Activation-induced subcellular redistribution of G(sα)

Molecular Biology of the Cell

Volumn 7, Issue 8, 1996, Pages 1225-1233

  Wedegaertner, Philip B ^a,c   Bourne, Henry R ^a,b   Von Zastrow, Mark ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c THOMAS JEFFERSON UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BETA 2 ADRENERGIC RECEPTOR; STIMULATORY GUANINE NUCLEOTIDE BINDING PROTEIN;

ARTICLE; CELL FRACTIONATION; CELLULAR DISTRIBUTION; CYTOPLASM; ENDOCYTOSIS; ENZYME ACTIVATION; ENZYME ANALYSIS; ENZYME LOCALIZATION; ENZYME SUBUNIT; HUMAN; HUMAN CELL; IMMUNOFLUORESCENCE MICROSCOPY; PRIORITY JOURNAL; PROTEIN TRANSPORT;

EID: 0029779537     PISSN: 10591524     EISSN: None     Source Type: Journal    
DOI: 10.1091/mbc.7.8.1225     Document Type: Article

References (36)

1. s, in transcytosis of the polymeric immunoglobulin receptor. J. Biol. Chem. 268, 25824-25835.
2. Chang, W.-J., Ying, Y-S., Rothberg, K.G., Hooper, N.M., Turner, A.J., Gambliel, H.A., De Gunzburg, J., Mumby, S.M., and Gilman, A.G. (1994). Purification and characterization of smooth muscle cell caveolae. J. Cell Biol. 126, 127-138.
3. Chun, M., Liyange, U.K., Lisanti, M.P., and Lodish, H.J. (1994). Signal transduction of a G-protein-coupled receptor in caveolae: colocalization of endothelin and its receptor with caveolin. Proc. Natl. Acad. Sci. USA 91, 11728-11732.
4. Cullen, B.R. (1987). Use of eukaryotic expression technology in the functional analysis of cloned genes. Methods Enzymol. 152, 684-704.
5. Daukas, G., and Zigmond, S.H. (1985). Inhibition of receptor-mediated but not fluid-phase endocytosis in polymorphonuclear leukocytes. J. Cell Biol. 101, 1673-1679.
6. s protein a subunit after activation by the β-adrenergic receptor or cholera toxin. J. Biol. Chem. 268, 23769-23772.
7. Dunphy, J.T., Greentree, W.K., Manahan, C.L., and Linder, M.E. (1996). G-protein palmitoyltransferase activity is enriched in plasma membranes. J. Biol. Chem. 271, 7154-7159.
8. 187 result in loss of GTPase activity. J. Biol. Chem. 264, 21907-21914.
9. Grady, E.F., Garland, A.M., Gamp, P.D., Lovett, M., Payan, D.G., and Bunnett, N.W. (1995). Delineation of the endocytic pathway of substance P and its seven-transmembrane domain NK1 receptor. Mol. Biol. Cell 6, 509-524.
10. Hermouet, S., de Mazancourt, P., Spiegel, A.M., Farquhar, M.G., and Wilson, B.S. (1992). High-level expression of transfected G-protein alpha i3 subunit is required for plasma membrane targeting and adenylyl cyclase inhibition in NIH 3T3 fibroblasts. FEBS Lett. 312, 223-228.
11. Heuser, J.E., and Anderson, R.G.W. (1989). Hypertonie media inhibit receptor-mediated endocytosis by blocking clathrin-coated pit formation. J. Cell Biol. 108, 389-400.
12. Hoxie, J.A., Ahuja, M., Belmonte, E., Pizarro, S., Parton, R., and Brass, L.F. (1993). Internalization and recycling of activated thrombin receptors. J. Biol. Chem. 268, 13756-13763.
13. 1 cells: relation to G-protein-mediated phospholipase C activation. Proc. Natl. Acad. Sci. USA 92, 8413-8417.
14. Jones, T.L.Z. (1994). Posttranslational modifications and intracellular localization of a subunits. In: G Proteins, ed. A.M. Spiegel, Austin, TX: R.G. Landes, 49-65.
