-
1
-
-
0017199306
-
Selective in vitro growth of T lymphocytes from normal human bone marrow
-
Morgan D.A., Ruscetti F.W., and Gallo R. Selective in vitro growth of T lymphocytes from normal human bone marrow. Science 193 (1976) 1007-1008
-
(1976)
Science
, vol.193
, pp. 1007-1008
-
-
Morgan, D.A.1
Ruscetti, F.W.2
Gallo, R.3
-
2
-
-
0023907493
-
Interleukin-2: inception, impact, and implications
-
Smith K.A. Interleukin-2: inception, impact, and implications. Science 240 (1988) 1169-1176
-
(1988)
Science
, vol.240
, pp. 1169-1176
-
-
Smith, K.A.1
-
3
-
-
0023083460
-
In vivo and in vitro activation of NK cytotoxicity with IL-2
-
Ibayashi Y., Tokuda Y., Saks E.R., Sarna G.P., and Golub S.H. In vivo and in vitro activation of NK cytotoxicity with IL-2. Prog. Clin. Biol. Res. 244 (1987) 275-285
-
(1987)
Prog. Clin. Biol. Res.
, vol.244
, pp. 275-285
-
-
Ibayashi, Y.1
Tokuda, Y.2
Saks, E.R.3
Sarna, G.P.4
Golub, S.H.5
-
4
-
-
0027361937
-
Activation of human monocyte/macrophage cytotoxicity by IL-2/IFN gamma is linked to increased expression of an antitumor receptor with specificity for acetylated mannose
-
Zhu H.G., Zollner T.M., Klein-Franke A., and Anderer F.A. Activation of human monocyte/macrophage cytotoxicity by IL-2/IFN gamma is linked to increased expression of an antitumor receptor with specificity for acetylated mannose. Immunol. Lett. 38 (1993) 111-119
-
(1993)
Immunol. Lett.
, vol.38
, pp. 111-119
-
-
Zhu, H.G.1
Zollner, T.M.2
Klein-Franke, A.3
Anderer, F.A.4
-
5
-
-
0026436889
-
Activation of neutrophils by interleukins-1 and -2 and tumor necrosis factors
-
Ferrante A. Activation of neutrophils by interleukins-1 and -2 and tumor necrosis factors. Immunol. Ser. 57 (1992) 417-436
-
(1992)
Immunol. Ser.
, vol.57
, pp. 417-436
-
-
Ferrante, A.1
-
6
-
-
0028171479
-
The clinical experience with interleukin-2 in cancer therapy
-
Dillman R.O. The clinical experience with interleukin-2 in cancer therapy. Cancer Biother. 9 (1994) 183-209
-
(1994)
Cancer Biother.
, vol.9
, pp. 183-209
-
-
Dillman, R.O.1
-
7
-
-
1842633505
-
Application of IL-2 and other cytokines in renal cancer
-
McDermott D.F., and Atkins M.B. Application of IL-2 and other cytokines in renal cancer. Expert Opin. Biol. Ther. 4 (2004) 455-468
-
(2004)
Expert Opin. Biol. Ther.
, vol.4
, pp. 455-468
-
-
McDermott, D.F.1
Atkins, M.B.2
-
9
-
-
0025190966
-
Interferon-gamma: producer cells, activation stimuli, and molecular genetic regulation
-
Young H.A., and Hardy K.J. Interferon-gamma: producer cells, activation stimuli, and molecular genetic regulation. Pharmacol. Ther. 45 (1990) 137-151
-
(1990)
Pharmacol. Ther.
