A brief history of CD8 T cells

European Journal of Immunology

Volumn 37, Issue SUPPL. 1, 2007, Pages

  Masopust, David ^a   Vezys, Vaiva ^a   Wherry, E John ^b   Ahmed, Rafi ^c  

^a UNIVERSITY OF MINNESOTA   (United States)

^b WISTAR INSTITUTE   (United States)

^c EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

CD8 T cells; Cellular immunology; History; Memory; MHC

Indexed keywords

EPITOPE; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 1; T LYMPHOCYTE RECEPTOR;

ADAPTIVE IMMUNITY; ARTICLE; AUTOIMMUNITY; BINDING AFFINITY; CD4+ T LYMPHOCYTE; CD8+ T LYMPHOCYTE; CELL DIFFERENTIATION; CELL PROLIFERATION; CELLULAR IMMUNITY; HUMAN; IMMUNE RESPONSE; IMMUNOBIOLOGY; LYMPHOCYTE FUNCTION; MAJOR HISTOCOMPATIBILITY COMPLEX; MEMORY CELL; NONHUMAN; PRIORITY JOURNAL; PROTEIN STRUCTURE; T LYMPHOCYTE ACTIVATION;

ALLERGY AND IMMUNOLOGY; ANIMALS; CD8-POSITIVE T-LYMPHOCYTES; HISTORY, 20TH CENTURY; HISTORY, 21ST CENTURY; HUMANS;

EID: 36248989681     PISSN: 00142980     EISSN: None     Source Type: Journal    
DOI: 10.1002/eji.200737584     Document Type: Article

References (76)

