Metastatic suppressor genes inactivated by aberrant methylation in gastric cancer

World Journal of Gastroenterology

Volumn 13, Issue 43, 2007, Pages 5692-5698

  Wang, Jian Feng ^a   Dai, Dong Qiu ^a  

^a CHINA MEDICAL UNIVERSITY   (China)

Author keywords

DNA methylation; Gastric cancer; Gene PTPRG; Methylated CpG islands amplification; Representational difference analysis

Indexed keywords

5 AZA 2' DEOXYCYTIDINE; GENE PRODUCT; MESSENGER RNA; PROTEIN PTPRG; UNCLASSIFIED DRUG;

AMINO ACID SEQUENCE; ARTICLE; BIOINFORMATICS; DNA METHYLATION; DRUG MECHANISM; GENE EXPRESSION REGULATION; GENE LOCATION; GENETIC SCREENING; HUMAN; LYMPH NODE METASTASIS; MOLECULAR CLONING; POLYMERASE CHAIN REACTION; PROMOTER REGION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SEQUENCE ANALYSIS; STOMACH CANCER;

EID: 36248930484     PISSN: 10079327     EISSN: None     Source Type: Journal    
DOI: 10.3748/wjg.v13.i43.5692     Document Type: Article

References (30)

1. Toyota M, Itoh F, Imai K. DNA methylation and gastrointestinal malignancies: functional consequences and clinical implications. J Gastroenterol 2000; 35: 727-734
2. Rashid A, Shen L, Morris JS, Issa JP, Hamilton SR. CpG island methylation in colorectal adenomas. Am J Pathol 2001; 159: 1129-1135
3. Cowled P, Kanter I, Leonardos L, Jackson P. Uroplakin Ib, gene transcription in urothelial tumor cells is regulated by CpG methylation. Neoplasia 2005; 7: 1091-1103
4. Teodoridis JM, Hall J, Marsh S, Kannall HD, Smyth C, Curto J, Siddiqui N, Gabra H, McLeod HL, Strathdee G, Brown R. CpG island methylation of DNA damage response genes in advanced ovarian cancer. Cancer Res 2005; 65: 8961-8967
5. Costello JF, Fruhwald MC, Smiragha. DJ, Rush LJ, Robertson GP, Gao X, Wright FA, Feramisco JD, Peltomaki P, Lang JC, Schuller DE, Yu L, Bloomfield CD, Caligiuri MA, Yates A, Nishikawa R, Su Huang H, Petrelli NJ, Zhang X, O'Dorisio MS, Held WA, Cavenee WK, Plass C. Aberrant CpG-island methylation has non-random and tumour-type-specific patterns. Nat Genet 2000; 24: 132-138
6. Toyota M, Ahuja N, Suzuki H, Itoh F, Ohe-Toyota M, Imai K, Baylin SB, Issa JP. Aberrant methylation in gastric cancer associated with the CpG island methylator phenotype. Cancer Res 1999; 59: 5438-5442
7. Toyota M, Ho C, Ahuja N, Jair KW, Li Q, Ohe-Toyota M, Baylin SB, Issa JP. Identification of differentially methylated sequences in colorectal cancer by methylated CpG island amplification. Cancer Res 1999; 59: 2307-2312
8. Lisitsyn N, Lisitsyn N, Wigler M. Cloning the differences between two complex genomes. Science 1993; 259: 946-951
9. Esteller M, Hamilton SR, Burger PC, Baylin SB, Herman JG. Inactivation of the DNA repair gene O6-methylguanine-DNA methyltransferase by promoter hypermethylation is a common event in primary human neoplasia. Cancer Res 1999; 59: 793-797
10. Siegfried Z, Cedar H. DNA methylation: a molecular lock. Curr Biol 1997; 7: R305-R307
11. Tycko B. Epigenetic gene silencing in cancer. J Clin Invest 2000; 105: 401-407
12. Catteau A, Harris WH, Xu CF, Solomon E. Methylation of the BRCA1 promoter region in sporadic breast and ovarian cancer: correlation with disease characteristics. Oncogene 1999; 18: 1957-1965
13. Jaenisch R, Bird A. Epigenetic regulation of gene expression: how the genome integrates intrinsic and environmental signals. Nat Genet 2003; 33 Suppl: 245-254
14. Dong C, Yoon W, Goldschmidt-Clermont PJ. DNA methylation and atherosclerosis. J Nutr 2002; 132: 2406S-2409S