15. s and stimulate adenylyl cyclase in human pituitary tumours. Nature 340, 692-696.
16. s in intact cells alters its abundance, rate of degradation, and membrane avidity. J. Cell Biol. 119, 1297-1307.
17. Lisanti, M.P., Scherer, P.E., Vidurigiene, J., Tang, Z., Hermanowski-Vosatka, A., Tu, Y.-H., Cook, R.F., and Sargiacomo, M. (1994). Characterization of caveolin-rich membrane domains isolated from an endothelial-rich source: implications for human disease. J. Cell Biol. 126, 111-126.
18. 2-adrenergic receptor internalization via the constitutive endocytic pathway into rab5-containing endosomes. J. Cell Sci. 108, 2983-2991.
19. Mumby, S.M., Kleuss, C., and Gilman, A.G. (1994). Receptor regulation of G-protein palmitoylation. Proc. Natl. Acad. Sci. USA 91, 2800-2804.
20. Negishi, M., Hashimoto, H., and Ichikawa, A. (1992). Translocation of a subunits of stimulatory guanine nucleotide-binding proteins through stimulation of the prostacyclin receptor in mouse mastocytoma cells. J. Biol. Chem. 267, 2367-2369.
21. s class of heterotrimeric G protein. Nature 362, 456-458.
22. Pippig, S., Andexinger, S., and Lohse, M.J. (1995). Sequestration and recycling of beta 2-adrenergic receptors permit receptor resensitization. Mol. Pharmacol. 47, 666-676.
23. Ransnäs, L.A., Svoboda, P., Jasper, J.R., and Insel, P.A. (1989). Stimulation of β-adrenergic receptors of S49 lymphoma cells redistributes the α subunit of the stimulatory G protein between cytosol and membranes. Proc. Natl. Acad. Sci. USA 86, 7900-7903.
24. Robinson, L.J., Busconi, L., and Michel, T. (1995). Agonist-modulated palmitoylation of endothelial nitric oxide synthase. J. Biol. Chem. 270, 995-998.
25. s carboxyl-terminal decapeptide. FEBS Lett. 249, 189-194.
26. 1 epithelial cells. J. Cell Biol. 114, 1113-1124.
27. Suryanarayana, S., von Zastrow, M., and Kobilka, B.K. (1992). Identification of intramolecular interactions in adrenergic receptors. J. Biol. Chem. 267, 21991-21994.
28. von Zastrow, M., and Kobilka, B.K. (1992). Ligand-regulated internalization and recycling of human β2-adrenergic receptors between the plasma membrane and endosomes containing transferrin receptors. J. Biol. Chem. 267, 3530-3538.
29. von Zastrow, M., and Kobilka, B.K. (1994). Antagonist-dependent and -independent steps in the mechanism of adrenergic receptor internalization. J. Biol. Chem. 269, 18448-18452.
30. von Zastrow, M., Link, R., Daunt, D., Barsh, G., and Kobilka, B. (1993). Subtype-specific differences in the intracellular sorting of G-profein-coupled receptors. J. Biol. Chem. 268, 763-766.
31. iα1. J. Biol. Chem. 265, 1239-1242.
32. sα. Cell 77, 1063-1070.
33. sα. J. Biol. Chem. 268, 25001-25008.
34. Wilson, B.S., Komuro, M., and Farquhar, M.G. (1994). Cellular variations in heterotrimeric G-protein localization and expression in rat pituitary. Endocrinology 134, 233-243.
35. Yu, S.S., Lefkowitz, R.J., and Hausdorff, W.P. (1993). β-adrenergic receptor sequestration. A potential mechanism of receptor resensitization. J. Biol. Chem. 268, 337-341.
36. Zheng, C-F., and Guan, K.-L. (1994). Cytoplasmic localization of mitogen-activated protein kinase activator MEK. J. Biol. Chem. 269, 19947-19952.