KNOBLE: A knowledge-based approach for the design and synthesis of readily accessible small-molecule chemical probes to test protein binding

Angewandte Chemie - International Edition

Volumn 46, Issue 47, 2007, Pages 9105-9109

  Gerlach, Christof ^a   Münzel, Martin ^a   Baum, Bernhard ^a   Gerber, Hans Dieter ^a   Craan, Tobias ^a   Diederich, Wibke E ^a   Klebe, Gerhard ^a  

^a PHILIPPS UNIVERSITY MARBURG   (Germany)

Author keywords

Combinatorial chemistry; Drug design; Ligand design; Thrombin

Indexed keywords

CRYSTAL STRUCTURE; DRUG PRODUCTS; LIGANDS; MOLECULAR STRUCTURE; SYNTHESIS (CHEMICAL);

COMBINATORIAL CHEMISTRY; DRUG DESIGN; LIGAND DESIGN;

PROTEINS;

ARTICLE; COMBINATORIAL CHEMISTRY; DRUG DESIGN; MOLECULAR PROBE; PROTEIN BINDING;

COMBINATORIAL CHEMISTRY TECHNIQUES; DRUG DESIGN; MOLECULAR PROBES; PROTEIN BINDING;

EID: 36848998994     PISSN: 14337851     EISSN: None     Source Type: Journal    
DOI: 10.1002/anie.200703323     Document Type: Article

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