-
1
-
-
0030834058
-
Human cytochrome P450 enzymes: A status report summarizing their reactions, substrates, inducers, and inhibitors
-
Rendic S, Di Carlo FJ: Human cytochrome P450 enzymes: a status report summarizing their reactions, substrates, inducers, and inhibitors. Drug Metab. Rev. 29, 413-580 (1997).
-
(1997)
Drug Metab. Rev
, vol.29
, pp. 413-580
-
-
Rendic, S.1
Di Carlo, F.J.2
-
2
-
-
0033588022
-
Lipoxygenases: Occurrence, functions, catalysis, and acquisition of substrate
-
Brash AR: Lipoxygenases: occurrence, functions, catalysis, and acquisition of substrate. J. Biol. Chem. 274, 23679-23682 (1999)
-
(1999)
J. Biol. Chem
, vol.274
, pp. 23679-23682
-
-
Brash, A.R.1
-
3
-
-
0019195393
-
Prostaglandins, arachidonic acid, and inflammation
-
Kuehl FA Jr, Egan RW: Prostaglandins, arachidonic acid, and inflammation. Science 210, 978-984 (1980).
-
(1980)
Science
, vol.210
, pp. 978-984
-
-
Kuehl Jr, F.A.1
Egan, R.W.2
-
4
-
-
0030479496
-
Prostaglandin endoperoxide H synthases (cyclooxygenases) -1 and -2
-
Smith WL, Garavito RM, DeWitt DL: Prostaglandin endoperoxide H synthases (cyclooxygenases) -1 and -2. J. Biol. Chem. 271, 33157-33160 (1996).
-
(1996)
J. Biol. Chem
, vol.271
, pp. 33157-33160
-
-
Smith, W.L.1
Garavito, R.M.2
DeWitt, D.L.3
-
5
-
-
0036080081
-
P-450 metabolites of arachidonic acid in the control of cardiovascular function
-
Roman RJ: P-450 metabolites of arachidonic acid in the control of cardiovascular function. Physiol. Rev. 82, 131-195 (2002).
-
(2002)
Physiol. Rev
, vol.82
, pp. 131-195
-
-
Roman, R.J.1
-
6
-
-
0035965327
-
Epoxygenase pathways of arachidonic acid metabolism
-
Zeldin DC: Epoxygenase pathways of arachidonic acid metabolism. J. Biol. Chem. 276, 36059-36062 (2001).
-
(2001)
J. Biol. Chem
, vol.276
, pp. 36059-36062
-
-
Zeldin, D.C.1
-
7
-
-
1842430562
-
Distribution of soluble epoxide hydrolase and of cytochrome P450 2C8. 2C9, and 2J2 in human tissues
-
Enayetallah AE, French RA, Thibodeau MS, Grant DF: Distribution of soluble epoxide hydrolase and of cytochrome P450 2C8. 2C9, and 2J2 in human tissues. J. Histochem. Cytochem. 52, 447-454 (2004).
-
(2004)
J. Histochem. Cytochem
, vol.52
, pp. 447-454
-
-
Enayetallah, A.E.1
French, R.A.2
Thibodeau, M.S.3
Grant, D.F.4
-
8
-
-
0033588034
-
Anti-inflammatory properties of cytochrome P450 epoxygenase-derived eicosanoids
-
Node K, Huo Y, Ruan X et al.: Anti-inflammatory properties of cytochrome P450 epoxygenase-derived eicosanoids. Science 285, 1276-1279 (1999).
-
(1999)
Science
, vol.285
, pp. 1276-1279
-
-
Node, K.1
Huo, Y.2
Ruan, X.3
-
9
-
-
33644849675
-
Epoxyeicosatrienoic and dihydroxyeicosatrienoic acids dilate human coronary arterioles via BK(Ca) channels: Implications for soluble epoxide hydrolase inhibition
-
Larsen BT, Miura H, Hatoum OA et al.: Epoxyeicosatrienoic and dihydroxyeicosatrienoic acids dilate human coronary arterioles via BK(Ca) channels: implications for soluble epoxide hydrolase inhibition. Am. J. Physiol. Heart Circ. Physiol. 290, H491-499 (2006).
-
(2006)
Am. J. Physiol. Heart Circ. Physiol
, vol.290
-
-
Larsen, B.T.1
Miura, H.2
Hatoum, O.A.3
-
10
-
-
0030051805
-
Identification of epoxyeicosatrienoic acids as endothelium-derived hyperpolarizing factors
-
Campbell WB, Gebremedhin D, Pratt PF, Harder DR: Identification of epoxyeicosatrienoic acids as endothelium-derived hyperpolarizing factors. Circ. Res. 78, 415-423 (1996).
