Gender difference in ICER Iγ transgenic diabetic mouse

Bioscience, Biotechnology and Biochemistry

Volumn 71, Issue 8, 2007, Pages 1920-1926

  Inada, Akari ^a,b   Arai, Hidenori ^a   Nagai, Kojiro ^a   Miyazaki, Jun Ichi ^c   Yamada, Yuichiro ^b   Seino, Yutaka ^b,d   Fukatsu, Atsushi ^a  

^a KYOTO UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^b KYUSHU UNIVERSITY   (Japan)

^c OSAKA UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^d KANSAI ELECTRIC POWER CO   (Japan)

Author keywords

Diabetic model; Diabetic nephropathy; Gender difference

Indexed keywords

INSULIN; MEDICAL PROBLEMS; METABOLISM; RATS; SYNTHESIS (CHEMICAL);

DIABETIC MODEL; DIABETIC NEPHROPATHY; GENDER DIFFERENCE; NEPHROPATHY;

BIOTECHNOLOGY;

CYCLIC AMP RESPONSIVE ELEMENT MODULATOR; GLUCOSE; SEX HORMONE;

AGE; ANIMAL; ANIMAL MODEL; ARTICLE; DIABETIC NEPHROPATHY; EXPERIMENTAL DIABETES MELLITUS; FEMALE; GENE EXPRESSION REGULATION; GENETICS; MALE; METABOLISM; MOUSE; PHYSIOLOGY; SEX DIFFERENCE; TRANSGENIC MOUSE;

AGE FACTORS; ANIMALS; CYCLIC AMP RESPONSE ELEMENT MODULATOR; DIABETES MELLITUS, EXPERIMENTAL; DIABETIC NEPHROPATHIES; FEMALE; GENE EXPRESSION REGULATION; GLUCOSE; GONADAL STEROID HORMONES; MALE; MICE; MICE, TRANSGENIC; MODELS, ANIMAL; SEX FACTORS;

MUS; MUS MUSCULUS;

EID: 36148992938     PISSN: 09168451     EISSN: 13476947     Source Type: Journal    
DOI: 10.1271/bbb.70116     Document Type: Article

References (26)

