-
1
-
-
7744243019
-
Effects of acute and chronic lamotrigine treatment on basal and stimulated extracellular amino acids in the hippocampus of freely moving rats
-
Ahmad S., Fowler L.J., and Whitton P.S. Effects of acute and chronic lamotrigine treatment on basal and stimulated extracellular amino acids in the hippocampus of freely moving rats. Brain Res. 1029 (2004) 41-47
-
(2004)
Brain Res.
, vol.1029
, pp. 41-47
-
-
Ahmad, S.1
Fowler, L.J.2
Whitton, P.S.3
-
2
-
-
2542541297
-
Effect of acute and chronic lamotrigine on basal and stimulated extracellular 5-hydroxytryptamine and dopamine in the hippocampus of the freely moving rat
-
Ahmad S., Fowler L.J., and Whitton P.S. Effect of acute and chronic lamotrigine on basal and stimulated extracellular 5-hydroxytryptamine and dopamine in the hippocampus of the freely moving rat. Br. J. Pharmacol. 142 (2004) 136-142
-
(2004)
Br. J. Pharmacol.
, vol.142
, pp. 136-142
-
-
Ahmad, S.1
Fowler, L.J.2
Whitton, P.S.3
-
3
-
-
16844382736
-
The effects of acamprosate and neramexane on cue-induced reinstatement of ethanol-seeking behaviour in rat
-
Bachteler D., Economidou D., Danysz W., Ciccocioppo R., and Spanagel R. The effects of acamprosate and neramexane on cue-induced reinstatement of ethanol-seeking behaviour in rat. Neuropsychopharmacology 30 (2005) 1104-1110
-
(2005)
Neuropsychopharmacology
, vol.30
, pp. 1104-1110
-
-
Bachteler, D.1
Economidou, D.2
Danysz, W.3
Ciccocioppo, R.4
Spanagel, R.5
-
4
-
-
1942487239
-
Ionotropic glutamate receptor antagonists modulate cue-induced reinstatement of ethanol-seeking behaviour
-
Bäckström P., and Hyytiä P. Ionotropic glutamate receptor antagonists modulate cue-induced reinstatement of ethanol-seeking behaviour. Alcohol Clin. Exp. Res. 28 (2004) 558-565
-
(2004)
Alcohol Clin. Exp. Res.
, vol.28
, pp. 558-565
-
-
Bäckström, P.1
Hyytiä, P.2
-
6
-
-
0036710854
-
Effect of selective blockade of mu(1) or delta opioid receptors on reinstatement of alcohol-seeking behaviour by drug-associated stimuli in rats
-
Ciccocioppo R., Martin-Fardon R., and Weiss F. Effect of selective blockade of mu(1) or delta opioid receptors on reinstatement of alcohol-seeking behaviour by drug-associated stimuli in rats. Neuropsychopharmacology 27 (2002) 391-399
-
(2002)
Neuropsychopharmacology
, vol.27
, pp. 391-399
-
-
Ciccocioppo, R.1
Martin-Fardon, R.2
Weiss, F.3
-
7
-
-
28744441117
-
Can experimental paradigms and animal models be used to discover clinically effective medications for alcoholism?
-
Egli M. Can experimental paradigms and animal models be used to discover clinically effective medications for alcoholism?. Addict. Biol. 10 (2005) 309-319
-
(2005)
Addict. Biol.
, vol.10
, pp. 309-319
-
-
Egli, M.1
-
8
-
-
0032007883
-
Chronic acamprosate eliminates the alcohol deprivation effect while having limited effects on baseline responding for ethanol in rats
-
Heyser C.J., Schulteis G., Durbin P., and Koob G.F. Chronic acamprosate eliminates the alcohol deprivation effect while having limited effects on baseline responding for ethanol in rats. Neuropsychopharmacology 18 (1998) 125-133
-
(1998)
Neuropsychopharmacology
, vol.18
, pp. 125-133
-
-
Heyser, C.J.1
Schulteis, G.2
Durbin, P.3
Koob, G.F.4
-
9
-
-
0030608342
-
Evidence for alcohol anti-craving properties of memantine
-
Hölter S.M., Danysz W., and Spanagel R. Evidence for alcohol anti-craving properties of memantine. Eur. J. Pharmacol. 314 (1996) R1-R2
-
(1996)
Eur. J. Pharmacol.
