Segmental paralogy in the human genome: A large-scale triplication on 1p, 6p, and 21q

Mammalian Genome

Volumn 13, Issue 8, 2002, Pages 456-462

  Strippoli, Pierluigi ^a   D'Addabbo, Pietro ^a   Lenzi, Luca ^a   Giannone, Sandra ^a   Canaider, Silvia ^a   Casadei, Raffaella ^a   Vitale, Lorenza ^a   Carinci, Paolo ^a   Zannotti, Maria ^a  

^a UNIVERSITY OF BOLOGNA   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

ACUTE MYELOID LEUKEMIA GENE; ARTICLE; CHROMOSOME 1P; CHROMOSOME 21Q; CHROMOSOME 6P; CHROMOSOME DUPLICATION; CLIC GENE; DOWN SYNDROME CANDIDATE REGION 1 LIKE GENE; GENE; HUMAN; HUMAN GENOME; MOLECULAR EVOLUTION; MULTIGENE FAMILY; NUCLEOTIDE SEQUENCE; PARALOGY; RUNT GENE; UNINDEXED SEQUENCE; AMINO ACID SEQUENCE; CHROMOSOME 1; CHROMOSOME 21; CHROMOSOME 6; GENE DUPLICATION; GENETICS; GENOME; MOLECULAR GENETICS; PHYLOGENY;

AMINO ACID SEQUENCE; CHLORIDE CHANNELS; CHROMOSOMES, HUMAN, PAIR 1; CHROMOSOMES, HUMAN, PAIR 21; CHROMOSOMES, HUMAN, PAIR 6; EVOLUTION, MOLECULAR; GENE DUPLICATION; GENOME, HUMAN; HUMAN; MOLECULAR SEQUENCE DATA; MULTIGENE FAMILY; PHOSPHOPROTEINS; PHYLOGENY; SUPPORT, NON-U.S. GOV'T; HUMANS;

CHLORIDE CHANNEL; CLIC6 PROTEIN, HUMAN; PARCHORIN PROTEIN, ORYCTOLAGUS CUNICULUS; PHOSPHOPROTEIN;

EID: 0036021448     PISSN: 09388990     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00335-001-2157-0     Document Type: Article

References (18)

1. The InterPro database, an integrated documentation resource for protein families, domains and functional sites
2. Intracellular potassium and chloride channels: An update
3. DSCR1, overexpressed in Down syndrome, is an inhibitor of calcineurin-mediated signaling pathways
4. The DNA sequence of human chromosome 21
5. Initial sequencing and analysis of the human genome
6. A conserved family of calcineurin regulators
7. AML1, AML2, and AML3, the human members of the runt domain gene-family: cDNA structure, expression, and chromosomal localization
8. Architecture and anatomy of the genomic locus encoding the human leukemia-associated transcription factor RUNX1/AML1
9. Are we polyploids? A brief history of one hypothesis
10. Molecular cloning and characterization of a novel chloride intracellular channel-related protein, parchorin, expressed in water-secreting cells
11. Origin of human chromosome 21 and its consequences: A 50-million-year-old story
12. The neighbor-joining method: A new method for reconstructing phylogenetic trees
13. Our place in the tree of life
14. A new gene family including DSCR1 (Down Syndrome Candidate Region 1) and ZAKI-4: Characterization from yeast to human and identification of DSCR1-like 2, a novel human member (DSCR1L2)
15. The murine DSCR1-like (Down syndrome candidate region 1) gene family: Conserved synteny with the human orthologous genes
16. CLUSTAL W: Improving the sensitivity of progressive multiple sequence alignment through sequence weighting, position-specific gap penalties and weight matrix choice
17. The sequence of the human genome
18. Evolutionary patterns of gene families generated in the early stage of vertebrates