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Volumn 407, Issue 1-2, 2008, Pages 159-168

Identification and analysis of human RCAN3 (DSCR1L2) mRNA and protein isoforms

Author keywords

Alternative splicing; GST fusion protein assay; Quantitative relative RT PCR; TNNI3; Yeast cotransformation

Indexed keywords

BINDING PROTEIN; CALCINEURIN; GLUTATHIONE; HYBRID PROTEIN; ISOPROTEIN; MESSENGER RNA; PROTEIN TNNI3; SEPHAROSE; TRANSFERASE; TROPONIN I; UNCLASSIFIED DRUG;

EID: 37048999318     PISSN: 03781119     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.gene.2007.10.006     Document Type: Article
Times cited : (12)

References (42)
  • 2
    • 33744832043 scopus 로고    scopus 로고
    • Functional characterization of the calcipressin 1 motif that suppresses calcineurin-mediated NFAT-dependent cytokine gene expression in human T cells
    • Aubareda A., Mulero M.C., and Perez-Riba M. Functional characterization of the calcipressin 1 motif that suppresses calcineurin-mediated NFAT-dependent cytokine gene expression in human T cells. Cell. Signal. 18 (2006) 1430-1438
    • (2006) Cell. Signal. , vol.18 , pp. 1430-1438
    • Aubareda, A.1    Mulero, M.C.2    Perez-Riba, M.3
  • 3
    • 33745899048 scopus 로고    scopus 로고
    • Alternative splicing: new insights from global analyses
    • Blencowe B.J. Alternative splicing: new insights from global analyses. Cell 126 (2006) 37-47
    • (2006) Cell , vol.126 , pp. 37-47
    • Blencowe, B.J.1
  • 4
    • 0346059409 scopus 로고    scopus 로고
    • Calcineurin Abeta gene targeting predisposes the myocardium to acute ischemia-induced apoptosis and dysfunction
    • Bueno O.F., et al. Calcineurin Abeta gene targeting predisposes the myocardium to acute ischemia-induced apoptosis and dysfunction. Circ. Res. 94 (2004) 91-99
    • (2004) Circ. Res. , vol.94 , pp. 91-99
    • Bueno, O.F.1
  • 5
    • 33646044058 scopus 로고    scopus 로고
    • Proteins encoded by human Down syndrome critical region gene 1-like 2 (DSCR1L2) mRNA and by a novel DSCR1L2 mRNA isoform interact with cardiac troponin I (TNNI3)
    • Canaider S., et al. Proteins encoded by human Down syndrome critical region gene 1-like 2 (DSCR1L2) mRNA and by a novel DSCR1L2 mRNA isoform interact with cardiac troponin I (TNNI3). Gene 372 (2006) 128-136
    • (2006) Gene , vol.372 , pp. 128-136
    • Canaider, S.1
  • 6
    • 0037244038 scopus 로고    scopus 로고
    • Genotype, phenotype: upstairs, downstairs in the family of cardiomyopathies
    • Chien K.R. Genotype, phenotype: upstairs, downstairs in the family of cardiomyopathies. J. Clin. Invest. 111 (2003) 175-178
    • (2003) J. Clin. Invest. , vol.111 , pp. 175-178
    • Chien, K.R.1
  • 7
    • 0032529188 scopus 로고    scopus 로고
    • A calcineurin-dependent transcriptional pathway controls skeletal muscle fiber type
    • Chin E.R., et al. A calcineurin-dependent transcriptional pathway controls skeletal muscle fiber type. Genes Dev. 12 (1998) 2499-2509
    • (1998) Genes Dev. , vol.12 , pp. 2499-2509
    • Chin, E.R.1
  • 8
    • 37049021252 scopus 로고    scopus 로고
    • ClustalW: http://www.ebi.ac.uk/clustalw.
  • 9
    • 0017844047 scopus 로고
    • Troponin I from human skeletal and cardiac muscles
    • Cummins P., and Perry S.V. Troponin I from human skeletal and cardiac muscles. Biochem. J. 171 (1978) 251-259
    • (1978) Biochem. J. , vol.171 , pp. 251-259
    • Cummins, P.1    Perry, S.V.2
  • 10
    • 35248837988 scopus 로고    scopus 로고
    • Renaming the DSCR1 /Adapt78 Gene Family as RCAN - Regulators of Calcineurin