1. Silverstein, A. M., The lymphocyte in immunology: from James B. Murphy to James L. Gowans. Nat. Immunol. 2001. 2: 569-571.
2. Murphy, J. B., Studies in tissue specificity: II. The ultimate fate of mammalian tissue implanted in chick embryo. J. Exp. Med. 1914. 19: 181-186.
3. Murphy, J. B., Factors of resistance to heteroplastic tissue-grafting:studies in tisses specificity III. J. Exp. Med. 1914. 19: 513-522.
4. Rich, A. R., The Pathogenesis of Tuberculosis. Charles C. Thomas, Springfield, IL 1951
5. Gowans, J. L., The lymphocyte-a disgraceful gap in medical knowledge. Immunol. Today 1996. 17: 288-291.
6. Gowans, J. L. and Knight, E. J., The route of re-circulation of lymphocytes in the rat. Proc. R. Soc. Lond. B Biol. Sci. 1964. 159: 257-282.
7. Gowans, J. L. and Uhr, J. W., The carriage of immunological memory by small lymphocytes in the rat. J. Exp. Med. 1966. 124: 1017-1030.
8. Howard, J. C. and Gowans, J. L., The role of lymphocytes in antibody formation. 3. The origin frorn small lymphocytes of cells forming direct and indirect haemolytic plaques to sheep erythrocytes in the rat. Proc. P, Soc. Lond. B Biol. Sci. 1972. 1. 82: 193-209.
9. Ellis, S. T. and Gowans, J. L., The role of lymphocytes in antibody formation. V. Transfer of immunological memory to tetanus toxoid: the origin of plasma cells from small lymphocytes, stimulation of memory cells in vitro and the persistence of memory after cell-transfer. Proc. R. Soc. Land. B Biol. Sci. 1973. 183: 125-139.
10. Miller, J. F., Immunological function of the thymus. Lancet 1961. 2: 748-749.
11. Miller, J. F. and Mitchell, G. F., The thymus and the precursors of antigen reactive cells. Nature 1967. 216: 659-663.
12. Mitchell, G. F. and Miller, J. F., Immunological activity of thymus and thoracic-duct lymphocytes. Proc. Natl. Acad. Sci. USA 1968. 59: 296-303.
13. Miller, J. F., Discovering the origins of immunological competence. Annu. Rev. Immunol. 1999. 17: 1-17.
14. Mosmann, T. R., Cherwinski, H., Bond, M. W., Giedlin, M. A. and Coffman, R. L., Two types of murine helper T cell clone. I. Definition according to profiles of lymphokine activities and secreted proteins. J. Immunol. 1986. 136: 2348-2357.
15. Sallusto, F., Lenig, D., Forster, R., Lipp, M. and Lanzavecchia, A., Two subsets of memory T lymphocytes with distinct homing potentials and effector functions. Nature 1999. 401: 708-712.
16. Govaerts, A., Cellular antibodies in kidney homotransplantation. J. Immunol. 1960. 85: 516-522.
17. Cerottini, J. C., Nordin, A. A. and Brunner, K. T., Specific in vitro cytotoxicity of thymus-derived lymphocytes sensitized to alloantigens. Nature 1970. 228: 1308-1309.
18. Golstein, P., Wigzell, H., Blomgren, H. and Svedmyr, E. A., Cells mediating specific in vitro cytotoxicity. II. Probable autonomy of thymus-processed lymphocytes (T cells) for the killing of allogeneic target cells. J. Exp. Med. 1972. 135: 890-906.
19. Brondz, B. D., Complex specificity of immune lymphocytes in allogeneic cell cultures. Folia Biol. (Praha) 1968. 14: 115-131.
20. Brondz, B. D. and Golberg, N. E., Further in vitro evidence for polyvalent specificity of immune lymphocytes. Folia Biol. (Praha) 1970. 16: 20-28.
21. Golstein, P., Erik, M. D., Svedmyr, A. J. and Wigzell, H., Cells mediating specific in vitro cytotoxicity. I. Detection of receptor-bearing lymphocytes. J. Exp. Med. 1971. 134: 1385-1402.
22. Cantor, H. and Boyse, E. A., Functional subclasses of T-lymphocytes bearing different Ly antigens. I. The generation of functionally distinct T-cell subclasses is a differentiative process independent of antigen. J. Exp. Med. 1975. 141: 1376-1389.
23. Shiku, H., Kisielow, P., Bean, M. A., Takahashi, T., Boyse, E. A., Oettgen, H. F. and Old, L. J., Expression of T-cell differentiation antigens on effector cells in cell-mediated cytotoxicity in vitro. Evidence for functional heterogeneity related to the surface phenotype of T cells. J. Exp. Med. 1975. 141: 227-241.
24. Kisielow, P., Hirst, J. A., Shiku, H., Beverley, P. C., Hoffman, M. K., Boyse, E. A. and Oettgen, H. F., Ly antigens as markers for functionally distinct subpopulations of thymus-derived lymphocytes of the mouse. Nature 1975. 253: 219-220.
25. Zinkernagel, R. M. and Doherty, P. C., Restriction of in vitro T cell-mediated cytotoxicity in lymphocytic choriomeningitis within a syngeneic or semiallogeneic system. Nature 1974. 248: 701-702.
26. Zinkernagel, R. M. and Doherty, P. C., Immunological surveillance against altered self components by sensitised T lymphocytes in lymphocytic choriomeningitis. Nature 1974. 251: 547-548.
