VII International Congress Of Reproductive Immunology, New Delhi, 27-30 October 1998: Expression and localization of the Th2-type cytokine interleukin-13 and its receptor in the placenta during human pregnancy

American Journal of Reproductive Immunology

Volumn 40, Issue 4, 1998, Pages 283-290

  Dealtry, Gillian B ^a   Clark, Dawn E ^b   Sharkey, Andrew ^b   Charnock Jones, D Stephen ^b   Smith, Stephen K ^b  

^a UNIVERSITY OF ESSEX   (United Kingdom)

^b UNIVERSITY OF CAMBRIDGE   (United Kingdom)

Author keywords

Cytokine receptors; Cytokines; Th1 Th2; Trophoblast

Indexed keywords

CYTOKINE; INTERLEUKIN 13; INTERLEUKIN 13 RECEPTOR; MESSENGER RNA; COMPLEMENTARY DNA; IL13RA1 PROTEIN, HUMAN; INTERLEUKIN 13 RECEPTOR ALPHA1; INTERLEUKIN RECEPTOR;

CONFERENCE PAPER; CYTOTROPHOBLAST; FEMALE; FIRST TRIMESTER PREGNANCY; GENE EXPRESSION; HELPER CELL; HUMAN; HUMAN TISSUE; IMMUNOFLUORESCENCE TEST; IMMUNOHISTOCHEMISTRY; IN SITU HYBRIDIZATION; LEUKOCYTE; PLACENTA; PREGNANCY; PRIORITY JOURNAL; PROTEIN EXPRESSION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SECOND TRIMESTER PREGNANCY; SYNCYTIOTROPHOBLAST; THIRD TRIMESTER PREGNANCY; ARTICLE; FLUORESCENT ANTIBODY TECHNIQUE; GENETICS; METABOLISM; TROPHOBLAST;

DNA, COMPLEMENTARY; FEMALE; FLUORESCENT ANTIBODY TECHNIQUE; HUMANS; IMMUNOHISTOCHEMISTRY; IN SITU HYBRIDIZATION; INTERLEUKIN-13; INTERLEUKIN-13 RECEPTOR ALPHA1 SUBUNIT; PLACENTA; PREGNANCY; PREGNANCY TRIMESTER, FIRST; PREGNANCY TRIMESTER, SECOND; PREGNANCY TRIMESTER, THIRD; RECEPTORS, INTERLEUKIN; RECEPTORS, INTERLEUKIN-13; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; TROPHOBLASTS;

EID: 0032185606     PISSN: 10467408     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1600-0897.1998.tb00419.x     Document Type: Conference Paper

References (39)

