메뉴 건너뛰기




Volumn 70, Issue 5, 1998, Pages 2139-2146

Activation of microtubule-associated protein kinase (Erk) and p70 S6 kinase by D2 dopamine receptors

Author keywords

D2 receptor; Dopamine; Microtubule associated protein kinase; p70 S6 kinase

Indexed keywords

DOPAMINE 2 RECEPTOR; GUANINE NUCLEOTIDE BINDING PROTEIN; INHIBITORY GUANINE NUCLEOTIDE BINDING PROTEIN; PROTEIN KINASE; PROTEIN KINASE (CALCIUM,CALMODULIN);

EID: 0031969728     PISSN: 00223042     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1471-4159.1998.70052139.x     Document Type: Article
Times cited : (72)

References (59)
  • 2
    • 0029257329 scopus 로고
    • Inactivation of p42 MAP kinase by protein phosphatase 2A and a protein tyrosine phosphatase, but not CL100, in various cell lines
    • Alessi D. R., Gomez N., Moorhead G., Lewis T., Keyse S. M., and Cohen P. (1995) Inactivation of p42 MAP kinase by protein phosphatase 2A and a protein tyrosine phosphatase, but not CL100, in various cell lines. Curr. Biol. 5, 283-295.
    • (1995) Curr. Biol. , vol.5 , pp. 283-295
    • Alessi, D.R.1    Gomez, N.2    Moorhead, G.3    Lewis, T.4    Keyse, S.M.5    Cohen, P.6
  • 3
    • 0027432424 scopus 로고
    • Wortmannin is a potent phosphatidylinositol 3-kinase inhibitor: The role of phosphatidylinositol 3,4,5-trisphosphate in neutrophil responses
    • Arcaro A. and Wymann M. P. (1993) Wortmannin is a potent phosphatidylinositol 3-kinase inhibitor: the role of phosphatidylinositol 3,4,5-trisphosphate in neutrophil responses. Biochem. J. 296, 297-301.
    • (1993) Biochem. J. , vol.296 , pp. 297-301
    • Arcaro, A.1    Wymann, M.P.2
  • 4
    • 0029060537 scopus 로고
    • Activation of the mitogen-activated protein kinase cascade by pertussis-toxin-sensitive and pertussis-toxin-insensitive pathways in cultured ventricular cardiomyocytes
    • Bogoyevitch M. A., Clerk A., and Sugden P. H. (1995) Activation of the mitogen-activated protein kinase cascade by pertussis-toxin-sensitive and pertussis-toxin-insensitive pathways in cultured ventricular cardiomyocytes. Biochem. J. 309, 437-443.
    • (1995) Biochem. J. , vol.309 , pp. 437-443
    • Bogoyevitch, M.A.1    Clerk, A.2    Sugden, P.H.3
  • 5
    • 0029831167 scopus 로고    scopus 로고
    • Direct inhibition of the signalling functions of the mammalian target of rapamycin by the phosphoinositide 3-kinase inhibitors, wortmannin and LY294002
    • Brunn G. J., Williams J., Sabers C., Weiderrecht G., Lawrence J. C., and Abraham R. T. (1996) Direct inhibition of the signalling functions of the mammalian target of rapamycin by the phosphoinositide 3-kinase inhibitors, wortmannin and LY294002. EMBO J. 15, 5256-5267.
    • (1996) EMBO J. , vol.15 , pp. 5256-5267
    • Brunn, G.J.1    Williams, J.2    Sabers, C.3    Weiderrecht, G.4    Lawrence, J.C.5    Abraham, R.T.6
  • 8
    • 0028308412 scopus 로고
    • Phosphatidylinositol 3-kinase activation is required for insulin stimulation of pp70 S6 kinase, DNA synthesis and glucose transporter translocation
    • Cheatham B., Vlahos C. J., Cheatham L., Wang L., Blenis J., and Kahn C. R. (1994) Phosphatidylinositol 3-kinase activation is required for insulin stimulation of pp70 S6 kinase, DNA synthesis and glucose transporter translocation. Mol. Cell. Biol. 14, 4902-4911.
