Crocetin suppresses angiotensin II-induced vascular smooth-muscle cell proliferation through inhibition of ERK1/2 activation and cell-cycle progression

Journal of Cardiovascular Pharmacology

Volumn 50, Issue 5, 2007, Pages 519-525

  Zheng, Shuguo ^a   Qian, Zhiyu ^b   Wen, Na ^b   Xi, Liang ^b  

^a WANNAN MEDICAL COLLEGE   (China)

^b CHINA PHARMACEUTICAL UNIVERSITY   (China)

Author keywords

Angiotensin; Cell cycle; Crocetin; Extracellular signal regulated kinase1 2 (ERK1 2); Proliferation; Vascular smooth muscle cells

Indexed keywords

ANGIOTENSIN II; CROCETIN; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; REACTIVE OXYGEN METABOLITE; SUPEROXIDE DISMUTASE; THYMIDINE; TRITIUM;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ANTIOXIDANT ACTIVITY; AORTA; ARTICLE; CELL ACTIVITY; CELL CYCLE G0 PHASE; CELL CYCLE G1 PHASE; CELL CYCLE PROGRESSION; CELL PROLIFERATION; CONTROLLED STUDY; COW; ENZYME ACTIVATION; ENZYME ACTIVITY; FLOW CYTOMETRY; GENE EXPRESSION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; NONHUMAN; ONCOGENE C FOS; PRIORITY JOURNAL; VASCULAR SMOOTH MUSCLE;

ANGIOTENSIN II; ANIMALS; ANTIOXIDANTS; CAROTENOIDS; CATTLE; CELL CYCLE; CELL PROLIFERATION; CELLS, CULTURED; DOSE-RESPONSE RELATIONSHIP, DRUG; ENZYME ACTIVATION; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; GENE EXPRESSION; MITOGEN-ACTIVATED PROTEIN KINASE 1; MITOGEN-ACTIVATED PROTEIN KINASE 3; MITOGEN-ACTIVATED PROTEIN KINASES; MOLECULAR STRUCTURE; MYOCYTES, SMOOTH MUSCLE; NADPH OXIDASE; PHOSPHORYLATION; PROTO-ONCOGENE PROTEINS C-FOS; REACTIVE OXYGEN SPECIES; RNA, MESSENGER; SUPEROXIDE DISMUTASE;

EID: 36348960666     PISSN: 01602446     EISSN: None     Source Type: Journal    
DOI: 10.1097/FJC.0b013e31813c114e     Document Type: Article

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