Genetic and pharmacologic evidence links oxidative stress to ventilator-induced lung injury in mice

American Journal of Respiratory and Critical Care Medicine

Volumn 176, Issue 12, 2007, Pages 1222-1235

  Papaiahgari, Srinivas ^a   Yerrapureddy, Adi ^a   Reddy, Swetha R ^a   Reddy, Narsa M ^a   Dodd O, Jeffery M ^b   Crow, Michael T ^b   Grigoryev, Dimitry N ^b   Barnes, Kathleen ^b   Tuder, Rubin M ^b   Yamamoto, Masayuki ^c   Kensler, Thomas W ^a   Biswal, Shyam ^a   Mitzner, Wayne ^a   Hassoun, Paul M ^b   Reddy, Sekhar P ^a,d  

^a JOHNS HOPKINS UNIVERSITY   (United States)

^b JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c UNIVERSITY OF TSUKUBA   (Japan)

^d Division of Physiology   (United States)

Author keywords

Acute lung injury; Antioxidant enzymes; Inflammation; Mechanical ventilation; Nrf2

Indexed keywords

ANTIOXIDANT; TRANSCRIPTION FACTOR NRF2;

ANIMAL TISSUE; ARTICLE; ARTIFICIAL VENTILATION; GENE EXPRESSION; GENE MUTATION; GENOTYPE; INFLAMMATION; LUNG INJURY; MALE; MOUSE; NEUTROPHIL CHEMOTAXIS; NONHUMAN; OXIDATIVE STRESS; PATHOGENESIS; PRIORITY JOURNAL;

ACETYLCYSTEINE; ANIMALS; ANTIOXIDANTS; CAPILLARY PERMEABILITY; CYTOKINES; DISEASE MODELS, ANIMAL; FREE RADICAL SCAVENGERS; INFLAMMATION; MALE; MICE; MICE, KNOCKOUT; NF-E2-RELATED FACTOR 2; OXIDATIVE STRESS; RESPIRATORY DISTRESS SYNDROME, ADULT; VENTILATORS, MECHANICAL;

EID: 37149047740     PISSN: 1073449X     EISSN: 15354970     Source Type: Journal    
DOI: 10.1164/rccm.200701-060OC     Document Type: Article

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