Inhibitory effects of tetrandrine on the serum- and platelet-derived growth factor-BB-induced proliferation of rat aortic smooth muscle cells through inhibition of cell cycle progression, DNA synthesis, ERK1/2 activation and c-fos expression

Atherosclerosis

Volumn 174, Issue 2, 2004, Pages 215-223

  Fang, Lian Hua ^a   Zhang, Yong He ^b   Ma, Jing Jie ^c   Du, Guan Hua ^a   Ku, Bao Shan ^b   Yao, Hai Yan ^b   Yun, Yeo Pyo ^d   Kim, Tack Joong ^d  

^a INSTITUTE OF MATERIA MEDICA   (China)

^b PEKING UNIVERSITY HEALTH SCIENCE CENTER   (China)

^c YANBIAN UNIVERSITY   (China)

^d Chungbuk National University   (South Korea)

Author keywords

c fos; Cell cycle; MAPK; Proliferation; Tetrandrine

Indexed keywords

CALCIUM ANTAGONIST; CALCIUM ION; DNA; MITOGEN ACTIVATED PROTEIN KINASE 1; PLATELET DERIVED GROWTH FACTOR BB; PROTEIN C FOS; TETRANDRINE; THYMIDINE; VERAPAMIL;

ANIMAL CELL; AORTA MEDIA; ARTICLE; CALCIUM ANTAGONISM; CELL CYCLE; CELL PROLIFERATION; CELL SYNCHRONIZATION; CONCENTRATION RESPONSE; CONTROLLED STUDY; DNA SYNTHESIS; DRUG EFFECT; DRUG INHIBITION; DRUG MECHANISM; DRUG POTENCY; ENZYME ACTIVATION; ENZYME PHOSPHORYLATION; FLOW CYTOMETRY; MITOGENESIS; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; SMOOTH MUSCLE FIBER;

ALKALOIDS; ANALYSIS OF VARIANCE; ANIMALS; AORTA; BENZYLISOQUINOLINES; BLOTTING, WESTERN; CELL CYCLE; CELL DIVISION; CELLS, CULTURED; DNA; ENZYME ACTIVATION; MALE; MITOGEN-ACTIVATED PROTEIN KINASE 3; MITOGEN-ACTIVATED PROTEIN KINASES; MUSCLE, SMOOTH, VASCULAR; MYOCYTES, SMOOTH MUSCLE; PLATELET-DERIVED GROWTH FACTOR; POLYMERASE CHAIN REACTION; PROBABILITY; PROTO-ONCOGENE PROTEINS C-FOS; RATS; RATS, SPRAGUE-DAWLEY; SENSITIVITY AND SPECIFICITY;

EID: 2342584670     PISSN: 00219150     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.atherosclerosis.2004.01.036     Document Type: Article

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