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Volumn 62, Issue 11, 2007, Pages 813-824

New benzomorphan derivatives of MPCB as MOP and KOP receptor ligands

Author keywords

[No Author keywords available]

Indexed keywords

BENZOMORPHAN DERIVATIVE; KAPPA OPIATE RECEPTOR; MU OPIATE RECEPTOR; TYROSINE;

EID: 36349021861     PISSN: 00317144     EISSN: None     Source Type: Journal    
DOI: 10.1691/ph.2007.11.7523     Document Type: Article
Times cited : (5)

References (33)
  • 1
    • 0023134667 scopus 로고
    • 1-Aril-2-(aminomethyl)cyclopropanecarboxylic acid derivatives. A new series of potential antidepressants
    • Bonnaud B, Cousse H, Mouzin G, Briley M, Stenger A, Fauran F, Couzinier JP (1987) 1-Aril-2-(aminomethyl)cyclopropanecarboxylic acid derivatives. A new series of potential antidepressants. J Med Chem 30: 318-325.
    • (1987) J Med Chem , vol.30 , pp. 318-325
    • Bonnaud, B.1    Cousse, H.2    Mouzin, G.3    Briley, M.4    Stenger, A.5    Fauran, F.6    Couzinier, J.P.7
  • 3
    • 0018128735 scopus 로고
    • Acide phenyl-1-hydroxymethyl-2-cyclopropane carboxylique et derives
    • Casadio S, Bonnaud B, Mouzin G, Cousse H (1978) Acide phenyl-1-hydroxymethyl-2-cyclopropane carboxylique et derives. Boll Chim Farm 117: 331-342.
    • (1978) Boll Chim Farm , vol.117 , pp. 331-342
    • Casadio, S.1    Bonnaud, B.2    Mouzin, G.3    Cousse, H.4
  • 5
    • 33644982587 scopus 로고    scopus 로고
    • Steric interactions and the activity of fentanyl analogs at the μ-opioid receptor
    • Dosen-Micovic L, Ivanovic M, Micovic V (2006) Steric interactions and the activity of fentanyl analogs at the μ-opioid receptor. Bioorg Med Chem 14: 2887-2895.
    • (2006) Bioorg Med Chem , vol.14 , pp. 2887-2895
    • Dosen-Micovic, L.1    Ivanovic, M.2    Micovic, V.3
  • 7
    • 0034632797 scopus 로고    scopus 로고
    • Furness MS, Zhang X, Coop A, Jacobson AE, Rothman RB, Dersch CM, Xu H, Porreca F, Rice KC (2000) Probes for narcotic receptor-mediated phenomena. 27. Synthesis and pharmacological evaluation of selective δ-opioid receptor agonists from 4-[(αR)-α-(2S,5R)-4-substituted- 2,5-dimethyl-1-piperazinyl-3-methoxybenzyl]-N,N-diethylbenzamides and their enantiomers. J Med Chem 43: 3193-3196.
    • Furness MS, Zhang X, Coop A, Jacobson AE, Rothman RB, Dersch CM, Xu H, Porreca F, Rice KC (2000) Probes for narcotic receptor-mediated phenomena. 27. Synthesis and pharmacological evaluation of selective δ-opioid receptor agonists from 4-[(αR)-α-(2S,5R)-4-substituted- 2,5-dimethyl-1-piperazinyl-3-methoxybenzyl]-N,N-diethylbenzamides and their enantiomers. J Med Chem 43: 3193-3196.
  • 9
    • 0031552362 scopus 로고    scopus 로고
    • Development and validation of a genetic algorithm for flexible docking
    • Jones G, Willett P, Glen RC, Leach AR, Taylor R (1997) Development and validation of a genetic algorithm for flexible docking. J Mol Biol 267: 727-748.
    • (1997) J Mol Biol , vol.267 , pp. 727-748
    • Jones, G.1    Willett, P.2    Glen, R.C.3    Leach, A.R.4    Taylor, R.5
  • 10
    • 33646271609 scopus 로고    scopus 로고
    • A unique binding epitope for Salvinorin A, a non-nitrogenous kappa opioid receptor agonist
    • Kane BE, Nieto MJ, McCurdy CR, Ferguson DM (2006) A unique binding epitope for Salvinorin A, a non-nitrogenous kappa opioid receptor agonist. FEBS Journal 273: 1966-1974.
    • (2006) FEBS Journal , vol.273 , pp. 1966-1974
    • Kane, B.E.1    Nieto, M.J.2    McCurdy, C.R.3    Ferguson, D.M.4
  • 11
    • 0028099965 scopus 로고
    • Amino acids in the cloned mouse kappa receptor that are necessary for high affinity agonist binding but not antagonist binding
    • Kong H, Raynor K, Reisine T (1994) Amino acids in the cloned mouse kappa receptor that are necessary for high affinity agonist binding but not antagonist binding. Reg Pept 54: 155-156.
    • (1994) Reg Pept , vol.54 , pp. 155-156
    • Kong, H.1    Raynor, K.2    Reisine, T.3
