Respiratory responses to thyrotropin-releasing hormone microinjected into the rabbit medulla oblongata

American Journal of Physiology - Regulatory Integrative and Comparative Physiology

Volumn 277, Issue 5 46-5, 1999, Pages

  Mutolo, Donatella ^a   Bongianni, Fulvia ^a   Carfì, Marco ^a   Pantaleo, Tito ^a  

^a UNIVERSITY OF FLORENCE   (Italy)

Author keywords

Area postrema; Botzinger complex; Control of breathing; Medullary respiratory groups

Indexed keywords

PROTIRELIN;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; EXTRACELLULAR MATRIX; HORMONE RELEASE; MALE; MEDULLA OBLONGATA; MICROPHOTOGRAPHY; NONHUMAN; PRIORITY JOURNAL; RABBIT; RESPIRATION CONTROL; STEREOTAXIC SURGERY;

EID: 0032805732     PISSN: 03636119     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajpregu.1999.277.5.r1331     Document Type: Article

References (39)

1. Bianchi, A. L., M. Denavit-Saubié, and J. Champagnat. Central control of breathing in mammals: neuronal circuitry, membrane properties, and neurotransmitters. Physiol. Rev. 75: 1-45, 1995.
2. Bongianni, F., M. Corda, G. A. Fontana, and T. Pantaleo. Chemical activation of caudal medullary expiratory neurones alters the pattern of breathing in the cat. J. Physiol. (Lond.) 474: 497-507, 1994.
3. Bongianni, F., G. Fontana, and T. Pantaleo. Effects of electrical and chemical stimulation of the Bötzinger complex on respiratory activity in the cat. Brain Res. 445: 254-261, 1988.
4. Bongianni, F., G. Fontana, D. Mutolo, and T. Pantaleo. Effects of central chemical drive on poststimulatory respiratory depression of laryngeal origin in the adult cat. Brain Res. Bull. 39: 267-273, 1996.
5. Bongianni, F., D. Mutolo, and T. Pantaleo. Depressant effects on inspiratory and expiratory activity produced by chemical activation of Bötzinger complex neurons in the rabbit. Brain Res. 749: 1-9, 1997.
6. Calzà, L., L. Giardino, S. Ceccatelli, M. Zanni, R. Elde, and T. Hökfelt. Distribution of thyrotropin-releasing hormone receptor messenger RNA in the rat brain: an in situ hybridization study. Neuroscience 51: 891-909, 1992.
7. Connelly, C. A., E. G. Dobbins, and J. L. Feldman. Pre-Bötzinger complex in cats: respiratory neuronal discharge patterns. Brain Res. 590: 337-340, 1992.
8. Cream, C. L., A. Li, and E. E. Nattie. RTN TRH causes prolonged respiratory stimulation. J. Appl. Physiol. 83: 792-799, 1997.
9. Daly, M. D. B. Interactions between respiration and circulation. In: Handbook of Physiology. The Respiratory System. Control of Breathing. Bethesda, MD: Am. Physiol. Soc., 1986, sect. 3, vol. II, chapt. 16, p. 529-594.
10. Dekin, M. S., G. B. Richerson, and P. A. Getting. Thyrotropin-releasing hormone induces rhythmic bursting in neurons of the nucleus tractus solitarius. Science 229: 67-69, 1985.
11. Feldman, J. F., and H. H. Ellenberger. Central coordination of respiratory and cardiovascular control in mammals. Annu. Rev. Physiol. 50: 593-606, 1988.
12. Fornal, C., S. Auerbach, and B. L. Jacobs. Activity of serotonin-containing neurons in nucleus raphe magnus in freely moving cats. Exp. Neurol. 88: 590-608, 1985.
13. Greer, J. J., Z. Al-Zubaidy, and J. E. Carter. Thyrotropin-releasing hormone stimulates perinatal rat respiration in vitro. Am. J. Physiol. 271 (Regulatory Integrative Comp. Physiol. 40): R1160-R1164, 1996.
14. Hedner, J., T. Hedner, P. Wessberg, D. Lundberg, and J. Jonason. Effects of TRH and TRH analogues on the central regulation of breathing in the rat. Acta Physiol. Scand. 117: 427-437, 1983.
15. Homma, I., M. Oouchi, and S. Ichikawa. Facilitation of inspiration by intracerebroventricular injection of thyrotropin-releasing hormone in rabbits. Neurosci. Lett. 44: 265-269, 1984.
16. Hornby, P. J., C. D. Rossiter, S. V. Pineo, W. P. Norman, E. K. Friedman, S. Benjamin, and R. A. Gillis. TRH: immunocytochemical distribution in vagal nuclei of the cat and physiological effects of microinjection. Am. J. Physiol. 257 (Gastrointest. Liver Physiol. 20): G454-G462, 1989.
17. Iwase, M., S. Shioda, Y. Nakai, and I. Homma. Immunocytochemistry of thyrotropin-releasing hormone in the rabbit medulla oblongata. Brain Res. Bull. 26: 49-57, 1991.
