-
1
-
-
0034691261
-
Cardiovascular responses to the isoprostanes iPF(2alpha)-III and iPE(2)-III are mediated via the thromboxane A(2) receptor in vivo
-
Audoly LP, Rocca B, Fabre JE, Koller BH, Thomas D, Loeb AL et al. (2000). Cardiovascular responses to the isoprostanes iPF(2alpha)-III and iPE(2)-III are mediated via the thromboxane A(2) receptor in vivo. Circulation 101: 2833-2840.
-
(2000)
Circulation
, vol.101
, pp. 2833-2840
-
-
Audoly, L.P.1
Rocca, B.2
Fabre, J.E.3
Koller, B.H.4
Thomas, D.5
Loeb, A.L.6
-
2
-
-
0034707105
-
Comparison of upper gastrointestinal toxicity of rofecoxib and naproxen in patients with rheumatoid arthritis. VIGOR Study Group
-
Bombardier C, Laine L, Reicin A, Shapiro D, Burgos-Vargas R, Davis B et al. (2000). Comparison of upper gastrointestinal toxicity of rofecoxib and naproxen in patients with rheumatoid arthritis. VIGOR Study Group. N Engl J Med 343: 1520-1528.
-
(2000)
N Engl J Med
, vol.343
, pp. 1520-1528
-
-
Bombardier, C.1
Laine, L.2
Reicin, A.3
Shapiro, D.4
Burgos-Vargas, R.5
Davis, B.6
-
3
-
-
78651139188
-
The aggregation of blood platelets
-
Born GV, Cross MJ (1963). The aggregation of blood platelets. J Physiol 168: 178-195.
-
(1963)
J Physiol
, vol.168
, pp. 178-195
-
-
Born, G.V.1
Cross, M.J.2
-
4
-
-
19744380776
-
Cardiovascular events associated with rofecoxib in a colorectal adenoma chemoprevention trial
-
Bresalier RS, Sandler RS, Quan H, Bolognese JA, Oxenius B, Horgan K et al. (2005). Cardiovascular events associated with rofecoxib in a colorectal adenoma chemoprevention trial. N Engl J Med 352: 1092-1102.
-
(2005)
N Engl J Med
, vol.352
, pp. 1092-1102
-
-
Bresalier, R.S.1
Sandler, R.S.2
Quan, H.3
Bolognese, J.A.4
Oxenius, B.5
Horgan, K.6
-
5
-
-
0142038871
-
Thromboxane prostanoid receptor in human airway smooth muscle cells: A relevant role in proliferation
-
Capra V, Habib A, Accomazzo MR, Ravasi S, Citro S, Levy-Toledano S et al. (2003). Thromboxane prostanoid receptor in human airway smooth muscle cells: a relevant role in proliferation. Eur J Pharmacol 474: 149-159.
-
(2003)
Eur J Pharmacol
, vol.474
, pp. 149-159
-
-
Capra, V.1
Habib, A.2
Accomazzo, M.R.3
Ravasi, S.4
Citro, S.5
Levy-Toledano, S.6
-
6
-
-
4844225371
-
Mutational analysis of the highly conserved ERY motif of the thromboxane A2 receptor: Alternative role in G protein-coupled receptor signaling
-
Capra V, Veltri A, Foglia C, Crimaldi L, Habib A, Parenti M et al. (2004). Mutational analysis of the highly conserved ERY motif of the thromboxane A2 receptor: alternative role in G protein-coupled receptor signaling. Mol Pharmacol 66: 880-889.
-
(2004)
Mol Pharmacol
, vol.66
, pp. 880-889
-
-
Capra, V.1
Veltri, A.2
Foglia, C.3
Crimaldi, L.4
Habib, A.5
Parenti, M.6
-
7
-
-
0037134011
-
Role of prostacyclin in the cardiovascular response to thromboxane A2
-
Cheng Y, Austin SC, Rocca B, Koller BH, Coffman TM, Grosser T et al. (2002). Role of prostacyclin in the cardiovascular response to thromboxane A2. Science 296: 539-541.