, vol.45
, pp. 137-151
-
-
Young, H.A.1
Hardy, K.J.2
-
10
-
-
0030586560
-
A direct role for IFN-gamma in regulation of Th1 cell development
-
Bradley L.M., Dalton D.K., and Croft M. A direct role for IFN-gamma in regulation of Th1 cell development. J. Immunol. 157 (1996) 1350-1358
-
(1996)
J. Immunol.
, vol.157
, pp. 1350-1358
-
-
Bradley, L.M.1
Dalton, D.K.2
Croft, M.3
-
11
-
-
0029671118
-
Roles of IFN-gamma and IFN-alpha in IL-12-induced T helper cell-1 development
-
Wenner C.A., Guler M.L., Macatonia S.E., O'Garra A., and Murphy K.M. Roles of IFN-gamma and IFN-alpha in IL-12-induced T helper cell-1 development. J. Immunol. 156 (1996) 1442-1447
-
(1996)
J. Immunol.
, vol.156
, pp. 1442-1447
-
-
Wenner, C.A.1
Guler, M.L.2
Macatonia, S.E.3
O'Garra, A.4
Murphy, K.M.5
-
12
-
-
0028028416
-
Interferon-gamma and host antimicrobial defense: current and future clinical applications
-
Murray H.W. Interferon-gamma and host antimicrobial defense: current and future clinical applications. Am. J. Med. 97 (1994) 459-467
-
(1994)
Am. J. Med.
, vol.97
, pp. 459-467
-
-
Murray, H.W.1
-
14
-
-
0025041035
-
Regulation of cellular gene expression by interferon-gamma: involvement of multiple pathways
-
Gupta S.L. Regulation of cellular gene expression by interferon-gamma: involvement of multiple pathways. Int. J. Cell Cloning 8 Suppl. 1 (1990) 92-102
-
(1990)
Int. J. Cell Cloning
, vol.8
, Issue.SUPPL. 1
, pp. 92-102
-
-
Gupta, S.L.1
-
15
-
-
0028142430
-
Regulation of MHC class II expression by interferon-gamma mediated by the transactivator gene CIITA
-
Steimle V., Siegrist C.A., Mottet A., Lisowska-Grospierre B., and Mach B. Regulation of MHC class II expression by interferon-gamma mediated by the transactivator gene CIITA. Science 265 (1994) 106-109
-
(1994)
Science
, vol.265
, pp. 106-109
-
-
Steimle, V.1
Siegrist, C.A.2
Mottet, A.3
Lisowska-Grospierre, B.4
Mach, B.5
-
16
-
-
0026046632
-
Interferon gamma for chronic granulomatous disease
-
Mouy R., Seger R., Bourquin J.P., Veber F., Blanche S., Griscelli C., and Fischer A. Interferon gamma for chronic granulomatous disease. N. Engl. J. Med. 325 (1991) 1516-1517
-
(1991)
N. Engl. J. Med.
, vol.325
, pp. 1516-1517
-
-
Mouy, R.1
Seger, R.2
Bourquin, J.P.3
Veber, F.4
Blanche, S.5
Griscelli, C.6
Fischer, A.7
-
17
-
-
0025744654
-
Recombinant interferon gamma treatment in non-small cell lung cancer. Antitumour effect and cardiotoxicity
-
Mattson K., Niiranen A., Pyrhonen S., Farkkila M., and Cantell K. Recombinant interferon gamma treatment in non-small cell lung cancer. Antitumour effect and cardiotoxicity. Acta Oncol. 30 (1991) 607-610
-
(1991)
Acta Oncol.
, vol.30
, pp. 607-610
-
-
Mattson, K.1
Niiranen, A.2
Pyrhonen, S.3
Farkkila, M.4
Cantell, K.5
-
18
-
-
5644300777
-
The phenomenology and treatment of interferon-induced depression
-
Loftis J.M., and Hauser P. The phenomenology and treatment of interferon-induced depression. J. Affect. Disord. 82 (2004) 175-190
-
(2004)
