-
1
-
-
0025163524
-
Too many rodent carcinogens: Mitogenesis increases mutagenesis
-
Ames BN and Gold LS (1990) Too many rodent carcinogens: mitogenesis increases mutagenesis. Science 249: 970-971
-
(1990)
Science
, vol.249
, pp. 970-971
-
-
Ames, B.N.1
Gold, L.S.2
-
2
-
-
0031916984
-
The free radical theory of aging matures
-
Beckman KB and Ames BN (1998) The free radical theory of aging matures. Physiol Rev 78: 547-581
-
(1998)
Physiol Rev
, vol.78
, pp. 547-581
-
-
Beckman, K.B.1
Ames, B.N.2
-
3
-
-
0043204997
-
The anti-ageing effects of caloric restriction may involve stimulation of macroautophagy and lysosomal degradation, and can be intensified pharmacologically
-
Bergamini E, Cavallini G, Donati A and Gori Z (2003) The anti-ageing effects of caloric restriction may involve stimulation of macroautophagy and lysosomal degradation, and can be intensified pharmacologically. Biomed Pharmacother 57: 203-208
-
(2003)
Biomed Pharmacother
, vol.57
, pp. 203-208
-
-
Bergamini, E.1
Cavallini, G.2
Donati, A.3
Gori, Z.4
-
4
-
-
8044257699
-
The phosphatidylinositol 3-kinase inhibitors wortmannin and LY294002 inhibit autophagy in isolated rat hepatocytes
-
Blommaart EF, Krause U, Schellens JP, Vreeling-Sindelarova H and Meijer AJ (1997) The phosphatidylinositol 3-kinase inhibitors wortmannin and LY294002 inhibit autophagy in isolated rat hepatocytes. Eur J Biochem 243: 240-246
-
(1997)
Eur J Biochem
, vol.243
, pp. 240-246
-
-
Blommaart, E.F.1
Krause, U.2
Schellens, J.P.3
Vreeling-Sindelarova, H.4
Meijer, A.J.5
-
5
-
-
0036710928
-
Lipofuscin: Mechanisms of age-related accumulation and influence on cell functions
-
Brunk UT and Terman A (2002a) Lipofuscin: mechanisms of age-related accumulation and influence on cell functions. Free Radic Biol Med 33: 611-619
-
(2002)
Free Radic Biol Med
, vol.33
, pp. 611-619
-
-
Brunk, U.T.1
Terman, A.2
-
6
-
-
0036236006
-
The mitochondrial-lysosomal axis theory of aging: Accumulation of damaged mitochondria as a result of imperfect autophagocytosis
-
Brunk UT and Terman A (2002b) The mitochondrial-lysosomal axis theory of aging: accumulation of damaged mitochondria as a result of imperfect autophagocytosis. Eur J Biochem 269: 1996-2002
-
(2002)
Eur J Biochem
, vol.269
, pp. 1996-2002
-
-
Brunk, U.T.1
Terman, A.2
-
7
-
-
0015910768
-
A genetic interpretation of ageing
-
Burnet FM (1973) A genetic interpretation of ageing. Lancet 2: 480-483
-
(1973)
Lancet
, vol.2
, pp. 480-483
-
-
Burnet, F.M.1
-
8
-
-
0033796250
-
Mitochondrial free radical generation, oxidative stress, and aging
-
Cadenas E and Davies KJ (2000) Mitochondrial free radical generation, oxidative stress, and aging. Free Radic Biol Med 29: 222-230
-
(2000)
Free Radic Biol Med
, vol.29
, pp. 222-230
-
-
Cadenas, E.1
Davies, K.J.2
-
9
-
-
0030025660
-
Replicative senescence: An old lives' tale?
