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Volumn 1117, Issue , 2007, Pages 283-297

Rationale for using nitric oxide donor therapy for prevention of bone loss and treatment of osteoporosis in humans

Author keywords

cGMP; Estrogen; Menopause; Nitric oxide synthase inhibitors; Nitroglycerine; Novel therapies; OPG; Osteopenia; RANKL; SERM

Indexed keywords

BISPHOSPHONIC ACID DERIVATIVE; BONE MORPHOGENETIC PROTEIN 2; CALCITONIN; CALCIUM; CONJUGATED ESTROGEN; CYCLIC GMP; ESTRADIOL; ESTROGEN; FLUORIDE; GLYCERYL TRINITRATE; HORMONE; NITRATE; NITRIC OXIDE; NITRIC OXIDE DONOR; NITRIC OXIDE SYNTHASE INHIBITOR; OSTEOCLAST DIFFERENTIATION FACTOR; PLACEBO; RALOXIFENE; RHO GUANINE NUCLEOTIDE BINDING PROTEIN; SELECTIVE ESTROGEN RECEPTOR MODULATOR; TRANSCRIPTION FACTOR RUNX2; TRIAMCINOLONE ACETONIDE; VITAMIN D;

EID: 36549054084     PISSN: 00778923     EISSN: 17496632     Source Type: Book Series    
DOI: 10.1196/annals.1402.066     Document Type: Conference Paper
Times cited : (58)

References (50)
  • 1
    • 0025883342 scopus 로고
    • Nitric oxide: Physiology, pathophysiology and pharmacology
    • MONCADA, S., R.M.J. PALMER & C.A. HIGGS. 1991. Nitric oxide: physiology, pathophysiology and pharmacology. Pharmacol. Rev. 43: 109-142.
    • (1991) Pharmacol. Rev , vol.43 , pp. 109-142
    • MONCADA, S.1    PALMER, R.M.J.2    HIGGS, C.A.3
  • 2
    • 0023505509 scopus 로고
    • Endothelium-derived relaxing factor produced and released from artery and vein is nitric oxide
    • IGNARRO, L.J., G.M. BUGA, K.S. WOOD, et al. 1987. Endothelium-derived relaxing factor produced and released from artery and vein is nitric oxide. Proc. Natl. Acad. Sci. USA 84: 9265-9269.
    • (1987) Proc. Natl. Acad. Sci. USA , vol.84 , pp. 9265-9269
    • IGNARRO, L.J.1    BUGA, G.M.2    WOOD, K.S.3
  • 3
    • 0027752805 scopus 로고    scopus 로고
    • The L-arginine: Nitric oxide pathway
    • MONCADA, S. & C.A. HIGGS. The L-arginine: nitric oxide pathway. N. Engl. J. Med. 329: 2002-2012.
    • N. Engl. J. Med , vol.329
    • MONCADA, S.1    HIGGS, C.A.2
  • 4
    • 0032751981 scopus 로고    scopus 로고
    • Nitric oxide and cellular respiration
    • BRUNORI, M., A. GIUFFRE, P. SARTI, et al. 1999. Nitric oxide and cellular respiration. Cell Mol. Life Sci. 56: 549-557.
    • (1999) Cell Mol. Life Sci , vol.56 , pp. 549-557
    • BRUNORI, M.1    GIUFFRE, A.2    SARTI, P.3
  • 5
    • 0028000678 scopus 로고
    • Circulating nitrite/nitrate levels increases with follicular development: Indirect evidence for estradiol-mediated NO release
    • ROSSELLI, M., B. IMTHURN, P.J. KELLER, et al. 1994. Circulating nitrite/nitrate levels increases with follicular development: indirect evidence for estradiol-mediated NO release. Biochem. Biophys. Res. Commun. 202: 1543-1552.
    • (1994) Biochem. Biophys. Res. Commun , vol.202 , pp. 1543-1552
    • ROSSELLI, M.1    IMTHURN, B.2    KELLER, P.J.3
  • 6
    • 0031797335 scopus 로고    scopus 로고
    • Decreased nitric oxide levels and bone turnover in amenorrheic athletes with spinal osteopenia
    • STACY, E., P. KORKIA, M.V.J. HUKKANEN, et al. 1998. Decreased nitric oxide levels and bone turnover in amenorrheic athletes with spinal osteopenia. J. Clin. Endocrinol. Metab. 83: 3056-3061.
