-
1
-
-
0026778133
-
The small GTP-binding protein Rho regulates the assembly of focal adhesions and actin stress fibers in response to growth-factors
-
Ridley A J, Hall A. The small GTP-binding protein Rho regulates the assembly of focal adhesions and actin stress fibers in response to growth-factors. Cell, 1992, 70: 389-399
-
(1992)
Cell
, vol.70
, pp. 389-399
-
-
Ridley, A.J.1
Hall, A.2
-
2
-
-
0026654125
-
The small GTP-binding protein Rac regulates growthfactor induced membrane ruffling
-
Ridley A J, Paterson H F, Johnston C L, et al. The small GTP-binding protein Rac regulates growthfactor induced membrane ruffling. Cell, 1992, 70: 401-410
-
(1992)
Cell
, vol.70
, pp. 401-410
-
-
Ridley, A.J.1
Paterson, H.F.2
Johnston, C.L.3
-
3
-
-
0037069690
-
Rho GTPases in cell biology
-
Etienne-Manneville S, Hall A. Rho GTPases in cell biology. Nature, 2002, 420: 629-635
-
(2002)
Nature
, vol.420
, pp. 629-635
-
-
Etienne-Manneville, S.1
Hall, A.2
-
4
-
-
0033838716
-
Regulation of cell function by Rho family GTPases
-
Bokoch G M. Regulation of cell function by Rho family GTPases. Immunol Res, 2002, 21: 139-148
-
(2002)
Immunol Res
, vol.21
, pp. 139-148
-
-
Bokoch, G.M.1
-
5
-
-
0028961293
-
Rho, Rac, and Cdc42 GTPases regulate the assembly of multimolecular focal complexes associated with actin stress fibers, lamellipodia, and filopodia
-
Nobes C D, Hall A. Rho, Rac, and Cdc42 GTPases regulate the assembly of multimolecular focal complexes associated with actin stress fibers, lamellipodia, and filopodia. Cell, 1995, 81: 53-62
-
(1995)
Cell
, vol.81
, pp. 53-62
-
-
Nobes, C.D.1
Hall, A.2
-
6
-
-
0032489841
-
A new member of the Rho family, Rnd1, promotes disassembly of actin filament structures and loss of cell adhesion
-
Nobes C D, Lauritzen I, Mattei M G, et al. A new member of the Rho family, Rnd1, promotes disassembly of actin filament structures and loss of cell adhesion. J Cell BioL, 1998, 141: 187-197
-
(1998)
J Cell BioL
, vol.141
, pp. 187-197
-
-
Nobes, C.D.1
Lauritzen, I.2
Mattei, M.G.3
-
7
-
-
0842281652
-
Rho and Rac take center stage
-
Keith B, Krister W. Rho and Rac take center stage. Cell, 2004, 116: 167-179
-
(2004)
Cell
, vol.116
, pp. 167-179
-
-
Keith, B.1
Krister, W.2
-
8
-
-
2342418629
-
Rho-family GTPases: It's not only Rac and Rho (and i like it)
-
Wennerberg K, Der C J. Rho-family GTPases: It's not only Rac and Rho (and I like it). J Cell Sci, 2004, 117: 1301-1312
-
(2004)
J Cell Sci
, vol.117
, pp. 1301-1312
-
-
Wennerberg, K.1
Der, C.J.2
-
9
-
-
27944479854
-
Rho GTPase: Biochemistry and biology
-
Jaffe A B, Hall A. Rho GTPase: Biochemistry and biology. Annu Rev Cell Dev Biol, 2005, 21: 247-269
-
(2005)
Annu Rev Cell Dev Biol
, vol.21
, pp. 247-269
-
-
Jaffe, A.B.1
Hall, A.2
-
10
-
-
27644520496
-
Cytokinesis: Rho marks the spot
-
Patricia W. Cytokinesis: Rho marks the spot. Curr Biol, 2005, 15: 871-874
-
(2005)
Curr Biol
, vol.15
, pp. 871-874
-
-
Patricia, W.1
-
12
-
-
13444252631
-
GEF means go: Turning on RHO GTPases with guanine nucleotide-exchange factors
-
2
-
