Effects of vitamin E on the expression of Fas and PCNA proteins in human gastric carcinoma cells and its clinical significance

World Journal of Gastroenterology

Volumn 10, Issue 7, 2004, Pages 945-949

  Wu, Kun ^a   Zhao, Lan ^a   Li, Yao ^a   Shan, Yu Juan ^a   Wu, Li Jie ^a  

^a HARBIN MEDICAL UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA TOCOPHEROL SUCCINATE; CYCLINE; FAS ANTIGEN;

ANTIGEN EXPRESSION; ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CANCER CELL CULTURE; CANCER GROWTH; CANCER INHIBITION; CANCER TISSUE; CARCINOMA CELL; CELL PROLIFERATION; CLINICAL OBSERVATION; CONTROLLED STUDY; GENE EXPRESSION; HISTOPATHOLOGY; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; LYMPH NODE METASTASIS; PREDICTION; PROTEIN ANALYSIS; PROTEIN EXPRESSION; STATISTICAL SIGNIFICANCE; STOMACH CARCINOMA; TUMOR DIFFERENTIATION;

EID: 1842636262     PISSN: 10079327     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (61)

1. Fariss MW, Fortuna MB, Everett CK, Smith JD, Trent DF, Djuric Z. The selective antiproliferation effects of α-tocopheryl hemisuccinate and cholesteryl hemisuccinate on murine leukemia cells result from the action of the intact compounds. Cancer Res 1994; 54: 3346-3357
2. Ottino P, Duncan JR. Effect of alpha-tocopherol succinate on free radical and lipid peroxidation levels in BL6 melanoma cells. Free Radic Biol Med 1997; 22: 1145-1151
3. Prasad KN, Edwards-Prasad J. Effects of tocopherol (vitamin E) acid succinate on morphological alterations and growth inhibition in melanoma cells in culture. Cancer Res 1982; 42: 550-555
4. Zhang Y, Ni J, Messing EM, Chang E, Yang CR, Yeh S. Vitamin E succinate inhibits the function of androgen receptor and the expression of prostate-specific antigen in prostate cancer cells. Proc Natl Acad Sci U S A 2002; 99: 7408-7413
5. Turley JM, Ruscetti FW, Kim SJ, Fu T, Gou FV, Birchenall-Roberts MC. Vitamin E succinate inhibits proliferation of BT-20 human breast cancer cells: Increased binding of cyclin A negatively regulates E2F transactivation activity. Cancer Res 1997; 57: 2668-2675
6. Malafa MP, Neitzel LT. Vitamin E succinate promotes breast cancer tumor dormancy. J Surg Res 2000; 93: 163-170
7. Kline K, Sanders BG. RRR-α-tocopheryl succinate inhibition of lectin-induced T cell proliferation. Nutr Cancer 1993; 19: 241-252
8. Yu W, Sanders BG, Kline K. Modulation of murine EL-4 thymic lymphoma cell proliferation and cytokine production by Vitamin E succinate. Nutr Cancer 1996; 25: 137-149
9. Kline K, Yu WP, Zhao BH, Israel K, Charpentier A, Simmons-Menchaca M, Sanders BG. Vitamin E Succinate: Mechanisms of action as tumor cell growth inhibitor. In: Nutrients in Cancer Prevention and Treatment. Prasad KN. Santamaria L, Williams RM (eds). Totowa.NY:HUmana Press Inc 1995: 39-56
10. Kline K, Yu WP, Sanders BG. Vitamin E: Mechanisms of Action as Tumor Cell Growth Inhibitors. Cancer and Nutrition. Prasad KN, Cole WC (Eds). IOS Press 1998: 37-53
11. Yu W, Sanders BG, Kline K. RRR-alpha-tocopheryl succinate inhibits EL4 thymic lymphoma cell growth by inducing apoptosis and DNA synthesis arrest. Nutr Cancer 1997; 27: 92-101
12. Kim SJ, Bang OS, Lee YS, Kang SS. Production of inducible nitric oxide is required for monocytic differentiation of U937 cells induced by vitamin E-succinate. J Cell Sci 1998; 111(Pt 3): 435-441