    • (1998) J. Clin. Endocrinol. Metab , vol.83 , pp. 3056-3061
    • STACY, E.1    KORKIA, P.2    HUKKANEN, M.V.J.3
  • 7
    • 0028907376 scopus 로고
    • Circulating nitric oxide (nitrite/ nitrate) levels in postmenopausal women substituted with 17B-estradiol and norethisterone acetate
    • ROSSELLI, M., B. IMTHURN, P.J. KELLER, et al. 1995. Circulating nitric oxide (nitrite/ nitrate) levels in postmenopausal women substituted with 17B-estradiol and norethisterone acetate. Hypertension 25: 848-853.
    • (1995) Hypertension , vol.25 , pp. 848-853
    • ROSSELLI, M.1    IMTHURN, B.2    KELLER, P.J.3
  • 8
    • 0029921126 scopus 로고    scopus 로고
    • Nitric oxide donor alleviates ovariectomy-induced bone loss
    • WIMALAWANSA, S.J., G. DEMARCO, P. GANGULA & C. YALLAMPALLI. 1996. Nitric oxide donor alleviates ovariectomy-induced bone loss. Bone 18: 301-304.
    • (1996) Bone , vol.18 , pp. 301-304
    • WIMALAWANSA, S.J.1    DEMARCO, G.2    GANGULA, P.3    YALLAMPALLI, C.4
  • 9
    • 0036798987 scopus 로고    scopus 로고
    • Obesity, body size, and risk of postmenopausal breast cancer: The Women's Health Initiative
    • MORIMOTO, L.M., E. WHITE, Z. CHEN, et al. 2002. Obesity, body size, and risk of postmenopausal breast cancer: The Women's Health Initiative. Cancer Causes Control 13: 741-751.
    • (2002) Cancer Causes Control , vol.13 , pp. 741-751
    • MORIMOTO, L.M.1    WHITE, E.2    CHEN, Z.3
  • 10
    • 33847110738 scopus 로고    scopus 로고
    • Calcium/vitamin d supplementation and cardiovascular events
    • For the Women's Health Initiative Investigators
    • HSIA, J., G. HEISS, H. REN, et al., For the Women's Health Initiative Investigators. 2007. Calcium/vitamin d supplementation and cardiovascular events. Circulation 115: 846-854.
    • (2007) Circulation , vol.115 , pp. 846-854
    • HSIA, J.1    HEISS, G.2    REN, H.3
  • 11
    • 0033783464 scopus 로고    scopus 로고
    • Nitroglycerine therapy is as effective as standard estrogen replacement therapy (premarin) in prevention of oophorectomy-induced bone loss: A human pilot clinical study
    • WIMALAWANSA, S.J. 2000. Nitroglycerine therapy is as effective as standard estrogen replacement therapy (premarin) in prevention of oophorectomy-induced bone loss: a human pilot clinical study. J. Bone Miner. Res. 15: 2240-2244.
    • (2000) J. Bone Miner. Res , vol.15 , pp. 2240-2244
    • WIMALAWANSA, S.J.1
  • 12
    • 36549081839 scopus 로고    scopus 로고
    • In vivo and in vitro effects of nitric oxide donor, nitroglycerine on bone. J. Musculoskeleta Interact
    • In press
    • WIMALAWANSA, S.J. In vivo and in vitro effects of nitric oxide donor, nitroglycerine on bone. J. Musculoskeleta Interact. (In press).
    • WIMALAWANSA, S.J.1
  • 13
    • 0000664911 scopus 로고    scopus 로고
    • Diagnosis, osteoporosis prevention, and therapy. JAMA
    • Consensus Development Conference
    • Consensus Development Conference. 2001. Diagnosis, osteoporosis prevention, and therapy. JAMA 285: 785-795.
