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Volumn 314, Issue 1, 2008, Pages 164-172

Giant mitochondria do not fuse and exchange their contents with normal mitochondria

Author keywords

Giant mitochondria; L6 rat myoblasts; Mitochondrial fusion proteins; Mitochondrial membrane potential; Mitofusin 2; OPA1

Indexed keywords

HYBRID PROTEIN; MITOFUSIN 2; OPA1 PROTEIN; UNCLASSIFIED DRUG;

EID: 36549002757     PISSN: 00144827     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.yexcr.2007.09.013     Document Type: Article
Times cited : (82)

References (36)
  • 1
    • 0036236006 scopus 로고    scopus 로고
    • The mitochondrial-lysosomal axis theory of aging: accumulation of damaged mitochondria as a result of imperfect autophagocytosis
    • Brunk U.T., and Terman A. The mitochondrial-lysosomal axis theory of aging: accumulation of damaged mitochondria as a result of imperfect autophagocytosis. Eur. J. Biochem. 269 (2002) 1996-2002
    • (2002) Eur. J. Biochem. , vol.269 , pp. 1996-2002
    • Brunk, U.T.1    Terman, A.2
  • 2
    • 0036236939 scopus 로고    scopus 로고
    • The reductive hotspot hypothesis of mammalian aging: membrane metabolism magnifies mutant mitochondrial mischief
    • de Grey A.D. The reductive hotspot hypothesis of mammalian aging: membrane metabolism magnifies mutant mitochondrial mischief. Eur. J. Biochem. 269 (2002) 2003-2009
    • (2002) Eur. J. Biochem. , vol.269 , pp. 2003-2009
    • de Grey, A.D.1
  • 3
    • 0023882449 scopus 로고
    • Age-related changes in the skeletal muscle cells
    • Beregi E., Regius O., Huttl T., and Gobl Z. Age-related changes in the skeletal muscle cells. Z. Gerontol. 21 (1988) 83-86
    • (1988) Z. Gerontol. , vol.21 , pp. 83-86
    • Beregi, E.1    Regius, O.2    Huttl, T.3    Gobl, Z.4
  • 4
    • 0023227618 scopus 로고
    • Giant mitochondria in the myocardium of aging and endurance-trained mice
    • Coleman R., Silbermann M., Gershon D., and Reznick A.Z. Giant mitochondria in the myocardium of aging and endurance-trained mice. Gerontology 33 (1987) 34-39
    • (1987) Gerontology , vol.33 , pp. 34-39
    • Coleman, R.1    Silbermann, M.2    Gershon, D.3    Reznick, A.Z.4
  • 6
    • 3242715838 scopus 로고    scopus 로고
    • Aging of cardiac myocytes in culture: oxidative stress, lipofuscin accumulation, and mitochondrial turnover
    • Terman A., Dalen H., Eaton J.W., Neuzil J., and Brunk U.T. Aging of cardiac myocytes in culture: oxidative stress, lipofuscin accumulation, and mitochondrial turnover. Ann. N.Y. Acad. Sci. 1019 (2004) 70-77
    • (2004) Ann. N.Y. Acad. Sci. , vol.1019 , pp. 70-77
    • Terman, A.1    Dalen, H.2    Eaton, J.W.3    Neuzil, J.4    Brunk, U.T.5
  • 7
    • 0016433778 scopus 로고
    • Chloramphenicol-induced giant hepatic mitochondria
    • Albring M., Radsak K., and Thoenes W. Chloramphenicol-induced giant hepatic mitochondria. Naturwissenschaften 62 (1975) 43-44
    • (1975) Naturwissenschaften , vol.62 , pp. 43-44
    • Albring, M.1    Radsak, K.2    Thoenes, W.3
  • 9
    • 0018865126 scopus 로고
    • Ultrastructural effects of riboflavin deficiency on rat hepatic mitochondria
    • Tandler B., and Hoppel C.L. Ultrastructural effects of riboflavin deficiency on rat hepatic mitochondria. Anat. Rec. 196 (1980) 183-190
    • (1980) Anat. Rec. , vol.196 , pp. 183-190
    • Tandler, B.1    Hoppel, C.L.2
  • 10
    • 0016144931 scopus 로고
    • Giant mitochondria in erythroleukaemia
    • Ghadially F.N., and Skinnider L.F. Giant mitochondria in erythroleukaemia. J. Pathol. 114 (1974) 113-117