J. Affect. Disord.
, vol.82
, pp. 175-190
-
-
Loftis, J.M.1
Hauser, P.2
-
19
-
-
0027172965
-
Immunostimulants
-
Hadden J.W. Immunostimulants. Immunol. Today 14 (1993) 275-280
-
(1993)
Immunol. Today
, vol.14
, pp. 275-280
-
-
Hadden, J.W.1
-
20
-
-
0021214326
-
Levamisole as adjuvant to chemotherapy of ovarian cancer. Results of a randomized trial and 4-year follow-up
-
Khoo S.K., Whitaker S.V., Jones I.S., and Thomas D.A. Levamisole as adjuvant to chemotherapy of ovarian cancer. Results of a randomized trial and 4-year follow-up. Cancer 54 (1984) 986-990
-
(1984)
Cancer
, vol.54
, pp. 986-990
-
-
Khoo, S.K.1
Whitaker, S.V.2
Jones, I.S.3
Thomas, D.A.4
-
21
-
-
0029895837
-
Tucaresol increases oxygen affinity and reduces haemolysis in subjects with sickle cell anaemia
-
Arya R., Rolan P.E., Wootton R., Posner J., and Bellingham A.J. Tucaresol increases oxygen affinity and reduces haemolysis in subjects with sickle cell anaemia. Br. J. Haematol. 93 (1996) 817-821
-
(1996)
Br. J. Haematol.
, vol.93
, pp. 817-821
-
-
Arya, R.1
Rolan, P.E.2
Wootton, R.3
Posner, J.4
Bellingham, A.J.5
-
22
-
-
0026700475
-
Potentiation of immune responses in mice by a new inosine derivative-methyl inosine monophosphate (MIMP)
-
Sosa M., Saha A.R., Wang Y., Coto J., Giner-Sorolla A., Hadden E.M., and Hadden J.W. Potentiation of immune responses in mice by a new inosine derivative-methyl inosine monophosphate (MIMP). Int. J. Immunopharmacol. 14 (1992) 1259-1266
-
(1992)
Int. J. Immunopharmacol.
, vol.14
, pp. 1259-1266
-
-
Sosa, M.1
Saha, A.R.2
Wang, Y.3
Coto, J.4
Giner-Sorolla, A.5
Hadden, E.M.6
Hadden, J.W.7
-
23
-
-
0030867909
-
Synthesis and activity of 6-substituted purine linker amino acid immunostimulants
-
Zacharie B., Gagnon L., Attardo G., Connolly T.P., St-Denis Y., and Penney C.L. Synthesis and activity of 6-substituted purine linker amino acid immunostimulants. J. Med. Chem. 40 (1997) 2883-2894
-
(1997)
J. Med. Chem.
, vol.40
, pp. 2883-2894
-
-
Zacharie, B.1
Gagnon, L.2
Attardo, G.3
Connolly, T.P.4
St-Denis, Y.5
Penney, C.L.6
-
24
-
-
0034286962
-
Synergistic anti-tumor activity of a novel immunomodulator, BCH-1393, in combination with cyclophosphamide
-
Kadhim S., Penney C., Lagraoui M., Heibein J., Attardo G., Zacharie B., Connolly T., and Gagnon L. Synergistic anti-tumor activity of a novel immunomodulator, BCH-1393, in combination with cyclophosphamide. Int. J. Immunopharmacol. 22 (2000) 659-671
-
(2000)
Int. J. Immunopharmacol.
, vol.22
, pp. 659-671
-
-
Kadhim, S.1
Penney, C.2
Lagraoui, M.3
Heibein, J.4
Attardo, G.5
Zacharie, B.6
Connolly, T.7
Gagnon, L.8
-
25
-
-
0031934654
-
Expression of fos and jun genes in human skeletal muscle after exercise
-
Puntschart A., Wey E., Jostarndt K., Vogt M., Wittwer M., Widmer H.R., Hoppeler H., and Billeter R. Expression of fos and jun genes in human skeletal muscle after exercise. Am. J. Physiol.: Cell Physiol. 274 (1998) 129-137
-
(1998)
Am. J. Physiol.: Cell Physiol.