13. You H, Yu W, Munoz-Medellin D, Brown PH, Sanders BG, Kline K. Role of extracellular signal-regulated kinase pathway in RRR-alpha-tocopheryl succinate-induced differentiation of human MDA-MB-435 breast cancer cells. Mol Carcinog 2002; 33: 228-236
14. Israel K, Sanders BG, Kline K. RRR-α-tocopheryl succinate inhibits the proliferation of human prostatic tumor cells with defective cell cycle /differentiation pathways. Nutr Cancer 1995; 24: 161-169
15. Yu W, Liao QY, Hantash FM, Sanders BG, Kline K. Activation of extracellular signal-regulated kinase and c-jun-NH(2)-terminal kinase but not p38 mitogen-activated protein kinases is required for RRR-alpha-tocopheryl succinate-induced apoptosis of human breast cancer cells. Cancer Res 2001; 61: 6569-6576
16. Neuzil J, Weber T, Schroder A, Lu M, Ostermann G, Gellert N, Mayne GC, Olejnicka B, Negre-Salvayre A, Sticha M, Coffey RJ, Weber C. Induction of cancer cell apoptosis by alpha-tocopheryl succinate: molecular pathways and structural requirements. FASEB J 2001; 15: 403-415
17. Weber T, Lu M, Andera L, Lahm H, Gellert N, Fariss MW, Korinek V, Sattler W, Ucker DS, Terman A, Schroder A, Erl W, Brunk UT, Coffey RJ, Weber C, Neuzil J. Vitamin E succinate is a potent novel antineoplastic agent with high selectivity and cooperativity with tumor necrosis factor-related apoptosis-inducing ligand (Apo2 ligand) in vivo. Clin Cancer Res 2002; 8: 863-869
18. Yu W, Simmons-Menchaca M, You H, Brown P, Birrer MJ, Sanders BG, Kline K. RRR-α-tocopheryl succinate induction of prolonged activation of c-jun amino-terminal kinase and c-jun during induction of apoptosis in human MDA-MB-435 breast cancer cells. Mol Carcinog 1998; 22: 247-257
19. Neuzil J, Weber T, Gellert N, Weber C. Selective cancer cell killing by alpha-tocopheryl succinate. Br J Cancer 2001; 84: 87-89
20. Hua JS. Effect of Hp: Cell proliferation and apoptosis on stomach cancer. Shijie Huaren Xiaohua Zazhi 1999; 7: 647-648
21. Zhu ZH, Xia ZS, He SG. The effects of ATRA and 5-Fu on telomerase activity and cell growth of gastric cancer cells in vitro. Shijie Huaren Xiaohua Zazhi 2000; 8: 669-673
22. Xia JZ, Zhu ZG, Liu BY, Yan M, Yin HR. Significance of immunohistochemically demonstrated micrometastases to lymph nodes in gastric carcinomas. Shijie Huaren Xiaohua Zazhi 2000; 8: 1113-1116
23. Tu SP, Zhong J, Tan JH, Jiang XH, Qiao MM, Wu YX, Jiang SH. Induction of apoptosis by arsenic trioxide and hydroxy camptothecin in gastric cancer cells in vitro. World J Gastroenterol 2000; 6: 532-539
24. Cai L, Yu SZ, Zhang ZF. Helicobacter pylori infection and risk of gastric cancer in Changle County, Fujian Province, China. World J Gastroenterol 2000; 6: 374-376
25. Yao XX, Yin L, Zhang JY, Bai WY, Li YM, Sun ZC. hTERT expression and cellular immunity in gastric cancer and precancerosis. Shijie Huaren Xiaohua Zazhi 2001; 9: 508-512
26. Xu AG, Li SG, Liu JH, Gan AH. Function of apoptosis and expression of the proteins Bcl-2, p53 and C-myc in the development of gastric cancer. World J Gastroenterol 2001; 7: 403-406
