Expression of the heparan sulfate-degrading enzyme heparanase is induced in infiltrating CD4+ T cells in experimental autoimmune encephalomyelitis and regulated at the level of transcription by early growth response gene 1

Journal of Leukocyte Biology

Volumn 82, Issue 5, 2007, Pages 1289-1300

  De Mestre, Amanda M ^a,b   Staykova, Maria A ^c   Hornby, June R ^a   Willenborg, David O ^c   Hulett, Mark D ^a  

^a Australian National University   (Australia)

^b Department of Obstetrics Gynecology   (United States)

^c CANBERRA HOSPITAL   (Australia)

Author keywords

Autoimmunity; Extracellular matrix; Inflammation; Migration; Multiple sclerosis

Indexed keywords

EARLY GROWTH RESPONSE FACTOR 1; HEPARANASE; MESSENGER RNA; SMALL INTERFERING RNA;

ALLERGIC ENCEPHALOMYELITIS; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CD4+ T LYMPHOCYTE; CD8+ T LYMPHOCYTE; CELL INFILTRATION; CENTRAL NERVOUS SYSTEM; CONTROLLED STUDY; DISEASE COURSE; ENZYME ACTIVITY; GENE CONTROL; HUMAN; INFLAMMATORY DISEASE; NONHUMAN; PRIORITY JOURNAL; RAT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; TRANSCRIPTION REGULATION;

ANIMALS; ASTROCYTES; BLOTTING, WESTERN; CD4-POSITIVE T-LYMPHOCYTES; CENTRAL NERVOUS SYSTEM; DISEASE PROGRESSION; EARLY GROWTH RESPONSE PROTEIN 1; ENCEPHALOMYELITIS, AUTOIMMUNE, EXPERIMENTAL; GENE EXPRESSION REGULATION; GLUCURONIDASE; HEPARITIN SULFATE; HUMANS; IMMUNIZATION; LEUKOCYTES, MONONUCLEAR; LUCIFERASES; LYMPHOCYTE ACTIVATION; MACROPHAGES; PLASMIDS; PROMOTER REGIONS (GENETICS); RATS; RATS, INBRED LEW; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; SPLEEN; TRANSCRIPTION, GENETIC;

RATTUS;

EID: 36249028186     PISSN: 07415400     EISSN: None     Source Type: Journal    
DOI: 10.1189/jlb.0507315     Document Type: Article

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