, vol.314
-
-
Hölter, S.M.1
Danysz, W.2
Spanagel, R.3
-
10
-
-
0043234820
-
The non-competitive NMDA receptor antagonist MRZ 2/579 suppresses the alcohol deprivation effect in long-term alcohol drinking rats and substitutes the alcohol cue in a discrimination task
-
Hölter S.M., Danysz W., and Spanagel R. The non-competitive NMDA receptor antagonist MRZ 2/579 suppresses the alcohol deprivation effect in long-term alcohol drinking rats and substitutes the alcohol cue in a discrimination task. J. Pharmacol. Exp. Ther. 292 (2000) 545-552
-
(2000)
J. Pharmacol. Exp. Ther.
, vol.292
, pp. 545-552
-
-
Hölter, S.M.1
Danysz, W.2
Spanagel, R.3
-
11
-
-
0031910338
-
Long-term ethanol self-administration with repeated withdrawal episodes changes ethanol drinking pattern and increases anxiety during withdrawal in rats
-
Hölter S.M., Engelmann M., Kirschke C., Liebsch G., Landgraf R., and Spanagel R. Long-term ethanol self-administration with repeated withdrawal episodes changes ethanol drinking pattern and increases anxiety during withdrawal in rats. Behav. Pharmacol. 9 (1998) 41-48
-
(1998)
Behav. Pharmacol.
, vol.9
, pp. 41-48
-
-
Hölter, S.M.1
Engelmann, M.2
Kirschke, C.3
Liebsch, G.4
Landgraf, R.5
Spanagel, R.6
-
12
-
-
4544344682
-
An overview of the development of medications including novel anticonvulsants for the treatment of alcohol dependence
-
Johnson B.A. An overview of the development of medications including novel anticonvulsants for the treatment of alcohol dependence. Expert Opin. Pharmacother. 5 (2004) 1943-1955
-
(2004)
Expert Opin. Pharmacother.
, vol.5
, pp. 1943-1955
-
-
Johnson, B.A.1
-
13
-
-
33744471862
-
Serotonergic compounds: clinical data
-
Spanagel R., and Mann K. (Eds), Birkhäuser, Basel
-
Johnson B.A. Serotonergic compounds: clinical data. In: Spanagel R., and Mann K. (Eds). Drugs for Relapse Prevention of Alcoholism (2005), Birkhäuser, Basel 107-116
-
(2005)
Drugs for Relapse Prevention of Alcoholism
, pp. 107-116
-
-
Johnson, B.A.1
-
14
-
-
4444261097
-
Oral topiramate reduces the consequences of drinking and improves the quality of life of alcohol-dependent individuals: a randomized controlled trial
-
Johnson B.A., Ait-Daoud N., Akhtar F.Z., and Ma J.Z. Oral topiramate reduces the consequences of drinking and improves the quality of life of alcohol-dependent individuals: a randomized controlled trial. Arch. Gen. Psychiatry 61 (2004) 905-912
-
(2004)
Arch. Gen. Psychiatry
, vol.61
, pp. 905-912
-
-
Johnson, B.A.1
Ait-Daoud, N.2
Akhtar, F.Z.3
Ma, J.Z.4
-
15
-
-
14644405541
-
Unmanageable motivation in addiction: a pathology in prefrontal-accumbens glutamate transmission
-
Kalivas P.W., Volkow N., and Seamans J. Unmanageable motivation in addiction: a pathology in prefrontal-accumbens glutamate transmission. Neuron 45 (2005) 647-650
-
(2005)
Neuron
, vol.45
, pp. 647-650
-
-
Kalivas, P.W.1
Volkow, N.2
Seamans, J.3
-
16
-
-
18844363205
-
Use of lamotrigine to augment clozapine in patients with resistant schizophrenia and comorbid alcohol dependence: a potent anti-craving effect?