27. Liu DH, Zhang XY, Fan DM, Huang YX, Zhang JS, Huang WQ, Zhang YQ, Huang QS, Ma WY, Chai YB, Jin M. Expression of vascular endothelial growth factor and its role in oncogenesis of human gastric carcinoma. World J Gastroenterol 2001; 7: 500-505
28. Wang X, Lan M, Shi YQ, Lu J, Zhong YX, Wu HP, Zai HH, Ding J, Wu KC, Pan BR, Jin JP, Fan DM. Differential display of vincristine-resistance-related genes in gastric cancer SGC7901 cell. World J Gastroenterol 2002; 8: 54-59
29. Cao WX, Ou JM, Fei XF, Zhu ZG, Yin HR, Yan M, Lin YZ. Methionine-dependence and combination chemotherapy on human gastric cancer cells in vitro. World J Gastroenterol 2002; 8: 230-232
30. Wu K, Liu BH, Zhao DY, Zhao Y. Effect of vitamin E succinate on expression of TGF-β1, c-Jun and JNK1 in human gastric cancer SGC-7901 cells. World J Gastroenterol 2001; 7: 83-87
31. Wu K, Zhao Y, Liu BH, Li Y, Liu F, Guo J, Yu WP. RRR-alpha-tocopheryl succinate inhibits human gastric cancer SGC-7901 cell growth by inducing apoptosis and DNA synthesis arrest. World J Gastroenterol 2002; 8: 26-30
32. Zhao Y, Wu K, Xia W, Shan YJ, Wu LJ, Yu WP. The effects of vitamin E succinate on the expression of c-jun gene and protein in human gastric cancer SGC-7901 cells. World J Gastroenterol 2002; 8: 782-786
33. Wu K, Shan YJ, Zhao Y, Yu JW, Liu BH. Inhibitory effects of RRR-α-tocopheryl succinate on bezo(a)pyrene (B(a)P)-induced forestomach carcinogenesis in female mice. World J Gastroenterol 2001; 7: 60-65
34. Turley JM, Fu T, Ruscetti FW, Mikovits JA, Bertolette DC 3rd, Birchenall-Roberts MC. Vitamin E succinate induces Fas-mediated apoptosis in estrogen receptor-negative human breast cancer cells. Cancer Res 1997; 57: 881-890
35. r 43 000 Fas in VES-triggered apoptosis. Cancer Res 1999; 59: 953-961
36. Israel K, Yu W, Sanders BG, Kline K. Vitamin E succinate induces apoptosis in human prostate cancer cells: Role for Fas in vitamin E succinate-triggered apoptosis. Nutr Cancer 2000; 36: 90-100
37. Wu K, Li Y, Zhao Y, Shan YJ, Xia W, Yu WP, Zhao L. Roles of Fas signaling pathway in vitamin E succinate-induced apoptosis in human gastric cancer SGC-7901 cells. World J Gastroenterol 2002; 8: 982-986
38. Salih HR, Starling GC, Knauff M, Llewellyn MB, Davis PM, Pitts WJ, Aruffo A, Kiener PA. Retinoic acid and vitamin E modulate expression and release of CD178 in carcinoma cells: Consequences for induction of apoptosis in CD95-sensitive cells. Exp Cell Res 2001; 270: 248-258
39. Rubio CA, Jacobsson B. The Fas-FasL system and colorectal tumours. J Clin Pathol 2002; 55: 559-560
40. Peng ZH, Xing TH, Qiu GQ, Tang HM. Relationship between Fas/FasL expression and apoptosis of colon adenocarcinoma cell lines. World J Gastroenterol 2001; 7: 88-92
41. Geng YJ. Molecular signal transduction in vascular cell apoptosis. Cell Res 2001; 11: 253-264
42. Li ZY, Zou SQ. Fas counterattack in cholangiocarcinoma: A mechanism for immune evasion in human hilar cholangiocarcinomas. World J Gastroenterol 2001; 7: 860-863
43. Wajant H. The Fas signaling pathway: More than a paradigm. Science 2002; 296: 1635-1636
44. Hou L, Li Y, Jia YH, Wang B, Xin Y, Ling MY, Lu S. Molecular mechanism about lymphogenous metastasis of hepatocarcinoma cells in mice. World J Gastroenterol 2001; 7: 532-536
