메뉴 건너뛰기




Volumn 73, Issue 1, 2008, Pages 63-76

Overexpression of innate immune response genes in a model of recessive polycystic kidney disease

Author keywords

Complement; cpk mouse; Innate immune response; Microarray; Recessive PKD

Indexed keywords

COMPLEMENT COMPONENT C3; MACROPHAGE ACTIVATING FACTOR; TRANSCRIPTOME;

EID: 37249025309     PISSN: 00852538     EISSN: 15231755     Source Type: Journal    
DOI: 10.1038/sj.ki.5002627     Document Type: Article
Times cited : (79)

References (50)
  • 1
    • 0027925829 scopus 로고
    • Autosomal dominant polycystic kidney disease
    • Gabow P. Autosomal dominant polycystic kidney disease. N Eng J Med 1993; 329: 332-342.
    • (1993) N Eng J Med , vol.329 , pp. 332-342
    • Gabow, P.1
  • 2
    • 0028278058 scopus 로고
    • The polycystic kidney disease 1 gene encodes a 14 kb transcript and lies within a duplicated region on chromosome 16
    • The European Polycystic Kidney Disease Consortium
    • The European Polycystic Kidney Disease Consortium. The polycystic kidney disease 1 gene encodes a 14 kb transcript and lies within a duplicated region on chromosome 16. Cell 1994; 77: 881-894.
    • (1994) Cell , vol.77 , pp. 881-894
  • 3
    • 0028942745 scopus 로고
    • Analysis of the genomic sequence for the autosomal dominant polycystic kidney disease (PKD1) gene predicts the presence of a leucine-rich repeat
    • The American PKD1 Consortium
    • The American PKD1 Consortium. Analysis of the genomic sequence for the autosomal dominant polycystic kidney disease (PKD1) gene predicts the presence of a leucine-rich repeat. Hum Mol Genet 1995; 4: 575-582.
    • (1995) Hum Mol Genet , vol.4 , pp. 575-582
  • 4
    • 0029002967 scopus 로고
    • Polycystic kidney disease: The complete structure of the PKD1 gene and its protein
    • The International Polycystic Kidney Disease Consortium
    • The International Polycystic Kidney Disease Consortium. Polycystic kidney disease: the complete structure of the PKD1 gene and its protein. Cell 1995; 8: 289-298.
    • (1995) Cell , vol.8 , pp. 289-298
  • 5
    • 15844385078 scopus 로고    scopus 로고
    • PKD2, a gene for polycystic kidney disease that encodes an integral membrane protein
    • Mochizuki T, Wu G, Hayashi T et al. PKD2, a gene for polycystic kidney disease that encodes an integral membrane protein. Science 1996; 272: 1339-1342.
    • (1996) Science , vol.272 , pp. 1339-1342
    • Mochizuki, T.1    Wu, G.2    Hayashi, T.3
  • 6
    • 18344366124 scopus 로고    scopus 로고
    • PKHD1, the polycystic kidney and hepatic disease 1 gene, encodes a novel large protein containing multiple IPT domains and PbH1 repeats
    • Onuchic L, Furu L, Nagasawa Y et al. PKHD1, the polycystic kidney and hepatic disease 1 gene, encodes a novel large protein containing multiple IPT domains and PbH1 repeats. Am J Hum Genet 2002; 70: 1305-1317.
    • (2002) Am J Hum Genet , vol.70 , pp. 1305-1317
    • Onuchic, L.1    Furu, L.2    Nagasawa, Y.3
  • 7
    • 0036509712 scopus 로고    scopus 로고
    • The gene mutated in autosomal recessive polycystic kidney disease encodes a large, receptor-like protein
    • Ward C, Hogan M, Rossetti S et al. The gene mutated in autosomal recessive polycystic kidney disease encodes a large, receptor-like protein. Nat Genet 2002; 30: 259-269.