-
(2002)
Science
, vol.296
, pp. 539-541
-
-
Cheng, Y.1
Austin, S.C.2
Rocca, B.3
Koller, B.H.4
Coffman, T.M.5
Grosser, T.6
-
8
-
-
36949032190
-
Anti-anaphylactic action of acetylsalicylate in guinea pig lung
-
Collier HOJ, Hammond AR, Whiteley B (1963). Anti-anaphylactic action of acetylsalicylate in guinea pig lung. Nature 200: 176-178.
-
(1963)
Nature
, vol.200
, pp. 176-178
-
-
Collier, H.O.J.1
Hammond, A.R.2
Whiteley, B.3
-
9
-
-
0017892228
-
Comparative responses of tracheal spirals and parenchymal strips to histamine and carbachol in vitro
-
Drazen JM, Schneider MW(1978). Comparative responses of tracheal spirals and parenchymal strips to histamine and carbachol in vitro. J Clin Invest 61: 1441-1447.
-
(1978)
J Clin Invest
, vol.61
, pp. 1441-1447
-
-
Drazen, J.M.1
Schneider, M.W.2
-
10
-
-
20044381457
-
Preclinical pharmacology of lumiracoxib: A novel selective inhibitor of cyclooxygenase-2
-
Esser R, Berry C, Du Z, Dawson J, Fox A, Fujimoto RA et al. (2005). Preclinical pharmacology of lumiracoxib: a novel selective inhibitor of cyclooxygenase-2. Br J Pharmacol 144: 538-550.
-
(2005)
Br J Pharmacol
, vol.144
, pp. 538-550
-
-
Esser, R.1
Berry, C.2
Du, Z.3
Dawson, J.4
Fox, A.5
Fujimoto, R.A.6
-
11
-
-
0034053647
-
Isoprostanes, novel eicosanoids that produce nociception and sensitize rat sensory neurons
-
Evans AR, Junger H, Southall MD, Nicol GD, Sorkin LS, Broome JT et al. (2000). Isoprostanes, novel eicosanoids that produce nociception and sensitize rat sensory neurons. J Pharmacol Exp Ther 293: 912-920.
-
(2000)
J Pharmacol Exp Ther
, vol.293
, pp. 912-920
-
-
Evans, A.R.1
Junger, H.2
Southall, M.D.3
Nicol, G.D.4
Sorkin, L.S.5
Broome, J.T.6
-
12
-
-
4344578073
-
Comparison of lumiracoxib with naproxen and ibuprofen in the Therapeutic Arthritis Research and Gastrointestinal Event Trial (TARGET), cardiovascular outcomes: Randomised controlled trial
-
Farkouh ME, Kirshner H, Harrington RA, Ruland S, Verheugt FW, Schnitzer TJ et al. (2004). Comparison of lumiracoxib with naproxen and ibuprofen in the Therapeutic Arthritis Research and Gastrointestinal Event Trial (TARGET), cardiovascular outcomes: randomised controlled trial. Lancet 364: 675-684.
-
(2004)
Lancet
, vol.364
, pp. 675-684
-
-
Farkouh, M.E.1
Kirshner, H.2
Harrington, R.A.3
Ruland, S.4
Verheugt, F.W.5
Schnitzer, T.J.6
-
13
-
-
0025249208
-
Evidence for thromboxane receptor mediated contraction of guinea-pig and human airways in vitro by prostaglandin (PG) D2, 9 alpha,11 beta-PGF2 and PGF2 alpha
-
Featherstone RL, Robinson C, Holgate ST, Church MK (1990). Evidence for thromboxane receptor mediated contraction of guinea-pig and human airways in vitro by prostaglandin (PG) D2, 9 alpha,11 beta-PGF2 and PGF2 alpha. Naunyn Schmiedebergs Arch Pharmacol 341: 439-443.