    • (1994) Mol. Cell. Biol. , vol.14 , pp. 4902-4911
    • Cheatham, B.1    Vlahos, C.J.2    Cheatham, L.3    Wang, L.4    Blenis, J.5    Kahn, C.R.6
  • 9
    • 0026659046 scopus 로고
    • Rapamycin-FKBP specifically blocks growth-dependent activation of and signaling by the 70 kd S6 protein kinases
    • Chung J., Kuo C. J., Crabtree G. R., and Blenis J. (1992) Rapamycin-FKBP specifically blocks growth-dependent activation of and signaling by the 70 kd S6 protein kinases. Cell 69, 1227-1236.
    • (1992) Cell , vol.69 , pp. 1227-1236
    • Chung, J.1    Kuo, C.J.2    Crabtree, G.R.3    Blenis, J.4
  • 10
    • 0028178928 scopus 로고
    • PDGF- and insulin-dependent pp70s6k activation mediated by phosphatidylinositol 3-OH kinase
    • Chung J., Grammer T. C., Lemon K. P., Kazlauskas A., and Blenis J. (1994) PDGF- and insulin-dependent pp70s6k activation mediated by phosphatidylinositol 3-OH kinase. Nature 370, 71-75.
    • (1994) Nature , vol.370 , pp. 71-75
    • Chung, J.1    Grammer, T.C.2    Lemon, K.P.3    Kazlauskas, A.4    Blenis, J.5
  • 11
    • 0029043582 scopus 로고
    • How MAP kinases are regulated
    • Cobb M. H. and Goldsmith E. J. (1995) How MAP kinases are regulated. J. Biol. Chem. 270, 14843-14846.
    • (1995) J. Biol. Chem. , vol.270 , pp. 14843-14846
    • Cobb, M.H.1    Goldsmith, E.J.2
  • 12
    • 0027304607 scopus 로고
    • Extracellular signals and reversible protein phosphorylation: What to Mek of it all
    • Crews C. M. and Erikson R. L. (1993) Extracellular signals and reversible protein phosphorylation: what to Mek of it all. Cell 74, 215-217.
    • (1993) Cell , vol.74 , pp. 215-217
    • Crews, C.M.1    Erikson, R.L.2
  • 13
    • 0028850452 scopus 로고
    • Wortmannin and its structural analog demethoxyviridin inhibit stimulated phospholipase A(2) activity in Swiss 3T3 cells - Wortmannin is not a specific inhibitor of phosphatidylinositol 3-kinase
    • Cross M. J., Stewart A., Hodgkin M. N., Kerr D. J., and Wakelam M. J. O. (1995) Wortmannin and its structural analog demethoxyviridin inhibit stimulated phospholipase A(2) activity in Swiss 3T3 cells - wortmannin is not a specific inhibitor of phosphatidylinositol 3-kinase. J. Biol. Chem. 270, 25352-25355.
    • (1995) J. Biol. Chem. , vol.270 , pp. 25352-25355
    • Cross, M.J.1    Stewart, A.2    Hodgkin, M.N.3    Kerr, D.J.4    Wakelam, M.J.O.5
  • 14
    • 0028228616 scopus 로고
    • Activation of MAP kinase kinase is necessary and sufficient for PC 12 differentiation and transformation of NIH 3T3 cells
    • Crowley S., Paterson H., and Marshall C. J. (1994) Activation of MAP kinase kinase is necessary and sufficient for PC 12 differentiation and transformation of NIH 3T3 cells. Cell 77, 841-852.