    • Davies K.J.A., et al. Renaming the DSCR1 /Adapt78 Gene Family as RCAN - Regulators of Calcineurin. FASEB J. 21 12 (2007) 3023-3028
    • (2007) FASEB J. , vol.21 , Issue.12 , pp. 3023-3028
    • Davies, K.J.A.1
  • 12
    • 37049014822 scopus 로고    scopus 로고
    • Ecgene Browser: http://genome.ewha.ac.kr/ECgene.
  • 13
    • 0027491210 scopus 로고
    • Contributing software to the internet: the Amplify program
    • Engels W.R. Contributing software to the internet: the Amplify program. Trends Biochem. Sci. 18 (1993) 448-450
    • (1993) Trends Biochem. Sci. , vol.18 , pp. 448-450
    • Engels, W.R.1
  • 14
    • 0032894224 scopus 로고    scopus 로고
    • Freeman, W.M., Walker, S.J., Vrana, K.E., 1999. Quantitative RT-PCR: pitfalls and potential. BioTechniques 26, 112-122, 124-125.
  • 15
    • 0034234543 scopus 로고    scopus 로고
    • DSCR1, overexpressed in Down syndrome, is an inhibitor of calcineurin-mediated signaling pathways
    • Fuentes J.J., et al. DSCR1, overexpressed in Down syndrome, is an inhibitor of calcineurin-mediated signaling pathways. Hum. Mol. Genet. 9 (2000) 1681-1690
    • (2000) Hum. Mol. Genet. , vol.9 , pp. 1681-1690
    • Fuentes, J.J.1
  • 16
    • 0028856422 scopus 로고
    • A new human gene from the Down syndrome critical region encodes a proline-rich protein highly expressed in fetal brain and heart
    • Fuentes J.J., Pritchard M.A., Planas A.M., Bosch A., Ferrer I., and Estivill X. A new human gene from the Down syndrome critical region encodes a proline-rich protein highly expressed in fetal brain and heart. Hum. Mol. Genet. 4 (1995) 1935-1944
    • (1995) Hum. Mol. Genet. , vol.4 , pp. 1935-1944
    • Fuentes, J.J.1    Pritchard, M.A.2    Planas, A.M.3    Bosch, A.4    Ferrer, I.5    Estivill, X.6
  • 17
    • 37049024003 scopus 로고    scopus 로고
    • GenBank at NCBI: http://www.ncbi.nlm.nih.gov/Genbank.
  • 18
    • 37049023143 scopus 로고    scopus 로고
    • Genome Browser at UCSC: http://genome.ucsc.edu/cgi-bin/hgGateway.
  • 19
    • 9644278038 scopus 로고    scopus 로고
    • Widespread occurrence of alternative splicing at NAGNAG acceptors contributes to proteome plasticity
    • Erratum in: Nat. Genet. 37:106
    • Hiller M., et al. Widespread occurrence of alternative splicing at NAGNAG acceptors contributes to proteome plasticity. Nat. Genet. 36 (2005) 1255-1257 Erratum in: Nat. Genet. 37:106
    • (2005) Nat. Genet. , vol.36 , pp. 1255-1257
    • Hiller, M.1
  • 20
    • 33644874573 scopus 로고    scopus 로고
    • The UCSC genome browser database: update 2006
    • Database issue
    • Hinrichs A.S., et al. The UCSC genome browser database: update 2006. Nucleic Acids Res 34 (2006) D590-D598 Database issue
    • (2006) Nucleic Acids Res , vol.34
    • Hinrichs, A.S.1
  • 21
    • 0347755531 scopus 로고    scopus 로고
    • The UCSC table browser data retrieval tool
    • Database issue
    • Karolchik D., et al. The UCSC table browser data retrieval tool. Nucleic Acids Res. 32 (2004) D493-D496 Database issue
    • (2004) Nucleic Acids Res. , vol.32
    • Karolchik, D.1
  • 22
    • 4444346326 scopus 로고    scopus 로고
    • Estimating rates of alternative splicing in mammals and invertebrates
    • Kim H., Klein R., Majewski J., and Ott J. Estimating rates of alternative splicing in mammals and invertebrates. Nat. Genet. 36 (2004) 915-916
    • (2004) Nat. Genet. , vol.36 , pp. 915-916
    • Kim, H.1    Klein, R.2    Majewski, J.3    Ott, J.4
  • 23
    • 17844407888 scopus 로고    scopus 로고
    • ECgene: genome-based EST clustering and gene modeling for alternative splicing