-
(1990)
Naunyn Schmiedebergs Arch Pharmacol
, vol.341
, pp. 439-443
-
-
Featherstone, R.L.1
Robinson, C.2
Holgate, S.T.3
Church, M.K.4
-
14
-
-
0035833502
-
The coxibs, selective inhibitors of cyclooxygenase-2
-
FitzGerald GA, Patrono C (2001). The coxibs, selective inhibitors of cyclooxygenase-2. N Engl J Med 345: 433-442.
-
(2001)
N Engl J Med
, vol.345
, pp. 433-442
-
-
FitzGerald, G.A.1
Patrono, C.2
-
15
-
-
27744528125
-
Prostacyclin protects against elevated blood pressure and cardiac fibrosis
-
Francois H, Athirakul K, Howell D, Dash R, Mao L, Kim HS et al. (2005). Prostacyclin protects against elevated blood pressure and cardiac fibrosis. Cell Metab 2: 201-207.
-
(2005)
Cell Metab
, vol.2
, pp. 201-207
-
-
Francois, H.1
Athirakul, K.2
Howell, D.3
Dash, R.4
Mao, L.5
Kim, H.S.6
-
16
-
-
0025005862
-
The induction and suppression of prostaglandin H2 synthase (cyclooxygenase) in human monocytes
-
Fu JY, Masferrer JL, Seibert K, Raz A, Needleman P (1990). The induction and suppression of prostaglandin H2 synthase (cyclooxygenase) in human monocytes. J Biol Chem 265: 16737-16740.
-
(1990)
J Biol Chem
, vol.265
, pp. 16737-16740
-
-
Fu, J.Y.1
Masferrer, J.L.2
Seibert, K.3
Raz, A.4
Needleman, P.5
-
17
-
-
31044441042
-
Biological basis for the cardiovascular consequences of COX-2 inhibition: Therapeutic challenges and opportunities
-
Grosser T, Fries S, FitzGerald GA (2006). Biological basis for the cardiovascular consequences of COX-2 inhibition: therapeutic challenges and opportunities. J Clin Invest 116: 4-15.
-
(2006)
J Clin Invest
, vol.116
, pp. 4-15
-
-
Grosser, T.1
Fries, S.2
FitzGerald, G.A.3
-
18
-
-
0032569495
-
Randomised controlled trial of Helicobacter pylori eradication in patients on non-steroidal anti-inflammatory drugs: HELP NSAIDs study. Helicobacter eradication for lesion prevention
-
Hawkey CJ, Tulassay Z, Szczepanski L, van Rensburg CJ, Filipowicz-Sosnowska A, Lanas A et al. (1998). Randomised controlled trial of Helicobacter pylori eradication in patients on non-steroidal anti-inflammatory drugs: HELP NSAIDs study. Helicobacter eradication for lesion prevention. Lancet 352: 1016-1021.
-
(1998)
Lancet
, vol.352
, pp. 1016-1021
-
-
Hawkey, C.J.1
Tulassay, Z.2
Szczepanski, L.3
van Rensburg, C.J.4
Filipowicz-Sosnowska, A.5
Lanas, A.6
-
19
-
-
0035859802
-
Effects of selective cyclooxygenase-2 inhibition on vascular responses and thrombosis in canine coronary arteries
-
Hennan JK, Huang J, Barrett TD, Driscoll EM, Willens DE, Park AM et al. (2001). Effects of selective cyclooxygenase-2 inhibition on vascular responses and thrombosis in canine coronary arteries. Circulation 104: 820-825.
-
(2001)
Circulation
, vol.104
, pp. 820-825
-
-
Hennan, J.K.1
Huang, J.2
Barrett, T.D.3
Driscoll, E.M.4
Willens, D.E.5
Park, A.M.6
-
20
-
-
0036606889
-
Are selective COX 2 inhibitors superior to traditional non-steroidal anti-inflammatory drugs?