    • (2002) Nat Genet , vol.30 , pp. 259-269
    • Ward, C.1    Hogan, M.2    Rossetti, S.3
  • 8
    • 0036785149 scopus 로고    scopus 로고
    • The polycystic kidney disease proteins, polycystin-1, polycystin-2, polaris, and cystin, are co-localized in renal cilia
    • Yoder BK, Hou X, Guay-Woodford LM. The polycystic kidney disease proteins, polycystin-1, polycystin-2, polaris, and cystin, are co-localized in renal cilia. J Am Soc Nephrol 2002; 13: 2508-2516.
    • (2002) J Am Soc Nephrol , vol.13 , pp. 2508-2516
    • Yoder, B.K.1    Hou, X.2    Guay-Woodford, L.M.3
  • 9
    • 0037884961 scopus 로고    scopus 로고
    • Kidney-specific inactivation of the KIF3A subunit of kinesin-II inhibits renal ciliogenesis and produces polycystic kidney disease
    • Lin F, Hiesberger T, Cordes K et al. Kidney-specific inactivation of the KIF3A subunit of kinesin-II inhibits renal ciliogenesis and produces polycystic kidney disease. Proc Natl Acad Sci USA 2003; 100: 5286-5291.
    • (2003) Proc Natl Acad Sci USA , vol.100 , pp. 5286-5291
    • Lin, F.1    Hiesberger, T.2    Cordes, K.3
  • 10
    • 0037115494 scopus 로고    scopus 로고
    • Expression analyses and interaction with the anaphase promoting complex protein Apc2 suggest a role for inversin in primary cilia and involvement in the cell cycle
    • Morgan D, Eley L, Sayer J et al. Expression analyses and interaction with the anaphase promoting complex protein Apc2 suggest a role for inversin in primary cilia and involvement in the cell cycle. Hum Mol Gen 2002; 11: 3345-3350.
    • (2002) Hum Mol Gen , vol.11 , pp. 3345-3350
    • Morgan, D.1    Eley, L.2    Sayer, J.3
  • 11
    • 0035159015 scopus 로고    scopus 로고
    • Taulman P, Haycraft C, Balkovetz D, Yoder B. Polaris, a protein involved in left-right axis patterning, localizes to basal bodies and cilia. Mol Biol Cell 2001; 12: 589-599.
    • Taulman P, Haycraft C, Balkovetz D, Yoder B. Polaris, a protein involved in left-right axis patterning, localizes to basal bodies and cilia. Mol Biol Cell 2001; 12: 589-599.
  • 12
    • 0037377655 scopus 로고    scopus 로고
    • Delayed cystogenesis and increased ciliogenesis associated with the re-expression of polaris in Tg737 mutant mice
    • Brown N, Murcia N. Delayed cystogenesis and increased ciliogenesis associated with the re-expression of polaris in Tg737 mutant mice. Kidney Int 2003; 63: 1220-1229.
    • (2003) Kidney Int , vol.63 , pp. 1220-1229
    • Brown, N.1    Murcia, N.2
  • 13
    • 0036177603 scopus 로고    scopus 로고
    • Cystin, a novel cilia-associated protein, is disrupted in the cpk mouse model of polycystic kidney disease
    • Hou X, Mrug M, Yoder B et al. Cystin, a novel cilia-associated protein, is disrupted in the cpk mouse model of polycystic kidney disease. J Clin Invest 2002; 109: 533-540.
    • (2002) J Clin Invest , vol.109 , pp. 533-540
    • Hou, X.1    Mrug, M.2    Yoder, B.3
  • 14
    • 0028227826 scopus 로고
    • Taxol inhibits progression of congenital polycystic kidney disease
    • Woo D, Miao S, Pelayo J, Woolf A. Taxol inhibits progression of congenital polycystic kidney disease. Nature 1994; 368: 750-753.
    • (1994) Nature , vol.368 , pp. 750-753
    • Woo, D.1    Miao, S.2    Pelayo, J.3    Woolf, A.4
  • 15
    • 0035498717 scopus 로고    scopus 로고
    • Bending the MDCK cell primary cilium increases intracellular calcium
    • Praetorius H, Spring K. Bending the MDCK cell primary cilium increases intracellular calcium. J Membr Biol 2001; 184: 71-79.