-
Kalyoncu A., Mirsal H., Pektas O., Unsalan N., Tan D., and Beyazyurek M. Use of lamotrigine to augment clozapine in patients with resistant schizophrenia and comorbid alcohol dependence: a potent anti-craving effect?. J. Psychopharmacol. 19 (2005) 301-305
-
(2005)
J. Psychopharmacol.
, vol.19
, pp. 301-305
-
-
Kalyoncu, A.1
Mirsal, H.2
Pektas, O.3
Unsalan, N.4
Tan, D.5
Beyazyurek, M.6
-
17
-
-
33947221100
-
Antiglutamatergic strategies for ethanol detoxification: comparison with placebo and diazepam
-
Krupitsky E.M., Rudenko A.A., Burakov A.M., Slavina T.Y., Grinenko A.A., Pittman B., Gueorguieva R., Petrakis I.L., Zvartau E.E., and Krystal J.H. Antiglutamatergic strategies for ethanol detoxification: comparison with placebo and diazepam. Alcohol Clin. Exp. Res. 31 (2007) 604-611
-
(2007)
Alcohol Clin. Exp. Res.
, vol.31
, pp. 604-611
-
-
Krupitsky, E.M.1
Rudenko, A.A.2
Burakov, A.M.3
Slavina, T.Y.4
Grinenko, A.A.5
Pittman, B.6
Gueorguieva, R.7
Petrakis, I.L.8
Zvartau, E.E.9
Krystal, J.H.10
-
18
-
-
0037526206
-
N-methyl-d-aspartate glutamate receptors and alcoholism: reward, dependence, treatment, and vulnerability
-
Krystal J.H., Petrakis I.L., Mason G., Trevisan L., and D`Souza D.C. N-methyl-d-aspartate glutamate receptors and alcoholism: reward, dependence, treatment, and vulnerability. Pharmacol. Ther. 99 (2003) 79-94
-
(2003)
Pharmacol. Ther.
, vol.99
, pp. 79-94
-
-
Krystal, J.H.1
Petrakis, I.L.2
Mason, G.3
Trevisan, L.4
D'Souza, D.C.5
-
19
-
-
36348977388
-
Serotonergic compounds: preclinical data
-
Spanagel R., and Mann K. (Eds), Birkhäuser, Basel
-
Lê A.D., and Funk R. Serotonergic compounds: preclinical data. In: Spanagel R., and Mann K. (Eds). Drugs for Relapse Prevention of Alcoholism (2005), Birkhäuser, Basel 95-106
-
(2005)
Drugs for Relapse Prevention of Alcoholism
, pp. 95-106
-
-
Lê, A.D.1
Funk, R.2
-
20
-
-
0032815730
-
Effects of naltrexone and fluoxetine on alcohol self-administration and reinstatement of alcohol-seeking induced by priming injections of alcohol and exposure to stress
-
Le A.D., Poulos C.X., Harding S., Watchus J., Juzytsch W., and Shaham Y. Effects of naltrexone and fluoxetine on alcohol self-administration and reinstatement of alcohol-seeking induced by priming injections of alcohol and exposure to stress. Neuropsychopharmacology 21 (1999) 435-444
-
(1999)
Neuropsychopharmacology
, vol.21
, pp. 435-444
-
-
Le, A.D.1
Poulos, C.X.2
Harding, S.3
Watchus, J.4
Juzytsch, W.5
Shaham, Y.6
-
21
-
-
0027310109
-
Studies on the mechanism of action of the novel anticonvulsant lamotrigine (Lamactil) using primary neurological cultures from rat cortex
-
Lees G., and Leach M.J. Studies on the mechanism of action of the novel anticonvulsant lamotrigine (Lamactil) using primary neurological cultures from rat cortex. Brain Res. 612 (1993) 190-199
-
(1993)
Brain Res.
