Predicting the Effect of a Point Mutation on a Protein Fold: The Villin and Advillin Headpieces and Their Pro62Ala Mutants

Journal of Molecular Biology

Volumn 375, Issue 2, 2008, Pages 460-470

  Piana, Stefano ^a   Laio, Alessandro ^b   Marinelli, Fabrizio ^b   Van Troys, Marleen ^c   Bourry, David ^c,d   Ampe, Christophe ^c   Martins, José C ^d  

^a CURTIN UNIVERSITY   (Australia)

^b SISSA   (Italy)

^c GHENT UNIVERSITY   (Belgium)

^d NMR   (Belgium)

Author keywords

advillin headpiece; metadynamics; molecular dynamics simulation; protein folding; villin headpiece

Indexed keywords

ADVILLIN; ALANINE; BINDING PROTEIN; MUTANT PROTEIN; PROLINE; UNCLASSIFIED DRUG; VILLIN;

AMINO ACID SEQUENCE; ARTICLE; POINT MUTATION; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN FOLDING; PROTEIN STRUCTURE; PROTEOMICS; SEQUENCE HOMOLOGY; SIMULATION; STRUCTURE ANALYSIS;

EID: 36548999391     PISSN: 00222836     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jmb.2007.10.020     Document Type: Article

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