Rossman K L, Der C J, Sondek J. GEF means go: turning on RHO GTPases with guanine nucleotide-exchange factors. Nat Rev Mol Cell Biol, 2005, 6(2): 167-180
-
(2005)
Nat Rev Mol Cell Biol
, vol.6
, pp. 167-180
-
-
Rossman, K.L.1
Der, C.J.2
Sondek, J.3
-
13
-
-
0033636507
-
The adhesion signaling molecule p190 RhoGAP is required for morphogenetic processes in neural development
-
Madelein R B, Stephen F M, Hu K Q, et al. The adhesion signaling molecule p190 RhoGAP is required for morphogenetic processes in neural development. Development, 2000, 127: 4891-4903
-
(2000)
Development
, vol.127
, pp. 4891-4903
-
-
Madelein, R.B.1
Stephen, F.M.2
Hu, K.Q.3
-
14
-
-
0038517913
-
P190-B RhoGAP regulates mammary ductal morphogenesis
-
Chakravarty G, Hadsell D, Buitrago W, et al. P190-B RhoGAP regulates mammary ductal morphogenesis. Mol Endo, 2003, 17: 1054-1065
-
(2003)
Mol Endo
, vol.17
, pp. 1054-1065
-
-
Chakravarty, G.1
Hadsell, D.2
Buitrago, W.3
-
15
-
-
24944582633
-
GAPs in growth factor signaling
-
Bernards A, Settleman J. GAPs in growth factor signaling. Growth Factors, 2005, 23: 143-149
-
(2005)
Growth Factors
, vol.23
, pp. 143-149
-
-
Bernards, A.1
Settleman, J.2
-
16
-
-
0034213327
-
Rho GTPases and their effector proteins
-
2
-
Bishop A L, Hall A. Rho GTPases and their effector proteins. J Biochem, 2000, 348(2): 241-255
-
(2000)
J Biochem
, vol.348
, pp. 241-255
-
-
Bishop, A.L.1
Hall, A.2
-
17
-
-
0035756318
-
Structure of small G proteins and their regulators
-
Paduch M, Jelen F, Otlewski J. Structure of small G proteins and their regulators. Acta Biochim Pol, 2001, 48: 829-850
-
(2001)
Acta Biochim Pol
, vol.48
, pp. 829-850
-
-
Paduch, M.1
Jelen, F.2
Otlewski, J.3
-
18
-
-
33646927812
-
Mechanisms of self-renewal in human embryonic stem cells
-
Stewart R, Stojkovic M, Lako M. Mechanisms of self-renewal in human embryonic stem cells. Eur J Cancer, 2006, 42: 1257-1272
-
(2006)
Eur J Cancer
, vol.42
, pp. 1257-1272
-
-
Stewart, R.1
Stojkovic, M.2
Lako, M.3
-
19
-
-
33645518250
-
Mesenchymal stem cells and bone regeneration
-
Kraus K H, Kirker-head C. Mesenchymal stem cells and bone regeneration. Vet Surg, 2006, 35: 232-242
-
(2006)
Vet Surg
, vol.35
, pp. 232-242
-
-
Kraus, K.H.1
Kirker-Head, C.2
-
20
-
-
33747584117
-
Human embryonic stem cell: Isolation, maintenance, and differentiation
-
Turksen K, Troy T C. Human embryonic stem cell: Isolation, maintenance, and differentiation. Methods Mol Biol, 2006, 331: 1-12
-
(2006)
Methods Mol Biol
, vol.331
, pp. 1-12
-
-
Turksen, K.1
Troy, T.C.2
-
21
-
-
33644804669
-
Neural stem cells: On where they hide, in which disguise, and how we may lure them out
-
Berninger B, Hack M A, Gotz M. Neural stem cells: on where they hide, in which disguise, and how we may lure them out. Handb Exp Pharmacol, 2006, 174: 319-360
-
(2006)
Handb Exp Pharmacol
, vol.174
, pp. 319-360
-
-
Berninger, B.1
Hack, M.A.2
Gotz, M.3
-
22
-
-
33645103515
-
The hematopoietic stem cell in its place
-
Adams G B, Scadden D T. The hematopoietic stem cell in its place. Nat Immunol, 2006, 7: 333-337