    • Kim N., Shin S., and Lee S. ECgene: genome-based EST clustering and gene modeling for alternative splicing. Genome Res. 15 (2005) 566-576
    • (2005) Genome Res. , vol.15 , pp. 566-576
    • Kim, N.1    Shin, S.2    Lee, S.3
  • 25
    • 0030765610 scopus 로고    scopus 로고
    • Mutations in the cardiac troponin I gene associated with hypertrophic cardiomyopathy
    • Kimura A., et al. Mutations in the cardiac troponin I gene associated with hypertrophic cardiomyopathy. Nat. Genet. 16 (1997) 379-382
    • (1997) Nat. Genet. , vol.16 , pp. 379-382
    • Kimura, A.1
  • 26
    • 4344664483 scopus 로고    scopus 로고
    • Calcineurin in animal behavior
    • Lee J.I., and Ahnn J. Calcineurin in animal behavior. Mol. Cell 17 (2004) 390-396
    • (2004) Mol. Cell , vol.17 , pp. 390-396
    • Lee, J.I.1    Ahnn, J.2
  • 27
    • 15844423313 scopus 로고    scopus 로고
    • Molecular cloning of a novel thyroid hormone-responsive gene, ZAKI-4, in human skin fibroblasts
    • Miyazaki T., et al. Molecular cloning of a novel thyroid hormone-responsive gene, ZAKI-4, in human skin fibroblasts. J. Biol. Chem. 271 (1996) 14567-14571
    • (1996) J. Biol. Chem. , vol.271 , pp. 14567-14571
    • Miyazaki, T.1
  • 28
    • 0037238265 scopus 로고    scopus 로고
    • Idiopathic restrictive cardiomyopathy is part of the clinical expression of cardiac troponin I mutations
    • Mogensen J., et al. Idiopathic restrictive cardiomyopathy is part of the clinical expression of cardiac troponin I mutations. J. Clin. Invest. 111 (2003) 209-216
    • (2003) J. Clin. Invest. , vol.111 , pp. 209-216
    • Mogensen, J.1
  • 29
    • 0032540267 scopus 로고    scopus 로고
    • A calcineurin-dependent transcriptional pathway for cardiac hypertrophy
    • Molkentin J.D., et al. A calcineurin-dependent transcriptional pathway for cardiac hypertrophy. Cell 93 (1998) 215-228
    • (1998) Cell , vol.93 , pp. 215-228
    • Molkentin, J.D.1
  • 30
    • 33847124106 scopus 로고    scopus 로고
    • RCAN3, a novel calcineurin inhibitor that down-regulates NFAT-dependent cytokine gene expression
    • Mulero M.A., Aubareda A., Schluter A., and Perez-Riba M. RCAN3, a novel calcineurin inhibitor that down-regulates NFAT-dependent cytokine gene expression. Biochim. Biophys. Acta 1773 (2007) 330-341
    • (2007) Biochim. Biophys. Acta , vol.1773 , pp. 330-341
    • Mulero, M.A.1    Aubareda, A.2    Schluter, A.3    Perez-Riba, M.4
  • 31
    • 2942746423 scopus 로고    scopus 로고
    • Genetic loss of calcineurin blocks mechanical overload-induced skeletal muscle fiber type switching but not hypertrophy
    • Parsons S.A., et al. Genetic loss of calcineurin blocks mechanical overload-induced skeletal muscle fiber type switching but not hypertrophy. J. Biol. Chem. 279 (2004) 26192-26200
    • (2004) J. Biol. Chem. , vol.279 , pp. 26192-26200
    • Parsons, S.A.1
  • 32
    • 2942549111 scopus 로고    scopus 로고
    • A SNP-centric database for the investigation of the human genome
    • Riva A., and Kohane I.S. A SNP-centric database for the investigation of the human genome. BMC Bioinformatics 26 (2004) 5-33
    • (2004) BMC Bioinformatics , vol.26 , pp. 5-33
    • Riva, A.1    Kohane, I.S.2
  • 33
    • 0034708825 scopus 로고    scopus 로고
    • A protein encoded within the Down syndrome critical region is enriched in striated muscles and inhibits calcineurin signaling
    • Rothermel B., Vega R.B., Yang J., Wu H., Bassel-Duby R., and Williams R.S. A protein encoded within the Down syndrome critical region is enriched in striated muscles and inhibits calcineurin signaling. J. Biol. Chem. 275 (2000) 8719-8725