, vol.274
, pp. 129-137
-
-
Puntschart, A.1
Wey, E.2
Jostarndt, K.3
Vogt, M.4
Wittwer, M.5
Widmer, H.R.6
Hoppeler, H.7
Billeter, R.8
-
26
-
-
1842581764
-
Active protein kinase B regulates TCR responsiveness by modulating cytoplasmic-nuclear localization of NFAT and NF-kappa B proteins
-
Patra A.K., Na S.Y., and Bommhardt U. Active protein kinase B regulates TCR responsiveness by modulating cytoplasmic-nuclear localization of NFAT and NF-kappa B proteins. J. Immunol. 172 (2004) 4812-4820
-
(2004)
J. Immunol.
, vol.172
, pp. 4812-4820
-
-
Patra, A.K.1
Na, S.Y.2
Bommhardt, U.3
-
27
-
-
4744357460
-
Overview of interleukin-2 function, production and clinical applications
-
Gaffen S.L., and Liu K.D. Overview of interleukin-2 function, production and clinical applications. Cytokine 28 (2004) 109-123
-
(2004)
Cytokine
, vol.28
, pp. 109-123
-
-
Gaffen, S.L.1
Liu, K.D.2
-
28
-
-
0027943883
-
Induction by concanavalin A of specific mRNAs and cytolytic function in a CD8-positive T cell hybridoma
-
Gu J.J., Harriss J.V., Ozato K., and Gottlieb P.D. Induction by concanavalin A of specific mRNAs and cytolytic function in a CD8-positive T cell hybridoma. J. Immunol. 153 (1994) 4408-4417
-
(1994)
J. Immunol.
, vol.153
, pp. 4408-4417
-
-
Gu, J.J.1
Harriss, J.V.2
Ozato, K.3
Gottlieb, P.D.4
-
29
-
-
0026527505
-
Analysis of the AP-1 sites in the IL-2 promoter
-
Jain J., Valge-Archer V.E., and Rao A. Analysis of the AP-1 sites in the IL-2 promoter. J. Immunol. 148 (1992) 1240-1250
-
(1992)
J. Immunol.
, vol.148
, pp. 1240-1250
-
-
Jain, J.1
Valge-Archer, V.E.2
Rao, A.3
-
30
-
-
0019230964
-
T-cell growth factor
-
Smith K.A. T-cell growth factor. Immunol. Rev. 51 (1980) 337-357
-
(1980)
Immunol. Rev.
, vol.51
, pp. 337-357
-
-
Smith, K.A.1
-
31
-
-
18044394182
-
Interferons (IFNs) are key cytokines in both innate and adaptive antiviral immune responses- and viruses counteract IFN action
-
Bonjardim C.A. Interferons (IFNs) are key cytokines in both innate and adaptive antiviral immune responses- and viruses counteract IFN action. Microbes Infect. 7 (2005) 569-578
-
(2005)
Microbes Infect.
, vol.7
, pp. 569-578
-
-
Bonjardim, C.A.1
-
33
-
-
0021245601
-
The role of T3 surface molecules in the activation of human T cells: a two-stimulus requirement for IL 2 production reflects events occurring at a pre-translational level
-
Weiss A., Wiskocil R.L., and Stobo J.D. The role of T3 surface molecules in the activation of human T cells: a two-stimulus requirement for IL 2 production reflects events occurring at a pre-translational level. J. Immunol. 133 (1984) 123-128
-
(1984)
J. Immunol.
, vol.133
, pp. 123-128
-
-
Weiss, A.1
Wiskocil, R.L.2
Stobo, J.D.3
-
35
-
-
0036183618
-
Regulation of nuclear gamma interferon gene expression by interleukin 12 (IL-12) and IL-2 represents a novel form of posttranscriptional control
-
Hodge D.L., Martinez A., Julias J.G., Taylor L.S., and Young H.A. Regulation of nuclear gamma interferon gene expression by interleukin 12 (IL-12) and IL-2 represents a novel form of posttranscriptional control. Mol. Cell. Biol. 22 (2002) 1742-1753
-
(2002)
Mol. Cell. Biol.
