-
1
-
-
0027925829
-
Autosomal dominant polycystic kidney disease
-
Gabow P. Autosomal dominant polycystic kidney disease. N Eng J Med 1993; 329: 332-342.
-
(1993)
N Eng J Med
, vol.329
, pp. 332-342
-
-
Gabow, P.1
-
2
-
-
0028278058
-
The polycystic kidney disease 1 gene encodes a 14 kb transcript and lies within a duplicated region on chromosome 16
-
The European Polycystic Kidney Disease Consortium
-
The European Polycystic Kidney Disease Consortium. The polycystic kidney disease 1 gene encodes a 14 kb transcript and lies within a duplicated region on chromosome 16. Cell 1994; 77: 881-894.
-
(1994)
Cell
, vol.77
, pp. 881-894
-
-
-
3
-
-
0028942745
-
Analysis of the genomic sequence for the autosomal dominant polycystic kidney disease (PKD1) gene predicts the presence of a leucine-rich repeat
-
The American PKD1 Consortium
-
The American PKD1 Consortium. Analysis of the genomic sequence for the autosomal dominant polycystic kidney disease (PKD1) gene predicts the presence of a leucine-rich repeat. Hum Mol Genet 1995; 4: 575-582.
-
(1995)
Hum Mol Genet
, vol.4
, pp. 575-582
-
-
-
4
-
-
0029002967
-
Polycystic kidney disease: The complete structure of the PKD1 gene and its protein
-
The International Polycystic Kidney Disease Consortium
-
The International Polycystic Kidney Disease Consortium. Polycystic kidney disease: the complete structure of the PKD1 gene and its protein. Cell 1995; 8: 289-298.
-
(1995)
Cell
, vol.8
, pp. 289-298
-
-
-
5
-
-
15844385078
-
PKD2, a gene for polycystic kidney disease that encodes an integral membrane protein
-
Mochizuki T, Wu G, Hayashi T et al. PKD2, a gene for polycystic kidney disease that encodes an integral membrane protein. Science 1996; 272: 1339-1342.
-
(1996)
Science
, vol.272
, pp. 1339-1342
-
-
Mochizuki, T.1
Wu, G.2
Hayashi, T.3
-
6
-
-
18344366124
-
PKHD1, the polycystic kidney and hepatic disease 1 gene, encodes a novel large protein containing multiple IPT domains and PbH1 repeats
-
Onuchic L, Furu L, Nagasawa Y et al. PKHD1, the polycystic kidney and hepatic disease 1 gene, encodes a novel large protein containing multiple IPT domains and PbH1 repeats. Am J Hum Genet 2002; 70: 1305-1317.
-
(2002)
Am J Hum Genet
, vol.70
, pp. 1305-1317
-
-
Onuchic, L.1
Furu, L.2
Nagasawa, Y.3
-
7
-
-
0036509712
-
The gene mutated in autosomal recessive polycystic kidney disease encodes a large, receptor-like protein
-
Ward C, Hogan M, Rossetti S et al. The gene mutated in autosomal recessive polycystic kidney disease encodes a large, receptor-like protein. Nat Genet 2002; 30: 259-269.
-
(2002)
Nat Genet
, vol.30
, pp. 259-269
-
-
Ward, C.1
Hogan, M.2
Rossetti, S.3
-
8
-
-
0036785149
-
The polycystic kidney disease proteins, polycystin-1, polycystin-2, polaris, and cystin, are co-localized in renal cilia
-
Yoder BK, Hou X, Guay-Woodford LM. The polycystic kidney disease proteins, polycystin-1, polycystin-2, polaris, and cystin, are co-localized in renal cilia. J Am Soc Nephrol 2002; 13: 2508-2516.
-
(2002)
J Am Soc Nephrol
, vol.13
, pp. 2508-2516
-
-
Yoder, B.K.1
Hou, X.2
Guay-Woodford, L.M.3
-
9
-
-
0037884961
-
Kidney-specific inactivation of the KIF3A subunit of kinesin-II inhibits renal ciliogenesis and produces polycystic kidney disease
-
Lin F, Hiesberger T, Cordes K et al. Kidney-specific inactivation of the KIF3A subunit of kinesin-II inhibits renal ciliogenesis and produces polycystic kidney disease. Proc Natl Acad Sci USA 2003; 100: 5286-5291.