    • (2001) J Membr Biol , vol.184 , pp. 71-79
    • Praetorius, H.1    Spring, K.2
  • 16
    • 37249019294 scopus 로고    scopus 로고
    • Removal of the MDCK cell primary cilium abolished flow sensing
    • Praetorius H, Spring K. Removal of the MDCK cell primary cilium abolished flow sensing. J Membr Biol 2003; 10: 1-9.
    • (2003) J Membr Biol , vol.10 , pp. 1-9
    • Praetorius, H.1    Spring, K.2
  • 17
    • 0036122434 scopus 로고    scopus 로고
    • Polycystin-2 is an intracellular calcium release channel
    • Koulen P, Cai Y, Geng L et al. Polycystin-2 is an intracellular calcium release channel. Nat Cell Biol 2002; 4: 191-197.
    • (2002) Nat Cell Biol , vol.4 , pp. 191-197
    • Koulen, P.1    Cai, Y.2    Geng, L.3
  • 18
    • 31144441728 scopus 로고    scopus 로고
    • Molecular pathogenesis of autosomal dominant polycystic kidney disease
    • Yoder BK, Mulroy S, Eustace H et al. Molecular pathogenesis of autosomal dominant polycystic kidney disease. Expert Rev Mol Med 2006; 8: 1-22.
    • (2006) Expert Rev Mol Med , vol.8 , pp. 1-22
    • Yoder, B.K.1    Mulroy, S.2    Eustace, H.3
  • 19
    • 0034652247 scopus 로고    scopus 로고
    • Polycystin 1 is required for the structural integrity of blood vessels
    • Kim K, Drummond I, Ibraghimov-Beskrovnaya O et al. Polycystin 1 is required for the structural integrity of blood vessels. Proc Natl Acad Sci USA 2000; 97: 1731-1736.
    • (2000) Proc Natl Acad Sci USA , vol.97 , pp. 1731-1736
    • Kim, K.1    Drummond, I.2    Ibraghimov-Beskrovnaya, O.3
  • 20
    • 16644384500 scopus 로고    scopus 로고
    • The gene expression profile of cyst epithelial cells in autosomal dominant polycystic kidney disease patients
    • Lee JE, Park MH, Park JH. The gene expression profile of cyst epithelial cells in autosomal dominant polycystic kidney disease patients. J Biochem Mol Biol 2004; 37: 612-617.
    • (2004) J Biochem Mol Biol , vol.37 , pp. 612-617
    • Lee, J.E.1    Park, M.H.2    Park, J.H.3
  • 21
    • 3843051389 scopus 로고    scopus 로고
    • New insights into ADPKD molecular pathways using combination of SAGE and microarray technologies
    • Husson H, Manavalan P, Akmaev VR et al. New insights into ADPKD molecular pathways using combination of SAGE and microarray technologies. Genomics 2004; 84: 497-510.
    • (2004) Genomics , vol.84 , pp. 497-510
    • Husson, H.1    Manavalan, P.2    Akmaev, V.R.3
  • 23
    • 33646521976 scopus 로고    scopus 로고
    • Transcriptome analysis of a rat PKD model: Importance of genes involved in extracellular matrix metabolism
    • Riera M, Burtey S, Fontes M. Transcriptome analysis of a rat PKD model: importance of genes involved in extracellular matrix metabolism. Kidney Int 2006; 69: 1558-1563.
    • (2006) Kidney Int , vol.69 , pp. 1558-1563
    • Riera, M.1    Burtey, S.2    Fontes, M.3
  • 24
    • 0020048608 scopus 로고
    • Murine congenital polycystic kidney disease: A model for studying development of cystic disease
    • Preminger G, Koch W, Fried F et al. Murine congenital polycystic kidney disease: a model for studying development of cystic disease. J Urol 1982; 127: 556-560.
