Translocator protein (18 kDa) ligand PK 11195 induces transient mitochondrial Ca2+ release leading to transepithelial Cl- secretion in HT-29 human colon cancer cells

Biology of the Cell

Volumn 99, Issue 11, 2007, Pages 639-647

  Ostuni, Mariano A ^a   Ducroc, Robert ^a   Péranzi, Gabriel ^a   Tonon, Marie Christine ^b   Papadopoulos, Vassilios ^c   Lacapere, Jean Jacques ^a  

^a CENTRE DE RECHERCHE BIOMÉDICALE BICHAT BEAUJON CRB3   (France)

^b INSERM   (France)

^c GEORGETOWN UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

Calcium; Endozepine; Mitochondria; Peripheral benzodiazepine receptor; Translocator protein (TSPO)

Indexed keywords

5 NITRO 2 (3 PHENYLPROPYLAMINO)BENZOIC ACID; BUMETANIDE; CALCIUM ION; CHLORIDE ION; CYCLOSPORIN A; ETHYLENE GLYCOL 1,2 BIS(2 AMINOPHENYL) ETHER N,N,N',N' TETRAACETIC ACID; FLUNITRAZEPAM; LIGAND; MEMBRANE PROTEIN; N SEC BUTYL 1 (2 CHLOROPHENYL) N METHYL 3 ISOQUINOLINECARBOXAMIDE; SODIUM POTASSIUM CHLORIDE COTRANSPORTER; TRANSLOCATOR PROTEIN; TRITIUM; UNCLASSIFIED DRUG;

ARTICLE; BINDING AFFINITY; CALCIUM CELL LEVEL; CALCIUM TRANSPORT; CANCER CELL CULTURE; CELL MEMBRANE PERMEABILITY; CELL STIMULATION; COLON CANCER; CONTROLLED STUDY; CYTOSOL; EPITHELIUM; EXTRACELLULAR CALCIUM; HUMAN; HUMAN CELL; IMMUNOHISTOCHEMISTRY; LIGAND BINDING; MITOCHONDRIAL MEMBRANE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN LOCALIZATION;

ANGIOGENESIS INHIBITORS; ANTINEOPLASTIC AGENTS; CALCIUM; CELL LINE, TUMOR; CHLORIDES; COLONIC NEOPLASMS; CYCLOSPORINE; ENZYME INHIBITORS; FLUNITRAZEPAM; GABA MODULATORS; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; ISOQUINOLINES; LIGANDS; MITOCHONDRIA; MITOCHONDRIAL MEMBRANES; MITOCHONDRIAL PROTEINS; NEOPLASM PROTEINS; NITROBENZOATES; RECEPTORS, GABA; SODIUM-POTASSIUM-CHLORIDE SYMPORTERS;

TETRA;

EID: 36249010236     PISSN: 02484900     EISSN: None     Source Type: Journal    
DOI: 10.1042/BC20070048     Document Type: Article

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