-
1
-
-
0035884572
-
Aromatics at the murine nicotinic receptor agonist binding site: Mutational analysis of the αY93 and αW149 residues
-
Akk, G. 2001. Aromatics at the murine nicotinic receptor agonist binding site: mutational analysis of the αY93 and αW149 residues. J. Physiol. 535:729-740.
-
(2001)
J. Physiol
, vol.535
, pp. 729-740
-
-
Akk, G.1
-
2
-
-
0030032121
-
Inorganic, monovalent cations compete with agonists for the transmitter binding site of nicotinic acetylcholine receptors
-
Akk, G., and A. Auerbach. 1996. Inorganic, monovalent cations compete with agonists for the transmitter binding site of nicotinic acetylcholine receptors. Biophys. J. 70:2652-2658.
-
(1996)
Biophys. J
, vol.70
, pp. 2652-2658
-
-
Akk, G.1
Auerbach, A.2
-
3
-
-
0029859799
-
Binding sites contribute unequally to the gating of mouse nicotinic αD200N acetylcholine receptors
-
Akk, G., S. Sine, and A. Auerbach. 1996. Binding sites contribute unequally to the gating of mouse nicotinic αD200N acetylcholine receptors. J. Physiol. 496:185-196.
-
(1996)
J. Physiol
, vol.496
, pp. 185-196
-
-
Akk, G.1
Sine, S.2
Auerbach, A.3
-
4
-
-
0032938313
-
A mutational analysis of the acetylcholine receptor channel transmitter binding site
-
Akk, G., M. Zhou, and A. Auerbach. 1999. A mutational analysis of the acetylcholine receptor channel transmitter binding site. Biophys. J. 76:207-218.
-
(1999)
Biophys. J
, vol.76
, pp. 207-218
-
-
Akk, G.1
Zhou, M.2
Auerbach, A.3
-
5
-
-
13444274310
-
Gating of acetylcholine receptor channels: Brownian motion across a broad transition state
-
Auerbach, A. 2005. Gating of acetylcholine receptor channels: Brownian motion across a broad transition state. Proc. Natl. Acad. Sci. USA. 102:1408-1412.
-
(2005)
Proc. Natl. Acad. Sci. USA
, vol.102
, pp. 1408-1412
-
-
Auerbach, A.1
-
6
-
-
36549084005
-
-
ow to turn the reaction coordinate into time
-
Auerbach, A. 2007. ?ow to turn the reaction coordinate into time. J. Gen. Physiol. 130:543-546.
-
(2007)
J. Gen. Physiol
, vol.130
, pp. 543-546
-
-
Auerbach, A.1
-
7
-
-
0035902009
-
Crystal structure of an ACh-binding protein reveals the ligand-binding domain of nicotinic receptors
-
Brejc, K. 2001. Crystal structure of an ACh-binding protein reveals the ligand-binding domain of nicotinic receptors. Nature. 411:269-276.
-
(2001)
Nature
, vol.411
, pp. 269-276
-
-
Brejc, K.1
-
8
-
-
1842475289
-
Nicotine and carbamylcholine binding to nicotinic acetylcholine = as studied in AChBP crystal structures
-
Celie, P.H., S.E. van Rossum-Fikkert, W.J. van Dijk, K. Brejc, A.B. Smit, and T.K. Sixma. 2004. Nicotine and carbamylcholine binding to nicotinic acetylcholine = as studied in AChBP crystal structures. Neuron. 41:907-914.
-
(2004)
Neuron
, vol.41
, pp. 907-914
-
-
Celie, P.H.1
van Rossum-Fikkert, S.E.2
van Dijk, W.J.3
Brejc, K.4
Smit, A.B.5
Sixma, T.K.6
-
9
-
-
11844258265
-
A speed limit for conformational change of an allosteric membrane protein
-
Chakrapani, S., and A. Auerbach. 2005. A speed limit for conformational change of an allosteric membrane protein. Proc. Natl. Acad. Sci. USA. 102:87-92.
-
(2005)
Proc. Natl. Acad. Sci. USA
, vol.102
, pp. 87-92
-
-
Chakrapani, S.1
Auerbach, A.2
-
10
-
-
0242583056
-
The role of loop 5 in acetylcholine receptor channel gating
-
Chakrapani, S., T.D. Bailey, and A. Auerbach. 2003. The role of loop 5 in acetylcholine receptor channel gating. J. Gen. Physiol. 122:521-539.