-
(1996)
Circ. Res
, vol.78
, pp. 415-423
-
-
Campbell, W.B.1
Gebremedhin, D.2
Pratt, P.F.3
Harder, D.R.4
-
11
-
-
0033619262
-
Cytochrome P450 2C is an EDHF synthase in coronary arteries
-
Fisslthaler B, Popp R, Kiss L et al.: Cytochrome P450 2C is an EDHF synthase in coronary arteries. Nature 401, 493-497 (1999).
-
(1999)
Nature
, vol.401
, pp. 493-497
-
-
Fisslthaler, B.1
Popp, R.2
Kiss, L.3
-
12
-
-
28044434102
-
The antiinflammatory effect of laminar flow: The role of PPARgamma, epoxyeicosatrienoic acids. and soluble epoxide hydrolase
-
Liu Y, Zhang Y, Schmelzer K et al.: The antiinflammatory effect of laminar flow: the role of PPARgamma, epoxyeicosatrienoic acids. and soluble epoxide hydrolase. Proc. Natl Acad. Sci. USA 102, 16747-16752 (2005).
-
(2005)
Proc. Natl Acad. Sci. USA
, vol.102
, pp. 16747-16752
-
-
Liu, Y.1
Zhang, Y.2
Schmelzer, K.3
-
13
-
-
22244443733
-
Soluble epoxide hydrolase is a therapeutic target for acute inflammation
-
Schmeizer KR, Kubala L. Newman JW, Kim IH, Eiserich JP, Hammock BD: Soluble epoxide hydrolase is a therapeutic target for acute inflammation. Proc. Natl Acad. Sci. USA 102, 9772-9777 (2005).
-
(2005)
Proc. Natl Acad. Sci. USA
, vol.102
, pp. 9772-9777
-
-
Schmeizer, K.R.1
Kubala, L.2
Newman, J.W.3
Kim, I.H.4
Eiserich, J.P.5
Hammock, B.D.6
-
14
-
-
4444236138
-
Enhanced postischemic functional recovery in CYP2J2 transgenic hearts involves mitochondrial ATP-sensitive K+ channels and p42/p44 MAPK pathway
-
Seubert J. Yang B, Bradbury JA et al.: Enhanced postischemic functional recovery in CYP2J2 transgenic hearts involves mitochondrial ATP-sensitive K+ channels and p42/p44 MAPK pathway. Circ. Res. 95, 506-514 (2004).
-
(2004)
Circ. Res
, vol.95
, pp. 506-514
-
-
Seubert, J.1
Yang, B.2
Bradbury, J.A.3
-
15
-
-
33747422507
-
Role of soluble epoxide hydrolase in postischemic recovery of heart contractile function
-
Seubert JM, Sinal CJ, Graves J et al.: Role of soluble epoxide hydrolase in postischemic recovery of heart contractile function. Circ. Res. 99, 442-450 (2006).
-
(2006)
Circ. Res
, vol.99
, pp. 442-450
-
-
Seubert, J.M.1
Sinal, C.J.2
Graves, J.3
-
16
-
-
33644697099
-
An epoxide hydrolase inhibitor, 12-(3-adamantan- 1 -y1-ureido)dodecanoic acid (AUDA), reduces ischemic cerebral infarct size in stroke-prone spontaneously hypertensive rats
-
Dorrance AM, Rupp N, Pollock DM, Newman JW, Hammock BD, Imig JD: An epoxide hydrolase inhibitor, 12-(3-adamantan- 1 -y1-ureido)dodecanoic acid (AUDA), reduces ischemic cerebral infarct size in stroke-prone spontaneously hypertensive rats. J. Cardiovasc. Pharmacol. 46, 842-848 (2005).
-
(2005)
J. Cardiovasc. Pharmacol
, vol.46
, pp. 842-848
-
-
Dorrance, A.M.1
Rupp, N.2
Pollock, D.M.3
Newman, J.W.4
Hammock, B.D.5
Imig, J.D.6
-
17
-
-
34247525219
-
Polymorphisms in the human soluble epoxide hydrolase gene EPHX2 linked to neuronal survival after ischemic injury
-
Koerner IP, Jacks R, DeBarber AE et al.. Polymorphisms in the human soluble epoxide hydrolase gene EPHX2 linked to neuronal survival after ischemic injury. J. Neurosci. 27, 4642-4649 (2007).
-
(2007)
J. Neurosci
, vol.27
, pp. 4642-4649
-
-
Koerner, I.P.1
Jacks, R.2
DeBarber, A.E.3
-
18
-
-
0035844126
-
Activation of G alphas mediates induction of tissue-type plasminogen activator gene transcription by epoxyeicosatrienoic acids
-
Node K, Ruan XL, Dai J et al.: Activation of G alphas mediates induction of tissue-type plasminogen activator gene transcription by epoxyeicosatrienoic acids. J. Biol. Chem. 276, 15983-15989(2001).