  • 12
    • 0025855256 scopus 로고
    • The dopamine hypothesis of the reinforcing properties of cocaine
    • Kuhar MJ, Ritz MC, Boja JW (1991) The dopamine hypothesis of the reinforcing properties of cocaine. Trends Neurosci 14: 299-302.
    • (1991) Trends Neurosci , vol.14 , pp. 299-302
    • Kuhar, M.J.1    Ritz, M.C.2    Boja, J.W.3
  • 13
    • 0034214399 scopus 로고    scopus 로고
    • Modeling of κ-opioid receptor/agonists interactions using pharmacophore-based and docking simulations
    • Lavecchia A, Greco G, Novellino E, Vittorio F, Ronsisvalle G (2000) Modeling of κ-opioid receptor/agonists interactions using pharmacophore-based and docking simulations. J Med Chem 43: 2124-2134.
    • (2000) J Med Chem , vol.43 , pp. 2124-2134
    • Lavecchia, A.1    Greco, G.2    Novellino, E.3    Vittorio, F.4    Ronsisvalle, G.5
  • 14
    • 0242610916 scopus 로고    scopus 로고
    • κ-Opioid agonists directly inhibit midbrain dopaminergic neurons
    • Margolis EB, Hjelmstad GO, Bonci A, Fields HL (2003) κ-Opioid agonists directly inhibit midbrain dopaminergic neurons. J Neurosci 23: 9981-9986.
    • (2003) J Neurosci , vol.23 , pp. 9981-9986
    • Margolis, E.B.1    Hjelmstad, G.O.2    Bonci, A.3    Fields, H.L.4
  • 15
    • 0036168685 scopus 로고    scopus 로고
    • Synthesis of (+)- and (-)-cis-2-[(1-adamantylamino) -methyl]-1-phenylcyclopropane derivatives as high affinity probes for σ1 and σ2 binding sites
    • Marrazzo A, Prezzavento O, Pappalardo MS, Bousquet E, Iadanza M, Pike VW, Ronsisvalle G (2002) Synthesis of (+)- and (-)-cis-2-[(1-adamantylamino) -methyl]-1-phenylcyclopropane derivatives as high affinity probes for σ1 and σ2 binding sites. Il Farmaco 57: 45-53.
    • (2002) Il Farmaco , vol.57 , pp. 45-53
    • Marrazzo, A.1    Prezzavento, O.2    Pappalardo, M.S.3    Bousquet, E.4    Iadanza, M.5    Pike, V.W.6    Ronsisvalle, G.7
  • 16
    • 0022005744 scopus 로고
    • Analysis of radioligand binding experiments. A collection of computer programs for the IBM PC
    • McPherson GA (1985) Analysis of radioligand binding experiments. A collection of computer programs for the IBM PC. J Pharmacol Methods 14: 213-228.
    • (1985) J Pharmacol Methods , vol.14 , pp. 213-228
    • McPherson, G.A.1
  • 17
    • 0025141368 scopus 로고
    • κ-Opioid receptors and analgesia
    • Millan MJ (1990) κ-Opioid receptors and analgesia. Trends Pharmacol Sci 11: 70-76.
    • (1990) Trends Pharmacol Sci , vol.11 , pp. 70-76
    • Millan, M.J.1
  • 18
    • 0035935189 scopus 로고    scopus 로고
    • Mixed κ agonists and μ agonists/antagonists as potential pharmacotherapeutics for cocaine abuse: Synthesis and opioid receptor binding affinity of N-substituted derivatives of morphinan
    • Neumeyer JL, Gu XH, van Vliet LA, DeNunzio NJ, Rusovici DE, Cohen DJ, Negus SS, Mello NK, Bidlack JM (2001) Mixed κ agonists and μ agonists/antagonists as potential pharmacotherapeutics for cocaine abuse: synthesis and opioid receptor binding affinity of N-substituted derivatives of morphinan. Bioorg Med Chem Lett 11: 2735-2740.
    • (2001) Bioorg Med Chem Lett , vol.11 , pp. 2735-2740
    • Neumeyer, J.L.1    Gu, X.H.2    van Vliet, L.A.3    DeNunzio, N.J.4    Rusovici, D.E.5    Cohen, D.J.6    Negus, S.S.7    Mello, N.K.8    Bidlack, J.M.9
  • 19
    • 30644458763 scopus 로고    scopus 로고
    • Homology modelling of opioid receptor-ligand complexes using experimental constraints
    • Pogozheva ID, Przydzial MJ, Mosberg HI (2005) Homology modelling of opioid receptor-ligand complexes using experimental constraints. The AAPS Journal 7: E434-E448.
    • (2005) The AAPS Journal , vol.7
    • Pogozheva, I.D.1    Przydzial, M.J.2    Mosberg, H.I.3
  • 20
    • 33646661816 scopus 로고    scopus 로고
    • κ Opioids as potential treatments for stimulant dependence
    • Prisinzano TE, Tidgewell K, Harding WW (2005) κ Opioids as potential treatments for stimulant dependence. AAPS Journal 7: E592-E599.
