A novel N-alkylated prodigiosin analogue induced death in tumour cell through apoptosis or necrosis depending upon the cell type

Cancer Chemotherapy and Pharmacology

Volumn 61, Issue 3, 2008, Pages 355-363

  Deorukhkar, Amit A ^a   Chander, Ramesh ^a   Pandey, Ruchi ^a   Sainis, Krishna B ^a  

^a BHABHA ATOMIC RESEARCH CENTRE   (India)

Author keywords

Apoptosis; Necrosis; Prodigiosin; S 180

Indexed keywords

2,2' [3 METHOXY 1'AMYL 5' METHYL 4 (1'' PYRRYL)] DIPYRRYL METHENE; 3 (4,5 DIMETHYLTHIAZOLE 2 YL) 2,5 DIPHENYL TETRAZOLIUM BROMIDE; CASPASE 3; DNA; DNA FRAGMENT; PRODIGIOSIN; PROPIDIUM IODIDE; UNCLASSIFIED DRUG;

ANIMAL CELL; APOPTOSIS; ARTICLE; CELL DEATH; CELL LINE; CELL PROLIFERATION; CELL TYPE; CELL VIABILITY; CONTROLLED STUDY; DNA CONTENT; ENZYME ACTIVATION; ENZYME ACTIVITY; FIBROSARCOMA; FLOW CYTOMETRY; MOUSE; NECROSIS; NONHUMAN; PRIORITY JOURNAL; TUMOR CELL;

ALKENES; ALKYLATION; ANIMALS; ANTINEOPLASTIC AGENTS; APOPTOSIS; CELL LINE, TUMOR; CELL MEMBRANE PERMEABILITY; CELL SURVIVAL; DACTINOMYCIN; DIPLOIDY; DNA FRAGMENTATION; DNA, NEOPLASM; ENZYME INHIBITORS; LYMPHOMA, T-CELL; MICE; NECROSIS; PRODIGIOSIN; PYRROLES; RATS; SARCOMA 180; STAUROSPORINE; TETRAZOLIUM SALTS; THIAZOLES;

EID: 37249057908     PISSN: 03445704     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00280-007-0475-y     Document Type: Article

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