-
(2001)
J. Biol. Chem
, vol.276
, pp. 15983-15989
-
-
Node, K.1
Ruan, X.L.2
Dai, J.3
-
19
-
-
0034109792
-
Cerebral microvascular endothelial cell tube formation: Role of astrocytic epoxyeicosatrienoic acid release
-
Munzenmaier DH, Harder DR: Cerebral microvascular endothelial cell tube formation: role of astrocytic epoxyeicosatrienoic acid release. Am. J. Physiol. Heart Circ. Physiol. 278, H1163-1167 (2000).
-
(2000)
Am. J. Physiol. Heart Circ. Physiol
, vol.278
-
-
Munzenmaier, D.H.1
Harder, D.R.2
-
20
-
-
0037123925
-
Inhibition of vascular smooth muscle cell migration by cytochrome p450 epoxygenase-derived eicosanoids
-
Sun J. Sui X, Bradbury JA, Zeldin DC, Conte MS, Liao JK: Inhibition of vascular smooth muscle cell migration by cytochrome p450 epoxygenase-derived eicosanoids. Circ. Res. 90, 1020-1027 (2002).
-
(2002)
Circ. Res
, vol.90
, pp. 1020-1027
-
-
Sun, J.1
Sui, X.2
Bradbury, J.A.3
Zeldin, D.C.4
Conte, M.S.5
Liao, J.K.6
-
21
-
-
0034704156
-
Targeted disruption of soluble epoxide hydrolase reveals a role in blood pressure regulation
-
Sinal CJ, Miyata M, Tohkin M, Nagata K, Bend JR, Gonzalez FJ: Targeted disruption of soluble epoxide hydrolase reveals a role in blood pressure regulation. J. Biol. Chem. 275, 40504-40510, (2000).
-
(2000)
J. Biol. Chem
, vol.275
, pp. 40504-40510
-
-
Sinal, C.J.1
Miyata, M.2
Tohkin, M.3
Nagata, K.4
Bend, J.R.5
Gonzalez, F.J.6
-
22
-
-
36448975919
-
-
Imig JD, Zhao X, Capdevila JH, Morisseau C, Hammock BD: Soluble epoxide hydrolase inhibition lowers arterial blood pressure in angiotensin II hypertension
-
Imig JD, Zhao X, Capdevila JH, Morisseau C, Hammock BD: Soluble epoxide hydrolase inhibition lowers arterial blood pressure in angiotensin II hypertension.
-
-
-
-
23
-
-
33644654633
-
An orally active epoxide hydrolase inhibitor lowers blood pressure and provides renal protection in salt-sensitive hypertension
-
Imig JD, Zhao X, Zaharis CZ et al.: An orally active epoxide hydrolase inhibitor lowers blood pressure and provides renal protection in salt-sensitive hypertension. Hypertension 46, 975-981 (2005).
-
(2005)
Hypertension
, vol.46
, pp. 975-981
-
-
Imig, J.D.1
Zhao, X.2
Zaharis, C.Z.3
-
24
-
-
18244406298
-
Nuclear factor κB signaling in atherogenesis
-
de Winther MP, Kanters E, Kraal G, Hofker MH: Nuclear factor κB signaling in atherogenesis. Arterioscler. Thromb. Vasc. Biol. 25, 904-914 (2005).
-
(2005)
Arterioscler. Thromb. Vasc. Biol
, vol.25
, pp. 904-914
-
-
de Winther, M.P.1
Kanters, E.2
Kraal, G.3
Hofker, M.H.4
-
25
-
-
0037144475
-
The CYP4A isoforms hydroxylate epoxyeicosatrienoic acids to form high affinity peroxisome proliferator-activated receptor ligands
-
Cowart LA, Wei S, Hsu MH et al.: The CYP4A isoforms hydroxylate epoxyeicosatrienoic acids to form high affinity peroxisome proliferator-activated receptor ligands. J. Biol. Chem. 277, 35105-35112 (2002).
-
(2002)
J. Biol. Chem
, vol.277
, pp. 35105-35112
-
-
Cowart, L.A.1
Wei, S.2
Hsu, M.H.3
-
26
-
-
0030063499
-
Molecular cloning and expression of CYP2J2, a human cytochrome P450 arachidonic acid epoxygenase highly expressed in heart
-
Wu S, Moomaw CR, Tomer KB, Falck JR, Zeldin DC: Molecular cloning and expression of CYP2J2, a human cytochrome P450 arachidonic acid epoxygenase highly expressed in heart. J. Biol. Chem. 271. 3460-3468 (1996).
-
(1996)
J. Biol. Chem
, vol.271
, pp. 3460-3468
-
-
Wu, S.1
Moomaw, C.R.2
Tomer, K.B.3
Falck, J.R.4
Zeldin, D.C.5
-
27
-
-
33751191888
-
Variability of CYP2J2 expression in human fetal tissues
-
Gaedigk A, Baker DW, Totah RA et al.: Variability of CYP2J2 expression in human fetal tissues. J. Pharmacol. Exp. Ther. 319, 523-532 (2006).