    • (1994) Cell , vol.77 , pp. 841-852
    • Crowley, S.1    Paterson, H.2    Marshall, C.J.3
  • 15
    • 0029973651 scopus 로고    scopus 로고
    • Studies of partially transforming polyomavirus mutants establish a role for phosphatidylinositol 3-kinase in activation of pp70 S6 kinase
    • Dahl J., Freund R., Blenis J., and Benjamin T. L. (1996) Studies of partially transforming polyomavirus mutants establish a role for phosphatidylinositol 3-kinase in activation of pp70 S6 kinase. Mol. Cell. Biol. 16, 2728-2735.
    • (1996) Mol. Cell. Biol. , vol.16 , pp. 2728-2735
    • Dahl, J.1    Freund, R.2    Blenis, J.3    Benjamin, T.L.4
  • 16
    • 0030013407 scopus 로고    scopus 로고
    • Both rapamycin-sensitive and -insensitive pathways are involved in the phosphorylation of the initiation factor 4E binding protein (4E-BP1) in response to insulin in rat epididymal fat cells
    • Diggle T. A., Moule S. K., Avison M. B., Flynn A., Foulstone E. J., Proud C. G., and Demon R. M. (1996) Both rapamycin-sensitive and -insensitive pathways are involved in the phosphorylation of the initiation factor 4E binding protein (4E-BP1) in response to insulin in rat epididymal fat cells. Biochem. J. 316, 447-453.
    • (1996) Biochem. J. , vol.316 , pp. 447-453
    • Diggle, T.A.1    Moule, S.K.2    Avison, M.B.3    Flynn, A.4    Foulstone, E.J.5    Proud, C.G.6    Demon, R.M.7
  • 17
    • 0029907265 scopus 로고    scopus 로고
    • A role for Pyk2 and Src in linking G-protein-receptors with MAP kinase activation
    • Dikic I., Tokiwa G., Lev S., Courtneidge S. A., and Schlessinger J. (1996) A role for Pyk2 and Src in linking G-protein-receptors with MAP kinase activation. Nature 383, 547-550.
    • (1996) Nature , vol.383 , pp. 547-550
    • Dikic, I.1    Tokiwa, G.2    Lev, S.3    Courtneidge, S.A.4    Schlessinger, J.5
  • 18
    • 0028176297 scopus 로고
    • cAMP and β,γ subunits of heterotrimeric G proteins stimulate the mitogen-activated protein kinase pathway in COS-7 cells
    • Faure M., Voyno-Yasenetskaya T. A., and Bourne H. R. (1994) cAMP and β,γ subunits of heterotrimeric G proteins stimulate the mitogen-activated protein kinase pathway in COS-7 cells. J. Biol. Chem. 269, 7851-7854.
    • (1994) J. Biol. Chem. , vol.269 , pp. 7851-7854
    • Faure, M.1    Voyno-Yasenetskaya, T.A.2    Bourne, H.R.3
  • 20
    • 0029904963 scopus 로고    scopus 로고
    • Ras-dependent activation of fibroblast mitogen-activated protein kinase by 5HT1A receptor via G-protein β-γ subunit initiated pathway
    • Garnovskaya M. N., van Biesen T., Hawes B., Casamar Ramos S., Lefkowitz R. J., and Raymond J. R. (1996) Ras-dependent activation of fibroblast mitogen-activated protein kinase by 5HT1A receptor via G-protein β-γ subunit initiated pathway. Biochemistry 35, 13716-13722.
    • (1996) Biochemistry , vol.35 , pp. 13716-13722
    • Garnovskaya, M.N.1    Van Biesen, T.2    Hawes, B.3    Casamar Ramos, S.4    Lefkowitz, R.J.5    Raymond, J.R.6
  • 21
    • 0030912961 scopus 로고    scopus 로고
    • Evidence that antipsychotic drugs are inverse agonists at D2 dopamine receptors
    • Hall D. A. and Strange P. G. (1997) Evidence that antipsychotic drugs are inverse agonists at D2 dopamine receptors. Br. J. Pharmacol. 121, 731-736.