, vol.22
, pp. 1742-1753
-
-
Hodge, D.L.1
Martinez, A.2
Julias, J.G.3
Taylor, L.S.4
Young, H.A.5
-
36
-
-
0032520908
-
Ultra low dose interleukin-2 therapy promotes a type 1 cytokine profile in vivo in patients with AIDS and AIDS-associated malignancies
-
Khatri V.P., Fehniger T.A., Baiocchi R.A., Yu F., Shah M.H., Schiller D.S., Gould M., Gazzinelli R.T., Bernstein Z.P., and Caligiuri M.A. Ultra low dose interleukin-2 therapy promotes a type 1 cytokine profile in vivo in patients with AIDS and AIDS-associated malignancies. J. Clin. Invest. 101 (1998) 1373-1378
-
(1998)
J. Clin. Invest.
, vol.101
, pp. 1373-1378
-
-
Khatri, V.P.1
Fehniger, T.A.2
Baiocchi, R.A.3
Yu, F.4
Shah, M.H.5
Schiller, D.S.6
Gould, M.7
Gazzinelli, R.T.8
Bernstein, Z.P.9
Caligiuri, M.A.10
-
37
-
-
0031020168
-
Upregulation of c-Fos in activated T lymphoid and monocytic cells by human immunodeficiency virus-1 Tat protein
-
Gibellini D., Caputo A., Capitani S., La Placa M., and Zauli G. Upregulation of c-Fos in activated T lymphoid and monocytic cells by human immunodeficiency virus-1 Tat protein. Blood 89 (1997) 1654-1664
-
(1997)
Blood
, vol.89
, pp. 1654-1664
-
-
Gibellini, D.1
Caputo, A.2
Capitani, S.3
La Placa, M.4
Zauli, G.5
-
38
-
-
0035103278
-
Extracellular Tat activates c-fos promoter in low serum-starved CD4+ T cells
-
Gibellini D., Re M.C., Ponti C., Celeghini C., Melloni E., La Placa M., and Zauli G. Extracellular Tat activates c-fos promoter in low serum-starved CD4+ T cells. Br. J. Haematol. 112 (2001) 663-670
-
(2001)
Br. J. Haematol.
, vol.112
, pp. 663-670
-
-
Gibellini, D.1
Re, M.C.2
Ponti, C.3
Celeghini, C.4
Melloni, E.5
La Placa, M.6
Zauli, G.7
-
39
-
-
0016736917
-
Adenosine inhibition of lymphocyte-mediated cytolysis: possible role of cyclic adenosine monophosphate
-
Wolberg G., Zimmerman T.P., Hiemstra K., Winston M., and Chu L.C. Adenosine inhibition of lymphocyte-mediated cytolysis: possible role of cyclic adenosine monophosphate. Science 187 (1975) 957-959
-
(1975)
Science
, vol.187
, pp. 957-959
-
-
Wolberg, G.1
Zimmerman, T.P.2
Hiemstra, K.3
Winston, M.4
Chu, L.C.5
-
40
-
-
0029066270
-
Adenosine acts as an endogenous modulator of IL-2-dependent proliferation of cytotoxic T lymphocytes
-
Antonysamy M.A., Moticka E.J., and Ramkumar V. Adenosine acts as an endogenous modulator of IL-2-dependent proliferation of cytotoxic T lymphocytes. J. Immunol. 155 (1995) 2813-2821
-
(1995)
J. Immunol.
, vol.155
, pp. 2813-2821
-
-
Antonysamy, M.A.1
Moticka, E.J.2
Ramkumar, V.3
-
41
-
-
0030878807
-
Role of A2a extracellular adenosine receptor-mediated signaling in adenosine-mediated inhibition of T-cell activation and expansion
-
Huang S., Apasov S., Koshiba M., and Sitkovsky M. Role of A2a extracellular adenosine receptor-mediated signaling in adenosine-mediated inhibition of T-cell activation and expansion. Blood 90 (1997) 1600-1610
-
(1997)
Blood
, vol.90
, pp. 1600-1610
-
-
Huang, S.1
Apasov, S.2
Koshiba, M.3
Sitkovsky, M.4
-
42
-
-
0033043321
-
Expression of A2B adenosine receptors in human lymphocytes: their role in T cell activation
-
Mirabet M., Herrera C., Cordero O.J., Mallol J., Lluis C., and Franco R. Expression of A2B adenosine receptors in human lymphocytes: their role in T cell activation. J. Cell. Sci. 112 Pt. 4 (1999) 491-502
-
(1999)