-
(2003)
Proc Natl Acad Sci USA
, vol.100
, pp. 5286-5291
-
-
Lin, F.1
Hiesberger, T.2
Cordes, K.3
-
10
-
-
0037115494
-
Expression analyses and interaction with the anaphase promoting complex protein Apc2 suggest a role for inversin in primary cilia and involvement in the cell cycle
-
Morgan D, Eley L, Sayer J et al. Expression analyses and interaction with the anaphase promoting complex protein Apc2 suggest a role for inversin in primary cilia and involvement in the cell cycle. Hum Mol Gen 2002; 11: 3345-3350.
-
(2002)
Hum Mol Gen
, vol.11
, pp. 3345-3350
-
-
Morgan, D.1
Eley, L.2
Sayer, J.3
-
11
-
-
0035159015
-
-
Taulman P, Haycraft C, Balkovetz D, Yoder B. Polaris, a protein involved in left-right axis patterning, localizes to basal bodies and cilia. Mol Biol Cell 2001; 12: 589-599.
-
Taulman P, Haycraft C, Balkovetz D, Yoder B. Polaris, a protein involved in left-right axis patterning, localizes to basal bodies and cilia. Mol Biol Cell 2001; 12: 589-599.
-
-
-
-
12
-
-
0037377655
-
Delayed cystogenesis and increased ciliogenesis associated with the re-expression of polaris in Tg737 mutant mice
-
Brown N, Murcia N. Delayed cystogenesis and increased ciliogenesis associated with the re-expression of polaris in Tg737 mutant mice. Kidney Int 2003; 63: 1220-1229.
-
(2003)
Kidney Int
, vol.63
, pp. 1220-1229
-
-
Brown, N.1
Murcia, N.2
-
13
-
-
0036177603
-
Cystin, a novel cilia-associated protein, is disrupted in the cpk mouse model of polycystic kidney disease
-
Hou X, Mrug M, Yoder B et al. Cystin, a novel cilia-associated protein, is disrupted in the cpk mouse model of polycystic kidney disease. J Clin Invest 2002; 109: 533-540.
-
(2002)
J Clin Invest
, vol.109
, pp. 533-540
-
-
Hou, X.1
Mrug, M.2
Yoder, B.3
-
14
-
-
0028227826
-
Taxol inhibits progression of congenital polycystic kidney disease
-
Woo D, Miao S, Pelayo J, Woolf A. Taxol inhibits progression of congenital polycystic kidney disease. Nature 1994; 368: 750-753.
-
(1994)
Nature
, vol.368
, pp. 750-753
-
-
Woo, D.1
Miao, S.2
Pelayo, J.3
Woolf, A.4
-
15
-
-
0035498717
-
Bending the MDCK cell primary cilium increases intracellular calcium
-
Praetorius H, Spring K. Bending the MDCK cell primary cilium increases intracellular calcium. J Membr Biol 2001; 184: 71-79.
-
(2001)
J Membr Biol
, vol.184
, pp. 71-79
-
-
Praetorius, H.1
Spring, K.2
-
16
-
-
37249019294
-
Removal of the MDCK cell primary cilium abolished flow sensing
-
Praetorius H, Spring K. Removal of the MDCK cell primary cilium abolished flow sensing. J Membr Biol 2003; 10: 1-9.
-
(2003)
J Membr Biol
, vol.10
, pp. 1-9
-
-
Praetorius, H.1
Spring, K.2
-
17
-
-
0036122434
-
Polycystin-2 is an intracellular calcium release channel
-
Koulen P, Cai Y, Geng L et al. Polycystin-2 is an intracellular calcium release channel. Nat Cell Biol 2002; 4: 191-197.
-
(2002)
Nat Cell Biol
, vol.4
, pp. 191-197
-
-
Koulen, P.1
Cai, Y.2
Geng, L.3
-
18
-
-
31144441728
-
Molecular pathogenesis of autosomal dominant polycystic kidney disease
-
Yoder BK, Mulroy S, Eustace H et al. Molecular pathogenesis of autosomal dominant polycystic kidney disease. Expert Rev Mol Med 2006; 8: 1-22.
-
(2006)
Expert Rev Mol Med
, vol.8
, pp. 1-22
-
-
Yoder, B.K.1
Mulroy, S.2
Eustace, H.3
-
19
-
-
0034652247
-
Polycystin 1 is required for the structural integrity of blood vessels
-
Kim K, Drummond I, Ibraghimov-Beskrovnaya O et al. Polycystin 1 is required for the structural integrity of blood vessels. Proc Natl Acad Sci USA 2000; 97: 1731-1736.