-
(2003)
J. Gen. Physiol
, vol.122
, pp. 521-539
-
-
Chakrapani, S.1
Bailey, T.D.2
Auerbach, A.3
-
11
-
-
1842686239
-
Gating dynamics of the acetylcholine receptor extracellular domain
-
Chakrapani, S., T.D. Bailey, and A. Auerbach. 2004. Gating dynamics of the acetylcholine receptor extracellular domain. J. Gen. Physiol. 123:341-356.
-
(2004)
J. Gen. Physiol
, vol.123
, pp. 341-356
-
-
Chakrapani, S.1
Bailey, T.D.2
Auerbach, A.3
-
12
-
-
0029153305
-
Activation kinetics of recombinant mouse nicotinic acetylcholine receptors: Mutations of α-subunit tyrosine 190 affect both binding and gating
-
Chen, J., Y. Zhang, G. Akk, S. Sine, and A. Auerbach. 1995. Activation kinetics of recombinant mouse nicotinic acetylcholine receptors: mutations of α-subunit tyrosine 190 affect both binding and gating. Biophys. J. 69:849-859.
-
(1995)
Biophys. J
, vol.69
, pp. 849-859
-
-
Chen, J.1
Zhang, Y.2
Akk, G.3
Sine, S.4
Auerbach, A.5
-
14
-
-
34547520128
-
Crystal structure of the extracellular domain of nAChR α1 bound to α-bungarotoxin at 1.94 Å resolution
-
Dellisanti, C.D., Y. Yao, J.C. Stroud, Z.Z. Wang, and L. Chen. 2007. Crystal structure of the extracellular domain of nAChR α1 bound to α-bungarotoxin at 1.94 Å resolution. Nat. Neurosci. 10:953-962.
-
(2007)
Nat. Neurosci
, vol.10
, pp. 953-962
-
-
Dellisanti, C.D.1
Yao, Y.2
Stroud, J.C.3
Wang, Z.Z.4
Chen, L.5
-
15
-
-
0034677524
-
Mapping the conformational wave of acetylcholine receptor channel gating
-
Grosman, C., M. Zhou, and A. Auerbach. 2000. Mapping the conformational wave of acetylcholine receptor channel gating. Nature. 403:773-776.
-
(2000)
Nature
, vol.403
, pp. 773-776
-
-
Grosman, C.1
Zhou, M.2
Auerbach, A.3
-
16
-
-
27144473613
-
Structures of Aplysia AChBP complexes with nicotinic agonists and antagonists reveal distinctive binding interfaces and conformations
-
Hansen, S.B., G. Sulzenbacher, T. Huxford, P. Marchot, P. Taylor, and Y. Bourne. 2005. Structures of Aplysia AChBP complexes with nicotinic agonists and antagonists reveal distinctive binding interfaces and conformations. EMBO J. 24:3635-3646.
-
(2005)
EMBO J
, vol.24
, pp. 3635-3646
-
-
Hansen, S.B.1
Sulzenbacher, G.2
Huxford, T.3
Marchot, P.4
Taylor, P.5
Bourne, Y.6
-
17
-
-
36549043834
-
Acetylcholine receptor channel gating at extracellular transmembrane domain interface: The cys-loop and M2-M3 linker
-
Jha, A., D. Cadugan, P. Purohit, and A. Auerbach. 2007. Acetylcholine receptor channel gating at extracellular transmembrane domain interface: the cys-loop and M2-M3 linker. J. Gen. Physiol. 130:547-558.
-
(2007)
J. Gen. Physiol
, vol.130
, pp. 547-558
-
-
Jha, A.1
Cadugan, D.2
Purohit, P.3
Auerbach, A.4
-
18
-
-
27744438169
-
Principal pathway coupling agonist binding to channel gating in nicotinic receptors
-
Lee, W.Y., and S.M. Sine. 2005. Principal pathway coupling agonist binding to channel gating in nicotinic receptors. Nature. 438:243-247.
-
(2005)
Nature
, vol.438
, pp. 243-247
-
-
Lee, W.Y.1
Sine, S.M.2
-
19
-
-
34247536305
-
Agonist-driven conformational changes in the inner β-sheet of α7 nicotinic receptors
-
McLaughlin, J.T., J. Fu, and R.L. Rosenberg. 2007. Agonist-driven conformational changes in the inner β-sheet of α7 nicotinic receptors. Mol. Pharmacol. 71:1312-1318.