    • (1982) J Urol , vol.127 , pp. 556-560
    • Preminger, G.1    Koch, W.2    Fried, F.3
  • 25
    • 0022368752 scopus 로고
    • A genetically determined murine model of infantile polycystic kidney disease
    • Fry J, Koch W, Jennette J et al. A genetically determined murine model of infantile polycystic kidney disease. J Urol 1985; 134: 828-833.
    • (1985) J Urol , vol.134 , pp. 828-833
    • Fry, J.1    Koch, W.2    Jennette, J.3
  • 26
    • 0023901949 scopus 로고
    • Congenital murine polycystic kidney disease. I. The ontogeny of tubular cyst formation
    • Avner E, Studnicki F, Young M et al. Congenital murine polycystic kidney disease. I. The ontogeny of tubular cyst formation. Pediatr Nephrol 1987; 2: 210-218.
    • (1987) Pediatr Nephrol , vol.2 , pp. 210-218
    • Avner, E.1    Studnicki, F.2    Young, M.3
  • 27
    • 0037385521 scopus 로고    scopus 로고
    • Positional cloning of jcpk/bpk locus of the mouse
    • Cogswell C, Price S, Hou X et al. Positional cloning of jcpk/bpk locus of the mouse. Mamm Genome 2003; 14: 242-249.
    • (2003) Mamm Genome , vol.14 , pp. 242-249
    • Cogswell, C.1    Price, S.2    Hou, X.3
  • 28
    • 0027406817 scopus 로고
    • Renal and biliary abnormalities in a new murine model of autosomal recessive polycystic kidney disease
    • Nauta J, Ozawa Y, Sweeney W et al. Renal and biliary abnormalities in a new murine model of autosomal recessive polycystic kidney disease. Pediatr Nephrol 1993; 7: 163-172.
    • (1993) Pediatr Nephrol , vol.7 , pp. 163-172
    • Nauta, J.1    Ozawa, Y.2    Sweeney, W.3
  • 29
    • 0032030918 scopus 로고    scopus 로고
    • Epidermal growth factor receptor activity mediates renal cyst formation in polycystic kidney disease
    • Richards W, Sweeney W, BK BY et al. Epidermal growth factor receptor activity mediates renal cyst formation in polycystic kidney disease. J Clin Invest 1998; 101: 935-939.
    • (1998) J Clin Invest , vol.101 , pp. 935-939
    • Richards, W.1    Sweeney, W.2    BK, B.Y.3
  • 30
    • 0028322016 scopus 로고
    • Candidate gene associated with a mutation causing recessive polycystic kidney disease in mice
    • Moyer J, Lee-Tischler M, Kwon H-Y et al. Candidate gene associated with a mutation causing recessive polycystic kidney disease in mice. Science 1994; 264: 1329-1333.
    • (1994) Science , vol.264 , pp. 1329-1333
    • Moyer, J.1    Lee-Tischler, M.2    Kwon, H.-Y.3
  • 31
    • 24344448706 scopus 로고    scopus 로고
    • Kinesin family member 12 is a candidate polycystic kidney disease modifier in the cpk mouse
    • Mrug M, Li R, Cui X et al. Kinesin family member 12 is a candidate polycystic kidney disease modifier in the cpk mouse. J Am Soc Nephrol 2005; 16: 905-916.
    • (2005) J Am Soc Nephrol , vol.16 , pp. 905-916
    • Mrug, M.1    Li, R.2    Cui, X.3
  • 32
    • 33947219859 scopus 로고    scopus 로고
    • The functional landscape of mouse gene expression
    • Zhang W, Morris QD, Chang R et al. The functional landscape of mouse gene expression. J Biol 2004; 3: 21.
    • (2004) J Biol , vol.3 , pp. 21
    • Zhang, W.1    Morris, Q.D.2    Chang, R.3
  • 33
    • 37249002059 scopus 로고    scopus 로고
    • Anatomy of the kidney
    • Brenner B ed, 7th edn, Elsevier Inc, Philadelphia
    • Madsen K, Tisher C. Anatomy of the kidney. In: Brenner B (ed). Brenner and Rector's the Kidney, 7th edn, vol. 1. Elsevier Inc.: Philadelphia, 2004, pp. 4-72.
