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Volumn 7, Issue 7, 2006, Pages 1048-1055

An efficient method for the synthesis of peptide aldehyde libraries employed in the discovery of reversible SARS coronavirus main protease (SARS-Cov Mpro) inhibitors

(9) Al Gharabli, Samer I a,e Ali Shah, Syed T a Weik, Steffen a Schmidt, Marco F a,d Mesters, Jeroen R b Kuhn, Daniel c Klebe, Gerhard c Hilgenfeld, Rolf b Rademann, Jörg a,d

a LEIBNIZ INSTITUT FÜR MOLEKULARE PHARMAKOLOGIE (Germany)

b UNIVERSITY OF LÜBECK (Germany)

c PHILIPPS UNIVERSITY MARBURG (Germany)

d FREIE UNIVERSITÄT BERLIN (Germany)

e GERMAN JORDANIAN UNIVERSITY (Jordan)

Author keywords

Aldehydes; Cysteine proteases; Inhibitors; SARS; Solid phase synthesis; Viruses

Indexed keywords

ALDEHYDE; PROTEINASE INHIBITOR;

ARTICLE; CORONAVIRUS; DESS MARTIN OXIDATION; IC 50; PEPTIDE SYNTHESIS; PRIORITY JOURNAL; RACEMIZATION; SEVERE ACUTE RESPIRATORY SYNDROME; SOLID;

ALDEHYDES; HUMANS; MAGNETIC RESONANCE SPECTROSCOPY; MOLECULAR PROBE TECHNIQUES; PEPTIDE LIBRARY; PROTEASE INHIBITORS; SARS VIRUS;

SARS CORONAVIRUS;

EID: 33745906224 PISSN: 14394227 EISSN: 14397633 Source Type: Journal
DOI: 10.1002/cbic.200500533 Document Type: Article

Times cited : (51)

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