27. Allison, J. P., McIntyre, B. W. and Bloch, D., Tumor-specific antigen of murine T-lymphoma defined with monoclonal antibody. J. Immunol. 1982. 129: 2293-2300.
28. Meuer, S. C., Fitzgerald, K. A., Hussey, R. E., Hodgdon, J. C., Schlossman, S. F. and Reinherz, E. L., Clonotypic structures involved in antigen-specific human T cell function. Relationship to the T3 molecular complex. J. Exp. Med. 1983. 157: 705-719.
29. Haskins, K., Kubo, R., White, J., Pigeon, M., Kappler, J. and Marrack, P., The major histocompatibility complex-restricted antigen receptor on T cells. I. Isolation with a monoclonal antibody. J. Exp. Med. 1983. 157: 1149-1169.
30. Samelson, L. E., Germain, R. N. and Schwartz, R. H., Monoclonal antibodies against the antigen receptor on a cloned T-cell hybrid. Proc. Natl. Acad. Sci. USA 1983. 80: 6972-6976.
31. Bigler, R. D., Fisher, D. E., Wang, C. Y., Rinnooy Kan, E. A. and Kunkel, H. G., Idiotype-like molecules on cells of a human T cell leukemia. J. Exp. Med. 1983. 158: 1000-1005.
32. Bevan, M. J., The major histocompatibility complex determines susceptibility to cytotoxic T cells directed against minor histocompatibility antigens. J. Exp. Med. 1975. 142: 1349-1364.
33. Gordon, R. D., Simpson, E. and Samelson, L. E., In vitro cell-mediated immune responses to the male specific(H-Y) antigen in mice. J. Exp. Med. 1975. 142: 1108-1120.
34. Hunig, T. R. and Bevan, M. J., Antigen recognition by cloned cytotoxic T lymphocytes follows rules predicted by the altered-self hypothesis. J. Exp. med. 1982. 155: 111-125.
35. Shimonkevitz, R., Kappler, J., Marrack, P. and Grey, H., Antigen recognition by H-2-restricted T cells. I. Cell-free antigen processing. J. Exp. Med. 1983. 158: 303-316.
36. Townsend, A. R., Gotch, F. M. and Davey, J., Cytotoxic T cells recognize fragments of the influenza nucleoprotein. Cell 1985. 42: 457-467.
37. Yewdell, J. W., Bennink, J. R., Smith, G. L. and Moss, B., Influenza A virus nucleoprotein is a major target antigen for cross-reactive anti-influenza A virus cytotoxic T lymphocytes. Proc. Natl. Acad. Sci. USA 1985. 82: 1785-1789.
38. Townsend, A. R. and Skehel, J. J., Influenza A specific cytotoxic T-cell clones that do not recognize viral glycoproteins. Nature 1982. 300: 655-657.
39. Townsend, A. R., Rothbard, J., Gotch, F. M., Bahadur, G., Wraith, D. and McMichael, A. J., The epitopes of influenza nucleoprotein recognized by cytotoxic T lymphocytes can be defined with short synthetic peptides. Cell 1986. 44: 959-968.
40. Kappler, J., Kubo, R., Haskins, K., Hannum, C., Marrack, P., Pigeon, M., McIntyre, B. et al., The major histocompatibility complex-restricted antigen receptor on T cells in mouse and man: identification of constant and variable peptides. Cell 1983. 35: 295-302.
41. Kappler, J., Kubo, R., Haskins, K., White, J. and Marrack, P., The mouse T cell receptor: comparison of MHC-restricted receptors on two T cell hybridomas. Cell 1983. 34: 727-737.
42. McIntyre, B. W. and Allison, J. P., The mouse T cell receptor: structural heterogeneity of molecules of normal T cells defined by xenoantiserum. Cell 1983. 34: 739-746.
43. Hedrick, S. M., Cohen, D. I., Nielsen, E. A. and Davis, M. M., Isolation of cDNA clones encoding T cell-specific membrane-associated proteins. Nature 1984. 308: 149-153.
44. Hedrick, S. M., Nielsen, E. A., Kavaler, J., Cohen, D. I. and Davis, M. M., Sequence relationships between putative T-cell receptor polypeptides and immunoglobulins. Nature 1984. 308: 153-158.
45. Yanagi, Y., Yoshikai, Y., Leggett, K., Clark, S. P., Aleksander, I. and Mak, T. W., A human Tcell-specific cDNA clone encodes a protein having extensive homology to immunoglobulin chains. Nature 1984. 308: 145-149.
46. Bjorkman, P. J., Saper, M. A., Samraoui, B., Bennett, W. S., Strominger, J. L. and Wiley, D. C., Structure of the human class I histocompatibility antigen, HLA-A2. Nature 1987. 329: 506-512.
47. Bjorkman, P. J., Saper, M. A., Samraoui, B., Bennett, W. S., Strominger, J. L. and Wiley, D. C., The foreign antigen binding site and T cell recognition regions of class I histocompatibility antigens. Nature 1987. 329: 512-518.
48. Parham, P., Putting a face to MHC restriction. J. Immunol. 2005. 174: 3-5.
49. Blue, M. L., Craig, K. A., Anderson, P., Branton, K. R., Jr. and Schlossman, S. F., Evidence for specific association between class I major histocompatibility antigens and the CD8 molecules of human suppressor/cytotoxic cells. Cell 1988. 54: 413-421.
50. Norment, A. M., Salter, R. D., Parham, P., Engethard, V. H. and Littman, D. R., Cell-cell adhesion mediated by CD8 and MHC class I molecules. Nature 1988. 336: 79-81.