1. Sargent I: Maternal and fetal immune responses during pregnancy. Exp Clin Immunogenet 1993; 10:85-102.
2. Clarke AG, Kendall MD: The thymus in pregnancy - The interplay of neural, endocrine and immune influences. Immunol Today 1994; 15:545-551.
3. Wegmann TG, Lin H, Guilbert L, Mosmann TR: Bidirectional cytokine interactions in the maternal-fetal relationship - Is successful pregnancy a Th2 phenomenon? Immunol Today 1993; 14:353-356.
4. Sharkey A: Cytokines and embryo/endometrial interactions. Reprod Med Rev 1995; 4:87.
5. Robertson SA, Seamark RF, Guilbert LJ, Wegmann TG: The role of cytokines in gestation. Crit Rev Immunol 1994; 14:239-292.
6. Guilbert L: There is a bias against type 1 (inflammatory) cytokine expression and function in pregnancy. J Reprod Immunol 1996; 32:105-110.
7. Varner MW: Autoimmune disorders and pregnancy. Semin Perinatol 1991; 15:238-250.
8. Krishnan L, Guilbert LJ, Russell AS, Wegmann TG, Mosmann TR, Belosevic M: Pregnancy impairs resistance of C57BL/6 mice to Leishmania major infection and causes decreased antigen-specific IFN-γ responses and increased production of T helper 2 cytokines. J Immunol 1996a; 156:644-662.
9. Lin H, Mosmann TR, Guilbert L, Tuntipopipat S, Wegmann TG: Synthesis of T helper 2-type cytokines at the maternal-fetal interface. J Immunol 1993; 151:4562-4573.
10. Chaouat G, Meliani AA, Martal J, Raghupathy R, Elliot J, Mosmann TR, Wegmann TG: IL-10 prevents naturally occurring fetal loss in the CBA x DBA/2 mating combination, and local defect in IL-10 production in this abortion-prone combination is corrected by in vivo injection of IFN Tau. J Immunol 1995; 154:4261-4268.
11. King A, Jokhi PP, Sharkey AM, Loke YW: Screening for cytokine mRNA in human villous and extravillous trophoblasts using the reverse-transcriptase polymerase chain reaction (RT-PCR). Cytokine 1995; 7:364-371.
12. Stallmach T, Hebisch G, Joller-Jemelka HI, Orban P, Schwaller J, Engelmann M: Cytokine production and visualised effects in the feto-maternal unit. Lab Invest 1995; 73:384-392.
13. Loke YW, King A: Human implantation. In Cell Biology and immunology. Cambridge, UK, Cambridge University Press.
14. Hillier SL, Witkin SS, Krohn MA, Watts DH, Kiviat NB, Eschenbach DA: The relationship of amniotic fluid cytokines and preterm delivery, amniotic fluid infection, histological chorioamnionitis, and chorioamnion infection. Obstet Gynecol 1993; 81:941-948.
15. Saito S, Kasahara T, Kato Y, Ishihara Y, Ichijo M: Elevation of amniotic fluid interleukin 6 (IL-6), IL-8 and granulocyte colony stimulating factor (G-CSF) in term and preterm parturition. Cytokine 1993; 5:81-88.
16. Piccinni MP, Giudizi MG, Bagiotti R, Beloni L, Giannarini L, Sampognaro S, Parronchi P, Manetti R, Annunziato F, Livi C, Romagnani S, Maggi E: Progesterone favours the development of human T-helper cells producing Th2-type cytokines and promotes both IL-4 production and membrane CD30 expression in established Th1 cell clones. J Immunol 1995; 155:128-133.
17. Roth I, Corry DB, Lochsley RM, Abrams JS, Litton MJ, Fisher SJ: Human placental cyto-trophoblasts produce the immunosuppressive cytokine interleukin-10. J Exp Med 1996; 184:539-548.
18. Greig PC, Herbert WNP, Robinette BL, Teot LA: Amniotic-fluid interleukin-10 concentrations increase through pregnancy and are elevated in patients with preterm labor associated intra-uterine infection. Am J Obstet Gynecol 1995; 173:1223-1227.
19. Krasnow JS, Tollerud DJ, Naus G, DeLoia JA: Endometrial Th2 cytokine expression throughout the menstrual cycle and early pregnancy. Human Reprod 1996; 11:1747-1754.
20. Jones CA, Williams KA, Finlay Jones JJ, Hart PH: Interleukin-4 production by human amnion epithelial-cells and regulation of its activity by glycosaminoglycan binding. Biol Reprod 1995; 52:839-847.