-
(2006)
Nat Immunol
, vol.7
, pp. 333-337
-
-
Adams, G.B.1
Scadden, D.T.2
-
23
-
-
33644858630
-
Rho GTPases in animal cell mitosis
-
Shuh N, Shingo Y. Rho GTPases in animal cell mitosis. Curr Opin Cell Biol, 2006, 18: 199-205
-
(2006)
Curr Opin Cell Biol
, vol.18
, pp. 199-205
-
-
Shuh, N.1
Shingo, Y.2
-
25
-
-
0033768115
-
Essential roles of Drosophila RhoA in the regulation of neuroblast proliferation and dendritic but not axonal morphogenesis
-
Tzumin L, Christopher W, Simone S, et al. Essential roles of Drosophila RhoA in the regulation of neuroblast proliferation and dendritic but not axonal morphogenesis. Neuron, 2000, 25: 307-316
-
(2000)
Neuron
, vol.25
, pp. 307-316
-
-
Tzumin, L.1
Christopher, W.2
Simone, S.3
-
26
-
-
1642580743
-
Involvement of Rho Family GTPases in p19Arf-and p53-mediated proliferation of primary mouse embryonic fibroblasts
-
Guo F, Zheng Y. Involvement of Rho Family GTPases in p19Arf-and p53-mediated proliferation of primary mouse embryonic fibroblasts. Mol Cell Bio, 2004, 3: 1426-1438
-
(2004)
Mol Cell Bio
, vol.3
, pp. 1426-1438
-
-
Guo, F.1
Zheng, Y.2
-
27
-
-
33748703837
-
Inhibition of RhoA GTPase activity enhances hematopoietic stem and progenitor cell proliferation and engraftment
-
Gabriel G, Andrew L, Jeff B, et al. Inhibition of RhoA GTPase activity enhances hematopoietic stem and progenitor cell proliferation and engraftment. Blood, 2006, 108: 2087-2094
-
(2006)
Blood
, vol.108
, pp. 2087-2094
-
-
Gabriel, G.1
Andrew, L.2
Jeff, B.3
-
28
-
-
15544385625
-
Rac2-Deficient hematopoietic stem cells show defective interaction with the hematopoietic microenvironment and long-term engraftment failure
-
3
-
Jansen M, Yang F C, Cancelas J A, et al. Rac2-Deficient hematopoietic stem cells show defective interaction with the hematopoietic microenvironment and long-term engraftment failure. Stem Cells, 2005, 23(3): 335-346
-
(2005)
Stem Cells
, vol.23
, pp. 335-346
-
-
Jansen, M.1
Yang, F.C.2
Cancelas, J.A.3
-
29
-
-
13544249617
-
RhoH, a hematopoietic-specific Rho GTPase, regulates proliferation, survival, migration and engraftment of hematopoietic progenitor cells
-
Gu Y, Jasti A C, Jansen M, et al. RhoH, a hematopoietic-specific Rho GTPase, regulates proliferation, survival, migration and engraftment of hematopoietic progenitor cells. Blood, 2005, 105: 1467-1475
-
(2005)
Blood
, vol.105
, pp. 1467-1475
-
-
Gu, Y.1
Jasti, A.C.2
Jansen, M.3
-
30
-
-
25444476956
-
RhoH GTPase: A key regulator of hematopoietic cell proliferation and apoptosis
-
2
-
Gu Y, Zheng Y, Williams D A. RhoH GTPase: A key regulator of hematopoietic cell proliferation and apoptosis? Cell Cycle, 2005, 4(2): 201-202
-
(2005)
Cell Cycle
, vol.4
, pp. 201-202
-
-
Gu, Y.1
Zheng, Y.2
Williams, D.A.3
-
31
-
-
0035463289
-
Rac'n Rho: The music that shapes a developing embryo
-
Settleman J. Rac'n Rho: The music that shapes a developing embryo. Dev Cell, 2001, 1: 321-331
-
(2001)
Dev Cell
, vol.1
, pp. 321-331
-
-
Settleman, J.1
-
32
-
-
18444411005
-