-
Juni P, Rutjes AW, Dieppe PA (2002). Are selective COX 2 inhibitors superior to traditional non-steroidal anti-inflammatory drugs? BMJ 324: 1287-1288.
-
(2002)
BMJ
, vol.324
, pp. 1287-1288
-
-
Juni, P.1
Rutjes, A.W.2
Dieppe, P.A.3
-
21
-
-
6044245845
-
Lumiracoxib
-
discussion 2247-2248
-
Lyseng-Williamson KA, Curran MP (2004). Lumiracoxib. Drugs 64: 2237-2246; discussion 2247-2248.
-
(2004)
Drugs
, vol.64
, pp. 2237-2246
-
-
Lyseng-Williamson, K.A.1
Curran, M.P.2
-
22
-
-
0033524421
-
Systemic biosynthesis of prostacyclin by cyclooxygenase (COX)-2: The human pharmacology of a selective inhibitor of COX-2
-
McAdam BF, Catella-Lawson F, Mardini IA, Kapoor S, Lawson JA, FitzGerald GA (1999). Systemic biosynthesis of prostacyclin by cyclooxygenase (COX)-2: the human pharmacology of a selective inhibitor of COX-2. Proc Natl Acad Sci USA 96: 272-277.
-
(1999)
Proc Natl Acad Sci USA
, vol.96
, pp. 272-277
-
-
McAdam, B.F.1
Catella-Lawson, F.2
Mardini, I.A.3
Kapoor, S.4
Lawson, J.A.5
FitzGerald, G.A.6
-
23
-
-
33845631867
-
Stronger inhibition by nonsteroid anti-inflammatory drugs of cyclooxygenase-1 in endothelial cells than platelets offers an explanation for increased risk of thrombotic events
-
Mitchell JA, Lucas R, Vojnovic I, Hasan K, Pepper JR, Warner TD (2006). Stronger inhibition by nonsteroid anti-inflammatory drugs of cyclooxygenase-1 in endothelial cells than platelets offers an explanation for increased risk of thrombotic events. FASEB J 20: 2468-2475.
-
(2006)
FASEB J
, vol.20
, pp. 2468-2475
-
-
Mitchell, J.A.1
Lucas, R.2
Vojnovic, I.3
Hasan, K.4
Pepper, J.R.5
Warner, T.D.6
-
24
-
-
0025572704
-
A series of prostaglandin F2-like compounds are produced in vivo in humans by a non-cyclooxygenase, free radical-catalyzed-mechanism
-
Morrow J, Hill K, Burk R, Nammour T, Badr K, Roberts LJI (1990). A series of prostaglandin F2-like compounds are produced in vivo in humans by a non-cyclooxygenase, free radical-catalyzed-mechanism. Proc Natl Acad Sci USA 87: 9383-9387.
-
(1990)
Proc Natl Acad Sci USA
, vol.87
, pp. 9383-9387
-
-
Morrow, J.1
Hill, K.2
Burk, R.3
Nammour, T.4
Badr, K.5
Roberts, L.J.I.6
-
25
-
-
0019061918
-
Ligand: A versatile computerized approach for characterization of ligand-binding systems
-
Munson PJ, Rodbard D (1980). Ligand: a versatile computerized approach for characterization of ligand-binding systems. Anal Biochem 107: 220-239.
-
(1980)
Anal Biochem
, vol.107
, pp. 220-239
-
-
Munson, P.J.1
Rodbard, D.2
-
26
-
-
14944371100
-
Complications of the COX-2 inhibitors parecoxib and valdecoxib after cardiac surgery
-
Nussmeier NA, Whelton AA, Brown MT, Langford RM, Hoeft A, Parlow JL et al. (2005). Complications of the COX-2 inhibitors parecoxib and valdecoxib after cardiac surgery. N Engl J Med 352: 1081-1091.