21. McKenzie AN, Li X, Largaespada DA, Sato A, Kaneda A, Zurawski SM, Doyle EL, Milatovich A, Francke U, Copeland NG, Jenkins NA, Zurawski G: Structural comparison and chromosomal localisation of the human and mouse IL-13 genes. J Immunol 1993; 150:5436-5444.
22. Minty A, Chalon P, Deroq J-M, Dumont X, Guillemot J-C, Kaghad M, Labit C, Leplatois P, Liauzun P, Miloux B, Minty C, Casellas P, Loisin G, Lupker J, Shire D, Ferrara P, Caput D: Interleukin 13 is a new lymphokine regulating inflammatory and immune response. Nature 1993; 362:248-250.
23. Burd PR, Thompson WC, Max EE, Mills FC: Activated mast cells produce interleukin-13. J Exp Med 1995; 181:1373-1380.
24. Zurawski, G, de Vries JE: Interleukin 13, an interleukin 4-like cytokine that acts on monocytes and B cells, but not on T cells. Immunol Today 1994; 15:19-26.
25. Murata T, Noguchi PD, Puri RK: IL-13 induces phosphorylation and activation of JAK2 Janus kinase in human colon carcinoma cell lines. J Immunol 1996; 156:2972.
26. Sironi M, Sciacca FL, Matteucci C, Conni M, Vecchi A, Bernasconi S, Minty A, Caput D, Ferrara P, Colotta F, Mantovani A: Regulation of endothelial and mesothelial cell function by interleukin-13: selective induction of vascular cell adhesion molecule-1 and amplification of interleukin-6 production. Blood 1994; 84:1913-1921.
27. Lin JX, Migone TS, Tsang M, Friedmann M, Weatherbee JA, Zhou L, Yamauchi A, Bloom ET, Mietz J, John S, Leonard WJ: The role of shared receptor motifs and common STAT proteins in the generation of cytokine pleiotropy and redundancy by IL-2. IL-4, IL-7, IL-13 and IL-15. Immunity 1995; 2:331-339.
28. de Moraes-Pinto MI, Vince GS, Flanagan BF, Hart CA, Johnson PM: Localisation of IL-4 and IL-4 receptors in human term placenta, decidua and amniochorionic membranes. Immunol 1997; 90:87-94.
29. Aman MJ, Tayebi N, Obiri NI, Puri RK, Modi WS, Leonard WJ: cDNA cloning and characterisation of the human interleukin-13 receptor-alpha chain. J Biol Chem 1996; 271:29265-29270.
30. Chomczynski P, Sacchi N: Single-step method of RNA isolation by acid guanidium thiocyanate-phenol-chloroform extraction. Anal Biochem 1987; 162:156-159.
31. Sharkey AM, Charnock-Jones DS, Boocock CA, Brown KD, Smith SK: Expression of mRNA for vascular endothelial growth factor in human placenta. J Reprod Fertil 1993; 99:609-615.
32. Sharkey AM, Dellow K, Blayney M, Macnamee M, Charnock-Jones DS, Smith SK: Stage-specific expression of cytokine and receptor messenger ribonucleic acids in human preimplantation embryos. Biol Reprod 1995; 53:974-981.
33. Clark DE, Smith SK, Sharkey AM, Charnock-Jones DS: Localization of VEGF and expression of its receptors flt and KDR in human placenta throughout pregnancy. Human Reprod 1996; 11:1090-1098.
34. Doherty TM, Kastelein R, Menon S, Andrade S, Coffman RL: Modulation of murine macrophage function by IL-13. J Immunol 1993; 151:7151-7160.
35. Krishnan L, Guilbert LJ, Wegmann TG, Belosevic M, Mosmann TR: T helper 1 response against Leishmania major in pregnant C57BL/6 mice increases implantation failure and fetal resorptions. J Immunol 1996b; 156:653-662.
36. Vince GS, Johnson PM: Immunobiology of human uterplacental macrophages - friend and foe. J Reprod Immunol 1996; 32:10104.
37. Charnock-Jones DS, Sharkey AM, Boocock CA, Ahmed A, Plevin R, Ferrara N, Smith SK: Vascular endothelial growth factor receptor localisation and activation in human trophoblast and choriocarcinoma cells. Biol Reprod 1994; 51:524-530.
38. de Waal Malefyt R, Figdor CG, Huijbens R, Mohan-Peterson S, Bennet B, Culpepper J, Dang W, Zurawski G, de Vries JE: Effect of IL-13 on phenotype, cytokine production, and cytotoxic function of human monocytes. J Immunol 1993; 151:6370-6381.
39. Endo T, Ogushi F, and Sone S: LPS-dependent cyclo-oxygenase-2 induction in human monocytes is down regulated by IL-13, but not by IFN-γ. J Immunol 1996; 156:2240-2246.