51. Rosenstein, Y., Ratnofsky, S., Burakoff, S. J. and Herrmann, S. H., Direct evidence for binding of CD8 to HLA class I antigens. J. Exp. Med. 1989. 169: 149-160.
52. Salter, R. D., Norment, A. M., Chen, B. P., Clayberger, C., Krensky, A. M., Littman, D. R. and Parham, P., Polymorphism in the alpha 3 domain of HLA-A molecules affects binding to CD8. Nature 1989. 338: 345-347.
53. Garboczi, D. N., Ghosh, P., Utz, U., Fan, Q. R., Biddison, W. E. and Wiley, D. C., Structure of the complex between human T-cell receptor, viral peptide and HLA-A2. Nature 1996. 384: 134-141.
54. Rotzschke, O., Falk, K., Deres, K., Schild, H., Norda, M., Metzger, J., Jung, G. and Rammensee, H. G., Isolation and analysis of naturally processed viral peptides as recognized by cytotoxic T cells. Nature 1990. 348: 252-254.
55. Falk, K., Rotzschke, O., Deres, K., Metzger, J., Jung, G. and Rammensee, H. G., Identification of naturally processed viral nonapeptides allows their quantification in infected cells and suggests an allele-specific T cell epitope forecast. J. Exp. Med. 1991. 174: 425-434.
56. Falk, K., Rotzschke, O., Stevanovic, S., Jung, G. and Rammensee, H. G., Allele-specific motifs revealed by sequencing of self-peptides eluted from MHC molecules. Nature 1991. 351: 290-296.
57. Lau, L. L., Jamieson, B. D., Somasundaram, T. and Ahmed, R., Cytotoxic T-cell memory without antigen. Nature 1994. 369: 648-652.
58. Murali-Krishna, K., Lau, L. L., Sambhara, S., Lemonnier, F., Altman, J. and Ahmed, R., Persistence of memory CD8 T cells in MHC class I-deficient mice. Science 1999. 286: 1377-1381.
59. Swain, S. L., Hu, H. and Huston, G., Class II-independent generation of CD4 memory T cells from effectors. Science 1999. 286: 1381-1383.
60. Surh, C. D., Boyman, O., Purton, J. F. and Sprent, J., Homeostasis of memory T cells. Immunol. Rev. 2006. 211: 154-163.
61. Murali-Krishna, K., Altman, J. D., Suresh, M., Sourdive, D. J., Zajac, A. J., Miller, J. D., Slansky, J. and Ahmed, R., Counting antigen-specific CD8 T cells: a reevaluation of bystander activation during viral infection. Immunity 1998. 8: 177-187
62. Altman, J. D., Moss, P. A., Goulder, P. J., Barouch, D. H., McHeyzer-Williams, M. G., Bell, J. I., McMichael, A. J. and Davis, M. M., Phenotypic analysis of antigen-specific T lymphocytes. Science 1996. 274: 94-96.
63. Kearney, E. R., Pape, K. A., Loh, D. Y. and Jenkins, M. K., Visualization of peptide-specific T cell immunity and peripheral tolerance induction in vivo. Immunity 1994. 1: 327-339.
64. + T cells during an acute virus infection. Immunity 1998. 8: 167-175.
65. Sallusto, F., Geginat, J. and Lanzavecchia, A., Central memory and effector memory T cell subsets: function, generation, and maintenance. Annu. Rev. Immunol. 2004. 22: 745-763.
66. Wherry, E. J., Teichgraber, V., Becker, T. C., Masopust, D., Kaech, S. M., Antia, R., von Andrian, U. H. and Ahmed, R., Lineage relationship and protective immunity of memory CD8 T cell subsets. Nat. Immunol. 2003. 4: 225-234.
67. Kaech, S. M., Hemby, S., Kersh, E. and Ahmed, R., Molecular and functional profiling of memory CD8 T cell differentiation. Cell 2002. 111: 837-851.
68. Williams, M. A. and Bevan, M. J., Effector and memory CTL differentiation. Annu. Rev. Immunol. 2007. 25: 171-192.
69. Shin, H. and Wherry, E. J., CD8 T cell dysfunction during chronic viral infection. Curr. Opin. Immunol. 2007. 19: 408-415.
70. Barber, D. L., Wherry, E. J., Masopust, D., Zhu, B., Allison, J. P., Sharpe, A. H., Freeman, G. J. and Ahmed, R., Restoring function in exhausted CD8 T cells during chronic viral infection. Nature 2006. 439: 682-687.
71. Day, C. L., Kaufmann, D. E., Kiepiela, P., Brown, J. A., Moodley, E. S., Reddy, S., Mackey, E. W. et al., PD-1 expression on HIV-specific T cells is associated with T-cell exhaustion and disease progression. Nature 2006. 443: 350-354.
72. Trautmann, L., Janbazian, L., Chomont, N., Said, E. A., Gimmig, S., Bessette, B., Boulassel, M. R. et al., Upregulation of PD-1 expression on HIV-specific CD8 + T cells leads to reversible immune dysfunction. Nat. Med. 2006. 12: 1198-1202.
73. + T cell survival in HrV infection. J. Exp. Med. 2006. 203: 2281-2292.
74. Autran, B., Carcelain, G., Combadiere, B. and Debre, P., Therapeutic vaccines for chronic infections. Science 2004. 305: 205-208.
75. Burnet, F. M., Genes, Dreams, and Realities. MTII, Oxford, UK 1971
76. Masopust, D., Kaech, S. M., Wherry, E. J. and Ahmed, R., The role of programming in memory T-cell development. Curr. Opin. Immunol. 2004. 16: 217-225.