    • (1974) J. Pathol. , vol.114 , pp. 113-117
    • Ghadially, F.N.1    Skinnider, L.F.2
  • 11
    • 12344251782 scopus 로고    scopus 로고
    • Inhibition of autophagy with 3-methyladenine results in impaired turnover of lysosomes and accumulation of lipofuscin-like material
    • Stroikin Y., Dalen H., Loof S., and Terman A. Inhibition of autophagy with 3-methyladenine results in impaired turnover of lysosomes and accumulation of lipofuscin-like material. Eur. J. Cell Biol. 83 (2004) 583-590
    • (2004) Eur. J. Cell Biol. , vol.83 , pp. 583-590
    • Stroikin, Y.1    Dalen, H.2    Loof, S.3    Terman, A.4
  • 12
    • 0042707790 scopus 로고    scopus 로고
    • Mitochondrial recycling and aging of cardiac myocytes: the role of autophagocytosis
    • Terman A., Dalen H., Eaton J.W., Neuzil J., and Brunk U.T. Mitochondrial recycling and aging of cardiac myocytes: the role of autophagocytosis. Exp. Gerontol. 38 (2003) 863-876
    • (2003) Exp. Gerontol. , vol.38 , pp. 863-876
    • Terman, A.1    Dalen, H.2    Eaton, J.W.3    Neuzil, J.4    Brunk, U.T.5
  • 13
    • 0033978633 scopus 로고    scopus 로고
    • Distinct classes of phosphatidylinositol 3′-kinases are involved in signaling pathways that control macroautophagy in HT-29 cells
    • Petiot A., Ogier-Denis E., Blommaart E.F., Meijer A.J., and Codogno P. Distinct classes of phosphatidylinositol 3′-kinases are involved in signaling pathways that control macroautophagy in HT-29 cells. J. Biol. Chem. 275 (2000) 992-998
    • (2000) J. Biol. Chem. , vol.275 , pp. 992-998
    • Petiot, A.1    Ogier-Denis, E.2    Blommaart, E.F.3    Meijer, A.J.4    Codogno, P.5
  • 14
    • 0023465842 scopus 로고
    • Comparative morphological study of age related mitochondrial changes of the lymphocytes and skeletal muscle cells
    • Beregi E., and Regius O. Comparative morphological study of age related mitochondrial changes of the lymphocytes and skeletal muscle cells. Acta Morphol. Hung. 35 (1987) 219-224
    • (1987) Acta Morphol. Hung. , vol.35 , pp. 219-224
    • Beregi, E.1    Regius, O.2
  • 15
    • 0019486026 scopus 로고
    • Mitochondrial alterations in the spinal ganglion neurons in ageing rats
    • Vanneste J., and van den Bosch de Aguilar P. Mitochondrial alterations in the spinal ganglion neurons in ageing rats. Acta Neuropathol. (Berl) 54 (1981) 83-87
    • (1981) Acta Neuropathol. (Berl) , vol.54 , pp. 83-87
    • Vanneste, J.1    van den Bosch de Aguilar, P.2
  • 17
    • 10644296253 scopus 로고    scopus 로고
    • Fzo1, a protein involved in mitochondrial fusion, inhibits apoptosis
    • Sugioka R., Shimizu S., and Tsujimoto Y. Fzo1, a protein involved in mitochondrial fusion, inhibits apoptosis. J. Biol. Chem. 279 (2004) 52726-52734
    • (2004) J. Biol. Chem. , vol.279 , pp. 52726-52734
    • Sugioka, R.1    Shimizu, S.2    Tsujimoto, Y.3
  • 19
    • 0036906665 scopus 로고    scopus 로고
    • Mitochondrial fusion in human cells is efficient, requires the inner membrane potential, and is mediated by mitofusins
    • Legros F., Lombes A., Frachon P., and Rojo M. Mitochondrial fusion in human cells is efficient, requires the inner membrane potential, and is mediated by mitofusins. Mol. Biol. Cell 13 (2002) 4343-4354
    • (2002) Mol. Biol. Cell , vol.13 , pp. 4343-4354
    • Legros, F.1    Lombes, A.2    Frachon, P.3    Rojo, M.4
  • 20
    • 22544451586 scopus 로고    scopus 로고
    • Disruption of fusion results in mitochondrial heterogeneity and dysfunction
    • Chen H., Chomyn A., and Chan D.C. Disruption of fusion results in mitochondrial heterogeneity and dysfunction. J. Biol. Chem. 280 (2005) 26185-26192