J. Cell. Sci.
, vol.112
, Issue.PART 4
, pp. 491-502
-
-
Mirabet, M.1
Herrera, C.2
Cordero, O.J.3
Mallol, J.4
Lluis, C.5
Franco, R.6
-
43
-
-
20444373378
-
Activation of Th1 and Tc1 cell adenosine A2A receptors directly inhibits IL-2 secretion in vitro and IL-2-driven expansion in vivo
-
Erdmann A.A., Gao Z.G., Jung U., Foley J., Borenstein T., Jacobson K.A., and Fowler D.H. Activation of Th1 and Tc1 cell adenosine A2A receptors directly inhibits IL-2 secretion in vitro and IL-2-driven expansion in vivo. Blood 105 (2005) 4707-4714
-
(2005)
Blood
, vol.105
, pp. 4707-4714
-
-
Erdmann, A.A.1
Gao, Z.G.2
Jung, U.3
Foley, J.4
Borenstein, T.5
Jacobson, K.A.6
Fowler, D.H.7
-
44
-
-
0023938335
-
The adenylate cyclase-cAMP-protein kinase A pathway and regulation of the immune response
-
Kammer G.M. The adenylate cyclase-cAMP-protein kinase A pathway and regulation of the immune response. Immunol. Today 9 (1988) 222-229
-
(1988)
Immunol. Today
, vol.9
, pp. 222-229
-
-
Kammer, G.M.1
-
45
-
-
0033524977
-
CD3- and CD28-dependent induction of PDE7 required for T cell activation
-
Li L., Yee C., and Beavo J.A. CD3- and CD28-dependent induction of PDE7 required for T cell activation. Science 283 (1999) 848-851
-
(1999)
Science
, vol.283
, pp. 848-851
-
-
Li, L.1
Yee, C.2
Beavo, J.A.3
-
46
-
-
6344233216
-
TCR- and CD28-mediated recruitment of phosphodiesterase 4 to lipid rafts potentiates TCR signaling
-
Abrahamsen H., Baillie G., Ngai J., Vang T., Nika K., Ruppelt A., Mustelin T., Zaccolo M., Houslay M., and Tasken K. TCR- and CD28-mediated recruitment of phosphodiesterase 4 to lipid rafts potentiates TCR signaling. J. Immunol. 173 (2004) 4847-4858
-
(2004)
J. Immunol.
, vol.173
, pp. 4847-4858
-
-
Abrahamsen, H.1
Baillie, G.2
Ngai, J.3
Vang, T.4
Nika, K.5
Ruppelt, A.6
Mustelin, T.7
Zaccolo, M.8
Houslay, M.9
Tasken, K.10
-
47
-
-
0035910759
-
Activation of the COOH-terminal Src kinase (Csk) by cAMP-dependent protein kinase inhibits signaling through the T cell receptor
-
Vang T., Torgersen K.M., Sundvold V., Saxena M., Levy F.O., Skalhegg B.S., Hansson V., Mustelin T., and Tasken K. Activation of the COOH-terminal Src kinase (Csk) by cAMP-dependent protein kinase inhibits signaling through the T cell receptor. J. Exp. Med. 193 (2001) 497-507
-
(2001)
J. Exp. Med.
, vol.193
, pp. 497-507
-
-
Vang, T.1
Torgersen, K.M.2
Sundvold, V.3
Saxena, M.4
Levy, F.O.5
Skalhegg, B.S.6
Hansson, V.7
Mustelin, T.8
Tasken, K.9
-
48
-
-
0026411104
-
Cyclophosphamide toxicity. Characterising and avoiding the problem
-
Fraiser L.H., Kanekal S., and Kehrer J.P. Cyclophosphamide toxicity. Characterising and avoiding the problem. Drugs 42 (1991) 781-795
-
(1991)
Drugs
, vol.42
, pp. 781-795
-
-
Fraiser, L.H.1
Kanekal, S.2
Kehrer, J.P.3
|