-
Campisi J (1996) Replicative senescence: an old lives' tale? Cell 84: 497-500
-
(1996)
Cell
, vol.84
, pp. 497-500
-
-
Campisi, J.1
-
10
-
-
0034069237
-
Cancer, aging and cellular senescence
-
Campisi J (2000) Cancer, aging and cellular senescence. In Vivo 14: 183-188
-
(2000)
In Vivo
, vol.14
, pp. 183-188
-
-
Campisi, J.1
-
11
-
-
0036843801
-
Bioremediation meets biomedicine: Therapeutic translation of microbial catabolism to the lysosome
-
de Grey AD (2002) Bioremediation meets biomedicine: therapeutic translation of microbial catabolism to the lysosome. Trends Biotechnol 20: 452-455
-
(2002)
Trends Biotechnol
, vol.20
, pp. 452-455
-
-
De Grey, A.D.1
-
12
-
-
0036815421
-
Mild stress-induced stimulation of heat-shock protein synthesis and improved functional ability of human fibroblasts undergoing aging in vitro
-
Fonager J, Beedholm R, Clark BF and Rattan SI (2002) Mild stress-induced stimulation of heat-shock protein synthesis and improved functional ability of human fibroblasts undergoing aging in vitro. Exp Gerontol 37: 1223-1228
-
(2002)
Exp Gerontol
, vol.37
, pp. 1223-1228
-
-
Fonager, J.1
Beedholm, R.2
Clark, B.F.3
Rattan, S.I.4
-
13
-
-
2342585484
-
Autolysosomes accumulate during in vitro CD8(+) T-lymphocyte aging and may participate in induced death sensitization of senescent cells
-
Gerland LM, Genestier L, Peyrol S, Michallet MC, Hayette S, Urbanowicz I, Ffrench P, Magaud JP and Ffrench M (2004) Autolysosomes accumulate during in vitro CD8(+) T-lymphocyte aging and may participate in induced death sensitization of senescent cells. Exp Gerontol 39: 789-800
-
(2004)
Exp Gerontol
, vol.39
, pp. 789-800
-
-
Gerland, L.M.1
Genestier, L.2
Peyrol, S.3
Michallet, M.C.4
Hayette, S.5
Urbanowicz, I.6
Ffrench, P.7
Magaud, J.P.8
Ffrench, M.9
-
14
-
-
0346727127
-
Protein degradation and protection against misfolded or damaged proteins
-
Goldberg AL (2003) Protein degradation and protection against misfolded or damaged proteins. Nature 426: 895-899
-
(2003)
Nature
, vol.426
, pp. 895-899
-
-
Goldberg, A.L.1
-
15
-
-
0038239701
-
Selective degradation of oxidatively modified protein substrates by the proteasome
-
Grune T, Merker K, Sandig G and Davies KJ (2003) Selective degradation of oxidatively modified protein substrates by the proteasome. Biochem Biophys Res Commun 305: 709-718
-
(2003)
Biochem Biophys Res Commun
, vol.305
, pp. 709-718
-
-
Grune, T.1
Merker, K.2
Sandig, G.3
Davies, K.J.4
-
16
-
-
77049308856
-
Aging: A theory based on free radical and radiation chemistry
-
Harman D (1956) Aging: a theory based on free radical and radiation chemistry. J Gerontol 211: 298-300
-
(1956)
J Gerontol
, vol.211
, pp. 298-300
-
-
Harman, D.1
-
17
-
-
0018149312
-
The waste-product theory of aging: Waste dilution by cell division
-
Hirsch HR (1978) The waste-product theory of aging: waste dilution by cell division. Mech Ageing Dev 8: 51-62
-
(1978)
Mech Ageing Dev
, vol.8
, pp. 51-62
-
-
Hirsch, H.R.1
-
18
-
-
0021675999
-
Inhibitors of lysosomal enzymes: Accumulation of lipofuscin-like dense bodies in the brain
-
Ivy GO, Schottler F, Wenzel J, Baudry M and Lynch G (1984) Inhibitors of lysosomal enzymes: accumulation of lipofuscin-like dense bodies in the brain. Science 226: 985-987
-
(1984)
Science
, vol.226
, pp. 985-987
-
-
Ivy, G.O.1
Schottler, F.2
Wenzel, J.3
Baudry, M.4
Lynch, G.5
-
19
-
-
0024546310
-
DNA, mutations and aging
-
Kirkwood TB (1989) DNA, mutations and aging. Mutat Res 219: 1-7
-
(1989)
Mutat Res
, vol.219
, pp. 1-7
-
-
Kirkwood, T.B.1
-
20
-
-
0035433420
-
Four deaths and a funeral: From caspases to alternative mechanisms
-
Leist M and Jaattela M (2001) Four deaths and a funeral: from caspases to alternative mechanisms. Nat Rev Mol Cell Biol 2: 589-598
-
(2001)
Nat Rev Mol Cell Biol
, vol.2
, pp. 589-598
-
-
Leist, M.1
Jaattela, M.2
-
21
-
-
2342560593
-
Caspase-independent cell death?