Modulation of CREB activity by the Rho GTPase regulates cell and organism size during mouse embryonic development
-
Sordella R, Classon M, Hu K Q, et al. Modulation of CREB activity by the Rho GTPase regulates cell and organism size during mouse embryonic development. Dev Cell, 2002, 2: 553-565
-
(2002)
Dev Cell
, vol.2
, pp. 553-565
-
-
Sordella, R.1
Classon, M.2
Hu, K.Q.3
-
33
-
-
0037453716
-
Modulation of Rho GTPase signaling regulates a switch between adipogenesis and myogenesis
-
Sordella R, Jiang W, Chen G C, et al. Modulation of Rho GTPase signaling regulates a switch between adipogenesis and myogenesis. Cell, 2003, 113: 147-158
-
(2003)
Cell
, vol.113
, pp. 147-158
-
-
Sordella, R.1
Jiang, W.2
Chen, G.C.3
-
34
-
-
1542358860
-
Direct cell contact influences bone marrow mesenchymal stem cell fate
-
Ball S G, Shuttleworth A C, Kielty C M. Direct cell contact influences bone marrow mesenchymal stem cell fate. J Biochem Cell Biol, 2004, 36: 714-727
-
(2004)
J Biochem Cell Biol
, vol.36
, pp. 714-727
-
-
Ball, S.G.1
Shuttleworth, A.C.2
Kielty, C.M.3
-
35
-
-
1842426730
-
Cell shape, cytoskeletal tension, and RhoA regulate stem cell lineage commitment
-
McBeath R, Pirone D M, Nelson C M, et al. Cell shape, cytoskeletal tension, and RhoA regulate stem cell lineage commitment. Dev Cell, 2004, 6: 483-495
-
(2004)
Dev Cell
, vol.6
, pp. 483-495
-
-
Pirone, D.M.1
Nelson, C.M.2
-
36
-
-
0037018153
-
High RhoA activity maintains the undifferentiated mesenchymal cell phenotype, whereas RhoA down-regulation by laminin-2 induces smooth muscle myogenesis
-
Beqaj S, Jakkaraju S, Mattingly RR, et al. High RhoA activity maintains the undifferentiated mesenchymal cell phenotype, whereas RhoA down-regulation by laminin-2 induces smooth muscle myogenesis. J Cell Biol, 2002, 156: 893-903
-
(2002)
J Cell Biol
, vol.156
, pp. 893-903
-
-
Beqaj, S.1
Jakkaraju, S.2
Mattingly, R.R.3
-
37
-
-
0034267997
-
Molecular mechanisms regulate myogenic determination and differentiation
-
Perry R L, Rudnick M A. Molecular mechanisms regulate myogenic determination and differentiation. Front Biosci. 2000, 5: 750-767
-
(2000)
Front Biosci
, vol.5
, pp. 750-767
-
-
Perry, R.L.1
Rudnick, M.A.2
-
38
-
-
22544485397
-
The Rho family of small GTPases: Crucial regulators of skeletal myogenesis
-
Bryan B A, Li D, Wu X, et al. The Rho family of small GTPases: crucial regulators of skeletal myogenesis. CMLS-Cell Mol Life Sci, 2005, 62: 1-9
-
(2005)
CMLS-Cell Mol Life Sci
, vol.62
, pp. 1-9
-
-
Bryan, B.A.1
Li, D.2
Wu, X.3
-
39
-
-
11844285639
-
Cytotoxic necrotizing factor 1 hinders skeletal muscle differentiation in vitro by perturbing the activation/deactivation balance of Rho GTPases
-
Travaglione S, Messina G, Fabbri A, et al. Cytotoxic necrotizing factor 1 hinders skeletal muscle differentiation in vitro by perturbing the activation/deactivation balance of Rho GTPases. Cell Death Differ, 2005, 12: 78-86
-
(2005)
Cell Death Differ
, vol.12
, pp. 78-86
-
-
Travaglione, S.1
Messina, G.2
Fabbri, A.3
-
40
-
-
0028829750
-