    • (2000) J. Biol. Chem. , vol.275 , pp. 8719-8725
    • Rothermel, B.1    Vega, R.B.2    Yang, J.3    Wu, H.4    Bassel-Duby, R.5    Williams, R.S.6
  • 34
    • 0002053819 scopus 로고
    • The design of primer for PCR
    • Griffin H.G., and Griffin A.M. (Eds), CRC Press, Boca Raton
    • Sharrocks A.D. The design of primer for PCR. In: Griffin H.G., and Griffin A.M. (Eds). PCR Technology - Current Innovations (1994), CRC Press, Boca Raton 5-11
    • (1994) PCR Technology - Current Innovations , pp. 5-11
    • Sharrocks, A.D.1
  • 35
    • 37049019403 scopus 로고    scopus 로고
    • Single Nucleotide Polymorphism Database: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=snp.
  • 36
    • 0037168586 scopus 로고    scopus 로고
    • Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences
    • Strausberg R.L., et al. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Proc. Natl. Acad. Sci. U. S. A. 24 (2002) 16899-16903
    • (2002) Proc. Natl. Acad. Sci. U. S. A. , vol.24 , pp. 16899-16903
    • Strausberg, R.L.1
  • 37
    • 0036021448 scopus 로고    scopus 로고
    • Segmental paralogy in the human genome: a large-scale triplication on 1p, 6p, and 21q
    • Strippoli P., et al. Segmental paralogy in the human genome: a large-scale triplication on 1p, 6p, and 21q. Mamm. Genome 13 (2002) 456-462
    • (2002) Mamm. Genome , vol.13 , pp. 456-462
    • Strippoli, P.1
  • 38
    • 0342314483 scopus 로고    scopus 로고
    • A new gene family including DSCR1 (Down Syndrome Candidate Region 1) and ZAKI-4: characterization from yeast to human and identification of DSCR1-like 2, a novel human member (DSCR1L2)
    • Strippoli P., Lenzi L., Petrini M., Carinci P., and Zannotti M. A new gene family including DSCR1 (Down Syndrome Candidate Region 1) and ZAKI-4: characterization from yeast to human and identification of DSCR1-like 2, a novel human member (DSCR1L2). Genomics 64 (2000) 252-263
    • (2000) Genomics , vol.64 , pp. 252-263
    • Strippoli, P.1    Lenzi, L.2    Petrini, M.3    Carinci, P.4    Zannotti, M.5
  • 39
    • 0034739467 scopus 로고    scopus 로고
    • The murine DSCR1-like (Down syndrome candidate region 1) gene family: conserved synteny with the human orthologous genes
    • Strippoli P., Petrini M., Lenzi L., Carinci P., and Zannotti M. The murine DSCR1-like (Down syndrome candidate region 1) gene family: conserved synteny with the human orthologous genes. Gene 257 (2000) 223-232
    • (2000) Gene , vol.257 , pp. 223-232
    • Strippoli, P.1    Petrini, M.2    Lenzi, L.3    Carinci, P.4    Zannotti, M.5
  • 40
    • 33744976345 scopus 로고    scopus 로고
    • Differential expression of alternatively spliced mRNA forms of the insulin-like growth factor 1 receptor in human neuroendocrine tumors
    • Vitale L., et al. Differential expression of alternatively spliced mRNA forms of the insulin-like growth factor 1 receptor in human neuroendocrine tumors. Oncol Rep. 15 (2006) 1249-1256
    • (2006) Oncol Rep. , vol.15 , pp. 1249-1256
    • Vitale, L.1
  • 42
    • 0035977139 scopus 로고    scopus 로고
    • Forebrain-specific calcineurin knockout selectively impairs bidirectional synaptic plasticity and working/episodic-like memory
    • Zeng H., et al. Forebrain-specific calcineurin knockout selectively impairs bidirectional synaptic plasticity and working/episodic-like memory. Cell 107 (2001) 617-629
    • (2001) Cell , vol.107 , pp. 617-629
    • Zeng, H.1


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