, vol.612
, pp. 190-199
-
-
Lees, G.1
Leach, M.J.2
-
22
-
-
0036175909
-
Reversal of ethanol-seeking behavior by D1 and D2 antagonists in an animal model of relapse: differences in antagonist potency in previously ethanol-dependent versus nondependent rats
-
Liu X., and Weiss F. Reversal of ethanol-seeking behavior by D1 and D2 antagonists in an animal model of relapse: differences in antagonist potency in previously ethanol-dependent versus nondependent rats. J. Pharmacol. Exp. Ther. 300 (2002) 882-889
-
(2002)
J. Pharmacol. Exp. Ther.
, vol.300
, pp. 882-889
-
-
Liu, X.1
Weiss, F.2
-
24
-
-
0031937462
-
A preliminary investigation of lamotrigine for cocaine abuse in HIV-seropositive patients
-
Margolin A., Avants S.K., DePhilippis D., and Kosten T.R. A preliminary investigation of lamotrigine for cocaine abuse in HIV-seropositive patients. Am. J. Drug Alcohol Abuse 24 (1998) 85-101
-
(1998)
Am. J. Drug Alcohol Abuse
, vol.24
, pp. 85-101
-
-
Margolin, A.1
Avants, S.K.2
DePhilippis, D.3
Kosten, T.R.4
-
25
-
-
32144462790
-
A randomized, open-label, controlled trial of gabapentin and phenobarbital in the treatment of alcohol withdrawal
-
Mariani J.J., Rosenthal R.N., Tross S., Singh P., and Anand O.P. A randomized, open-label, controlled trial of gabapentin and phenobarbital in the treatment of alcohol withdrawal. Am. J. Addict. 15 (2006) 76-84
-
(2006)
Am. J. Addict.
, vol.15
, pp. 76-84
-
-
Mariani, J.J.1
Rosenthal, R.N.2
Tross, S.3
Singh, P.4
Anand, O.P.5
-
27
-
-
33846477292
-
A double-blind evaluation of gabapentin on alcohol effects and drinking in a clinical laboratory paradigm
-
Myrick H., Anton R., Voronin K., Wang W., and Henderson S. A double-blind evaluation of gabapentin on alcohol effects and drinking in a clinical laboratory paradigm. Alcohol Clin. Exp. Res. 31 (2007) 221-227
-
(2007)
Alcohol Clin. Exp. Res.
, vol.31
, pp. 221-227
-
-
Myrick, H.1
Anton, R.2
Voronin, K.3
Wang, W.4
Henderson, S.5
-
28
-
-
34247877587
-
Modulation of high alcohol drinking in the inbred fawn-hooded (FH/Wjd) rat strain: implications for treatment
-
Overstreet D.H., Rezvani A.H., Cowen M., Chen F., and Lawrence A.J. Modulation of high alcohol drinking in the inbred fawn-hooded (FH/Wjd) rat strain: implications for treatment. Addict. Biol. 11 (2006) 356-373
-
(2006)
Addict. Biol.
, vol.11
, pp. 356-373
-
-
Overstreet, D.H.1
Rezvani, A.H.2
Cowen, M.3
Chen, F.4
Lawrence, A.J.5
-
29
-
-
34248512527
-
New developments in the pharmacotherapy of cocaine abuse
-
Petri A. New developments in the pharmacotherapy of cocaine abuse. Addict. Biol. 12 (2007) 133-151
-
(2007)
Addict. Biol.
