The interferon-stimulated gene factor 3 complex mediates the inhibitory effect of interferon-β on matrix metalloproteinase-9 expression

FEBS Journal

Volumn 274, Issue 24, 2007, Pages 6456-6468

  Zhao, Xueyan ^a   Nozell, Susan ^a   Ma, Zhendong ^a   Benveniste, Etty N ^a  

^a UNIVERSITY OF ALABAMA AT BIRMINGHAM   (United States)

Author keywords

Gene regulation; Interferon; MMP; Signal transduction; Transcription factors

Indexed keywords

BETA INTERFERON; CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN BINDING PROTEIN; GELATINASE B; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERFERON REGULATORY FACTOR 9; INTERFERON STIMULATED GENE FACTOR 3; PROTEIN P300; STAT1 PROTEIN; STAT2 PROTEIN; TRANSCRIPTION FACTOR SP1;

ACETYLATION; ANALYTIC METHOD; ARTICLE; CHROMATIN IMMUNOPRECIPITATION; CONTROLLED STUDY; ENZYME INHIBITION; GENE EXPRESSION; GENETIC TRANSCRIPTION; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROMOTER REGION;

BINDING SITES; CELL LINE, TUMOR; GENE EXPRESSION; HELA CELLS; HUMANS; IMMUNOBLOTTING; INTERFERON-BETA; INTERFERON-STIMULATED GENE FACTOR 3; INTERFERON-STIMULATED GENE FACTOR 3, GAMMA SUBUNIT; LUCIFERASES; MATRIX METALLOPROTEINASE 9; MITOGEN-ACTIVATED PROTEIN KINASE 1; MITOGEN-ACTIVATED PROTEIN KINASE 3; NF-KAPPA B; PHOSPHORYLATION; PROTEIN BINDING; RECOMBINANT FUSION PROTEINS; RNA, MESSENGER; SIGNAL TRANSDUCTION; STAT1 TRANSCRIPTION FACTOR; STAT2 TRANSCRIPTION FACTOR; TETRADECANOYLPHORBOL ACETATE; TRANS-ACTIVATION (GENETICS); TRANSFECTION; TYROSINE;

EID: 36849063930     PISSN: 1742464X     EISSN: 17424658     Source Type: Journal    
DOI: 10.1111/j.1742-4658.2007.06163.x     Document Type: Article

References (40)