    • (2005) J. Biol. Chem. , vol.280 , pp. 26185-26192
    • Chen, H.1    Chomyn, A.2    Chan, D.C.3
  • 21
    • 0037089084 scopus 로고    scopus 로고
    • Membrane topology and mitochondrial targeting of mitofusins, ubiquitous mammalian homologs of the transmembrane GTPase Fzo
    • Rojo M., Legros F., Chateau D., and Lombes A. Membrane topology and mitochondrial targeting of mitofusins, ubiquitous mammalian homologs of the transmembrane GTPase Fzo. J. Cell Sci. 115 (2002) 1663-1674
    • (2002) J. Cell Sci. , vol.115 , pp. 1663-1674
    • Rojo, M.1    Legros, F.2    Chateau, D.3    Lombes, A.4
  • 22
    • 0037434879 scopus 로고    scopus 로고
    • Fusion of mitochondria in mammalian cells is dependent on the mitochondrial inner membrane potential and independent of microtubules or actin
    • Mattenberger Y., James D.I., and Martinou J.C. Fusion of mitochondria in mammalian cells is dependent on the mitochondrial inner membrane potential and independent of microtubules or actin. FEBS Lett. 538 (2003) 53-59
    • (2003) FEBS Lett. , vol.538 , pp. 53-59
    • Mattenberger, Y.1    James, D.I.2    Martinou, J.C.3
  • 23
    • 0022492812 scopus 로고
    • Rhodamine 123 as a probe of transmembrane potential in isolated rat-liver mitochondria: spectral and metabolic properties
    • Emaus R.K., Grunwald R., and Lemasters J.J. Rhodamine 123 as a probe of transmembrane potential in isolated rat-liver mitochondria: spectral and metabolic properties. Biochim. Biophys. Acta 850 (1986) 436-448
    • (1986) Biochim. Biophys. Acta , vol.850 , pp. 436-448
    • Emaus, R.K.1    Grunwald, R.2    Lemasters, J.J.3
  • 24
    • 36549057064 scopus 로고
    • Age changes in size and number of the giant mitochondria in the flight muscle of the common housefly (Musca domestica L.)
    • Rockstein M., and Bhatnagar P.L. Age changes in size and number of the giant mitochondria in the flight muscle of the common housefly (Musca domestica L.). J. Insect Physiol. 11 (1965) 481-491
    • (1965) J. Insect Physiol. , vol.11 , pp. 481-491
    • Rockstein, M.1    Bhatnagar, P.L.2
  • 25
    • 0029311281 scopus 로고
    • Chimeric green fluorescent protein as a tool for visualizing subcellular organelles in living cells
    • Rizzuto R., Brini M., Pizzo P., Murgia M., and Pozzan T. Chimeric green fluorescent protein as a tool for visualizing subcellular organelles in living cells. Curr. Biol. 5 (1995) 635-642
    • (1995) Curr. Biol. , vol.5 , pp. 635-642
    • Rizzuto, R.1    Brini, M.2    Pizzo, P.3    Murgia, M.4    Pozzan, T.5
  • 26
    • 0031889998 scopus 로고    scopus 로고
    • Lipofuscin: mechanisms of formation and increase with age
    • Terman A., and Brunk U.T. Lipofuscin: mechanisms of formation and increase with age. APMIS 106 (1998) 265-276
    • (1998) APMIS , vol.106 , pp. 265-276
    • Terman, A.1    Brunk, U.T.2
  • 27
    • 27644526917 scopus 로고    scopus 로고
    • Testing the "garbage" accumulation theory of ageing: mitotic activity protects cells from death induced by inhibition of autophagy
    • Stroikin Y., Dalen H., Brunk U.T., and Terman A. Testing the "garbage" accumulation theory of ageing: mitotic activity protects cells from death induced by inhibition of autophagy. Biogerontology 6 (2005) 39-47
    • (2005) Biogerontology , vol.6 , pp. 39-47
    • Stroikin, Y.1    Dalen, H.2    Brunk, U.T.3    Terman, A.4
  • 28
    • 0042160077 scopus 로고    scopus 로고
    • Mitochondrial membrane fusion
    • Westermann B. Mitochondrial membrane fusion. Biochim. Biophys. Acta 1641 (2003) 195-202
