Non-apoptotic concentrations of prodigiosin (H+/Cl- symporter) inhibit the acidification of lysosomes and induce cell cycle blockage in colon cancer cells

Life Sciences

Volumn 78, Issue 2, 2005, Pages 121-127

  Castillo Ávila, Wilmar ^a   Abal, Miguel ^b   Robine, Sylvie ^b   Pérez Tomás, Ricardo ^a  

^a CCBR Group   (Spain)

^b INSTITUT CURIE   (France)

Author keywords

Cell cycle; Lysosome; p53; pH; Prodigiosin

Indexed keywords

ACRIDINE ORANGE; COTRANSPORTER; CYCLIN DEPENDENT KINASE INHIBITOR 1; PRODIGIOSIN; PROTEIN P53;

ACIDIFICATION; ALKALINIZATION; APOPTOSIS; ARTICLE; CANCER CELL; CELL CYCLE; CELL CYCLE G1 PHASE; CELL PH; CELL STRAIN HT29; COLON CANCER; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; CORRELATION ANALYSIS; CYTOSOL; CYTOTOXICITY; HUMAN; HUMAN CELL; LYSOSOME; PROTEIN INDUCTION; VITAL STAIN;

ADENOCARCINOMA; ANTINEOPLASTIC AGENTS; ANTIPORTERS; BLOTTING, WESTERN; CELL CYCLE; CELL LINE, TUMOR; COLONIC NEOPLASMS; G1 PHASE; GENES, P53; HUMANS; HYDROGEN-ION CONCENTRATION; LYSOSOMES; MICROSCOPY, FLUORESCENCE; PRODIGIOSIN;

BACTERIA (MICROORGANISMS);

EID: 27644474427     PISSN: 00243205     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.lfs.2005.04.059     Document Type: Article

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