-
(2006)
J. Pharmacol. Exp. Ther
, vol.319
, pp. 523-532
-
-
Gaedigk, A.1
Baker, D.W.2
Totah, R.A.3
-
28
-
-
18344377326
-
Cloning of CYP2J2 gene and identification of functional polymorphisms
-
King LM, Ma J, Srettabunjong S et al.: Cloning of CYP2J2 gene and identification of functional polymorphisms. Mol. Pharmacol. 61, 840-852 (2002).
-
(2002)
Mol. Pharmacol
, vol.61
, pp. 840-852
-
-
King, L.M.1
Ma, J.2
Srettabunjong, S.3
-
29
-
-
17644385223
-
Identification and functional characterization of novel CYP2J2 variants: G312R variant causes loss of enzyme catalytic activity
-
Lee SS, Jeong HE, Liu KH et al.: Identification and functional characterization of novel CYP2J2 variants: G312R variant causes loss of enzyme catalytic activity. Pharmacogenet. Genomics 15, 105-113 (2005).
-
(2005)
Pharmacogenet. Genomics
, vol.15
, pp. 105-113
-
-
Lee, S.S.1
Jeong, H.E.2
Liu, K.H.3
-
30
-
-
33845712373
-
Inter-individual variation of cytochrome P4502J2 expression and catalytic activities in liver microsomes from Japanese and Caucasian populations
-
Yamazaki H, Okayama A, Imai N, Guengerich FP, Shimizu M: Inter-individual variation of cytochrome P4502J2 expression and catalytic activities in liver microsomes from Japanese and Caucasian populations. Xenobiotica 36, 1201-1209 (2006).
-
(2006)
Xenobiotica
, vol.36
, pp. 1201-1209
-
-
Yamazaki, H.1
Okayama, A.2
Imai, N.3
Guengerich, F.P.4
Shimizu, M.5
-
31
-
-
20844452556
-
Risk of coronary artery disease associated with polymorphism of the cytochrome P450 epoxygenase CYP2J2
-
Spiecker M, Darius H, Hankein T et al.: Risk of coronary artery disease associated with polymorphism of the cytochrome P450 epoxygenase CYP2J2. Circulation 110, 2132-2136 (2004).
-
(2004)
Circulation
, vol.110
, pp. 2132-2136
-
-
Spiecker, M.1
Darius, H.2
Hankein, T.3
-
32
-
-
36448966070
-
Synergistic effect of cytochrome P450 epoxygenase CYP2J2*7 polymorphism with smoking on the onset of premature myocardial infarction
-
Epub ahead of print
-
Liu PY, Li YH, Chao TH et al.: Synergistic effect of cytochrome P450 epoxygenase CYP2J2*7 polymorphism with smoking on the onset of premature myocardial infarction. Atherosclerosis (2006) (Epub ahead of print).
-
(2006)
Atherosclerosis
-
-
Liu, P.Y.1
Li, Y.H.2
Chao, T.H.3
-
33
-
-
36448954380
-
-
Spiecker M, Zeldin DC, Mugge A, Tenderich G, Liao JK, Milting H: Reduced human myocardial mRNA expression of CYP2J2 in individuals with the G-50T promoter polymorphism. American Heart Association Scientific Sessions. Chicago, USA, Circulation 691, II-117 (2006).
-
Spiecker M, Zeldin DC, Mugge A, Tenderich G, Liao JK, Milting H: Reduced human myocardial mRNA expression of CYP2J2 in individuals with the G-50T promoter polymorphism. American Heart Association Scientific Sessions. Chicago, USA, Circulation 691, II-117 (2006).
-
-
-
-
34
-
-
33947419679
-
The -50G>T polymorphism in the promoter of the CYP2J2 gene in coronary heart disease: The Ludwigshafen Risk and Cardiovascular Health study
-
Hoffmann MM, Bogert P, Seelhorst U et al.: The -50G>T polymorphism in the promoter of the CYP2J2 gene in coronary heart disease: the Ludwigshafen Risk and Cardiovascular Health study. Clin. Chem. 53, 539-540 (2007).
-
(2007)
Clin. Chem
, vol.53
, pp. 539-540
-
-
Hoffmann, M.M.1
Bogert, P.2
Seelhorst, U.3
-
35
-
-
34247182994
-
CYP2J2 and CYP2C8 polymorphisms and coronary heart disease risk: The Atherosclerosis Risk in Communities (ARIC) study
-
Lee CR, North KE, Bray MS, Couper DJ, Heiss G, Zeldin DC: CYP2J2 and CYP2C8 polymorphisms and coronary heart disease risk: the Atherosclerosis Risk in Communities (ARIC) study. Pharmacogenet. Genomics 17, 349-358 (2007).