    • (1997) Br. J. Pharmacol. , vol.121 , pp. 731-736
    • Hall, D.A.1    Strange, P.G.2
  • 24
    • 0028936254 scopus 로고
    • Platelet-derived growth factor and angiotensin II stimulate the mitogen-activated protein kinase cascade in renal mesangial cells: Comparison of hypertrophic and hyperplastic agonists
    • Huwiler A., Stabel S., Fabbro D., and Pfeilschifter J. (1995) Platelet-derived growth factor and angiotensin II stimulate the mitogen-activated protein kinase cascade in renal mesangial cells: comparison of hypertrophic and hyperplastic agonists. J. Biochem. 305, 777-784.
    • (1995) J. Biochem. , vol.305 , pp. 777-784
    • Huwiler, A.1    Stabel, S.2    Fabbro, D.3    Pfeilschifter, J.4
  • 25
    • 0028800305 scopus 로고
    • Activation of Rac1, RhoA and mitogen-activated kinases is required for ras transformation
    • Khosravi-Far R., Solski P. A., Clark G. J., Kinch M. S., and Der C. J. (1995) Activation of Rac1, RhoA and mitogen-activated kinases is required for ras transformation. Mol. Cell. Biol. 15, 6443-6453.
    • (1995) Mol. Cell. Biol. , vol.15 , pp. 6443-6453
    • Khosravi-Far, R.1    Solski, P.A.2    Clark, G.J.3    Kinch, M.S.4    Der, C.J.5
  • 28
    • 0025979335 scopus 로고
    • Raf-1 kinase is required for growth of induced NIH 3T3 cells
    • Kolch W. G., Heidecker G., Lloyd P., and Rapp U. R. (1991) Raf-1 kinase is required for growth of induced NIH 3T3 cells. Nature 349, 426-428.
    • (1991) Nature , vol.349 , pp. 426-428
    • Kolch, W.G.1    Heidecker, G.2    Lloyd, P.3    Rapp, U.R.4
  • 30
    • 0027723678 scopus 로고
    • D2 dopamine receptor stimulation of mitogenesis in transfected Chinese hamster ovary cells: Relationship to dopamine stimulation of tyrosine phosphorylations
    • Lajiness M. E., Chio C. L., and Huff R. M. (1993) D2 dopamine receptor stimulation of mitogenesis in transfected Chinese hamster ovary cells: relationship to dopamine stimulation of tyrosine phosphorylations. J. Pharmacol. Exp. Ther. 267, 1573-581.
    • (1993) J. Pharmacol. Exp. Ther. , vol.267 , pp. 1573-1581
    • Lajiness, M.E.1    Chio, C.L.2    Huff, R.M.3
  • 32
    • 0028872649 scopus 로고
    • Specificity of receptor tyrosine kinase signalling: Transient versus sustained extracellular signal regulated kinase activation
    • Marshall C. J. (1995) Specificity of receptor tyrosine kinase signalling: transient versus sustained extracellular signal regulated kinase activation. Cell 80, 179-185.
    • (1995) Cell , vol.80 , pp. 179-185
    • Marshall, C.J.1
  • 33
    • 0029026778 scopus 로고
    • A novel mitogen-activated protein kinase phosphatase - Structure, expression and regulation
    • Misra-Press A., Rim C. S., Yao H., Roberson M. S., and Stork P. J. S. (1995) A novel mitogen-activated protein kinase phosphatase - structure, expression and regulation. J. Biol. Chem. 270, 14587-14596.
    • (1995) J. Biol. Chem. , vol.270 , pp. 14587-14596
    • Misra-Press, A.1    Rim, C.S.2    Yao, H.3    Roberson, M.S.4    Stork, P.J.S.5
  • 35
    • 0028829053 scopus 로고
    • Multiple signalling pathways involved in the stimulation of fatty acid and glycogen synthesis by insulin in rat epididymal fat pads
    • Moule S. K., Edgell N. J., Welsh G. I., Diggle T. A., Foulstone E. J., Heesom K. J., Proud C. G., and Denton R. M. (1995) Multiple signalling pathways involved in the stimulation of fatty acid and glycogen synthesis by insulin in rat epididymal fat pads. Biochem. J. 311, 595-601.