    • (2005) AAPS Journal , vol.7
    • Prisinzano, T.E.1    Tidgewell, K.2    Harding, W.W.3
  • 21
  • 26
    • 0035272931 scopus 로고    scopus 로고
    • Ronsisvalle G, Marrazzo A, Pasquinucci L, Prezzavento O, Pappalardo MS, Vittorio F (2001) Specific κ opioid receptor agonists. Farmaco 56: 121-125 (Proceedings of the XVIth International Symposium on Medicinal Chemistry, Bologna, Italy, September 18-22, 2000).
    • Ronsisvalle G, Marrazzo A, Pasquinucci L, Prezzavento O, Pappalardo MS, Vittorio F (2001) Specific κ opioid receptor agonists. Farmaco 56: 121-125 (Proceedings of the XVIth International Symposium on Medicinal Chemistry, Bologna, Italy, September 18-22, 2000).
  • 27
    • 34249277652 scopus 로고    scopus 로고
    • A combined ligand-based and target-based drug design approach for G-protein coupled receptors: Application to salvinorin A, a selective kappa opioid receptor agonist
    • Singh N, Chevé G, Ferguson DM, McCurdy CR (2006) A combined ligand-based and target-based drug design approach for G-protein coupled receptors: application to salvinorin A, a selective kappa opioid receptor agonist. J Comput Aided Mol Des 20: 471-493.
    • (2006) J Comput Aided Mol Des , vol.20 , pp. 471-493
    • Singh, N.1    Chevé, G.2    Ferguson, D.M.3    McCurdy, C.R.4
  • 28
    • 0030040736 scopus 로고    scopus 로고
    • Conformational restriction by repulsion between adjacent substituents on a cyclopropane ring: Design and enatioselective synthesis of 1-phenyl-2-(1-aminoalkyl)-N,N-diethylcyclopropanecarboxamides as potent NMDA receptor antagonist
    • Shuto S, Ono S, Hase Y, Kamiyama N, Takada H, Yamasihita K, Matsuda A (1996) Conformational restriction by repulsion between adjacent substituents on a cyclopropane ring: design and enatioselective synthesis of 1-phenyl-2-(1-aminoalkyl)-N,N-diethylcyclopropanecarboxamides as potent NMDA receptor antagonist. J Org Chem 61: 915-923.
    • (1996) J Org Chem , vol.61 , pp. 915-923
    • Shuto, S.1    Ono, S.2    Hase, Y.3    Kamiyama, N.4    Takada, H.5    Yamasihita, K.6    Matsuda, A.7
  • 29
    • 0028170438 scopus 로고
    • μ Opiate receptor. Charged transmembrane domain amino acids are critical for agonist recognition and intrinsic activity
    • Surratt CK, Johnson PS, Moriwaki A, Seidleck BK, Blaschak CJ, Wang JB, Uhl GR (1994) μ Opiate receptor. Charged transmembrane domain amino acids are critical for agonist recognition and intrinsic activity. J Biol Chem 269: 20548-20553.
    • (1994) J Biol Chem , vol.269 , pp. 20548-20553
    • Surratt, C.K.1    Johnson, P.S.2    Moriwaki, A.3    Seidleck, B.K.4    Blaschak, C.J.5    Wang, J.B.6    Uhl, G.R.7
  • 31
    • 0023678336 scopus 로고
    • Kappa receptor regulation of dopamine release from striatum and cortex of rats and guinea pigs
    • Werling L, Frattali A, Portoghese PS, Takemori A, Cox B (1988) Kappa receptor regulation of dopamine release from striatum and cortex of rats and guinea pigs. J Pharmacol Exp Ther 246: 282-286.
    • (1988) J Pharmacol Exp Ther , vol.246 , pp. 282-286
    • Werling, L.1    Frattali, A.2    Portoghese, P.S.3    Takemori, A.4    Cox, B.5
  • 33
    • 0347991961 scopus 로고    scopus 로고
    • 10-Ketomorphinan and 3-substituted-3-desoxymorphinan analogues as mixed κ and μ opioid ligands: Synthesis and biological evaluation of their binding affinity at opioid receptors
    • Zhang A, Xiong W, Bidlack JM, Hilbert JE, Knapp BI, Wentland MP, Neumeyer JL (2004) 10-Ketomorphinan and 3-substituted-3-desoxymorphinan analogues as mixed κ and μ opioid ligands: synthesis and biological evaluation of their binding affinity at opioid receptors. J Med Chem 47: 165-174.
    • (2004) J Med Chem , vol.47 , pp. 165-174
    • Zhang, A.1    Xiong, W.2    Bidlack, J.M.3    Hilbert, J.E.4    Knapp, B.I.5    Wentland, M.P.6    Neumeyer, J.L.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.