-
(2007)
Pharmacogenet. Genomics
, vol.17
, pp. 349-358
-
-
Lee, C.R.1
North, K.E.2
Bray, M.S.3
Couper, D.J.4
Heiss, G.5
Zeldin, D.C.6
-
36
-
-
85047278388
-
Single nucleotide polymorphisms in the CYP2J2 and CYP2C8 genes and the risk of hypertension
-
King LM, Gainer JV, David GL et al.: Single nucleotide polymorphisms in the CYP2J2 and CYP2C8 genes and the risk of hypertension. Pharmacogenet. Genomics 15, 7-13 (2005).
-
(2005)
Pharmacogenet. Genomics
, vol.15
, pp. 7-13
-
-
King, L.M.1
Gainer, J.V.2
David, G.L.3
-
37
-
-
34249869860
-
Evidence for association of polymorphisms in CYP2J2 and susceptibility to essential hypertension
-
Wu SN, Zhang Y, Gardner CO et al.: Evidence for association of polymorphisms in CYP2J2 and susceptibility to essential hypertension. Ann. Hum. Genet. 71, 519-525 (2007).
-
(2007)
Ann. Hum. Genet
, vol.71
, pp. 519-525
-
-
Wu, S.N.1
Zhang, Y.2
Gardner, C.O.3
-
38
-
-
25844438367
-
The Prevalence of CYP2C8, 2C9, 2J2, and soluble epoxide hydrolase polymorphisms in African Americans with hypertension
-
Dreisbach AW, Japa S, Sigel A et al.: The Prevalence of CYP2C8, 2C9, 2J2, and soluble epoxide hydrolase polymorphisms in African Americans with hypertension. Am. J. Hypertens. 18, 1276-1281 (2005).
-
(2005)
Am. J. Hypertens
, vol.18
, pp. 1276-1281
-
-
Dreisbach, A.W.1
Japa, S.2
Sigel, A.3
-
39
-
-
0242428240
-
Cytochrome P450 2J2 polymorphism in healthy Caucasians and those with diabetes mellitus
-
Pucci L, Lucchesi D, Chiruili V et al.: Cytochrome P450 2J2 polymorphism in healthy Caucasians and those with diabetes mellitus. Am. J. Pharmacogenomics. 3, 355-358 (2003).
-
(2003)
Am. J. Pharmacogenomics
, vol.3
, pp. 355-358
-
-
Pucci, L.1
Lucchesi, D.2
Chiruili, V.3
-
40
-
-
0028590127
-
Biochemistry and molecular biology of the human CYP2C subfamily
-
Goldstein JA, de Morais SM: Biochemistry and molecular biology of the human CYP2C subfamily. Pharmacogenetics 4, 285-299 (1994).
-
(1994)
Pharmacogenetics
, vol.4
, pp. 285-299
-
-
Goldstein, J.A.1
de Morais, S.M.2
-
41
-
-
0032604625
-
Gene structure of CYP2C8 and extrahepatic distribution of the human CYP2Cs
-
Klose TS, Blaisdell JA, Goldstein JA: Gene structure of CYP2C8 and extrahepatic distribution of the human CYP2Cs. J. Biochem. Mol. Toxicol. 13, 289-295 (1999).
-
(1999)
J. Biochem. Mol. Toxicol
, vol.13
, pp. 289-295
-
-
Klose, T.S.1
Blaisdell, J.A.2
Goldstein, J.A.3
-
43
-
-
19144368324
-
Cytochrome P450 2C8: Substrates, inhibitors, pharmacogenetics, and clinical relevance
-
Totah RA, Rettie AE: Cytochrome P450 2C8: substrates, inhibitors, pharmacogenetics, and clinical relevance. Clin. Pharmacol. Ther. 77, 341-352 (2005).
-
(2005)
Clin. Pharmacol. Ther
, vol.77
, pp. 341-352
-
-
Totah, R.A.1
Rettie, A.E.2
-
44
-
-
0036263813
-
Cytochrome P450 2C9 polymorphisms: A comprehensive review of the in vitro and human data
-
Lee CR, Goldstein JA, Pieper JA: Cytochrome P450 2C9 polymorphisms: a comprehensive review of the in vitro and human data. Pharmacogenetics 12, 251-263 (2002).
-
(2002)
Pharmacogenetics
, vol.12
, pp. 251-263
-
-
Lee, C.R.1
Goldstein, J.A.2
Pieper, J.A.3
-
45
-
-
0036889666
-
CYP2C8 polymorphisms in Caucasians and their relationship with paclitaxel 6α-hydroxylase activity in human liver microsomes
-
Bahadur N, Leathart JB, Mutch E et al.: CYP2C8 polymorphisms in Caucasians and their relationship with paclitaxel 6α-hydroxylase activity in human liver microsomes. Biochem. Pharmacol. 64, 1579-1589 (2002).