    • (2004) Brenner and Rector's the Kidney , vol.1 , pp. 4-72
    • Madsen, K.1    Tisher, C.2
  • 34
  • 35
    • 0033781807 scopus 로고    scopus 로고
    • Development of autosomal recessive polycystic kidney disease in BALB/c-cpk/cpk mice
    • Ricker J, Gattone V, Calvet J, Rankin C. Development of autosomal recessive polycystic kidney disease in BALB/c-cpk/cpk mice. J Am Soc Nephrol 2000; 11: 1837-1847.
    • (2000) J Am Soc Nephrol , vol.11 , pp. 1837-1847
    • Ricker, J.1    Gattone, V.2    Calvet, J.3    Rankin, C.4
  • 36
    • 0037265240 scopus 로고    scopus 로고
    • Alternative activation of macrophages
    • Gordon S. Alternative activation of macrophages. Nat Rev Immunol 2003; 3: 23-35.
    • (2003) Nat Rev Immunol , vol.3 , pp. 23-35
    • Gordon, S.1
  • 37
    • 0032416392 scopus 로고    scopus 로고
    • Complement-dependent clearance of apoptotic cells by human macrophages
    • Mevorach D, Mascarenhas JO, Gershov D, Elkon KB. Complement-dependent clearance of apoptotic cells by human macrophages. J Exp Med 1998; 188: 2313-2320.
    • (1998) J Exp Med , vol.188 , pp. 2313-2320
    • Mevorach, D.1    Mascarenhas, J.O.2    Gershov, D.3    Elkon, K.B.4
  • 38
    • 0035176461 scopus 로고    scopus 로고
    • Increased renal expression of monocyte chemoattractant protein-1 and osteopontin in ADPKD in rats
    • Cowley Jr BD, Ricardo SD, Nagao S, Diamond JR. Increased renal expression of monocyte chemoattractant protein-1 and osteopontin in ADPKD in rats. Kidney Int 2001; 60: 2087-2096.
    • (2001) Kidney Int , vol.60 , pp. 2087-2096
    • Cowley Jr, B.D.1    Ricardo, S.D.2    Nagao, S.3    Diamond, J.R.4
  • 39
    • 33644815875 scopus 로고    scopus 로고
    • Mechanisms of disease: Autosomal dominant and recessive polycystic kidney diseases
    • quiz 55
    • Torres VE, Harris PC. Mechanisms of disease: autosomal dominant and recessive polycystic kidney diseases. Nat Clin Pract Nephrol 2006; 2: 40-55; quiz 55.
    • (2006) Nat Clin Pract Nephrol , vol.2 , pp. 40-55
    • Torres, V.E.1    Harris, P.C.2
  • 40
    • 0037103283 scopus 로고    scopus 로고
    • Complement c3a and c5a induce different signal transduction cascades in endothelial cells
    • Schraufstatter IU, Trieu K, Sikora L et al. Complement c3a and c5a induce different signal transduction cascades in endothelial cells. J Immunol 2002; 169: 2102-2110.
    • (2002) J Immunol , vol.169 , pp. 2102-2110
    • Schraufstatter, I.U.1    Trieu, K.2    Sikora, L.3
  • 41
    • 0032485940 scopus 로고    scopus 로고
    • Galpha12 and Galpha13 stimulate Rho-dependent tyrosine phosphorylation of focal adhesion kinase, paxillin, and p130 Crk-associated substrate
    • Needham LK, Rozengurt E. Galpha12 and Galpha13 stimulate Rho-dependent tyrosine phosphorylation of focal adhesion kinase, paxillin, and p130 Crk-associated substrate. J Biol Chem 1998; 273: 14626-14632.
    • (1998) J Biol Chem , vol.273 , pp. 14626-14632
    • Needham, L.K.1    Rozengurt, E.2
  • 42
    • 0347357836 scopus 로고    scopus 로고
    • Polycystic kidney disease
    • Wilson P. Polycystic kidney disease. N Engl J Med 2004; 350: 151-164.
