A Nurr1 point mutant, implicated in Parkinson's disease, uncouples ERK1/2-dependent regulation of tyrosine hydroxylase transcription

Neurobiology of Disease

Volumn 29, Issue 1, 2008, Pages 117-122

  Jacobsen, Kirsten X ^a,b   MacDonald, Heather ^a   Lemonde, Sylvie ^a   Daigle, Mireille ^a   Grimes, David A ^a,b   Bulman, Dennis E ^a,b   Albert, Paul R ^a,b  

^a OTTAWA HOSPITAL RESEARCH INSTITUTE   (Canada)

^b UNIVERSITY OF OTTAWA   (Canada)

Author keywords

Development; Dopamine; Orphan nuclear receptor; Phosphorylation; Point Mutation; Transcription

Indexed keywords

MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; NUCLEAR RECEPTOR RELATED FACTOR 1; QUINPIROLE; TYROSINE 3 MONOOXYGENASE;

AMINO ACID SEQUENCE; ARTICLE; CELL LINE; CONTROLLED STUDY; ENZYME REGULATION; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; MUTANT; NEUROBLASTOMA CELL; PARKINSON DISEASE; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; TRANSCRIPTION INITIATION;

CELL LINE, TRANSFORMED; CYSTEINE; DNA-BINDING PROTEINS; DOPAMINE AGONISTS; DRUG INTERACTIONS; ENZYME ACTIVATION; ENZYME INHIBITORS; FLAVONOIDS; GENE EXPRESSION REGULATION; HUMANS; MITOGEN-ACTIVATED PROTEIN KINASE 3; MUTATION; NEUROBLASTOMA; QUINPIROLE; SERINE; TRANSCRIPTION FACTORS; TRANSFECTION; TYROSINE 3-MONOOXYGENASE;

EID: 36549088630     PISSN: 09699961     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.nbd.2007.08.003     Document Type: Article

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