Morphiceptin analogues containing a dipeptide mimetic structure: An investigation on the bioactive topology at the μ-receptor

Journal of Medicinal Chemistry

Volumn 48, Issue 9, 2005, Pages 3153-3163

  Grieco, Paolo ^a   Giusti, Laura ^b   Carotenuto, Alfonso ^a   Campiglia, Pietro ^a   Calderone, Vincenzo ^b   Lama, Teresa ^a   Gomez Monterrey, Isabel ^a   Tartaro, Gianpaolo ^c   Mazzoni, Maria R ^b   Novellino, Ettore ^a  

^a UNIVERSITY OF NAPLES FEDERICO II   (Italy)

^b UNIVERSITY OF PISA   (Italy)

^c SECOND UNIVERSITY OF NAPLES   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

7 BENZYLIDENENALTREXONE; AMIDE; AROMATIC COMPOUND; BACITRACIN; BENZYLSULFONYL FLUORIDE; BESTATIN; DIPEPTIDE; ENKEPHALIN[2 DEXTRO ALANINE 4 METHYLPHENYLALANINE 5 GLYCINE]; LEUPEPTIN; LOPERAMIDE; MORPHICEPTIN DERIVATIVE; MORPHINE; MU OPIATE RECEPTOR; NALOXONE; NALTRINDOLE; OPIATE PEPTIDE; PROLINE; TYROSINE;

AMINO TERMINAL SEQUENCE; ANIMAL TISSUE; ARTICLE; BINDING SITE; BIOLOGICAL ACTIVITY; CARBOXY TERMINAL SEQUENCE; CHEMICAL BOND; CIS TRANS ISOMERISM; CONTROLLED STUDY; DRUG RECEPTOR BINDING; GUINEA PIG; MALE; MOLECULAR MIMICRY; NONHUMAN; PHARMACOPHORE; PROTEIN CONFORMATION; PROTEIN STRUCTURE; RAT; RECEPTOR BINDING;

ANIMALS; BINDING SITES; BRAIN; COMPUTER SIMULATION; DIPEPTIDES; ENDORPHINS; GUINEA PIGS; ILEUM; MAGNETIC RESONANCE SPECTROSCOPY; MALE; MICELLES; MODELS, MOLECULAR; MOLECULAR CONFORMATION; MOLECULAR MIMICRY; MUSCLE CONTRACTION; MUSCLE, SMOOTH; RADIOLIGAND ASSAY; RATS; RECEPTORS, OPIOID, MU; SODIUM DODECYL SULFATE; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 20944433986     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm040867y     Document Type: Article

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