    • (2001) , vol.285 , pp. 785-795
  • 14
    • 0033609408 scopus 로고    scopus 로고
    • Direct microsensor measurement of nitric oxide production by the osteoclast
    • SILVERTON, S.F., O.A. ADEBANJO, B.S. MOONGA, et al. 1999. Direct microsensor measurement of nitric oxide production by the osteoclast. Biochem. Biophys. Res. Commun. 259(1): 73-77.
    • (1999) Biochem. Biophys. Res. Commun , vol.259 , Issue.1 , pp. 73-77
    • SILVERTON, S.F.1    ADEBANJO, O.A.2    MOONGA, B.S.3
  • 15
    • 0028223282 scopus 로고
    • Potentiation of osteoclastic bone resorbing activity by inhibition of nitric oxide synthase
    • KASTEN, T.P., P. COLLIN-OSDOBY, N. PATEL, et al. 1994. Potentiation of osteoclastic bone resorbing activity by inhibition of nitric oxide synthase. Proc. Natl. Acad. Sci. USA 91: 3569-3573.
    • (1994) Proc. Natl. Acad. Sci. USA , vol.91 , pp. 3569-3573
    • KASTEN, T.P.1    COLLIN-OSDOBY, P.2    PATEL, N.3
  • 16
    • 0028294282 scopus 로고
    • Inducible production of nitric oxide in osteoblast-like cells and in fetal mouse bone explants is associated with suppression of osteoclastic bone resorption
    • LOWIK, C.W.G.M., P.H. NIBBERING, M. VAN DER RUIT & S.E. PAPAPOULOS. 1994. Inducible production of nitric oxide in osteoblast-like cells and in fetal mouse bone explants is associated with suppression of osteoclastic bone resorption. J. Clin. Invest. 93: 1465-1472.
    • (1994) J. Clin. Invest , vol.93 , pp. 1465-1472
    • LOWIK, C.W.G.M.1    NIBBERING, P.H.2    VAN DER RUIT, M.3    PAPAPOULOS, S.E.4
  • 17
    • 0031695361 scopus 로고    scopus 로고
    • Related articles, links. lipopolysaccharide (LPS) stimulates the production of tumor necrosis factor (TNF)-alpha and expression of inducible nitric oxide synthase (iNOS) by osteoclasts (OCL) in murine bone marrow cell culture
    • KIKKAWA, I., S. SAITO, K. TOMINAGA, et al. 1998. Related articles, links. lipopolysaccharide (LPS) stimulates the production of tumor necrosis factor (TNF)-alpha and expression of inducible nitric oxide synthase (iNOS) by osteoclasts (OCL) in murine bone marrow cell culture. Microbiol. Immunol. 42: 591-598.
    • (1998) Microbiol. Immunol , vol.42 , pp. 591-598
    • KIKKAWA, I.1    SAITO, S.2    TOMINAGA, K.3
  • 18
    • 0346459934 scopus 로고    scopus 로고
    • The influence of nitric oxide synthase inhibitor L-NAME on bones of male rats with streptozotocin-induced diabetes
    • BROULIK, P.D., M. HALUZIK & J. SKRHA. 2003. The influence of nitric oxide synthase inhibitor L-NAME on bones of male rats with streptozotocin-induced diabetes. Physiol. Res. 52: 729-734.
    • (2003) Physiol. Res , vol.52 , pp. 729-734
    • BROULIK, P.D.1    HALUZIK, M.2    SKRHA, J.3
  • 19
    • 0028261047 scopus 로고
    • Human osteoblast-like cells produce nitric oxide and express inducible nitric oxide synthase
    • RALSTON, S.H., D. TODD, M.H. HELFRICH, et al. 1994. Human osteoblast-like cells produce nitric oxide and express inducible nitric oxide synthase. Endocrinology 135: 330-336.
    • (1994) Endocrinology , vol.135 , pp. 330-336
    • RALSTON, S.H.1    TODD, D.2    HELFRICH, M.H.3
  • 20
    • 0028793469 scopus 로고
    • Cytokine-stimulated expression of nitric oxide synthase by mouse, rat and human osteoblast-like cells and its functional role in osteoblast metabolism
    • HUKKANEN, M., F.J. HUGHES, L.D.K. BUTTERY, et al. 1995. Cytokine-stimulated expression of nitric oxide synthase by mouse, rat and human osteoblast-like cells and its functional role in osteoblast metabolism. Endocrinology 136: 5445-5453.