    • (1995) Biochem. J. , vol.311 , pp. 595-601
    • Moule, S.K.1    Edgell, N.J.2    Welsh, G.I.3    Diggle, T.A.4    Foulstone, E.J.5    Heesom, K.J.6    Proud, C.G.7    Denton, R.M.8
  • 36
    • 16944366762 scopus 로고    scopus 로고
    • Regulation of protein kinase B and glycogen synthase kinase 3 by insulin and β-adrenergic agonists in rat epididymal fat cells. Activation of protein kinase B by wortmannin-sensitive and -insensitive mechanisms
    • Moule S. K., Welsh G. I., Foulstone E. J., Heesom K., Edgell N., Proud C. G., and Denton R. M. (1997) Regulation of protein kinase B and glycogen synthase kinase 3 by insulin and β-adrenergic agonists in rat epididymal fat cells. Activation of protein kinase B by wortmannin-sensitive and -insensitive mechanisms. J. Biol. Chem. 272, 7713-7719.
    • (1997) J. Biol. Chem. , vol.272 , pp. 7713-7719
    • Moule, S.K.1    Welsh, G.I.2    Foulstone, E.J.3    Heesom, K.4    Edgell, N.5    Proud, C.G.6    Denton, R.M.7
  • 38
    • 0029078130 scopus 로고
    • Selective inhibition of p70 S6 kinase activation by phosphatidylinositol 3-kinase inhibitors
    • Petritsch C., Woscholski R., Edelmann H. M. L., Parker P. J., and Ballou L. M. (1995) Selective inhibition of p70 S6 kinase activation by phosphatidylinositol 3-kinase inhibitors. Eur. J. Biochem. 230, 431-438.
    • (1995) Eur. J. Biochem. , vol.230 , pp. 431-438
    • Petritsch, C.1    Woscholski, R.2    Edelmann, H.M.L.3    Parker, P.J.4    Ballou, L.M.5
  • 39
    • 0029815654 scopus 로고    scopus 로고
    • Efficacy of agonist-stimulated MEK activation determines the susceptibility of mitogen activated protein (MAP) kinase to inhibition in rat aortic smooth muscle cells
    • Plevin R., Scott P. H., Robinson C. J. M., and Gould G. W. (1996) Efficacy of agonist-stimulated MEK activation determines the susceptibility of mitogen activated protein (MAP) kinase to inhibition in rat aortic smooth muscle cells. Biochem. J. 318, 657-663.
    • (1996) Biochem. J. , vol.318 , pp. 657-663
    • Plevin, R.1    Scott, P.H.2    Robinson, C.J.M.3    Gould, G.W.4
  • 40
    • 0029915031 scopus 로고    scopus 로고
    • p70 S6 kinase: An enigma with variations
    • Proud C. G. (1996) p70 S6 kinase: an enigma with variations. Trends Biochem. Sci. 21, 181-185.
    • (1996) Trends Biochem. Sci. , vol.21 , pp. 181-185
    • Proud, C.G.1
  • 41
    • 0028175455 scopus 로고
    • Nuclear localization of p85s6k: Functional requirement tor entry into S-phase
    • Reinhard C., Fernandez A., Lamb N. J. C., and Thomas G. (1994) Nuclear localization of p85s6k: functional requirement tor entry into S-phase. EMBO J. 13, 1557-1565.