-
(2005)
N Engl J Med
, vol.352
, pp. 1081-1091
-
-
Nussmeier, N.A.1
Whelton, A.A.2
Brown, M.T.3
Langford, R.M.4
Hoeft, A.5
Parlow, J.L.6
-
27
-
-
0022363178
-
Pharmacological actions of SQ 29548, a novel selective thromboxane antagonist
-
Ogletree ML, Harris DN, Greenberg R, Haslanger MF, Nakane M (1985). Pharmacological actions of SQ 29548, a novel selective thromboxane antagonist. J Pharmacol Exp Ther 234: 435-441.
-
(1985)
J Pharmacol Exp Ther
, vol.234
, pp. 435-441
-
-
Ogletree, M.L.1
Harris, D.N.2
Greenberg, R.3
Haslanger, M.F.4
Nakane, M.5
-
28
-
-
17244374157
-
Frequent monthly use of selected non-prescription and prescription non-narcotic analgesics among US adults
-
Paulose-Ram R, Hirsch R, Dillon C, Gu Q (2005). Frequent monthly use of selected non-prescription and prescription non-narcotic analgesics among US adults. Pharmacoepidemiol Drug Saf 14: 257-266.
-
(2005)
Pharmacoepidemiol Drug Saf
, vol.14
, pp. 257-266
-
-
Paulose-Ram, R.1
Hirsch, R.2
Dillon, C.3
Gu, Q.4
-
29
-
-
0034644396
-
Gastrointestinal toxicity with celecoxib vs nonsteroidal anti-inflammatory drugs for osteoarthritis and rheumatoid arthritis: The CLASS study: a randomized controlled trial. Celecoxib Long-term Arthritis Safety Study
-
Silverstein FE, Faich G, Goldstein JL, Simon LS, Pincus T, Whelton A et al. (2000). Gastrointestinal toxicity with celecoxib vs nonsteroidal anti-inflammatory drugs for osteoarthritis and rheumatoid arthritis: the CLASS study: a randomized controlled trial. Celecoxib Long-term Arthritis Safety Study. JAMA 284: 1247-1255.
-
(2000)
JAMA
, vol.284
, pp. 1247-1255
-
-
Silverstein, F.E.1
Faich, G.2
Goldstein, J.L.3
Simon, L.S.4
Pincus, T.5
Whelton, A.6
-
30
-
-
0015237275
-
Aspirin selectively inhibits prostaglandin production in human platelets
-
Smith JB, Willis AL (1971). Aspirin selectively inhibits prostaglandin production in human platelets. Nat New Biol 231: 235-237.
-
(1971)
Nat New Biol
, vol.231
, pp. 235-237
-
-
Smith, J.B.1
Willis, A.L.2
-
31
-
-
20144365496
-
Cardiovascular risk associated with celecoxib in a clinical trial for colorectal adenoma prevention
-
Solomon SD, McMurray JJ, Pfeffer MA, Wittes J, Fowler R, Finn P et al. (2005). Cardiovascular risk associated with celecoxib in a clinical trial for colorectal adenoma prevention. N Engl J Med 352: 1071-1080.
-
(2005)
N Engl J Med
, vol.352
, pp. 1071-1080
-
-
Solomon, S.D.1
McMurray, J.J.2
Pfeffer, M.A.3
Wittes, J.4
Fowler, R.5
Finn, P.6
-
32
-
-
0141853997
-
Interactions among three classes of mediators explain antigen-induced bronchoconstriction in the isolated perfused and ventilated guinea pig lung
-
Sundstrom E, Lastbom L, Ryrfeldt A, Dahlen S-E (2003). Interactions among three classes of mediators explain antigen-induced bronchoconstriction in the isolated perfused and ventilated guinea pig lung. J Pharmacol Exp Ther 307: 408-418.