, vol.12
, pp. 133-151
-
-
Petri, A.1
-
30
-
-
0034190332
-
Effects of 5-HT(3) receptor antagonists on daily alcohol intake under acquisition, maintenance, and relapse conditions in alcohol-preferring (P) rats
-
Rodd-Henricks Z.A., McKinzie D.L., Edmundson V.E., Dagon C.L., Murphy J.M., McBride W.J., Lumeng L., and Li T.K. Effects of 5-HT(3) receptor antagonists on daily alcohol intake under acquisition, maintenance, and relapse conditions in alcohol-preferring (P) rats. Alcohol 21 (2000) 73-85
-
(2000)
Alcohol
, vol.21
, pp. 73-85
-
-
Rodd-Henricks, Z.A.1
McKinzie, D.L.2
Edmundson, V.E.3
Dagon, C.L.4
Murphy, J.M.5
McBride, W.J.6
Lumeng, L.7
Li, T.K.8
-
31
-
-
33646587064
-
Effects of lamotrigine in patients with bipolar disorder and alcohol dependence
-
Rubio G., Lopez-Munoz F., and Alamo C. Effects of lamotrigine in patients with bipolar disorder and alcohol dependence. Bipolar Disord 8 (2006) 289-293
-
(2006)
Bipolar Disord
, vol.8
, pp. 289-293
-
-
Rubio, G.1
Lopez-Munoz, F.2
Alamo, C.3
-
32
-
-
1242337444
-
Effects of topiramate in the treatment of alcohol dependence
-
Rubio G., Ponce G., Jimenez-Arriero M.A., Palomo T., Manzanares J., and Ferre F. Effects of topiramate in the treatment of alcohol dependence. Pharmacopsychiatry 37 (2004) 37-40
-
(2004)
Pharmacopsychiatry
, vol.37
, pp. 37-40
-
-
Rubio, G.1
Ponce, G.2
Jimenez-Arriero, M.A.3
Palomo, T.4
Manzanares, J.5
Ferre, F.6
-
33
-
-
0022497706
-
Initiation of ethanol reinforcement using a sucrose-substitution procedure in food- and water-sated rats
-
Samson H.H. Initiation of ethanol reinforcement using a sucrose-substitution procedure in food- and water-sated rats. Alcohol Clin. Exp. Res. 10 (1986) 436-442
-
(1986)
Alcohol Clin. Exp. Res.
, vol.10
, pp. 436-442
-
-
Samson, H.H.1
-
34
-
-
33750686609
-
Behavioural assessment of drug-reinforcement and addictive features in rodents: an overview
-
Sanchis-Segura C., and Spanagel R. Behavioural assessment of drug-reinforcement and addictive features in rodents: an overview. Addict. Biol. 11 (2006) 2-38
-
(2006)
Addict. Biol.
, vol.11
, pp. 2-38
-
-
Sanchis-Segura, C.1
Spanagel, R.2
-
35
-
-
0038786581
-
The reinstatement model of drug relapse: history, methodology and major findings
-
Shaham Y., Shalev U., Lu L., De Wit H., and Stewart J. The reinstatement model of drug relapse: history, methodology and major findings. Psychopharmacology (Berl.) 168 (2003) 3-20
-
(2003)
Psychopharmacology (Berl.)
, vol.168
, pp. 3-20
-
-
Shaham, Y.1
Shalev, U.2
Lu, L.3
De Wit, H.4
Stewart, J.5
-
36
-
-
13444254068
-
The circadian clock gene Period2 alters the glutamatergic system and thereby modulates alcohol consumption
-
Spanagel R., Pendyala G., Abarca C., Zghoul T., Sanchis-Segura, Magnone M.C., Lascorz J., Depner M., Holzberg D., Soyka M., Schreiber S., Matsuda F., Lathrop M., Schumann G., and Albrecht U. The circadian clock gene Period2 alters the glutamatergic system and thereby modulates alcohol consumption. Nat. Med. 11 (2005) 35-42
-
(2005)
Nat. Med.
, vol.11
, pp. 35-42
-
-
Spanagel, R.1
Pendyala, G.2
Abarca, C.3
Zghoul, T.4
Sanchis-Segura5
Magnone, M.C.6
Lascorz, J.7
Depner, M.8
Holzberg, D.9
Soyka, M.10
Schreiber, S.11
Matsuda, F.12
Lathrop, M.13
Schumann, G.14
Albrecht, U.15
-
37
-
-
0033231660
-
The dopamine hypothesis of reward: past and current status
-
Spanagel R., and Weiss F. The dopamine hypothesis of reward: past and current status. Trends Neurosci. 22 (1999) 521-527
-
(1999)
Trends Neurosci.
