Human Gsα mutant causes pseudohypoparathyroidism type Ia/neonatal diarrhea, a potential cell-specific role of the palmitoylation cycle

Proceedings of the National Academy of Sciences of the United States of America

Volumn 104, Issue 44, 2007, Pages 17424-17429

  Makita, Noriko ^a   Sato, Junichiro ^a   Rondard, Philippe ^b   Fukamachi, Hiroshi ^c   Yuasa, Yasuhito ^c   Aldred, Micheala A ^d,e   Hashimoto, Makiko ^a   Fujita, Toshiro ^a   Iiri, Taroh ^a  

^a UNIVERSITY OF TOKYO   (Japan)

^b INSTITUT DE GÉNOMIQUE FONCTIONNELLE   (France)

^c TOKYO MEDICAL AND DENTAL UNIVERSITY   (Japan)

^d UNIVERSITY OF LEICESTER   (United Kingdom)

^e UNIVERSITY HOSPITALS OF LEICESTER NHS TRUST   (United Kingdom)

Author keywords

Activity; Disease; G protein; Lipid modification; Localization

Indexed keywords

ADENYLATE CYCLASE; CYCLIC AMP; GUANOSINE DIPHOSPHATE; GUANOSINE TRIPHOSPHATE; STIMULATORY GUANINE NUCLEOTIDE BINDING PROTEIN; STIMULATORY GUANINE NUCLEOTIDE BINDING PROTEIN ALPHA; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; BINDING SITE; CONTROLLED STUDY; DIARRHEA; GENE MUTATION; HYDROLYSIS; MOUSE; NEWBORN DISEASE; NONHUMAN; PALMITOYLATION; PHENOTYPE; PRIORITY JOURNAL; PSEUDOHYPOPARATHYROIDISM; RAT; AMINO ACID SEQUENCE; ANIMAL; ARMYWORM; CELL LINE; CHEMISTRY; CLASSIFICATION; DOG; GENETICS; HUMAN; INFANTILE DIARRHEA; LIPOYLATION; METABOLISM; MOLECULAR GENETICS; MUTATION; NEWBORN; PROTEIN BINDING;

RATTUS;

AMINO ACID SEQUENCE; ANIMALS; CELL LINE; CYCLIC AMP; DIARRHEA, INFANTILE; DOGS; GTP-BINDING PROTEIN ALPHA SUBUNITS, GS; HUMANS; INFANT, NEWBORN; LIPOYLATION; MOLECULAR SEQUENCE DATA; MUTATION; PROTEIN BINDING; PSEUDOHYPOPARATHYROIDISM; SPODOPTERA;

EID: 36849054256     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.0708561104     Document Type: Article

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