    • (1995) Endocrinology , vol.136 , pp. 5445-5453
    • HUKKANEN, M.1    HUGHES, F.J.2    BUTTERY, L.D.K.3
  • 21
    • 0030780215 scopus 로고    scopus 로고
    • Inflammation and bone metabolism in rheumatoid arthritis. Patho-genetic viewpoints and therapeutic possibilities [Review]
    • OELZNER, P. & G. HEIN. 1997. Inflammation and bone metabolism in rheumatoid arthritis. Patho-genetic viewpoints and therapeutic possibilities [Review]. Medizinische Klinik 92: 607-614.
    • (1997) Medizinische Klinik , vol.92 , pp. 607-614
    • OELZNER, P.1    HEIN, G.2
  • 22
    • 0025872336 scopus 로고
    • Osteoclast inhibition: An action of nitric oxide not mediated by cyclic GMP
    • MACINTYRE I., M. ZAIDI, A.A.S.M. TOWHIDUL, et al. 1991. Osteoclast inhibition: an action of nitric oxide not mediated by cyclic GMP. Proc. Natl. Acad. Sci. USA 88: 2936-2940.
    • (1991) Proc. Natl. Acad. Sci. USA , vol.88 , pp. 2936-2940
    • MACINTYRE, I.1    ZAIDI, M.2    TOWHIDUL, A.A.S.M.3
  • 23
    • 0033392377 scopus 로고    scopus 로고
    • Evidence for a pathogenic role of nitric oxide in inflammation-induced osteoporosis
    • ARMOUR, K.E., R.J. VAN'T HOF, P.S. GRABOWSKI, et al. 1999. Evidence for a pathogenic role of nitric oxide in inflammation-induced osteoporosis. J. Bone Miner. Res. 14: 2137-2142.
    • (1999) J. Bone Miner. Res , vol.14 , pp. 2137-2142
    • ARMOUR, K.E.1    VAN'T HOF, R.J.2    GRABOWSKI, P.S.3
  • 24
    • 0034931341 scopus 로고    scopus 로고
    • Nitric oxide and bone [Review]
    • VAN'T HOF, R.J. & S.H. RALSTON. 2001. Nitric oxide and bone [Review]. Immunology 103: 255-261.
    • (2001) Immunology , vol.103 , pp. 255-261
    • VAN'T HOF, R.J.1    RALSTON, S.H.2
  • 25
    • 0035024965 scopus 로고    scopus 로고
    • Effect of L-lysine and L-arginine on primary osteoblast cultures from normal and osteopenic rats
    • FINI, M., P. TORRICELLI, G. GIAVARESI, et al. 2001. Effect of L-lysine and L-arginine on primary osteoblast cultures from normal and osteopenic rats. Biomed. Pharmacother. 55: 213-220.
    • (2001) Biomed. Pharmacother , vol.55 , pp. 213-220
    • FINI, M.1    TORRICELLI, P.2    GIAVARESI, G.3
  • 26
    • 0035139484 scopus 로고    scopus 로고
    • Endothelial nitric oxide synthase gene-deficient mice demonstrate marked retardation in postnatal bone formation, reduced bone volume, and defects in osteoblast maturation and activity
    • AGUIRRE, J., L. BUTTERY, M. O'SHAUGHNESSY, et al. 2001. Endothelial nitric oxide synthase gene-deficient mice demonstrate marked retardation in postnatal bone formation, reduced bone volume, and defects in osteoblast maturation and activity. Am. J. Pathol. 158: 247-257.
    • (2001) Am. J. Pathol , vol.158 , pp. 247-257
    • AGUIRRE, J.1    BUTTERY, L.2    O'SHAUGHNESSY, M.3
  • 27
    • 0029564705 scopus 로고
    • Mechanical strain-induced NO production by bone cells: A possible role in adaptive bone (re)modeling
    • PITSILLIDES, A.A., S.C.F. RAWLINSON, R.F.L. SUSWULLO, et al. 1995. Mechanical strain-induced NO production by bone cells: a possible role in adaptive bone (re)modeling. FASEB J. 9: 1614-1622.