The Rho's progress: A potential role during neuritogenesis for the Rho family of GTPases
-
Mackay D J G, Nobes C D, Hall A. The Rho's progress: A potential role during neuritogenesis for the Rho family of GTPases. Trends Neurosci, 1995, 18: 496-501
-
(1995)
Trends Neurosci
, vol.18
, pp. 496-501
-
-
MacKay, D.J.G.1
Nobes, C.D.2
Hall, A.3
-
41
-
-
11844304062
-
The role of the Rho GTPases in neuronal development
-
1
-
Govek E, Newey S E, Aelst L V. The role of the Rho GTPases in neuronal development. Genens Dev, 2005, 19(1): 1-49
-
(2005)
Genens Dev
, vol.19
, pp. 1-49
-
-
Govek, E.1
Newey, S.E.2
Aelst, L.V.3
-
42
-
-
8744224517
-
Inactivation of Rho/ROCK signaling is crucial for the muclear accumulation of FKHR and myoblast fusion
-
Nishiyama T, Kii I, Kudo A. Inactivation of Rho/ROCK signaling is crucial for the muclear accumulation of FKHR and myoblast fusion. J Biol Chem, 2004, 279: 47311-47319
-
(2004)
J Biol Chem
, vol.279
, pp. 47311-47319
-
-
Nishiyama, T.1
Kii, I.2
Kudo, A.3
-
43
-
-
0034883426
-
Rho kinases play an obligatory role in vertebrate embryonic organogenesis
-
Wei L, Roberts W, Wang L, et al. Rho kinases play an obligatory role in vertebrate embryonic organogenesis. Dev, 2001, 128: 2953-2962
-
(2001)
Dev
, vol.128
, pp. 2953-2962
-
-
Wei, L.1
Roberts, W.2
Wang, L.3
-
44
-
-
31944439553
-
Coupling of cell migration with neurogenesis by proneural bHLH factors
-
Weihong G, Fei H, Kevin J K, et al. Coupling of cell migration with neurogenesis by proneural bHLH factors. Proc Natl Acad Sci USA, 2006, 103: 1319-1324
-
(2006)
Proc Natl Acad Sci USA
, vol.103
, pp. 1319-1324
-
-
Weihong, G.1
Fei, H.2
Kevin, J.K.3
-
46
-
-
0036720830
-
The TRQQKPP motif located near the C-terminus of Rac2 is essential for Rac2 biologic functions and intracellular localization
-
Tao W, Filippi M D, Bailey J R, et al. The TRQQKPP motif located near the C-terminus of Rac2 is essential for Rac2 biologic functions and intracellular localization. Blood, 2002, 100: 1679-1688
-
(2002)
Blood
, vol.100
, pp. 1679-1688
-
-
Tao, W.1
Filippi, M.D.2
Bailey, J.R.3
-
47
-
-
33746073002
-
The role of chemokine activation of Rac GTPases in hematopoietic stem cell marrow homing, retention, and peripheral mobilization
-
Cancelas J A, Jansen M, Wiliams D A. The role of chemokine activation of Rac GTPases in hematopoietic stem cell marrow homing, retention, and peripheral mobilization. Exp Hematol, 2006, 34: 976-985
-
(2006)
Exp Hematol
, vol.34
, pp. 976-985
-
-
Cancelas, J.A.1
Jansen, M.2
Wiliams, D.A.3
-
48
-
-
0035826843
-
Rac and Cdc42 GTPases control hematopoietic stem cell shape, adhesion, migration, and mobilization
-
Yang F C, Atkinson S J, Gu Y, et al. Rac and Cdc42 GTPases control hematopoietic stem cell shape, adhesion, migration, and mobilization. Proc Natl Acad Sci USA. 2001, 98: 5614-5618
-
(2001)
Proc Natl Acad Sci USA
, vol.98
, pp. 5614-5618
-
-
Yang, F.C.1
Atkinson, S.J.2
Gu, Y.3
-
49
-
-
30144446099
-
Genetic deletion of Cdc42GAP reveals a role of Cdc42 in erythropoiesis and hematopoietic stem/progenitor cell survival adhesion, and engraftment