-
(2000)
Proc Natl Acad Sci USA
, vol.97
, pp. 1731-1736
-
-
Kim, K.1
Drummond, I.2
Ibraghimov-Beskrovnaya, O.3
-
20
-
-
16644384500
-
The gene expression profile of cyst epithelial cells in autosomal dominant polycystic kidney disease patients
-
Lee JE, Park MH, Park JH. The gene expression profile of cyst epithelial cells in autosomal dominant polycystic kidney disease patients. J Biochem Mol Biol 2004; 37: 612-617.
-
(2004)
J Biochem Mol Biol
, vol.37
, pp. 612-617
-
-
Lee, J.E.1
Park, M.H.2
Park, J.H.3
-
21
-
-
3843051389
-
New insights into ADPKD molecular pathways using combination of SAGE and microarray technologies
-
Husson H, Manavalan P, Akmaev VR et al. New insights into ADPKD molecular pathways using combination of SAGE and microarray technologies. Genomics 2004; 84: 497-510.
-
(2004)
Genomics
, vol.84
, pp. 497-510
-
-
Husson, H.1
Manavalan, P.2
Akmaev, V.R.3
-
23
-
-
33646521976
-
Transcriptome analysis of a rat PKD model: Importance of genes involved in extracellular matrix metabolism
-
Riera M, Burtey S, Fontes M. Transcriptome analysis of a rat PKD model: importance of genes involved in extracellular matrix metabolism. Kidney Int 2006; 69: 1558-1563.
-
(2006)
Kidney Int
, vol.69
, pp. 1558-1563
-
-
Riera, M.1
Burtey, S.2
Fontes, M.3
-
24
-
-
0020048608
-
Murine congenital polycystic kidney disease: A model for studying development of cystic disease
-
Preminger G, Koch W, Fried F et al. Murine congenital polycystic kidney disease: a model for studying development of cystic disease. J Urol 1982; 127: 556-560.
-
(1982)
J Urol
, vol.127
, pp. 556-560
-
-
Preminger, G.1
Koch, W.2
Fried, F.3
-
25
-
-
0022368752
-
A genetically determined murine model of infantile polycystic kidney disease
-
Fry J, Koch W, Jennette J et al. A genetically determined murine model of infantile polycystic kidney disease. J Urol 1985; 134: 828-833.
-
(1985)
J Urol
, vol.134
, pp. 828-833
-
-
Fry, J.1
Koch, W.2
Jennette, J.3
-
26
-
-
0023901949
-
Congenital murine polycystic kidney disease. I. The ontogeny of tubular cyst formation
-
Avner E, Studnicki F, Young M et al. Congenital murine polycystic kidney disease. I. The ontogeny of tubular cyst formation. Pediatr Nephrol 1987; 2: 210-218.
-
(1987)
Pediatr Nephrol
, vol.2
, pp. 210-218
-
-
Avner, E.1
Studnicki, F.2
Young, M.3
-
27
-
-
0037385521
-
Positional cloning of jcpk/bpk locus of the mouse
-
Cogswell C, Price S, Hou X et al. Positional cloning of jcpk/bpk locus of the mouse. Mamm Genome 2003; 14: 242-249.
-
(2003)
Mamm Genome
, vol.14
, pp. 242-249
-
-
Cogswell, C.1
Price, S.2
Hou, X.3
-
28
-
-
0027406817
-
Renal and biliary abnormalities in a new murine model of autosomal recessive polycystic kidney disease
-
Nauta J, Ozawa Y, Sweeney W et al. Renal and biliary abnormalities in a new murine model of autosomal recessive polycystic kidney disease. Pediatr Nephrol 1993; 7: 163-172.
-
(1993)
Pediatr Nephrol
, vol.7
, pp. 163-172
-
-
Nauta, J.1
Ozawa, Y.2
Sweeney, W.3
-
29
-
-
0032030918
-
Epidermal growth factor receptor activity mediates renal cyst formation in polycystic kidney disease
-
Richards W, Sweeney W, BK BY et al. Epidermal growth factor receptor activity mediates renal cyst formation in polycystic kidney disease. J Clin Invest 1998; 101: 935-939.