    • (1994) EMBO J. , vol.13 , pp. 1557-1565
    • Reinhard, C.1    Fernandez, A.2    Lamb, N.J.C.3    Thomas, G.4
  • 43
  • 45
    • 0030002235 scopus 로고    scopus 로고
    • Phospholipase-D mediated transphosphatidylation as a possible new pathway of ethanol-metabolism in isolated rat pancreatic acini
    • Rvdzewska G., Jurkowska G., and Gabryelewicz A. (1996) Phospholipase-D mediated transphosphatidylation as a possible new pathway of ethanol-metabolism in isolated rat pancreatic acini. J. Physiol. Pharmacol. 47, 385-395.
    • (1996) J. Physiol. Pharmacol. , vol.47 , pp. 385-395
    • Rvdzewska, G.1    Jurkowska, G.2    Gabryelewicz, A.3
  • 46
    • 0030605396 scopus 로고
    • A heterotrimeric GTPase-regulated isoform of PI3K and the regulation of its potential effectors
    • Stephens L., Hawkins P. T., Eguinoa A., and Cooke F. (1994) A heterotrimeric GTPase-regulated isoform of PI3K and the regulation of its potential effectors. Philos. Trans. R. Soc. Lond. [Biol.] 351, 211-216.
    • (1994) Philos. Trans. R. Soc. Lond. [Biol.] , vol.351 , pp. 211-216
    • Stephens, L.1    Hawkins, P.T.2    Eguinoa, A.3    Cooke, F.4
  • 47
    • 0030799406 scopus 로고    scopus 로고
    • Overexpression of wild type p70 S6 kinase interferes with cytokinesis
    • Sugiyama H., Papst P., Fujita M., Gelfand E. W., and Terada N. (1997) Overexpression of wild type p70 S6 kinase interferes with cytokinesis. Oncogene 15, 443-452.
    • (1997) Oncogene , vol.15 , pp. 443-452
    • Sugiyama, H.1    Papst, P.2    Fujita, M.3    Gelfand, E.W.4    Terada, N.5
  • 48
    • 0027358722 scopus 로고
    • MKP-1 (3CH134), an immediate early gene product, is a dual specificity phosphatase that dephosphorylates MAP kinase in vivo
    • Sun H., Charles C. H., Lau L. F., and Tonks N. K. (1993) MKP-1 (3CH134), an immediate early gene product, is a dual specificity phosphatase that dephosphorylates MAP kinase in vivo. Cell 75, 487-493.
    • (1993) Cell , vol.75 , pp. 487-493
    • Sun, H.1    Charles, C.H.2    Lau, L.F.3    Tonks, N.K.4
  • 49
    • 0026662412 scopus 로고
    • Inhibition or down-regulation of protein kinase C attenuates late phase p70s6k activation induced by epidermal growth factor but not by platelet-derived growth factor or insulin
    • Susa M., Vulevic D., Lane H. A., and Thomas G. (1992) Inhibition or down-regulation of protein kinase C attenuates late phase p70s6k activation induced by epidermal growth factor but not by platelet-derived growth factor or insulin. J. Biol. Chem. 267, 6905-6909.
    • (1992) J. Biol. Chem. , vol.267 , pp. 6905-6909
    • Susa, M.1    Vulevic, D.2    Lane, H.A.3    Thomas, G.4
  • 51
    • 0026486878 scopus 로고
    • Sustained activation of the mitogen-actwated protein (MAP) kinase cascade may be required for differentiation of PC12 cells. Comparison of the effects of nerve growth factor and epidermal growth factor
    • Traverse S., Gomez N., Paterson H., Marshall C., and Cohen P. (1992) Sustained activation of the mitogen-actwated protein (MAP) kinase cascade may be required for differentiation of PC12 cells. Comparison of the effects of nerve growth factor and epidermal growth factor. Biochem. J. 288, 351-355.
