., Nawaz, Z., O'Malley, B.W. and McGuire, W.L. (1991) Variant human breast tumor estrogen receptor with constitutive transcriptional activity. Cancer Res., 51, 105-109.
25. Daffada, A.A.I., Johnston, S.R.D., Smith, I.E., Detre, S., King, N. and Dowsett, M. (1995) Exon 5 deletion variant estrogen receptor messenger RNA expression in relation to tamoxifen resistance and progesterone receptor/pS2 status in human breast cancer. Cancer Res., 55, 288-293.
26. Petersen, O.W., Høyer, P.E. and van Deurs, B. (1987) Frequency and distribution of estrogen receptor-positive cells in normal, nonlactating human breast tissue. Cancer Res., 47, 5748-5751.
27. Hammond, S.L., Ham, R.G. and Stampfer, M.R. (1984) Serum-free growth of human mammary epithelial cells: Rapid clonal growth in defined medium and extended serial passage with pituitary extract. Proc. Natl Acad. Sci. USA, 81, 5435-5439.
28. Band, V. and Sager, R. (1989) Distinctive traits of normal and tumor-derived human mammary epithelial cells expressed in a medium that supports long-term growth of both cell types. Proc. Natl Acad. Sci. USA, 86, 1249-1253.
29. Kao, C.-Y., Nomata, K., Oakley, C.S., Welsch, C.W. and Chang, C.-C. (1995) Two types of normal human breast epithelial cells derived from reduction mammoplasty: phenotypic characterization and response to SV40 transfection. Carcinogenesis, 16, 531-538.
30. Chang, C.-C., Liu, C.J., Deocampo, N., Kang, K.-S. and Trosko, J.E. (1996) The unique ability of a normal human breast epithelial cell type with stem cell and luminal epithelial cell characteristics to form budding and ductal structures in Matrigel matrix. Proc. Am. Assoc. Cancer Res., 37, 38.
31. Kang, K.-S., Wilson, M.R., Hayashi, T., Chang, C.-C. and Trosko, J.E. (1996) Inhibition of gap junctional intercellular communication in normal human breast epithelial cells after treatment with pesticides, PCBs, and PBBs, alone or in mixtures. Environ. Hlth Perspect., 104, 192-200.
32. Nomato, K., Kang, K.-S., Hayashi, T., Matesic, D., Lockwood, B., Chang, C.-C. and Trosko, J.E. (1996) Inhibition of gap junctional intercellular communication in heptachlor- and heptachlor-epoxide-treated normal human breast epithelial cells. Cell Biol. Toxicol., 12, 69-78.
33. Ferguson, A.T., Lapidus, R.G., Baylin, S.B. and Davidson, N.E. (1995) Demethylation of the estrogen receptor gene in estrogen receptor-negative breast cancer cells can reactivate estrogen receptor gene expression. Cancer Res., 55, 2279-2283.
34. Weigel, R.J., Crooks, D.L., Iglehart, D. and deConinck, E.C. (1995) Quantitative analysis of the transcriptional start sites of estrogen receptor in breast carcinoma. Cell Growth Different., 6, 707-711.
35. Liu, H., Wormkem, M., Safe, S.H. and Bjeldanes, L.F. (1994) Indole[3,2-b]carbazole: a dietary-derived factor that exhibits both antiestrogenic and estrogenic activity. J. Natl Cancer Inst., 86, 1758-1765.
36. Johnston, S.R.D., Saccani-Jotti, G., Smith, I.E., Salter, J., Newby, J., Coppen, M., Ebbs, S.R. and Dowsett, M. (1995) Changes in estrogen receptor, progesteron receptor, and pS2 expression in Tamoxifen-resistant human breast cancer. Cancer Res., 55, 3331-3338.
37. Leygue, E.R., Watson, P.H. and Murphy, L.C. (1996) Estrogen receptor variants in normal human mammary tissue. J. Natl Cancer Inst., 88, 284-296.
38. Wang, Y. and Miksicek, R.J. (1991) Identification of a dominant negative form of the human estrogen receptor. Mol. Endocrinol., 5, 1707-1715.
39. Fuqua, S.A.W., Fitzgerald, S.D., Allred, D.C, Elledge, R.M., Nawaz, Z., McDonnel, D.R, O'Malley, B.W., Greene, G.L. and McGuire, W.L. (1992) Inhibition of estrogen receptor action by a naturally occurring variant in human breast tumors. Cancer Res., 52, 483-486.
40. Pfeffer, U., Fecarotta, E., Castagnetta, L. and Vidali, G. (1993) Estrogen receptor variant messenger RNA lacking exon 4 in estrogen-responsive human breast cancer cell lines. Cancer Res., 53, 741-743.
41. Fuqua, S.A.W., Allred, D.C., Elledge, R.M., Elledge, R.M., Krieg, S.L., Benedix, M.G., Nawaz, Z., O'Malley, B.W., Greene, G.L. and McGuire, W.L. (1993) The ER-positive/PR-negative breast cancer phenotype is not associated with mutations within the DNA binding domains. Breast Cancer Res. Treat., 26, 191-202.
42. Miksicek, R.J., Lei, Y. and Wang, Y. (1993) Exon skipping gives rise to alternatively spliced forms of the estrogen receptor in breast tumour cells. Breast Cancer Res. Treat., 26, 163-174.
43. Ray, A., Prefontaine, K.E. and Ray, P. (1994) Down-modulation of interleukin-6 gene expression by 17β-estradiol in the absence of high affinity DNA binding by the estrogen receptor. JBC, 269, 12940-12946.
44. Seol, W., Choi, H.-S. and Moore, D.D. (1996) An orphan nuclear hormone receptor that lacks a DNA binding domain and heterodimerizes with other receptors. Science, 272, 1336-1339.
45. Yang, N.N., Venugopalan, M., Hardikar, S. and Glasebrook, A. (1996) Identification of an estrogen response element activated by metabolites of 17β-estradiol and raloxifene. Science, 273, 1222-1225.
46. Potter, V.R. (1978) Phenotypic diversity in experimental hepatomas: The concept of partially blocked ontogeny. Br. J. Cancer, 38, 1-23.