-
(1998)
J Clin Invest
, vol.101
, pp. 935-939
-
-
Richards, W.1
Sweeney, W.2
BK, B.Y.3
-
30
-
-
0028322016
-
Candidate gene associated with a mutation causing recessive polycystic kidney disease in mice
-
Moyer J, Lee-Tischler M, Kwon H-Y et al. Candidate gene associated with a mutation causing recessive polycystic kidney disease in mice. Science 1994; 264: 1329-1333.
-
(1994)
Science
, vol.264
, pp. 1329-1333
-
-
Moyer, J.1
Lee-Tischler, M.2
Kwon, H.-Y.3
-
31
-
-
24344448706
-
Kinesin family member 12 is a candidate polycystic kidney disease modifier in the cpk mouse
-
Mrug M, Li R, Cui X et al. Kinesin family member 12 is a candidate polycystic kidney disease modifier in the cpk mouse. J Am Soc Nephrol 2005; 16: 905-916.
-
(2005)
J Am Soc Nephrol
, vol.16
, pp. 905-916
-
-
Mrug, M.1
Li, R.2
Cui, X.3
-
32
-
-
33947219859
-
The functional landscape of mouse gene expression
-
Zhang W, Morris QD, Chang R et al. The functional landscape of mouse gene expression. J Biol 2004; 3: 21.
-
(2004)
J Biol
, vol.3
, pp. 21
-
-
Zhang, W.1
Morris, Q.D.2
Chang, R.3
-
33
-
-
37249002059
-
Anatomy of the kidney
-
Brenner B ed, 7th edn, Elsevier Inc, Philadelphia
-
Madsen K, Tisher C. Anatomy of the kidney. In: Brenner B (ed). Brenner and Rector's the Kidney, 7th edn, vol. 1. Elsevier Inc.: Philadelphia, 2004, pp. 4-72.
-
(2004)
Brenner and Rector's the Kidney
, vol.1
, pp. 4-72
-
-
Madsen, K.1
Tisher, C.2
-
35
-
-
0033781807
-
Development of autosomal recessive polycystic kidney disease in BALB/c-cpk/cpk mice
-
Ricker J, Gattone V, Calvet J, Rankin C. Development of autosomal recessive polycystic kidney disease in BALB/c-cpk/cpk mice. J Am Soc Nephrol 2000; 11: 1837-1847.
-
(2000)
J Am Soc Nephrol
, vol.11
, pp. 1837-1847
-
-
Ricker, J.1
Gattone, V.2
Calvet, J.3
Rankin, C.4
-
36
-
-
0037265240
-
Alternative activation of macrophages
-
Gordon S. Alternative activation of macrophages. Nat Rev Immunol 2003; 3: 23-35.
-
(2003)
Nat Rev Immunol
, vol.3
, pp. 23-35
-
-
Gordon, S.1
-
37
-
-
0032416392
-
Complement-dependent clearance of apoptotic cells by human macrophages
-
Mevorach D, Mascarenhas JO, Gershov D, Elkon KB. Complement-dependent clearance of apoptotic cells by human macrophages. J Exp Med 1998; 188: 2313-2320.
-
(1998)
J Exp Med
, vol.188
, pp. 2313-2320
-
-
Mevorach, D.1
Mascarenhas, J.O.2
Gershov, D.3
Elkon, K.B.4
-
38
-
-
0035176461
-
Increased renal expression of monocyte chemoattractant protein-1 and osteopontin in ADPKD in rats
-
Cowley Jr BD, Ricardo SD, Nagao S, Diamond JR. Increased renal expression of monocyte chemoattractant protein-1 and osteopontin in ADPKD in rats. Kidney Int 2001; 60: 2087-2096.
-
(2001)
Kidney Int
, vol.60
, pp. 2087-2096
-
-
Cowley Jr, B.D.1
Ricardo, S.D.2
Nagao, S.3
Diamond, J.R.4
-
39
-
-
33644815875
-
Mechanisms of disease: Autosomal dominant and recessive polycystic kidney diseases
-
quiz 55
-
Torres VE, Harris PC. Mechanisms of disease: autosomal dominant and recessive polycystic kidney diseases. Nat Clin Pract Nephrol 2006; 2: 40-55; quiz 55.
-
(2006)
Nat Clin Pract Nephrol
, vol.2
, pp. 40-55
-
-
Torres, V.E.1
Harris, P.C.2
-
40
-
-
0037103283
-
Complement c3a and c5a induce different signal transduction cascades in endothelial cells
-
Schraufstatter IU, Trieu K, Sikora L et al. Complement c3a and c5a induce different signal transduction cascades in endothelial cells. J Immunol 2002; 169: 2102-2110.