    • (1995) FASEB J , vol.9 , pp. 1614-1622
    • PITSILLIDES, A.A.1    RAWLINSON, S.C.F.2    SUSWULLO, R.F.L.3
  • 28
    • 0029940159 scopus 로고    scopus 로고
    • Nitric oxide inhibitor L-NAME suppresses mechanically induced bone formation in rats
    • TURNER, C.H., Y. TAKANO, I OWAN & G.A. MURRELL. 1996. Nitric oxide inhibitor L-NAME suppresses mechanically induced bone formation in rats. Am. J. Physiol. 270: E634-E639.
    • (1996) Am. J. Physiol , vol.270
    • TURNER, C.H.1    TAKANO, Y.2    OWAN, I.3    MURRELL, G.A.4
  • 29
    • 0034039284 scopus 로고    scopus 로고
    • Frequency-dependent effect of nitric oxide donor nitroglycerine on bone
    • WIMALAWANSA, S.M., T. CHAPPA, L. FANG, et al. 2000. Frequency-dependent effect of nitric oxide donor nitroglycerine on bone. J. Bone. Miner. Res. 15: 1119-1125.
    • (2000) J. Bone. Miner. Res , vol.15 , pp. 1119-1125
    • WIMALAWANSA, S.M.1    CHAPPA, T.2    FANG, L.3
  • 30
    • 0033405866 scopus 로고    scopus 로고
    • Restoration of ovariectomy-induced bone loss by nitroglycerine
    • WIMALAWANSA, S.J. 2000. Restoration of ovariectomy-induced bone loss by nitroglycerine. Calcif. Tiss. Int. 66: 56-60.
    • (2000) Calcif. Tiss. Int , vol.66 , pp. 56-60
    • WIMALAWANSA, S.J.1
  • 31
    • 0030824397 scopus 로고    scopus 로고
    • Prevention of corticosteroid-induced bone loss with nitric oxide donor nitroglycerine in male rats
    • WIMALAWANSA, S.J., M.T. CHAPA, C. YALLAMPALLI, et al. 1997. Prevention of corticosteroid-induced bone loss with nitric oxide donor nitroglycerine in male rats. Bone 21: 275-280.
    • (1997) Bone , vol.21 , pp. 275-280
    • WIMALAWANSA, S.J.1    CHAPA, M.T.2    YALLAMPALLI, C.3
  • 32
    • 0035009914 scopus 로고    scopus 로고
    • GARRETT, I.R., G. GUTIERREZ & G.R. MUNDY. 2004. Statins and bone formation [Review]. Pharma. Design 7: 715-736.
    • GARRETT, I.R., G. GUTIERREZ & G.R. MUNDY. 2004. Statins and bone formation [Review]. Pharma. Design 7: 715-736.
  • 33
    • 0029766224 scopus 로고    scopus 로고
    • Bisphosphonates induce apoptosis in mouse macrophage-like cells in vitro by a nitric oxide-independent mechanism
    • ROGERS, M.J., K.M. CHILTON, F.P. COXON, et al. 1996. Bisphosphonates induce apoptosis in mouse macrophage-like cells in vitro by a nitric oxide-independent mechanism. J. Bone Miner. Res. 11: 1482-1491.
    • (1996) J. Bone Miner. Res , vol.11 , pp. 1482-1491
    • ROGERS, M.J.1    CHILTON, K.M.2    COXON, F.P.3
  • 34
    • 0031591593 scopus 로고    scopus 로고
    • New drugs with positive effects on bones [Review]
    • ZOFKOVA, I. & R.L. KANCEVA. 1997. New drugs with positive effects on bones [Review]. Casopis Lekaru Ceskych 136: 459-463.
