A synthetic heparin-mimicking polyanionic compound inhibits central nervous system inflammation

Journal of the Neurological Sciences

Volumn 206, Issue 1, 2003, Pages 49-57

  Irony Tur Sinai, Michal ^a   Vlodavsky, Israel ^a   Ben Sasson, Shmuel A ^a   Pinto, Florence ^a   Sicsic, Camille ^a   Brenner, Talma ^a  

^a HADASSAH HEBREW UNIVERSITY MEDICAL CENTER   (Israel)

Author keywords

CNS inflammation; EAE; Heparanase; Heparin mimicking polyanionic compound (HMPAC); Immunomodulation; Multiple sclerosis

Indexed keywords

ACETIC ACID DERIVATIVE; ENOXAPARIN; HEPARANASE; LOW MOLECULAR WEIGHT HEPARIN; MITOGEN ACTIVATED PROTEIN KINASE 1; POLY 4 HYDROXYPHENOXYACETIC ACID; PROSTAGLANDIN E2; RG 13577; UNCLASSIFIED DRUG;

ALLERGIC ENCEPHALOMYELITIS; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; ASTROCYTE; CELL PROLIFERATION; CENTRAL NERVOUS SYSTEM INFECTION; CONTROLLED STUDY; DISEASE SEVERITY; ENZYME ACTIVITY; FEMALE; IN VITRO STUDY; IN VIVO STUDY; LYMPHOCYTE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION; SPINAL CORD;

ANIMALS; ANTICOAGULANTS; BRAIN; CENTRAL NERVOUS SYSTEM; DINOPROSTONE; DNA PRIMERS; ENCEPHALOMYELITIS, AUTOIMMUNE, EXPERIMENTAL; FEMALE; GLUCURONIDASE; HEPARIN; INFLAMMATION; MICE; MICE, INBRED STRAINS; PHENOXYACETATES; PHOSPHORYLATION; PHOSPHOTYROSINE; POLYMERS; SPINAL CORD;

EID: 0037437666     PISSN: 0022510X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0022-510X(02)00318-0     Document Type: Article

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