1. Lamothe, B., Duvillie, B., Cordonnier, N., Baudry, A., Saint-Just, S., Bucchini, D., Jami, J., and Joshi, R. L., Genetic manipulation of insulin action and beta-cell function in mice. Mol. Cell Biochem., 182, 161-168 (1998).
2. Lee, J. Y., Ristow, M., Lin, X., White, M. F., Magnuson, M. A., and Henninghousen, L., RIP-Cre revisited, evidence for impairments of pancreatic beta-cell function. J. Biol. Chem., 281, 2649-2653 (2006).
3. Breyer, M. D., Bottinger, E., Brosius, F. C., 3rd, Coffman, T. M., Harris, R. C., Heilig, C. W., and Sharma, K., AMDCC, Mouse models of diabetic nephropathy. J. Am. Soc. Nephrol., 16, 27-45 (2005).
4. Jhala, U. S., Canettieri, G., Screaton, R. A., Kulkarni, R. N., Krajewski, S., Reed, J., Walker, J., Lin, X., White, M., and Montminy, M., cAMP promotes pancreatic beta-cell survival via CREB-mediated induction of IRS2. Genes Dev., 17, 1575-1580 (2003).
5. Gorogawa, S., Fujitani, Y., Kaneto, H., Hazama, Y., Watada, H., Miyamoto, Y., Takeda, K., Akira, S., Magnuson, M. A., Yamasaki, Y., Kajimoto, Y., and Hori, M., Insulin secretory defects and impaired islet architecture in pancreatic beta-cell-specific STAT3 knockout mice. Biochem. Biophys. Res. Commun., 319, 1159-1170 (2004).
6. Wang, L., Coffinier, C., Thomas, M. K., Gresh, L., Eddu, G., Manor, T., Levitsky, L. L., Yaniv, M., and Rhoads, D. B., Selective deletion of the Hnf1beta (MODY5) gene in beta-cells leads to altered gene expression and defective insulin release. Endocrinology, 145, 3941-3949 (2004).
7. Haseyama, T., Fujita, T., Hirasawa, F., Tsukada, M., Wakui, H., Komatsuda, A., Ohtani, H., Miura, A. B., Imai, H., and Koizumi, A., Complications of IgA nephropathy in a non-insulin-dependent diabetes model, the Akita mouse. Tohoku J. Exp. Med., 198, 233-244 (2002).
8. Inada, A., Hamamoto, Y., Tsuura, Y., Miyazaki, J., Toyokuni, S., Ihara, Y., Nagai, K., Yamada, Y., Bonner-Weir, S., and Seino, Y., Overexpression of inducible cyclic AMP early repressor inhibits transactivation of genes and cell proliferation in pancreatic β cells. Mol. Cell. Biol., 24, 2831-2841 (2004).
9. Molina, C. A., Foulkes, N. S., Lalli, E., and Sassone-Corsi, P., Inducibility and negative autoregulation of CREM: an alternative promoter directs the expression of ICER, an early response repressor. Cell, 75, 875-886 (1993).
10. Inada, A., Yamada, Y., Someya, Y., Kubota, A., Yasuda, K., Ihara, Y., Kagimoto, S., Kuroe, A., Tsuda, K., and Seino, Y., Transcriptional repressors are increased in pancreatic islets of type 2 diabetic rats. Biochem. Biophys. Res. Commun., 253, 712-718 (1998).
11. Foulkes, N. S., Borrelli, E., and Sassone-Corsi, P., CREM gene: use of alternative DNA-binding domains generates multiple antagonists of cAMP-induced transcription. Cell, 64, 739-749 (1991).
12. Inada, A., Someya, Y., Yamada, Y., Ihara, Y., Kubota, A., Ban, N., Watanabe, R., Tsuda, K., and Seino, Y., The cyclic AMP response element modulator family regulates the insulin gene transcription by interacting with transcription factor IID. J. Biol. Chem., 274, 21095-21103 (1999).
13. Inada, A., Weir, G. C., and Bonner-Weir, S., Induced ICER Iγ down-regulates cyclin A expression and cell proliferation in insulin-producing β cells. Biochem. Biophys. Res. Commun., 329, 925-929 (2005).
14. Zhou, Y. P., Marlen, K., Palma, J. F., Schweitzer, A., Reilly, L., Gregoire, F. M., Xu, G. G., Blume, J. E., and Johnson, J. D., Overexpression of repressive cAMP response element modulators in high glucose and fatty acid-treated rat islets: a common mechanism for glucose toxicity and lipotoxicity? J. Biol. Chem., 278, 51316-51323 (2003).
15. Inada, A., Nagai, K., Arai, H., Miyazaki, J., Nomura, K., Kanamori, H., Toyokuni, S., Yamada, Y., Bonner-Weir, S., Weir, G. C., Fukatsu, A., and Seino, Y., Establishment of a diabetic mouse model with progressive diabetic nephropathy. Am. J. Pathol., 167, 327-336 (2005).
16. Le May, C., Chu, K., Hu, M., Ortega, C. S., Simpson, E. R., Korach, K. S., Tsai, M. J., and Mauvais-Jarvis, F., Estrogens protect pancreatic beta-cells from apoptosis and prevent insulin-deficient diabetes mellitus in mice. Proc. Natl. Acad. Sci. USA, 103, 9232-9237 (2006).
17. Borissova, A. M., Tankova, T., Kirilov, G., and Koev, D., Gender-dependent effect of ageing on peripheral insulin action. Int. J. Clin. Pract., 59, 422-426 (2005).
18. Ismail, N., Becker, B., Strzelczyk, P., and Ritz, E., Renal disease and hypertension in noninsulin-dependent diabetes mellitus. Kidney Int., 55, 1-28 (1999).
19. Silbiger, S., and Neugarten, J., The impact of gender on the progression of chronic renal disease. Am. J. Kidney Dis., 25, 515-533 (1995).
20. Neugarten, J., and Silbiger, S., Effect of sex hormones on mesangial cells. Am. J. Kidney Dis., 26, 147-151 (1995).
21. Silbiger, S., and Neugarten, J., The role of gender in the progression of renal disease. Adv. Ren. Replace Ther., 10, 3-14 (2003).
22. Kang, A. K., and Miller, J. A., Impact of gender on renal disease: the role of the rennin angiotensin system. Clin. Invest. Med., 26, 38-44 (2003).
23. Guccione, M., Silbiger, S., Lei, J., and Neugarten, J., Estradiol upregulates mesangial cell MMP-2 activity via the transcription factor AP-2. Am. J. Physiol. Renal Physiol., 282, F164-169 (2002).
24. Fornoni, A., Striker, L. J., Zheng, F., and Striker, G. E., Reversibility of glucose-induced changes in mesangial cell extracellular matrix depends on the genetic background. Diabetes, 51, 499-505 (2002).
25. Del Prete, D., Anglani, F., Forino, M., Ceol, M., Fioretto, P., Nosadini, R., Baggio, B., and Gambaro, G., Downregulation of glomerular matrix metalloproteinase-2 gene in human NIDDM. Diabetologia, 40, 1449-1454 (1997).
26. Death, A. K., Fisher, E. J., McGrath, K. C., and Yue, D. K., High glucose alters matrix metalloproteinase expression in two key vascular cells: potential impact on atherosclerosis in diabetes. Atherosclerosis, 168, 263-269 (2003).