-
(2003)
J Pharmacol Exp Ther
, vol.307
, pp. 408-418
-
-
Sundstrom, E.1
Lastbom, L.2
Ryrfeldt, A.3
Dahlen, S.-E.4
-
33
-
-
21044453563
-
Thromboxane A2 and prostaglandin F2alpha mediate inflammatory tachycardia
-
Takayama K, Yuhki K, Ono K, Fujino T, Hara A, Yamada T et al. (2005). Thromboxane A2 and prostaglandin F2alpha mediate inflammatory tachycardia. Nat Med 11: 562-566.
-
(2005)
Nat Med
, vol.11
, pp. 562-566
-
-
Takayama, K.1
Yuhki, K.2
Ono, K.3
Fujino, T.4
Hara, A.5
Yamada, T.6
-
34
-
-
0347627724
-
Proinflammatory actions of thromboxane receptors to enhance cellular immune responses
-
Thomas DW, Rocha PN, Nataraj C, Robinson LA, Spurney RF, Koller BH et al. (2003). Proinflammatory actions of thromboxane receptors to enhance cellular immune responses. J Immunol 171: 6389-6395.
-
(2003)
J Immunol
, vol.171
, pp. 6389-6395
-
-
Thomas, D.W.1
Rocha, P.N.2
Nataraj, C.3
Robinson, L.A.4
Spurney, R.F.5
Koller, B.H.6
-
35
-
-
0023976547
-
Diclofenac sodium. A reappraisal of its pharmacodynamic and pharmacokinetic properties, and therapeutic efficacy
-
Todd PA, Sorkin EM (1988). Diclofenac sodium. A reappraisal of its pharmacodynamic and pharmacokinetic properties, and therapeutic efficacy. Drugs 35: 244-285.
-
(1988)
Drugs
, vol.35
, pp. 244-285
-
-
Todd, P.A.1
Sorkin, E.M.2
-
36
-
-
0015237292
-
Inhibition of prostaglandin synthesis as a mechanism of action for aspirin-like drugs
-
Vane JR (1971). Inhibition of prostaglandin synthesis as a mechanism of action for aspirin-like drugs. Nat New Biol 231: 232-235.
-
(1971)
Nat New Biol
, vol.231
, pp. 232-235
-
-
Vane, J.R.1
-
37
-
-
0034758114
-
Pathogenesis of NSAID-induced gastroduodenal mucosal injury
-
Wallace JL (2001). Pathogenesis of NSAID-induced gastroduodenal mucosal injury. Best Pract Res Clin Gastroenterol 15: 691-703.
-
(2001)
Best Pract Res Clin Gastroenterol
, vol.15
, pp. 691-703
-
-
Wallace, J.L.1
-
38
-
-
0038095583
-
Gastrointestinal effects of nonsteroidal anti-inflammatory drugs
-
Whittle BJ (2003). Gastrointestinal effects of nonsteroidal anti-inflammatory drugs. Fundam Clin Pharmacol 17: 301-313.
-
(2003)
Fundam Clin Pharmacol
, vol.17
, pp. 301-313
-
-
Whittle, B.J.1
-
39
-
-
0033577982
-
Gastrointestinal toxicity of nonsteroidal antiinflammatory drugs
-
Wolfe MM, Lichtenstein DR, Singh G (1999). Gastrointestinal toxicity of nonsteroidal antiinflammatory drugs. N Engl J Med 340: 1888-1899.
-
(1999)
N Engl J Med
, vol.340
, pp. 1888-1899
-
-
Wolfe, M.M.1
Lichtenstein, D.R.2
Singh, G.3
-
40
-
-
26244449273
-
S18886, a selective TP receptor antagonist, inhibits development of atherosclerosis in rabbits
-
Worth NF, Berry CL, Thomas AC, Campbell JH (2005). S18886, a selective TP receptor antagonist, inhibits development of atherosclerosis in rabbits. Atherosclerosis 183: 65-73.
-
(2005)
Atherosclerosis
, vol.183
, pp. 65-73
-
-
Worth, N.F.1
Berry, C.L.2
Thomas, A.C.3
Campbell, J.H.4
|