-
(2007)
Mol. Pharmacol
, vol.71
, pp. 1312-1318
-
-
McLaughlin, J.T.1
Fu, J.2
Rosenberg, R.L.3
-
20
-
-
27244454364
-
Dynamics of the acetylcholine receptor pore at the gating transition state
-
Mitra, A., G.D. Cymes, and A. Auerbach. 2005. Dynamics of the acetylcholine receptor pore at the gating transition state. Proc. Natl. Acad. Sci. USA. 102:15069-15074.
-
(2005)
Proc. Natl. Acad. Sci. USA
, vol.102
, pp. 15069-15074
-
-
Mitra, A.1
Cymes, G.D.2
Auerbach, A.3
-
21
-
-
22244478670
-
Initial coupling of binding to gating mediated by conserved residues in the muscle nicotinic receptor
-
Mukhtasimova, N., C. Free, and S.M. Sine. 2005. Initial coupling of binding to gating mediated by conserved residues in the muscle nicotinic receptor. J. Gen. Physiol. 126:23-39.
-
(2005)
J. Gen. Physiol
, vol.126
, pp. 23-39
-
-
Mukhtasimova, N.1
Free, C.2
Sine, S.M.3
-
22
-
-
34247109679
-
An intersubunit trigger of channel gating in the muscle nicotinic receptor
-
Mukhtasimova, N., and S.M. Sine. 2007. An intersubunit trigger of channel gating in the muscle nicotinic receptor. J. Neurosci. 27:4110-4119.
-
(2007)
J. Neurosci
, vol.27
, pp. 4110-4119
-
-
Mukhtasimova, N.1
Sine, S.M.2
-
23
-
-
15844429136
-
Congenital myasthenic syndrome caused by decreased agonist binding affinity due to a mutation in the acetylcholine receptor [var epsilon] subunit
-
Ohno, K., H.-L. Wang, M. Milone, N. Bren, J.M. Brengman, S. Nakano, P. Quiram, J.N. Pruitt, S.M. Sine, and A.G. Engel. 1996. Congenital myasthenic syndrome caused by decreased agonist binding affinity due to a mutation in the acetylcholine receptor [var epsilon] subunit. Neuron. 17:157-170.
-
(1996)
Neuron
, vol.17
, pp. 157-170
-
-
Ohno, K.1
Wang, H.-L.2
Milone, M.3
Bren, N.4
Brengman, J.M.5
Nakano, S.6
Quiram, P.7
Pruitt, J.N.8
Sine, S.M.9
Engel, A.G.10
-
24
-
-
36549039473
-
Acetylcholine receptor gating at extracellular-transmembrane domain interface: The "pre-M1" linker
-
Purohit, P., and A. Auerbach. 2007. Acetylcholine receptor gating at extracellular-transmembrane domain interface: the "pre-M1" linker. J. Gen. Physiol. 130:559-568.
-
(2007)
J. Gen. Physiol
, vol.130
, pp. 559-568
-
-
Purohit, P.1
Auerbach, A.2
-
25
-
-
0030956174
-
Maximum likelihood estimation of aggregated Markov processes
-
Qin, F., A. Auerbach, and F. Sachs. 1997. Maximum likelihood estimation of aggregated Markov processes. Proc. Biol. Sci. 264:375-383.
-
(1997)
Proc. Biol. Sci
, vol.264
, pp. 375-383
-
-
Qin, F.1
Auerbach, A.2
Sachs, F.3
-
26
-
-
13444271681
-
Refined structure of the nicotinic acetylcholine receptor at 4 Å resolution
-
Unwin, N. 2005. Refined structure of the nicotinic acetylcholine receptor at 4 Å resolution. J. Mol. Biol. 346:967-989.
-
(2005)
J. Mol. Biol
, vol.346
, pp. 967-989
-
-
Unwin, N.1
-
27
-
-
0036304564
-
Activation of the nicotinic acetylcholine receptor involves a switch in conformation of the α subunits
-
Unwin, N., A. Miyazawa, J. Li, and Y. Fujiyoshi. 2002. Activation of the nicotinic acetylcholine receptor involves a switch in conformation of the α subunits. J. Mol. Biol. 319:1165-1176.
-
(2002)
J. Mol. Biol
, vol.319
, pp. 1165-1176
-
-
Unwin, N.1
Miyazawa, A.2
Li, J.3
Fujiyoshi, Y.4
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