Statistical optimization of immunoaffinity purification of hepatitis B surface antigen using response surface methodology

Biochemical Engineering Journal

Volumn 38, Issue 1, 2008, Pages 1-8

  Sánchez Romeu, Jorge ^a   País Chanfrau, José Manuel ^a   Pestana Vila, Yanelys ^a   López Larraburo, Ivette ^a   Masso Rodríguez, Yamile ^a   Linares Domínguez, Marbelis ^a   Márquez Perera, Gabriel ^a  

^a CENTER FOR GENETIC ENGINEERING AND BIOTECHNOLOGY   (Cuba)

Author keywords

Affinity; Chromatography; Hepatitis B surface antigen; Monoclonal antibodies; Optimization; Response surfaces methodology

Indexed keywords

CHROMATOGRAPHY; IMMUNOLOGY; MONOCLONAL ANTIBODIES; OPTIMIZATION; STATISTICAL METHODS; SURFACE TREATMENT;

HEPATITIS B SURFACE ANTIGEN; RESPONSE SURFACES METHODOLOGY;

ANTIGENS;

ALCOHOL; DEOXYCHOLATE SODIUM; HEPATITIS B SURFACE ANTIGEN; SODIUM CHLORIDE; THIOCYANATE POTASSIUM;

ACCURACY; ADSORPTION; ARTICLE; DESORPTION; ELUTION; IMMUNOADSORBENT; IMMUNOAFFINITY CHROMATOGRAPHY; IONIC STRENGTH; METHODOLOGY; PRIORITY JOURNAL; STATISTICAL ANALYSIS;

EID: 36849076753     PISSN: 1369703X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bej.2007.05.016     Document Type: Article

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