    • (1997) Casopis Lekaru Ceskych , vol.136 , pp. 459-463
    • ZOFKOVA, I.1    KANCEVA, R.L.2
  • 35
    • 3242685946 scopus 로고    scopus 로고
    • Related articles, links. involvement of iNOS-dependent NO production in the stimulation of osteoclast survival by TNF-alpha
    • LEE, S.K., H. HUANG, S.W. LEE, et al. 2004. Related articles, links. involvement of iNOS-dependent NO production in the stimulation of osteoclast survival by TNF-alpha. Exp. Cell. Res. 298: 359-368.
    • (2004) Exp. Cell. Res , vol.298 , pp. 359-368
    • LEE, S.K.1    HUANG, H.2    LEE, S.W.3
  • 36
    • 0028928513 scopus 로고
    • Bidirectional regulation of osteoclast function by nitric oxide synthase isoforms
    • BRANDI, M.L., M. HUKKANEN, T. UMEDA, et al. 1995. Bidirectional regulation of osteoclast function by nitric oxide synthase isoforms. Proc. Natl. Acad. Sci. USA 92: 2954-2958.
    • (1995) Proc. Natl. Acad. Sci. USA , vol.92 , pp. 2954-2958
    • BRANDI, M.L.1    HUKKANEN, M.2    UMEDA, T.3
  • 37
    • 0031860349 scopus 로고    scopus 로고
    • Response of normal and osteoporotic human bone cells to mechanical stress in vitro
    • STERCK, J.G., J. KLEIN-NULEND, P. LIPS & E.H. BURGER. 1998. Response of normal and osteoporotic human bone cells to mechanical stress in vitro. Am. J. Physiol. 274: E1113-E1120.
    • (1998) Am. J. Physiol , vol.274
    • STERCK, J.G.1    KLEIN-NULEND, J.2    LIPS, P.3    BURGER, E.H.4
  • 38
    • 0342896840 scopus 로고    scopus 로고
    • The therapeutic use of nitrates does not influence postmenopausal osteoporosis
    • JAMAL, S., G. MILANI, R. LIPSCHUTZ, et al. 1997. The therapeutic use of nitrates does not influence postmenopausal osteoporosis. J. Bone. Miner. Res. 12(Suppl 1): S229.
    • (1997) J. Bone. Miner. Res , vol.12 , Issue.SUPPL. 1
    • JAMAL, S.1    MILANI, G.2    LIPSCHUTZ, R.3
  • 39
    • 0026775653 scopus 로고
    • Production of nitric oxide by murine bone marrow cells
    • PUNJABI, C.J., D.L. LASKIN, D.E. HECK & J.D. LASKIN. 1992. Production of nitric oxide by murine bone marrow cells. J. Immunol. 149: 2179-2184.
    • (1992) J. Immunol , vol.149 , pp. 2179-2184
    • PUNJABI, C.J.1    LASKIN, D.L.2    HECK, D.E.3    LASKIN, J.D.4
  • 40
    • 0033140245 scopus 로고    scopus 로고
    • Responses of bone cells to biomechanical forces in vitro [Review]
    • BURGER, E.H. & J. KLEIN-NULEN. 1999. Responses of bone cells to biomechanical forces in vitro [Review]. Adv. Dental Res. 13: 93-98.
    • (1999) Adv. Dental Res , vol.13 , pp. 93-98
    • BURGER, E.H.1    KLEIN-NULEN, J.2
  • 41
    • 0029868213 scopus 로고    scopus 로고
    • Nitric oxide and bone [Review]
    • EVANS, D.M. & S.H. RALSTON. 1996. Nitric oxide and bone [Review]. J. Bone Miner. Res. 11: 300-305.
    • (1996) J. Bone Miner. Res , vol.11 , pp. 300-305
    • EVANS, D.M.1    RALSTON, S.H.2
  • 42
    • 0007685353 scopus 로고
    • Nitric oxide stimulates mineralization in osteoblastic cell cultures
    • KAWASE, T., G.A. HOWARD, B.A. ROOS & D.M. BURNS. 1993. Nitric oxide stimulates mineralization in osteoblastic cell cultures. J. Bone Miner. Res. 8: S372.
    • (1993) J. Bone Miner. Res , vol.8
    • KAWASE, T.1    HOWARD, G.A.2    ROOS, B.A.3    BURNS, D.M.4
  • 43
    • 0028080207 scopus 로고
    • Aginine supplementation in the prevention and treatment of osteoporosis
    • VISSER, J.J. & K. EKMAN. 1994. Aginine supplementation in the prevention and treatment of osteoporosis. Med. Hypotheses. 43: 339-342.
