ATRA promotes alpha tocopherol succinate-induced apoptosis in freshly isolated leukemic cells from chronic myeloid leukemic patients

Molecular and Cellular Biochemistry

Volumn 307, Issue 1-2, 2008, Pages 109-119

  Kumar, Surender ^a   Khanduja, Krishan Lal ^a   Verma, Neelam ^a   Verma, Subhash C ^a   Avti, Pramod Kumar ^a   Pathak, Chander Mohan ^a  

^a POSTGRADUATE INSTITUTE OF MEDICAL EDUCATION AND RESEARCH   (India)

Author keywords

Tocopherol succinate; All trans retinoic acid; Apoptosis; Chronic myeloid leukemia; DNA fragmentation; Free radicals; Nitric oxide

Indexed keywords

3 (4,5 DIMETHYL 2 THIAZOLYL) 2,5 DIPHENYLTETRAZOLIUM BROMIDE; ALPHA TOCOPHEROL SUCCINATE; CASPASE 3; DNA FRAGMENT; LIPID; LIPOCORTIN 5; MALONALDEHYDE; NITRIC OXIDE; PHOSPHATIDYLSERINE; REACTIVE OXYGEN METABOLITE; RETINOIC ACID;

ADULT; ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CANCER PATIENT; CELL DEATH; CELL VIABILITY; CHRONIC MYELOID LEUKEMIA; CLINICAL ARTICLE; COMBINATION CHEMOTHERAPY; CONCENTRATION RESPONSE; CONTROLLED STUDY; CYTOSOL; DNA DEGRADATION; DRUG CYTOTOXICITY; DRUG EFFICACY; ENZYME ACTIVITY; FEMALE; FLUORESCENCE ACTIVATED CELL SORTING; HUMAN; HUMAN CELL; IN VITRO STUDY; LEUKEMIA CELL; LIPID PEROXIDATION; LYSOSOME; MALE; MEMBRANE POTENTIAL; MITOCHONDRIAL MEMBRANE; MONOTHERAPY; PERIPHERAL BLOOD MONONUCLEAR CELL;

ADULT; ANTINEOPLASTIC COMBINED CHEMOTHERAPY PROTOCOLS; APOPTOSIS; CASPASE 3; CELL SEPARATION; CELL SURVIVAL; DNA FRAGMENTATION; DRUG EVALUATION, PRECLINICAL; DRUG SYNERGISM; FEMALE; HUMANS; LEUKEMIA, MYELOGENOUS, CHRONIC, BCR-ABL POSITIVE; LIPID PEROXIDATION; LYSOSOMES; MALE; MEMBRANE POTENTIAL, MITOCHONDRIAL; MIDDLE AGED; TRETINOIN; VITAMIN E;

EID: 36949016863     PISSN: 03008177     EISSN: 15734919     Source Type: Journal    
DOI: 10.1007/s11010-007-9590-7     Document Type: Article

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