45. Yin F, Shi YQ, Zhao WP, Xiao B, Miao JY, Fan DM. Suppression of P-gp induced multiple drug resistance in a drug resistant gastric cancer cell line by overexpression of Fas. World J Gastroenterol 2000; 6: 664-670
46. Xiao B, Shi YQ, Zhao YQ, You H, Wang ZY, Liu XL, Yin F, Qiao TD, Fan DM. Transduction of Fas gene or Bcl-2 antisense RNA sensitizes cultured drug resistant gastric cancer cells to chemotherapeutic drugs. World J Gastroenterol 1998; 4: 421-425
47. Reimer T, Koczan D, Muller H, Friese K, Thiesen HJ, Gerber B. Tumour Fas ligand: Fas ratio greater than 1 is an independent marker of relative resistance to tamoxifen therapy in hormone receptor positive breast cancer. Breast Cancer Res 2002; 4: R9
48. Liu HF, Liu WW, Fang DC, Liu FX, He GY. Clinical significance of Fas antigen expression in gastric carcinoma. World J Gastroenterol 1999; 5: 90-91
49. Zhang W, Meng R, Fu C, Yu D. Gene expression significance of beta-catenin, p53 and PCNA in PJS polyposis. Zhonghua Waike Zazhi 2002; 40: 104-106
50. Lin GY, Chen ZL, Lu CM, Li Y, Ping XJ, Huang R. Immunohistochemical study on p53, H-rasp21, c-erbB-2 protein and PCNA expression in HCC tissues of Han and minority ethnic patients. World J Gastroenterol 2000; 6: 234-238
51. Li JQ, Zhang CQ, Feng KT. PCNA, P53 protein and prognosis in primary liver cancer. China Nati J New Gastroenterol 1996; 2: 220-222
52. Wang YK, Ji XL, Gu YG, Zhang SC, Xiao JH. P53 and PCNA expression in glandular dilatation of gastric mucosa. China Natl J New Gastroenterol 1996; 2: 106-108
53. Qin LX, Tang ZY. The prognostic molecular markers in hepatocellular carcinoma. World J Gastroenterol 2002; 8: 385-392
54. Shen LJ, Zhang HX, Zhang ZJ, Li JY, Chen MQ, Yang WB, Huang R. Detection of HBV, PCNA and GST-pi in hepatocellular carcinoma and chronic liver diseases. World J Gastroenterol 2003; 9: 459-462
55. Yue H, Na YL, Feng XL, Ma SR, Song FL, Yang B. Expression of p57kip2, Rb protein and PCNA and their relationships with clinicopathology in human pancreatic cancer. World J Gastroenterol 2003; 9: 377-380
56. Huang ZH, Fan YF, Xia H, Feng HM, Tang FX. Effects of TNP-470 on proliferation and apoptosis in human colon cancer xenografts in nude mice. World J Gastroenterol 2003; 9: 281-283
57. Chen H, Wang LD, Guo M, Gao SG, Guo HQ, Fan ZM, Li JL. Alterations of p53 and PCNA in cancer and adjacent tissues from concurrent carcinomas of the esophagus and gastric cardia in the same patient in Linzhou, a high incidence area for esophageal cancer in northern China. World J Gastroenterol 2003; 9: 16-21
58. Ouyang GL, Li QF, Peng XX, Liu QR, Hong SG. Effects of tachyplesin on proliferation and differentiation of human hepatocellular carcinoma SMMC-7721 cells. World J Gastroenterol 2002; 8: 1053-1058
59. Jia XD, Han C. Chemoprevention of tea on colorectal cancer induced by dimethylhydrazine in Wistar rats. World J Gastroenterol 2000; 6: 699-703
60. Liu WZ, Zheng X, Shi Y, Dong QJ, Xiao SD. Effect of Helicobacter pylori infection on gastric epithelial proliferation in progression from normal mucosa to gastriccarcinoma. World J Gastroenterol 1998; 4: 246-248
61. Elpek GO, Gelen T, Aksoy NH, Karpuzoglu T, Keles N. Microvessel count, proliferating cell nuclear antigen and Ki-67 indices in gastric adenocarcinoma. Pathol Oncol Res 2000; 6: 59-64