    • (2004) N Engl J Med , vol.350 , pp. 151-164
    • Wilson, P.1
  • 43
    • 0028925552 scopus 로고
    • Urokinase plasminogen activator receptor, beta 2-integrins, and Src-kinases within a single receptor complex of human monocytes
    • Bohuslav J, Horejsi V, Hansmann C et al. Urokinase plasminogen activator receptor, beta 2-integrins, and Src-kinases within a single receptor complex of human monocytes. J Exp Med 1995; 181: 1381-1390.
    • (1995) J Exp Med , vol.181 , pp. 1381-1390
    • Bohuslav, J.1    Horejsi, V.2    Hansmann, C.3
  • 44
    • 0033838665 scopus 로고    scopus 로고
    • The C5a receptor is expressed by human renal proximal tubular epithelial cells
    • Zahedi R, Braun M, Wetsel RA et al. The C5a receptor is expressed by human renal proximal tubular epithelial cells. Clin Exp Immunol 2000; 121: 226-233.
    • (2000) Clin Exp Immunol , vol.121 , pp. 226-233
    • Zahedi, R.1    Braun, M.2    Wetsel, R.A.3
  • 45
    • 0032723087 scopus 로고    scopus 로고
    • C3a is made by proximal tubular HK-2 cells and activates them via the C3a receptor
    • Peake PW, O'Grady S, Pussell BA, Charlesworth JA. C3a is made by proximal tubular HK-2 cells and activates them via the C3a receptor. Kidney Int 1999; 56: 1729-1736.
    • (1999) Kidney Int , vol.56 , pp. 1729-1736
    • Peake, P.W.1    O'Grady, S.2    Pussell, B.A.3    Charlesworth, J.A.4
  • 46
    • 12344280017 scopus 로고    scopus 로고
    • Summaries of Affymetrix GeneChip probe level data
    • Irizarry R, Bolstad B, Collin F et al. Summaries of Affymetrix GeneChip probe level data. Nucleic Acids Res 2003; 31: e15.
    • (2003) Nucleic Acids Res , vol.31
    • Irizarry, R.1    Bolstad, B.2    Collin, F.3
  • 47
    • 24144445705 scopus 로고    scopus 로고
    • Improved statistical tests for differential gene expression by shrinking variance components estimates
    • Cui X, Hwang JT, Qiu J et al. Improved statistical tests for differential gene expression by shrinking variance components estimates. Biostatistics 2005; 6: 59-75.
    • (2005) Biostatistics , vol.6 , pp. 59-75
    • Cui, X.1    Hwang, J.T.2    Qiu, J.3
  • 48
    • 0036020892 scopus 로고    scopus 로고
    • A direct approach to false discovery rates
    • Storey J. A direct approach to false discovery rates. J R Stat Soc Ser B 2002; 64: 479-498.
    • (2002) J R Stat Soc Ser B , vol.64 , pp. 479-498
    • Storey, J.1
  • 49
    • 0042424602 scopus 로고    scopus 로고
    • Statistical significance for genomewide studies
    • Storey J, Tibshirani R. Statistical significance for genomewide studies. Proc Natl Acad Sci USA 2003; 100: 9440-9445.
    • (2003) Proc Natl Acad Sci USA , vol.100 , pp. 9440-9445
    • Storey, J.1    Tibshirani, R.2
  • 50
    • 0037129827 scopus 로고    scopus 로고
    • Accurate normalization of realtime quantitative RT-PCR data by geometric averaging of multiple internal control genes, 0034.I-0034.II
    • Vandesompele J, Preter KD, Pattyn F et al. Accurate normalization of realtime quantitative RT-PCR data by geometric averaging of multiple internal control genes. Genome Biol 2002; 3: 0034.I-0034.II.
    • (2002) Genome Biol , vol.3
    • Vandesompele, J.1    Preter, K.D.2    Pattyn, F.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.