    • (1992) Biochem. J. , vol.288 , pp. 351-355
    • Traverse, S.1    Gomez, N.2    Paterson, H.3    Marshall, C.4    Cohen, P.5
  • 52
    • 0029670821 scopus 로고    scopus 로고
    • Go-protein α-subunits activate mitogen-activated protein kinase via a novelprotein kinase C-dependent mechanism
    • van Biesen T., Hawes B. E., Raymond J. R., Luttrell L. M., Koch W. J., and Lefkowitz R. J. (1997) Go-protein α-subunits activate mitogen-activated protein kinase via a novelprotein kinase C-dependent mechanism. J. Biol. Chem. 271, 1266-1269.
    • (1997) J. Biol. Chem. , vol.271 , pp. 1266-1269
    • Van Biesen, T.1    Hawes, B.E.2    Raymond, J.R.3    Luttrell, L.M.4    Koch, W.J.5    Lefkowitz, R.J.6
  • 54
    • 0029892373 scopus 로고    scopus 로고
    • Tyrosine kinases in activation of the MAP kinase cascade by G-protein-coupled receptors
    • Wan Y., Kurosaki T., and Huang X. (1996) Tyrosine kinases in activation of the MAP kinase cascade by G-protein-coupled receptors. Nature 380, 541-544.
    • (1996) Nature , vol.380 , pp. 541-544
    • Wan, Y.1    Kurosaki, T.2    Huang, X.3
  • 55
    • 0027991899 scopus 로고
    • Wortmannin inhibits the effects of insulin and serum on the activities of glycogen synthase kinase-3 and mitogen-activated protein kinase
    • Welsh G. I., Foulstone E. J., Young S. W., Tavaré J. M., and Proud C. G. (1994) Wortmannin inhibits the effects of insulin and serum on the activities of glycogen synthase kinase-3 and mitogen-activated protein kinase. Biochem. J. 303, 15-20.
    • (1994) Biochem. J. , vol.303 , pp. 15-20
    • Welsh, G.I.1    Foulstone, E.J.2    Young, S.W.3    Tavaré, J.M.4    Proud, C.G.5
  • 56
    • 0028939115 scopus 로고
    • Multiple independent inputs are required for activation of the p70 S6 kinase
    • Weng Q.-P., Andrabi K., Kozlowski M. T., Grove J. R., and Avruch J. (1995a) Multiple independent inputs are required for activation of the p70 S6 kinase. Mol. Cell. Biol. 15, 2333-2340.
    • (1995) Mol. Cell. Biol. , vol.15 , pp. 2333-2340
    • Weng, Q.-P.1    Andrabi, K.2    Kozlowski, M.T.3    Grove, J.R.4    Avruch, J.5
  • 57
    • 0028999052 scopus 로고
    • Phosphatidylinositol 3-kinase signals activation of p70 S6 kinase in situ through site-specific p70 phosphorylation
    • Weng Q. P., Andrabi, K., Klippel A., Kozlowski M. T. Williams L. T., and Avruch J. (1995b) Phosphatidylinositol 3-kinase signals activation of p70 S6 kinase in situ through site-specific p70 phosphorylation. Proc. Natl. Acad. Sci. USA 92, 5744-5748.
    • (1995) Proc. Natl. Acad. Sci. USA , vol.92 , pp. 5744-5748
    • Weng, Q.P.1    Andrabi, K.2    Klippel, A.3    Kozlowski, M.T.4    Williams, L.T.5    Avruch, J.6
  • 59
    • 0027954670 scopus 로고
    • Differentiation of PC12 cells in response to a cAMP analogue is accompanied by a sustained activation of mitogen-activated protein kinase. Comparison with the effects of insulin, growth factors and phorbol esters
    • Young S. W., Dickens M., and Tavare J. M. (1994) Differentiation of PC12 cells in response to a cAMP analogue is accompanied by a sustained activation of mitogen-activated protein kinase. Comparison with the effects of insulin, growth factors and phorbol esters. FEBS Lett. 338, 212-216.
    • (1994) FEBS Lett. , vol.338 , pp. 212-216
    • Young, S.W.1    Dickens, M.2    Tavare, J.M.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.