1. Van den Steen PE, Dubois B, Nelissen I, Rudd PM, Dwek RA Opdenakker G (2002) Biochemistry and molecular biology of gelatinase B or matrix metalloproteinase-9 (MMP-9). Crit Rev Biochem Mol Biol 37, 375 536.
2. Rao JS, Yamamoto M, Mohaman S, Gokaslan ZL, Fuller GN, Stetler-Stevenson WG, Rao VH, Liotta LA, Nicolson GL Sawaya RE (1996) Expression and localization of 92 kDa type IV collagenase/gelatinase B (MMP-9) in human gliomas. Clin Exp Metastasis 14, 12 18.
3. Egeblad M Werb Z (2002) New functions for the matrix metalloproteinases in cancer progression. Nat Rev Cancer 2, 161 174.
4. Yan C Boyd DD (2007) Regulation of matrix metalloproteinase gene expression. J Cell Physiol 211, 19 26.
5. Sato H, Kita M Seiki M (1993) v-Src activates the expression of 92-kDa type IV collagenase gene through the AP-1 site and the GT box homologous to retinoblastoma control elements: a mechanism regulating gene expression independent of that by inflammatory cytokines. J Biol Chem 268, 23460 23468.
6. Sato H Seiki M (1993) Regulatory mechanism of 92 kDa type IV collagenase gene expression which is associated with invasiveness of tumor cells. Oncogene 8, 395 405.
7. Gum R, Lengyel E, Juarez J, Chen JH, Sato H, Seiki M Boyd D (1996) Stimulation of 92-kDa gelatinase B promoter activity by ras is mitogen-activated protein kinase kinase 1-independent and requires multiple transcription factor binding sites including closely spaced PEA3/ets and AP-1 sequences. J Biol Chem 271, 10672 10680.
8. Farina AR, Tacconelli A, Vacca A, Maroder M, Gulino A Mackay AR (1999) Transcriptional up-regulation of matrix metalloproteinase-9 expression during spontaneous epithelial to neuroblast phenotype conversion by SK-N-SH neuroblastoma cells, involved in enhanced invasivity, depends upon GT-box and nuclear factor κB elements. Cell Growth Differ 10, 353 367.
9. Ma Z, Shah RC, Chang MJ Benveniste EN (2004) Coordination of cell signaling, chromatin remodeling, histone modifications, and regulator recruitment in human matrix metalloproteinase 9 gene transcription. Mol Cell Biol 24, 5496 5509.
10. Billiau A (2006) Anti-inflammatory properties of type I interferons. Antiviral Res 71, 108 116.
11. Platanias LC (2005) Mechanisms of type-I- and type-II-interferon-mediated signalling. Nat Rev Immunol 5, 375 386.
12. Nozell S, Laver T, Patel K Benveniste EN (2006) Mechanism of IFN-β-mediated inhibition of IL-8 gene expression in astroglioma cells. J Immunol 177, 822 830.
13. Ma Z, Qin H Benveniste EN (2001) Transcriptional suppression of matrix metalloproteinase-9 gene expression by IFN-γ and IFN-β: critical role of STAT-1α. J Immunol 167, 5150 5159.
14. Billiau A, Kieseier BC Hartung HP (2004) Biologic role of interferon β in multiple sclerosis. J Neurol 251 (Suppl. 2), II10-14.
15. Parks WC, Wilson CL Lopez-Boado YS (2004) Matrix metalloproteinases as modulators of inflammation and innate immunity. Nat Rev Immunol 4, 617 629.
16. Opdenakker G, Van den Steen PE Van Damme J (2001) Gelatinase B: a tuner and amplifier of immune functions. Trends Immunol 22, 571 579.
17. Leung S, Qureshi SA, Kerr IM, Darnell JE Jr. Stark GR (1995) Role of STAT2 in the alpha interferon signaling pathway. Mol Cell Biol 15, 1312 1317.
18. Darnell JE Jr., Kerr IM Stark GR (1994) Jak-STAT pathways and transcriptional activation in response to IFNs and other extracellular signaling proteins. Science 264, 1415 1421.
19. Pellegrini S, John J, Shearer M, Kerr IM Stark GR (1989) Use of a selectable marker regulated by alpha interferon to obtain mutations in the signaling pathway. Mol Cell Biol 9, 4605 4612.
20. John J, McKendry R, Pellegrini S, Flavell D, Kerr IM Stark GR (1991) Isolation and characterization of a new mutant human cell line unresponsive to alpha and beta interferons. Mol Cell Biol 11, 4189 4195.
21. McKendry R, John J, Flavell D, Muller M, Kerr IM Stark GR (1991) High-frequency mutagenesis of human cells and characterization of a mutant unresponsive to both alpha and gamma interferons. Proc Natl Acad Sci USA 88, 11455 11459.
22. Shuai K Liu B (2003) Regulation of JAK-STAT signalling in the immune system. Nat Rev Immunol 3, 900 911.
23. Wen Z, Zhong Z Darnell JE Jr. (1995) Maximal activation of transcription by Stat1 and Stat3 requires both tyrosine and serine phosphorylation. Cell 82, 241 250.
24. Qureshi SA, Leung S, Kerr IM, Stark GR Darnell JE Jr. (1996) Function of Stat2 protein in transcriptional activation by alpha interferon. Mol Cell Biol 16, 288 293.
25. Hujanen ES, Vaisanen A, Zheng A, Tryggvason K Turpeenniemi-Hujanen T (1994) Modulation of M (r) 72,000 and M(r) 92,000 type-IV collagenase (gelatinase A and B) gene expression by interferons α and γ in human melanoma. Int J Cancer 58, 582 586.
26. Lu R, Au WC, Yeow WS, Hageman N Pitha PM (2000) Regulation of the promoter activity of interferon regulatory factor-7 gene: activation by interferon and silencing by hypermethylation. J Biol Chem 275, 31805 31812.
27. Lu R, Moore PA Pitha PM (2002) Stimulation of IRF-7 gene expression by tumor necrosis factor α: requirement for NFκB transcription factor and gene accessibility. J Biol Chem 277, 16592 16598.
28. Varinou L, Ramsauer K, Karaghiosoff M, Kolbe T, Pfeffer K, Muller M Decker T (2003) Phosphorylation of the Stat1 transactivation domain is required for full-fledged IFN-γ-dependent innate immunity. Immunity 19, 793 802.
29. Ma Z, Chang MJ, Shah RC Benveniste EN (2005) Interferon-γ-activated STAT-1α suppresses MMP-9 gene transcription by sequestration of the coactivators CBP/p300. J Leukoc Biol 78, 515 523.
30. Sanceau J, Boyd DD, Seiki M Bauvois B (2002) Interferons inhibit tumor necrosis factor-α-mediated matrix metalloproteinase-9 activation via interferon regulatory factor-1 binding competition with NF-κB. J Biol Chem 277, 35766 35775.
31. Chan HM La Thangue NB (2001) p300/CBP proteins: HATs for transcriptional bridges and scaffolds. J Cell Sci 114, 2363 2373.
32. Vo N Goodman RH (2001) CREB-binding protein and p300 in transcriptional regulation. J Biol Chem 276, 13505 13508.
33. Hottiger MO, Felzien LK Nabel GJ (1998) Modulation of cytokine-induced HIV gene expression by competitive binding of transcription factors to the coactivator p300. EMBO J 17, 3124 3134.
34. Ghosh AK, Yuan W, Mori Y, Chen S Varga J (2001) Antagonistic regulation of type I collagen gene expression by interferon-γ and transforming growth factor-β: integration at the level of p300/CBP transcriptional coactivators. J Biol Chem 276, 11041 11048.
35. Nozell S, Ma Z, Wilson C, Shah R Benveniste EN (2004) Class II major histocompatibility complex transactivator (CIITA) inhibits matrix metalloproteinase-9 gene expression. J Biol Chem 279, 38577 38589.
36. Huang WC, Ju TK, Hung MC Chen CC (2007) Phosphorylation of CBP by IKKα promotes cell growth by switching the binding preference of CBP from p53 to NF-κB. Mol Cell 26, 75 87.
37. Yan C, Wang H Boyd DD (2001) KiSS-1 represses 92-kDa type IV collagenase expression by down-regulating NF-κB binding to the promoter as a consequence of IκBα-induced block of p65/p50 nuclear translocation. J Biol Chem 276, 1164 1172.
38. Yan C, Wang H, Toh Y Boyd DD (2003) Repression of 92-kDa type IV collagenase expression by MTA1 is mediated through direct interactions with the promoter via a mechanism, which is both dependent on and independent of histone deacetylation. J Biol Chem 278, 2309 2316.
39. Nair RR, Solway J Boyd DD (2006) Expression cloning identifies transgelin (SM22) as a novel repressor of 92-kDa type IV collagenase (MMP-9) expression. J Biol Chem 281, 26424 26436.
40. Wesemann DR Benveniste EN (2003) STAT-1α and IFN-γ as modulators of TNF-α signaling in macrophages: regulation and functional implications of the TNF receptor 1: STAT-1α complex. J Immunol 171, 5313 5319.