18. Jiang, C., and E. Shen. Respiratory neurons in the medulla of the rabbit: distribution, discharge patterns and spinal projections. Brain Res. 541: 284-292, 1991.
19. Livingston, C. A., and A. J. Berger. Response of neurons in the dorsal motor nucleus of the vagus to thyrotropin-releasing hormone. Brain Res. 621: 97-105, 1993.
20. Manaker, S., and G. Rizio. Autoradiographic localization of thyrotropin-releasing hormone and substance P receptors in the rat dorsal vagal complex. J. Comp. Neurol. 290: 516-526, 1989.
21. McCown, T. J., J. A. Hedner, A. C. Towle, G. R. Breese, and R. A. Mueller. Brainstem localization of a thyrotropin-releasing hormone-induced change in respiratory function. Brain Res. 373: 189-196, 1986.
22. Merchenthaler, I., V. Csernus, C. Csontos, P. Petrusz, and B. Mess. New data on the immunocytochemical localization of thyrotropin-releasing hormone in the rat central nervous system. Am. J. Anat. 181: 359-376, 1988.
23. Murakoshi, T., T. Suzue, and S. Tamai. A pharmacological study on respiratory rhythm in the isolated brainstem-spinal cord preparation of the newborn rat. Br. J. Pharmacol. 86: 95-104, 1985.
24. Nicholson, C. Diffusion from an injected volume of a substance in brain tissue with arbitrary volume fraction and tortuosity. Brain Res. 333: 325-329, 1985.
25. Nink, M., U. Krause, H. Lehnert, W. Heuberger, I. Huber, R. Schulz, G. Hommel, and J. Beyer. Thyrotropin-releasing hormone has stimulatory effects on ventilation in humans. Acta Physiol. Scand. 141: 309-318, 1991.
26. Paakkari, I., M.-L. Nurminen, and A.-L. Sirén. Cardioventilator effects of TRH in anaesthetized rats: role of the brain stem. Eur. J. Pharmacol. 122: 131-134, 1986.
27. Raggenbass, M., C. Vozzi, E. Tribollet, M. Dubois-Dauphin, and J. J. Dreifuss. Thyrotropin-releasing hormone causes direct excitation of dorsal vagal and solitary tract neurones in rat brainstem slices. Brain Res. 530: 85-90, 1990.
28. Rekling, J. C., J. Champagnat, and M. Denavit-Saubiè. Thyrotropin-releasing hormone (TRH) depolarizes a subset of inspiratory neurons in the newborn mouse brain stem in vitro. J. Neurophysiol. 75: 811-819, 1996.
29. Rekling, J. C., and J. L. Feldman. PreBötzinger complex and pacemaker neurons: hypothesized site and kernel for respiratory rhythm generation. Annu. Rev. Physiol. 60: 385-405, 1998.
30. Sawyer, C. H., J. W. Everett, and J. D. Green. The rabbit diencephalon in stereotaxic coordinates. J. Comp. Neurol. 101: 801-824, 1954.
31. Schwarzacher, S. W., J. C. Smith, and D. W. Richter. Pre-Bötzinger complex in the cat. J. Neurophysiol. 73: 1452-1461, 1995.
32. Shek, J. W., G. Y. Wen, and H. M. Wisniewski. Atlas of the Rabbit Brain and Spinal Cord. Basel: Karger, 1986.
33. Smith, J. C., H. H. Ellenberger, K. Ballanyi, D. W. Richter, and J. L. Feldman. Pre-Bötzinger complex: a brainstem region that may generate respiratory rhythm in mammals. Science 254: 726-729, 1991.
34. Spyer, K. M. Central nervous mechanisms contributing to cardiovascular control. J. Physiol. (Lond.) 474: 1-19, 1994.
35. Srinivasan, M., F. Bongianni, G. A. Fontana, and T. Pantaleo. Respiratory responses to electrical and chemical stimulation of the area postrema in the rabbit. J. Physiol. (Lond.) 463: 409-420, 1993.
36. Sun, Q.-J., I. Llewellyn-Smith, J. Minson, L. Arnolda, J. Chalmers, and P. Pilowsky. Thyrotropin-releasing hormone immunoreactive boutons form close appositions with medullary expiratory neurons in the rat. Brain Res. 715: 136-144, 1996.
37. Sun, Q.-J., P. Pilowsky, and I. Llewellyn-Smith. Thyrotropin-releasing hormone inputs are preferentially directed towards respiratory motoneurons in rat nucleus ambiguus. J. Comp. Neurol. 362: 320-330, 1995.
38. Von Euler, C. Brain stem mechanisms for generation and control of breathing pattern. In: Handbook of Physiology. The Respiratory System. Control of Breathing. Bethesda, MD: Am. Physiol. Soc., 1986, sect. 3, vol. II, chapt. 1, p. 1-67.
39. Yamamoto, Y., H. Lagercrantz, and C. von Euler. Effects of substance P and TRH on ventilation and pattern of breathing in newborn rabbits. Acta Physiol. Scand. 113: 541-543, 1981.