15. Robertson KD, Jones PA. DNA methylation: past, present and future directions. Carcinogenesis 2000; 21: 461-467
16. Choi IS, Wu TT. Epigenetic alterations in gastric carcinogenesis. Cell Res 2005; 15: 247-254
17. Issa JP. Epigenetic variation and human disease. J Nutr 2002; 132: 2388S-2392S
18. Wang Z, Shen D, Parsons DW, Bardelli A, Sager J, Szabo S, Ptak J, Silliman N, Peters BA, van der Heijden MS, Parmigiani G, Yan H, Wang TL, Riggins G, Powell SM, Willson JK, Markowitz S, Kinzler KW, Vogelstein B, Velculescu VE. Mutational analysis of the tyrosine phosphatome in colorectal cancers. Science 2004; 304: 1164-1166
19. van Doorn R, Zoutman WH, Dijkman R, de Menezes RX, Commandeur S, Mulder AA, van der Velden PA, Vermeer MH, Willemze R, Yan PS, Huang TH, Tensen CP. Epigenetic profiling of cutaneous T-cell lymphoma: promoter hypermethylation of multiple tumor suppressor genes including BCL7a, PTPRG, and p73. J Clin Oncol 2005; 23: 3886-3896
20. Van Poucke M, Yerle M, Chardon P, Jacobs K, Genet C, Mattheeuws M, Van Zeveren A, Peelman LJ. A refined comparative map between porcine chromosome 13 and human chromosome 3. Cytogenet Genome Res 2003; 102: 133-138
21. Kholodnyuk ID, Szeles A, Yang Y, Klein G, Imreh S. Inactivation of the human fragile histidine triad gene at 3p14.2 in monochromosomal human/mouse microcell hybrid-derived severe combined immunodeficient mouse tumors. Cancer Res 2000; 60: 7119-7125
22. Matsuyama A, Shiraishi T, Trapasso F, Kuroki T, Alder H, Mori M, Huebner K, Croce CM. Fragile site orthologs FHIT/FRA3B and Fhit/Fra14A2: evolutionarily conserved but highly recombinogenic. Proc Natl Acad Sci USA 2003; 100: 14988-14993
23. Motiwala T, Ghoshal K, Das A, Majumder S, Weichenhan D, Wu YZ, Holman K, James SJ, Jacob ST, Plass C. Suppression of the protem. tyrosme phosphatase receptor type O gene (PTPRO) by methylation in hepatocellular carcinomas. Oncogene 2003; 22: 6319-6331
24. Wang Z, Shen D, Parsons DW, Bardelli A, Sager J, Szabo S, Ptak J, Silliman N, Peters BA, van der Heijden MS, Parmigiani G, Yan H, Wang TL, Riggins G, Powell SM, Willson JK, Markowitz S, Kinzler KW, Vogelstein B, Velculescu VE. Mutational analysis of the tyrosine phosphatome in colorectal cancers. Science 2004; 304: 1164-1166
25. LaForgia S, Morse B, Levy J, Barnea G, Cannizzaro LA, Li F, Nowell PC, Boghosian-Sell L, Glick J, Weston A. Receptor protein-tyrosine phosphatase gamma is a candidate tumor suppressor gene at human chromosome region 3p21. Proc Natl Acad Sci USA 1991; 88: 5036-5040
26. Esteller M, Hamilton SR, Burger PC, Baylin SB, Herman JG. Inactivation of the DNA repair gene O6-methylguanine-DNA methyltransferase by promoter hypermethylation is a common event in primary human neoplasia. Cancer Res 1999; 59: 793-797
27. Herman JG, Graff JR, Myohanen S, Nelkin BD, Baylin SB. Methylation-specific PCR: a novel PCR assay for methylation status of CpG islands. Proc Natl Acad Sci USA 1996; 93: 9821-9826
28. Deng G, Chen A, Hong J, Chae HS, Kim YS. Methylation of CpG in a small region of the hMLH1 promoter invariably correlates with the absence of gene expression. Cancer Res 1999; 59: 2029-2033
29. Fang JY, Lu J, Chen YX, Yang L. Effects of DNA methylation on expression of tumor suppressor genes and proto-oncogene in human colon cancer cell lines. World J Gastroenterol 2003; 9: 1976-1980
30. Liu LH, Xiao WH, Liu WW. Effect of 5-Aza-2′-deoxycytidine on the P16 tumor suppressor gene in hepatocellular carcinoma cell line HepG2. World J Gastroenterol 2001; 7: 131-135