    • (2003) Biochim. Biophys. Acta , vol.1641 , pp. 195-202
    • Westermann, B.1
  • 29
    • 0034938453 scopus 로고    scopus 로고
    • Human cells are protected from mitochondrial dysfunction by complementation of DNA products in fused mitochondria
    • Ono T., Isobe K., Nakada K., and Hayashi J.I. Human cells are protected from mitochondrial dysfunction by complementation of DNA products in fused mitochondria. Nat. Genet. 28 (2001) 272-275
    • (2001) Nat. Genet. , vol.28 , pp. 272-275
    • Ono, T.1    Isobe, K.2    Nakada, K.3    Hayashi, J.I.4
  • 30
    • 4544378532 scopus 로고    scopus 로고
    • Mitochondrial fusion intermediates revealed in vitro
    • Meeusen S., McCaffery J.M., and Nunnari J. Mitochondrial fusion intermediates revealed in vitro. Science 305 (2004) 1747-1752
    • (2004) Science , vol.305 , pp. 1747-1752
    • Meeusen, S.1    McCaffery, J.M.2    Nunnari, J.3
  • 31
    • 0345120940 scopus 로고    scopus 로고
    • Measurement of mitochondrial membrane potential using fluorescent rhodamine derivatives
    • Scaduto Jr. R.C., and Grotyohann L.W. Measurement of mitochondrial membrane potential using fluorescent rhodamine derivatives. Biophys. J. 76 (1999) 469-477
    • (1999) Biophys. J. , vol.76 , pp. 469-477
    • Scaduto Jr., R.C.1    Grotyohann, L.W.2
  • 32
    • 34250736372 scopus 로고    scopus 로고
    • Mitochondrial inner membrane electrophysiology assessed by rhodamine-123 transport and fluorescence
    • Huang M., Camara A.K., Stowe D.F., Qi F., and Beard D.A. Mitochondrial inner membrane electrophysiology assessed by rhodamine-123 transport and fluorescence. Ann. Biomed. Eng. 35 (2007) 1276-1285
    • (2007) Ann. Biomed. Eng. , vol.35 , pp. 1276-1285
    • Huang, M.1    Camara, A.K.2    Stowe, D.F.3    Qi, F.4    Beard, D.A.5
  • 33
    • 4644273585 scopus 로고    scopus 로고
    • Uth1p is involved in the autophagic degradation of mitochondria
    • Kissova I., Deffieu M., Manon S., and Camougrand N. Uth1p is involved in the autophagic degradation of mitochondria. J. Biol. Chem. 279 (2004) 39068-39074
    • (2004) J. Biol. Chem. , vol.279 , pp. 39068-39074
    • Kissova, I.1    Deffieu, M.2    Manon, S.3    Camougrand, N.4
  • 34
    • 27744491193 scopus 로고    scopus 로고
    • Emerging functions of mammalian mitochondrial fusion and fission
    • [Spec No. 2]
    • Chen H., and Chan D.C. Emerging functions of mammalian mitochondrial fusion and fission. Hum. Mol. Genet. 14 (2005) R283-R289 [Spec No. 2]
    • (2005) Hum. Mol. Genet. , vol.14
    • Chen, H.1    Chan, D.C.2
  • 35
    • 0024148694 scopus 로고
    • Mitochondrial membrane potential in living cells
    • Chen L.B. Mitochondrial membrane potential in living cells. Annu. Rev. Cell Biol. 4 (1988) 155-181
    • (1988) Annu. Rev. Cell Biol. , vol.4 , pp. 155-181
    • Chen, L.B.1
  • 36
    • 0018665167 scopus 로고
    • Membrane potential of mitochondria measured with an electrode sensitive to tetraphenyl phosphonium and relationship between proton electrochemical potential and phosphorylation potential in steady state
    • Kamo N., Muratsugu M., Hongoh R., and Kobatake Y. Membrane potential of mitochondria measured with an electrode sensitive to tetraphenyl phosphonium and relationship between proton electrochemical potential and phosphorylation potential in steady state. J. Membr. Biol. 49 (1979) 105-121
    • (1979) J. Membr. Biol. , vol.49 , pp. 105-121
    • Kamo, N.1    Muratsugu, M.2    Hongoh, R.3    Kobatake, Y.4


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