-
(2002)
J Immunol
, vol.169
, pp. 2102-2110
-
-
Schraufstatter, I.U.1
Trieu, K.2
Sikora, L.3
-
41
-
-
0032485940
-
Galpha12 and Galpha13 stimulate Rho-dependent tyrosine phosphorylation of focal adhesion kinase, paxillin, and p130 Crk-associated substrate
-
Needham LK, Rozengurt E. Galpha12 and Galpha13 stimulate Rho-dependent tyrosine phosphorylation of focal adhesion kinase, paxillin, and p130 Crk-associated substrate. J Biol Chem 1998; 273: 14626-14632.
-
(1998)
J Biol Chem
, vol.273
, pp. 14626-14632
-
-
Needham, L.K.1
Rozengurt, E.2
-
42
-
-
0347357836
-
Polycystic kidney disease
-
Wilson P. Polycystic kidney disease. N Engl J Med 2004; 350: 151-164.
-
(2004)
N Engl J Med
, vol.350
, pp. 151-164
-
-
Wilson, P.1
-
43
-
-
0028925552
-
Urokinase plasminogen activator receptor, beta 2-integrins, and Src-kinases within a single receptor complex of human monocytes
-
Bohuslav J, Horejsi V, Hansmann C et al. Urokinase plasminogen activator receptor, beta 2-integrins, and Src-kinases within a single receptor complex of human monocytes. J Exp Med 1995; 181: 1381-1390.
-
(1995)
J Exp Med
, vol.181
, pp. 1381-1390
-
-
Bohuslav, J.1
Horejsi, V.2
Hansmann, C.3
-
44
-
-
0033838665
-
The C5a receptor is expressed by human renal proximal tubular epithelial cells
-
Zahedi R, Braun M, Wetsel RA et al. The C5a receptor is expressed by human renal proximal tubular epithelial cells. Clin Exp Immunol 2000; 121: 226-233.
-
(2000)
Clin Exp Immunol
, vol.121
, pp. 226-233
-
-
Zahedi, R.1
Braun, M.2
Wetsel, R.A.3
-
45
-
-
0032723087
-
C3a is made by proximal tubular HK-2 cells and activates them via the C3a receptor
-
Peake PW, O'Grady S, Pussell BA, Charlesworth JA. C3a is made by proximal tubular HK-2 cells and activates them via the C3a receptor. Kidney Int 1999; 56: 1729-1736.
-
(1999)
Kidney Int
, vol.56
, pp. 1729-1736
-
-
Peake, P.W.1
O'Grady, S.2
Pussell, B.A.3
Charlesworth, J.A.4
-
47
-
-
24144445705
-
Improved statistical tests for differential gene expression by shrinking variance components estimates
-
Cui X, Hwang JT, Qiu J et al. Improved statistical tests for differential gene expression by shrinking variance components estimates. Biostatistics 2005; 6: 59-75.
-
(2005)
Biostatistics
, vol.6
, pp. 59-75
-
-
Cui, X.1
Hwang, J.T.2
Qiu, J.3
-
48
-
-
0036020892
-
A direct approach to false discovery rates
-
Storey J. A direct approach to false discovery rates. J R Stat Soc Ser B 2002; 64: 479-498.
-
(2002)
J R Stat Soc Ser B
, vol.64
, pp. 479-498
-
-
Storey, J.1
-
49
-
-
0042424602
-
Statistical significance for genomewide studies
-
Storey J, Tibshirani R. Statistical significance for genomewide studies. Proc Natl Acad Sci USA 2003; 100: 9440-9445.
-
(2003)
Proc Natl Acad Sci USA
, vol.100
, pp. 9440-9445
-
-
Storey, J.1
Tibshirani, R.2
-
50
-
-
0037129827
-
-
Accurate normalization of realtime quantitative RT-PCR data by geometric averaging of multiple internal control genes, 0034.I-0034.II
-
Vandesompele J, Preter KD, Pattyn F et al. Accurate normalization of realtime quantitative RT-PCR data by geometric averaging of multiple internal control genes. Genome Biol 2002; 3: 0034.I-0034.II.
-
(2002)
Genome Biol
, vol.3
-
-
Vandesompele, J.1
Preter, K.D.2
Pattyn, F.3
|