-
Wang L, Yang L, Filippi M D, et al. Genetic deletion of Cdc42GAP reveals a role of Cdc42 in erythropoiesis and hematopoietic stem/progenitor cell survival adhesion, and engraftment. Blood, 2006, 107: 98-105
-
(2006)
Blood
, vol.107
, pp. 98-105
-
-
Wang, L.1
Yang, L.2
Filippi, M.D.3
-
50
-
-
33646941002
-
Therapeutic potential of adult stem cells
-
Serakinci N, Keith W N. Therapeutic potential of adult stem cells. Eur J Cancer, 2006, 9: 1243-1246
-
(2006)
Eur J Cancer
, vol.9
, pp. 1243-1246
-
-
Serakinci, N.1
Keith, W.N.2
-
51
-
-
33745684551
-
The therapeutic potential of neural stem cells
-
Martino G, Pluchino S. the therapeutic potential of neural stem cells. Nat Rev Neurosci, 2006, 7: 395-406
-
(2006)
Nat Rev Neurosci
, vol.7
, pp. 395-406
-
-
Martino, G.1
Pluchino, S.2
-
52
-
-
33744551726
-
Stem cells: Potential therapy for age-related diseases
-
Kassem M. Stem cells: Potential therapy for age-related diseases. Ann N Y Acad Sci, 2006, 1067: 436-442
-
(2006)
Ann N y Acad Sci
, vol.1067
, pp. 436-442
-
-
Kassem, M.1
-
53
-
-
33745601099
-
Stem cells for the treatment of neurological disorders
-
Lindvall O, Kokaia Z. Stem cells for the treatment of neurological disorders. Nature, 2006, 441: 1094-1096
-
(2006)
Nature
, vol.441
, pp. 1094-1096
-
-
Lindvall, O.1
Kokaia, Z.2
-
54
-
-
33745628337
-
Potential of stem-cell-related therapies for heart disease
-
Sirvastava D, Ivey K N. Potential of stem-cell-related therapies for heart disease. Nature, 2006, 441: 1097-1099
-
(2006)
Nature
, vol.441
, pp. 1097-1099
-
-
Sirvastava, D.1
Ivey, K.N.2
-
55
-
-
33747065888
-
Delivering cancer stem cell therapies-a role for nanomedicines
-
Schatzleon A G. Delivering cancer stem cell therapies-a role for nanomedicines. Eur J Cancer, 2006, 9: 1309-1315
-
(2006)
Eur J Cancer
, vol.9
, pp. 1309-1315
-
-
Schatzleon, A.G.1
-
56
-
-
33747173765
-
Gene therapy for glioblastoma
-
Aghi M, Chiocca E A. Gene therapy for glioblastoma. Neurosurg Focus, 2006, 20: E18
-
(2006)
Neurosurg Focus
, vol.20
, pp. 18
-
-
Aghi, M.1
Chiocca, E.A.2
-
57
-
-
33747076690
-
Neural stem cells as novel cancer therapeutic vehicles
-
Yip S, Sabetrasekh R, Sidman R L, et al. Neural stem cells as novel cancer therapeutic vehicles. Eur J Cancer, 2006, 42: 1298-1308
-
(2006)
Eur J Cancer
, vol.42
, pp. 1298-1308
-
-
Yip, S.1
Sabetrasekh, R.2
Sidman, R.L.3
-
58
-
-
23644453653
-
Rho kinase as potential therapeutic target for cardiovascular diseases: Opportunities and challenges
-
Hu E, Lee D. Rho kinase as potential therapeutic target for cardiovascular diseases: Opportunities and challenges. Expert Opin Ther Targets, 2005, 4: 715-736
-
(2005)
Expert Opin Ther Targets
, vol.4
, pp. 715-736
-
-
Hu, E.1
Lee, D.2
-
59
-
-
18944372230
-
Rho Kinase, a promising drug target for neurological disorders
-
5
-
Mueller B K, Mack H, Teusch N. Rho Kinase, a promising drug target for neurological disorders. Nat Rev Drug Discov. 2005, 4(5): 387-398
-
(2005)
Nat Rev Drug Discov.
, vol.4
, pp. 387-398
-
-
Mueller, B.K.1
MacK, H.2
Teusch, N.3
|