-
(2002)
Biochem. Pharmacol
, vol.64
, pp. 1579-1589
-
-
Bahadur, N.1
Leathart, J.B.2
Mutch, E.3
-
46
-
-
0034791777
-
Polymorphisms in human CYP2C8 decrease metabolism of the anticancer drug paclitaxel and arachidonic acid
-
Dai D, Zeldin DC, Blaisdell JA et al.: Polymorphisms in human CYP2C8 decrease metabolism of the anticancer drug paclitaxel and arachidonic acid. Pharmacogenetics 11, 597-607 (2001).
-
(2001)
Pharmacogenetics
, vol.11
, pp. 597-607
-
-
Dai, D.1
Zeldin, D.C.2
Blaisdell, J.A.3
-
47
-
-
0035214173
-
Non-synonymous single nucleotide alterations found in the CYP2C8 gene result in reduced in vitro paclitaxel metabolism
-
Soyama A, Saito Y, Hanioka N et al.: Non-synonymous single nucleotide alterations found in the CYP2C8 gene result in reduced in vitro paclitaxel metabolism. Biol. Pharm. Bull. 24, 1427-1430 (2001).
-
(2001)
Biol. Pharm. Bull
, vol.24
, pp. 1427-1430
-
-
Soyama, A.1
Saito, Y.2
Hanioka, N.3
-
48
-
-
12344278995
-
Biosynthesis of epoxyeicosatrienoic acids varies between polymorphic CYP2C enzymes
-
Lundblad MS, Stark K, Eliasson E, Oliw E, Rane A: Biosynthesis of epoxyeicosatrienoic acids varies between polymorphic CYP2C enzymes. Biochem. Biophys. Res. Commun. 327, 1052-1057 (2005).
-
(2005)
Biochem. Biophys. Res. Commun
, vol.327
, pp. 1052-1057
-
-
Lundblad, M.S.1
Stark, K.2
Eliasson, E.3
Oliw, E.4
Rane, A.5
-
49
-
-
0028210729
-
Impaired S-warfarin metabolism catalysed by the R144C allelic variant of CYP2C9
-
Rettie AE, Wienkers LC, Gonzalez FJ, Trager WF, Korzekwa KR: Impaired S-warfarin metabolism catalysed by the R144C allelic variant of CYP2C9. Pharmacogenetics 4, 39-42 (1994).
-
(1994)
Pharmacogenetics
, vol.4
, pp. 39-42
-
-
Rettie, A.E.1
Wienkers, L.C.2
Gonzalez, F.J.3
Trager, W.F.4
Korzekwa, K.R.5
-
50
-
-
0029658591
-
The role of the CYP2C9-Leu359 allelic variant in the tolbutamide polymorphism
-
Sullivan-Klose TH, Ghanavem BI, Bell DA et al.: The role of the CYP2C9-Leu359 allelic variant in the tolbutamide polymorphism. Pharmacogenetics 6, 341-349 (1996).
-
(1996)
Pharmacogenetics
, vol.6
, pp. 341-349
-
-
Sullivan-Klose, T.H.1
Ghanavem, B.I.2
Bell, D.A.3
-
51
-
-
1842558550
-
Allelic variants of cytochromes P450 2C modify the risk for acute myocardial infarction
-
Yasar U, Bennet AM, Eliasson E et al.: Allelic variants of cytochromes P450 2C modify the risk for acute myocardial infarction. Pharmacogenetics 13, 715-720 (2003).
-
(2003)
Pharmacogenetics
, vol.13
, pp. 715-720
-
-
Yasar, U.1
Bennet, A.M.2
Eliasson, E.3
-
52
-
-
34250222451
-
The risk of myocardial infarction in patients with reduced activity of cytochrome P450 2C9
-
Visser LE, van Schalk RH, Jan Danser AH et al.: The risk of myocardial infarction in patients with reduced activity of cytochrome P450 2C9. Pharmacogenet. Genomics 17, 473-479 (2007).
-
(2007)
Pharmacogenet. Genomics
, vol.17
, pp. 473-479
-
-
Visser, L.E.1
van Schalk, R.H.2
Jan Danser, A.H.3
-
53
-
-
0037452577
-
The soluble epoxide hydrolase encoded by EPXH2 is a bifunctional enzyme with novel lipid phosphate phosphatase activity
-
Newman JW, Morisseau C, Harris TR, Hammock BD: The soluble epoxide hydrolase encoded by EPXH2 is a bifunctional enzyme with novel lipid phosphate phosphatase activity. Proc. Natl Acad. Sci. USA 100, 1558-1563 (2003).
-
(2003)
Proc. Natl Acad. Sci. USA
, vol.100
, pp. 1558-1563
-
-
Newman, J.W.1
Morisseau, C.2
Harris, T.R.3
Hammock, B.D.4
-
54
-
-
0029984341
-
Structural characterization of the human soluble epoxide hydrolase gene (EPHX2)
-
Sandberg M, Meijer J: Structural characterization of the human soluble epoxide hydrolase gene (EPHX2). Biochem. Biophys. Res. Commun. 221, 333-339 (1996).