, vol.22
, pp. 521-527
-
-
Spanagel, R.1
Weiss, F.2
-
38
-
-
0031081578
-
Anti-craving compounds for ethanol: new pharmacological tools to study addictive processes
-
Spanagel R., and Zieglgansberger W. Anti-craving compounds for ethanol: new pharmacological tools to study addictive processes. Trends Pharmacol. Sci. 18 (1997) 54-59
-
(1997)
Trends Pharmacol. Sci.
, vol.18
, pp. 54-59
-
-
Spanagel, R.1
Zieglgansberger, W.2
-
39
-
-
0031959272
-
The role of glutamatergic neurotransmission in the pathophysiology of alcoholism
-
Tsai G., and Coyle J.T. The role of glutamatergic neurotransmission in the pathophysiology of alcoholism. Annu. Rev. Med. 49 (1998) 173-184
-
(1998)
Annu. Rev. Med.
, vol.49
, pp. 173-184
-
-
Tsai, G.1
Coyle, J.T.2
-
40
-
-
16844386330
-
The role of the NMDA receptor in alcohol relapse: a pharmacological mapping study using the alcohol deprivation effect
-
Vengeliene V., Bachteler D., Danysz W., and Spanagel R. The role of the NMDA receptor in alcohol relapse: a pharmacological mapping study using the alcohol deprivation effect. Neuropharmacology 48 (2005) 822-829
-
(2005)
Neuropharmacology
, vol.48
, pp. 822-829
-
-
Vengeliene, V.1
Bachteler, D.2
Danysz, W.3
Spanagel, R.4
-
41
-
-
33845655197
-
The D3 receptor plays an essential role in alcohol craving and relapse
-
Vengeliene V., Leonardi-Essmann F., Perreau-Lenz S., Gebicke-Haerter P., Drescher K., Gross G., and Spanagel R. The D3 receptor plays an essential role in alcohol craving and relapse. FASEB J. 20 (2006) 2223-2233
-
(2006)
FASEB J.
, vol.20
, pp. 2223-2233
-
-
Vengeliene, V.1
Leonardi-Essmann, F.2
Perreau-Lenz, S.3
Gebicke-Haerter, P.4
Drescher, K.5
Gross, G.6
Spanagel, R.7
-
42
-
-
0035919746
-
Lamotrigine inhibition of glutamate release from isolated cerebrocortical nerve terminals (synaptosomes) by suppression of voltage-activated calcium channel activity
-
Wang S.J., Sibra T.S., and Gean P.W. Lamotrigine inhibition of glutamate release from isolated cerebrocortical nerve terminals (synaptosomes) by suppression of voltage-activated calcium channel activity. Neuroreport 12 (2001) 2255-2258
-
(2001)
Neuroreport
, vol.12
, pp. 2255-2258
-
-
Wang, S.J.1
Sibra, T.S.2
Gean, P.W.3
-
43
-
-
33845655693
-
Dopaminergic compounds: preclinical data
-
Spanagel R., and Mann K. (Eds), Birkhäuser, Basel
-
Weiss F. Dopaminergic compounds: preclinical data. In: Spanagel R., and Mann K. (Eds). Drugs for Relapse Prevention of Alcoholism (2005), Birkhäuser, Basel 135-153
-
(2005)
Drugs for Relapse Prevention of Alcoholism
, pp. 135-153
-
-
Weiss, F.1
-
44
-
-
12344279071
-
Neurobiology of craving, conditioned reward and relapse
-
Weiss F. Neurobiology of craving, conditioned reward and relapse. Curr. Opin. Pharmacol. 5 (2005) 9-19
-
(2005)
Curr. Opin. Pharmacol.
, vol.5
, pp. 9-19
-
-
Weiss, F.1
-
45
-
-
33846210165
-
Dopaminergic compounds: clinical data
-
Spanagel R., and Mann K. (Eds), Birkhäuser, Basel
-
Wiesbeck G.A. Dopaminergic compounds: clinical data. In: Spanagel R., and Mann K. (Eds). Drugs for Relapse Prevention of Alcoholism (2005), Birkhäuser, Basel 155-161
-
(2005)
Drugs for Relapse Prevention of Alcoholism
, pp. 155-161
-
-
Wiesbeck, G.A.1
|