-
Lockshin RA and Zakeri Z (2004) Caspase-independent cell death? Oncogene 23: 2766-2773
-
(2004)
Oncogene
, vol.23
, pp. 2766-2773
-
-
Lockshin, R.A.1
Zakeri, Z.2
-
22
-
-
0344734108
-
Mortality patterns suggest lack of senescence in hydra
-
Martinez DE (1998) Mortality patterns suggest lack of senescence in hydra. Exp Gerontol 33: 217-225
-
(1998)
Exp Gerontol
, vol.33
, pp. 217-225
-
-
Martinez, D.E.1
-
23
-
-
0042691506
-
Autophagy genes are essential for dauer development and life-span extension in C. elegans
-
Melendez A, Talloczy Z, Seaman M, Eskelinen EL, Hall DH and Levine B (2003) Autophagy genes are essential for dauer development and life-span extension in C. elegans. Science 301: 1387-1391
-
(2003)
Science
, vol.301
, pp. 1387-1391
-
-
Melendez, A.1
Talloczy, Z.2
Seaman, M.3
Eskelinen, E.L.4
Hall, D.H.5
Levine, B.6
-
24
-
-
0015932795
-
Ageing of clones of mammalian cells
-
Orgel LE (1973) Ageing of clones of mammalian cells. Nature 243: 441-445
-
(1973)
Nature
, vol.243
, pp. 441-445
-
-
Orgel, L.E.1
-
25
-
-
0033978633
-
Distinct classes of phosphatidylinositol 3′-kinases are involved in signaling pathways that control macroautophagy in HT-29 cells
-
Petiot A, Ogier-Denis E, Blommaart EF, Meijer AJ and Codogno P (2000) Distinct classes of phosphatidylinositol 3′-kinases are involved in signaling pathways that control macroautophagy in HT-29 cells. J Biol Chem 275: 992-998
-
(2000)
J Biol Chem
, vol.275
, pp. 992-998
-
-
Petiot, A.1
Ogier-Denis, E.2
Blommaart, E.F.3
Meijer, A.J.4
Codogno, P.5
-
26
-
-
0016322191
-
The ageing, growth and death of cells
-
Sheldrake AR (1974) The ageing, growth and death of cells. Nature 250: 381-385
-
(1974)
Nature
, vol.250
, pp. 381-385
-
-
Sheldrake, A.R.1
-
27
-
-
0026023219
-
Hydrogen peroxide release by mitochondria increases during aging
-
Sohal RS and Sohal BH (1991) Hydrogen peroxide release by mitochondria increases during aging. Mech Ageing Dev 57: 187-202
-
(1991)
Mech Ageing Dev
, vol.57
, pp. 187-202
-
-
Sohal, R.S.1
Sohal, B.H.2
-
28
-
-
0035063178
-
Garbage catastrophe theory of aging: Imperfect removal of oxidative damage?
-
Terman A (2001) Garbage catastrophe theory of aging: imperfect removal of oxidative damage? Redox Rep 6: 15-26
-
(2001)
Redox Rep
, vol.6
, pp. 15-26
-
-
Terman, A.1
-
29
-
-
0032821609
-
Ceroid/lipofuscin-Loaded human fibroblasts show increased susceptibility to oxidative stress
-
Terman A, Abrahamsson N and Brunk UT (1999a) Ceroid/lipofuscin-loaded human fibroblasts show increased susceptibility to oxidative stress. Exp Gerontol 34: 755-770
-
(1999)
Exp Gerontol
, vol.34
, pp. 755-770
-
-
Terman, A.1
Abrahamsson, N.2
Brunk, U.T.3
-
30
-
-
0032169551
-
Ceroid/lipofuscin formation in cultured human fibroblasts: The role of oxidative stress and lysosomal proteolysis
-
Terman A and Brunk UT (1998) Ceroid/lipofuscin formation in cultured human fibroblasts: the role of oxidative stress and lysosomal proteolysis. Mech Ageing Dev 104: 277-291
-
(1998)
Mech Ageing Dev
, vol.104
, pp. 277-291
-
-
Terman, A.1
Brunk, U.T.2
-
32
-
-
0032730787
-
Ceroid/lipofuscin-loaded human fibroblasts show decreased survival time and diminished autophagocytosis during amino acid starvation
-
Terman A, Dalen H and Brunk UT (1999b) Ceroid/lipofuscin-loaded human fibroblasts show decreased survival time and diminished autophagocytosis during amino acid starvation. Exp Gerontol 34: 943-957
-
(1999)
Exp Gerontol
, vol.34
, pp. 943-957
-
-
Terman, A.1
Dalen, H.2
Brunk, U.T.3
-
33
-
-
0042707790
-
Mitochondrial recycling and aging of cardiac myocytes: The role of autophagocytosis
-
Terman A, Dalen H, Eaton JW, Neuzil J and Brunk UT (2003) Mitochondrial recycling and aging of cardiac myocytes: the role of autophagocytosis. Exp Gerontol 38: 863-876
-
(2003)
Exp Gerontol
, vol.38
, pp. 863-876
-
-
Terman, A.1
Dalen, H.2
Eaton, J.W.3
Neuzil, J.4
Brunk, U.T.5
-
35
-
-
0031040134
-
Measurement of apoptosis in heterogenous cell populations
-
Weber GF, Daley J, Kraeft SK, Chen LB and Cantor H (1997) Measurement of apoptosis in heterogenous cell populations. Cytometry 27: 136-144
-
(1997)
Cytometry
, vol.27
, pp. 136-144
-
-
Weber, G.F.1
Daley, J.2
Kraeft, S.K.3
Chen, L.B.4
Cantor, H.5
|