-
(1996)
Biochem. Biophys. Res. Commun
, vol.221
, pp. 333-339
-
-
Sandberg, M.1
Meijer, J.2
-
55
-
-
2942579253
-
Polymorphisms in human soluble epoxide hydrolase: Effects on enzyme activity, enzyme stability, and quaternary structure
-
Srivastava PK, Sharma VK, Kalonia DS, Grant DF: Polymorphisms in human soluble epoxide hydrolase: effects on enzyme activity, enzyme stability, and quaternary structure. Arch. Biochem. Biophys. 427, 164-169 (2004).
-
(2004)
Arch. Biochem. Biophys
, vol.427
, pp. 164-169
-
-
Srivastava, P.K.1
Sharma, V.K.2
Kalonia, D.S.3
Grant, D.F.4
-
57
-
-
0034666150
-
Identification and functional characterization of human soluble epoxide hydrolase genetic polymorphisms
-
Sandberg M, Hassett C, Adman ET, Meijer J, Omieciriski CJ: Identification and functional characterization of human soluble epoxide hydrolase genetic polymorphisms. J. Biol. Chem. 275, 28873-28881 (2000).
-
(2000)
J. Biol. Chem
, vol.275
, pp. 28873-28881
-
-
Sandberg, M.1
Hassett, C.2
Adman, E.T.3
Meijer, J.4
Omieciriski, C.J.5
-
58
-
-
33745222033
-
Genetic variation in soluble epoxide hydrolase (EPHX2) and risk of coronary heart disease: The Atherosclerosis Risk in Communities (ARIC) study
-
Lee CR, North KE, Bray MS et al.: Genetic variation in soluble epoxide hydrolase (EPHX2) and risk of coronary heart disease: The Atherosclerosis Risk in Communities (ARIC) study. Hum. Mol. Genet. 15, 1640-1649 (2006).
-
(2006)
Hum. Mol. Genet
, vol.15
, pp. 1640-1649
-
-
Lee, C.R.1
North, K.E.2
Bray, M.S.3
-
59
-
-
1642458135
-
Polymorphism of the soluble epoxide hydrolase is associated with coronary artery calcification in African-American subjects: The Coronary Artery Risk Development in Young Adults (CARDIA) study
-
Fornage M, Boerwinkle E, Doris PA, Jacobs D, Liu K, Wong ND: Polymorphism of the soluble epoxide hydrolase is associated with coronary artery calcification in African-American subjects: the Coronary Artery Risk Development in Young Adults (CARDIA) study. Circulation 109, 335-339 (2004).
-
(2004)
Circulation
, vol.109
, pp. 335-339
-
-
Fornage, M.1
Boerwinkle, E.2
Doris, P.A.3
Jacobs, D.4
Liu, K.5
Wong, N.D.6
-
60
-
-
33845535114
-
Sequence variation in the soluble epoxide hydrolase gene and subclinical coronary atherosclerosis: Interaction with cigarette smoking
-
Wei Q, Doris PA, Pollizotto MV et al.: Sequence variation in the soluble epoxide hydrolase gene and subclinical coronary atherosclerosis: interaction with cigarette smoking. Atherosclerosis 190, 26-34 (2007).
-
(2007)
Atherosclerosis
, vol.190
, pp. 26-34
-
-
Wei, Q.1
Doris, P.A.2
Pollizotto, M.V.3
-
61
-
-
26444506849
-
The soluble epoxide hydrolase gene harbors sequence variation associated with susceptibility to and protection from incident ischemic stroke
-
Fornage M, Lee CR, Doris PA et al.: The soluble epoxide hydrolase gene harbors sequence variation associated with susceptibility to and protection from incident ischemic stroke. Hum. Mol. Genet. 14, 2829-2837 (2005).
-
(2005)
Hum. Mol. Genet
, vol.14
, pp. 2829-2837
-
-
Fornage, M.1
Lee, C.R.2
Doris, P.A.3
-
62
-
-
10744225519
-
Soluble epoxide hydrolase variant (Glu287Arg) modifies plasma total cholesterol and triglyceride phenotype in familial hypercholesterolemia: Intrafamilial association study in an eight-generation hyperlipidemic kindred
-
Sato K, Emi M, Ezura Y et al.: Soluble epoxide hydrolase variant (Glu287Arg) modifies plasma total cholesterol and triglyceride phenotype in familial hypercholesterolemia: intrafamilial association study in an eight-generation hyperlipidemic kindred. J. Hum. Genet. 49, 29-34 (2004).
-
(2004)
J. Hum. Genet
, vol.49
, pp. 29-34
-
-
Sato, K.1
Emi, M.2
Ezura, Y.3
-
63
-
-
17444380409
-
Association of soluble epoxide hydrolase gene polymorphism with insulin resistance in Type 2 diabetic patients
-
Ohtoshi K, Kaneto H, Node K et al.: Association of soluble epoxide hydrolase gene polymorphism with insulin resistance in Type 2 diabetic patients. Biochem. Biophys. Res. Commun. 331, 347-350 (2005).