    • (1994) Med. Hypotheses , vol.43 , pp. 339-342
    • VISSER, J.J.1    EKMAN, K.2
  • 44
    • 0035670577 scopus 로고    scopus 로고
    • Activation of the inducible nitric oxide synthase pathway contributes to inflammation-induced osteoporosis by suppressing bone formation and causing osteoblastapoptosis
    • ARMOUR, K.J., K.E. ARMOUR, R.J. VAN'T HOF, et al. 2001. Activation of the inducible nitric oxide synthase pathway contributes to inflammation-induced osteoporosis by suppressing bone formation and causing osteoblastapoptosis. Arthritis Rheumat. 44: 2790-2796.
    • (2001) Arthritis Rheumat , vol.44 , pp. 2790-2796
    • ARMOUR, K.J.1    ARMOUR, K.E.2    VAN'T HOF, R.J.3
  • 45
    • 0031732762 scopus 로고    scopus 로고
    • Estrogen up-regulates endothelial constitutive nitric oxide synthase expression in human osteoblast-like cells
    • ARMOUR, K.E. & S.H. RALSTON. 1998. Estrogen up-regulates endothelial constitutive nitric oxide synthase expression in human osteoblast-like cells. Endocrinology 139: 799-802.
    • (1998) Endocrinology , vol.139 , pp. 799-802
    • ARMOUR, K.E.1    RALSTON, S.H.2
  • 46
    • 36549066562 scopus 로고    scopus 로고
    • Nitric oxide: A new class of drugs for multiple disorders
    • in press
    • WIMALAWANSA, S.J. Nitric oxide: a new class of drugs for multiple disorders. Exp. Opin. Pharmacother. (in press).
    • Exp. Opin. Pharmacother
    • WIMALAWANSA, S.J.1
  • 47
    • 36549046459 scopus 로고    scopus 로고
    • GRIMES, J.P., A. WILSON, G. ROJO & S. WIMALAWANSA. 2005. Risk factors associated with low vitamin D levels in postmenopausal women. Baseline analysis of NOVEL clinical study. Natl. Osteoporos. Found. Ann. Meet. (Abst.)
    • GRIMES, J.P., A. WILSON, G. ROJO & S. WIMALAWANSA. 2005. Risk factors associated with low vitamin D levels in postmenopausal women. Baseline analysis of NOVEL clinical study. Natl. Osteoporos. Found. Ann. Meet. (Abst.)
  • 48
    • 36549006885 scopus 로고    scopus 로고
    • WIMALAWANSA, S.J., 1988. Ph.D. Thesis. Calcitonin gene-related peptide: isolation, distribution and receptor binding. University of London.
    • WIMALAWANSA, S.J., 1988. Ph.D. Thesis. Calcitonin gene-related peptide: isolation, distribution and receptor binding. University of London.
  • 49
    • 36549016992 scopus 로고    scopus 로고
    • Enhancement of bone mineral density with the combination of therapy with nitric oxide donors and bisphosphonates
    • In press
    • WIMALAWANSA, D.M., S.M. WIMALAWANSA, C. YALLAMPALLI & S.J. WIMALAWANSA. Enhancement of bone mineral density with the combination of therapy with nitric oxide donors and bisphosphonates. Calcif. Tiss. Int. (In press).
    • Calcif. Tiss. Int
    • WIMALAWANSA, D.M.1    WIMALAWANSA, S.M.2    YALLAMPALLI, C.3    WIMALAWANSA, S.J.4
  • 50
    • 13244267455 scopus 로고    scopus 로고
    • Osteoclast-derived activity in the coupling of bone formation to resorption
    • MARTIN, T.J., N.A. SIMS. 2005. Osteoclast-derived activity in the coupling of bone formation to resorption. Trends Mol. Med. 11: 76-81.
    • (2005) Trends Mol. Med , vol.11 , pp. 76-81
    • MARTIN, T.J.1    SIMS, N.A.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.