GABA transporter type 1 (GAT-1) uptake inhibition reduces stimulated aspartate and glutamate release in the dorsal spinal cord in vivo via different GABAergic mechanisms

Neuropharmacology

Volumn 53, Issue 8, 2007, Pages 975-981

  Smith, C G S ^a   Bowery, N G ^a   Whitehead, K J ^a  

^a Medical School   (United Kingdom)

Author keywords

Analgesia; Excitatory amino acid; GABA re uptake; GAT 1; Microdialysis; Spinal cord

Indexed keywords

1 [2 (BENZHYDRYLIDENEAMINOOXY)ETHYL] 1,2,5,6 TETRAHYDRO 3 PYRIDINECARBOXYLIC ACID; 4 AMINOBUTYRIC ACID CARRIER; 5,5 DIMETHYL 2 MORPHOLINEACETIC ACID; ASPARTIC ACID; BICUCULLINE; GABA TRANSPORTER TYPE 1; GLUTAMIC ACID; GLYCINE; POTASSIUM; UNCLASSIFIED DRUG;

ANESTHESIA; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; DEPOLARIZATION; DIALYSIS; DRUG EFFECT; DRUG MECHANISM; EVOKED RESPONSE; MALE; MICRODIALYSIS; MOLECULAR MECHANICS; NEUROTRANSMISSION; NOCICEPTION; NONHUMAN; PRIORITY JOURNAL; PROTEIN FUNCTION; RAT; SPINAL CORD;

ANALYSIS OF VARIANCE; ANIMALS; ASPARTIC ACID; BICUCULLINE; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG COMBINATIONS; GABA PLASMA MEMBRANE TRANSPORT PROTEINS; GAMMA-AMINOBUTYRIC ACID; GLUTAMIC ACID; MALE; MICRODIALYSIS; MORPHOLINES; NEUROTRANSMITTER UPTAKE INHIBITORS; NIPECOTIC ACIDS; OXIMES; POTASSIUM CHLORIDE; RATS; RATS, WISTAR; SPINAL CORD;

EID: 36248932166     PISSN: 00283908     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neuropharm.2007.09.008     Document Type: Article

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