-
(2005)
Biochem. Biophys. Res. Commun
, vol.331
, pp. 347-350
-
-
Ohtoshi, K.1
Kaneto, H.2
Node, K.3
-
64
-
-
34249997024
-
Replicating genotype-phenotype associations
-
Chanock SJ, Manolio T, Boehnke M et al.: Replicating genotype-phenotype associations. Nature 447, 655-660 (2007).
-
(2007)
Nature
, vol.447
, pp. 655-660
-
-
Chanock, S.J.1
Manolio, T.2
Boehnke, M.3
-
65
-
-
0037426052
-
Problems of reporting genetic associations with complex outcomes
-
Colhoun HM, McKeigue PM, Davey Smith G: Problems of reporting genetic associations with complex outcomes. Lancet 361, 865-872 (2003).
-
(2003)
Lancet
, vol.361
, pp. 865-872
-
-
Colhoun, H.M.1
McKeigue, P.M.2
Davey Smith, G.3
-
66
-
-
0742288585
-
The complex interplay among factors that influence allelic association
-
Zondervan KT, Cardon LR: The complex interplay among factors that influence allelic association. Nat. Rev. Genet. 5, 89-100 (2004).
-
(2004)
Nat. Rev. Genet
, vol.5
, pp. 89-100
-
-
Zondervan, K.T.1
Cardon, L.R.2
-
67
-
-
33745017730
-
ACE polymorphisms
-
Sayed-Tabatabaei FA, Oostra BA, Isaacs A, van Duijn CM, Witteman JC: ACE polymorphisms. Circ. Res. 98, 1123-1133 (2006).
-
(2006)
Circ. Res
, vol.98
, pp. 1123-1133
-
-
Sayed-Tabatabaei, F.A.1
Oostra, B.A.2
Isaacs, A.3
van Duijn, C.M.4
Witteman, J.C.5
-
68
-
-
33750903351
-
Endothelial nitric oxide synthase gene polymorphisms and cardiovascular disease: A HuGE review
-
Casas JP, Cavalleri GL, Bautista LE, Smeeth L, Humphries SE, Hingorani AD: Endothelial nitric oxide synthase gene polymorphisms and cardiovascular disease: a HuGE review. Am. J. Epidemiol. 164, 921-935 (2006).
-
(2006)
Am. J. Epidemiol
, vol.164
, pp. 921-935
-
-
Casas, J.P.1
Cavalleri, G.L.2
Bautista, L.E.3
Smeeth, L.4
Humphries, S.E.5
Hingorani, A.D.6
-
69
-
-
33747594330
-
Cardiac adrenoceptors: Physiological and pathophysiological relevance
-
Brodde OE, Bruck H, Leineweber K: Cardiac adrenoceptors: physiological and pathophysiological relevance. J. Pharmacol. Sci. 100, 323-337 (2006).
-
(2006)
J. Pharmacol. Sci
, vol.100
, pp. 323-337
-
-
Brodde, O.E.1
Bruck, H.2
Leineweber, K.3
-
70
-
-
2942610581
-
Dysfunction of endothelial nitric oxide synthase and atherosclerosis
-
Kawashima S, Yokoyama M: Dysfunction of endothelial nitric oxide synthase and atherosclerosis. Arterioscler. Thromb. Vasc. Biol. 24, 998-1005 (2004).
-
(2004)
Arterioscler. Thromb. Vasc. Biol
, vol.24
, pp. 998-1005
-
-
Kawashima, S.1
Yokoyama, M.2
-
71
-
-
2442547743
-
The pathophysiology of cigarette smoking and cardiovascular disease: An update
-
Ambrose JA, Barua RS: The pathophysiology of cigarette smoking and cardiovascular disease: an update. J. Am. Coll. Cardiol. 43, 1731-1737 (2004).
-
(2004)
J. Am. Coll. Cardiol
, vol.43
, pp. 1731-1737
-
-
Ambrose, J.A.1
Barua, R.S.2
-
72
-
-
34247867952
-
Cardiovascular therapeutic aspects of soluble-epoxide hydrolase inhibitors
-
Imig JD: Cardiovascular therapeutic aspects of soluble-epoxide hydrolase inhibitors. Cardiovasc. Drug Rev. 24, 169-188 (2006).
-
(2006)
Cardiovasc. Drug Rev
, vol.24
, pp. 169-188
-
-
Imig, J.D.1
-
73
-
-
0024591825
-
The Atherosclerosis Risk in Communities (ARIC) Study: Design and objectives
-
The ARIC Investigators
-
The ARIC Investigators: The Atherosclerosis Risk in Communities (ARIC) Study: design and objectives. Am. J. Epidemiol. 129, 687-702 (1989).
-
(1989)
Am. J. Epidemiol
, vol.129
, pp. 687-702
-
-
|