-
1
-
-
20244372077
-
Therapeutic strategies for rheumatoid arthritis
-
O'Dell J.R. Therapeutic strategies for rheumatoid arthritis. N Engl J Med 350 (2004) 2591-2602
-
(2004)
N Engl J Med
, vol.350
, pp. 2591-2602
-
-
O'Dell, J.R.1
-
3
-
-
3442875303
-
Pathogenesis of bone and cartilage destruction in rheumatoid arthritis
-
Goldring S.R. Pathogenesis of bone and cartilage destruction in rheumatoid arthritis. Rheumatology (Oxford) 42 Suppl. 2 (2003) ii11-ii16
-
(2003)
Rheumatology (Oxford)
, vol.42
, Issue.SUPPL. 2
-
-
Goldring, S.R.1
-
5
-
-
0038131975
-
Therapeutic strategies for rheumatoid arthritis
-
Smolen J.S., and Steiner G. Therapeutic strategies for rheumatoid arthritis. Nat Rev Drug Discov 2 (2003) 473-488
-
(2003)
Nat Rev Drug Discov
, vol.2
, pp. 473-488
-
-
Smolen, J.S.1
Steiner, G.2
-
6
-
-
0029617952
-
Modulation of proinflammatory cytokine release in rheumatoid synovial membrane cell cultures. Comparison of monoclonal anti TNF-alpha antibody with the interleukin-1 receptor antagonist
-
Butler D.M., Maini R.N., Feldmann M., and Brennan F.M. Modulation of proinflammatory cytokine release in rheumatoid synovial membrane cell cultures. Comparison of monoclonal anti TNF-alpha antibody with the interleukin-1 receptor antagonist. Eur Cytokine Netw 6 (1995) 225-230
-
(1995)
Eur Cytokine Netw
, vol.6
, pp. 225-230
-
-
Butler, D.M.1
Maini, R.N.2
Feldmann, M.3
Brennan, F.M.4
-
7
-
-
0037768899
-
The therapeutic potential of TNF-alpha blockade in rheumatoid arthritis
-
Paleolog E. The therapeutic potential of TNF-alpha blockade in rheumatoid arthritis. Expert Opin Investig Drugs 12 (2003) 1087-1095
-
(2003)
Expert Opin Investig Drugs
, vol.12
, pp. 1087-1095
-
-
Paleolog, E.1
-
8
-
-
2442590862
-
New drugs for rheumatoid arthritis
-
Olsen N.J., and Stein C.M. New drugs for rheumatoid arthritis. N Engl J Med 350 (2004) 2167-2179
-
(2004)
N Engl J Med
, vol.350
, pp. 2167-2179
-
-
Olsen, N.J.1
Stein, C.M.2
-
9
-
-
0034735842
-
Infliximab and methotrexate in the treatment of rheumatoid arthritis: anti-tumor necrosis factor trial in rheumatoid arthritis with concomitant therapy study group
-
Lipsky P.E., van der Heijde D.M., St. Clair E.W., Furst D.E., Breedveld F.C., Kalden J.R., et al. Infliximab and methotrexate in the treatment of rheumatoid arthritis: anti-tumor necrosis factor trial in rheumatoid arthritis with concomitant therapy study group. N Engl J Med 343 (2000) 1594-1602
-
(2000)
N Engl J Med
, vol.343
, pp. 1594-1602
-
-
Lipsky, P.E.1
van der Heijde, D.M.2
St. Clair, E.W.3
Furst, D.E.4
Breedveld, F.C.5
Kalden, J.R.6
-
10
-
-
20444478285
-
Suppressive effect of AIF, a water extract from three herbs, on collagen-induced arthritis in mice
-
Chang S.H., Sung H.C., Choi Y., Ko S.Y., Lee B.E., Baek D.H., et al. Suppressive effect of AIF, a water extract from three herbs, on collagen-induced arthritis in mice. Int Immunopharmacol 5 (2005) 1365-1372
-
(2005)
Int Immunopharmacol
, vol.5
, pp. 1365-1372
-
-
Chang, S.H.1
Sung, H.C.2
Choi, Y.3
Ko, S.Y.4
Lee, B.E.5
Baek, D.H.6
-
11
-
-
0018830639
-
Immunization against heterologous type II collagen induces arthritis in mice
-
Courtenay J.S., Dallman M.J., Dayan A.D., Martin A., and Mosedale B. Immunization against heterologous type II collagen induces arthritis in mice. Nature 283 (1980) 666-668
-
(1980)
Nature
, vol.283
, pp. 666-668
-
-
Courtenay, J.S.1
Dallman, M.J.2
Dayan, A.D.3
Martin, A.4
Mosedale, B.5
-
12
-
-
0036201483
-
Hypo-active variant of IL-2 and associated decreased T cell activation contribute to impaired apoptosis in autoimmune prone MRL mice
-
Choi Y., Simon-Stoos K., and Puck J.M. Hypo-active variant of IL-2 and associated decreased T cell activation contribute to impaired apoptosis in autoimmune prone MRL mice. Eur J Immunol 32 (2002) 677-685
-
(2002)
Eur J Immunol
, vol.32
, pp. 677-685
-
-
Choi, Y.1
Simon-Stoos, K.2
Puck, J.M.3
-
13
-
-
33747830880
-
Towards a pro-inflammatory and immunomodulatory emerging role of leptin
-
Otero M., Lago R., Gomez R., Dieguez C., Lago F., Gomez-Reino J., et al. Towards a pro-inflammatory and immunomodulatory emerging role of leptin. Rheumatology (Oxford) 45 (2006) 944-950
-
(2006)
Rheumatology (Oxford)
, vol.45
, pp. 944-950
-
-
Otero, M.1
Lago, R.2
Gomez, R.3
Dieguez, C.4
Lago, F.5
Gomez-Reino, J.6
-
14
-
-
33645733084
-
Protective effect of vasoactive intestinal peptide on bone destruction in the collagen-induced arthritis model of rheumatoid arthritis
-
Juarranz Y., Abad C., Martinez C., Arranz A., Gutierrez-Canas I., Rosignoli F., et al. Protective effect of vasoactive intestinal peptide on bone destruction in the collagen-induced arthritis model of rheumatoid arthritis. Arthritis Res Ther 7 (2005) R1034-R1045
-
(2005)
Arthritis Res Ther
, vol.7
-
-
Juarranz, Y.1
Abad, C.2
Martinez, C.3
Arranz, A.4
Gutierrez-Canas, I.5
Rosignoli, F.6
-
15
-
-
0030032444
-
Cloning, expression, and type II collagenolytic activity of matrix metalloproteinase-13 from human osteoarthritic cartilage
-
Mitchell P.G., Magna H.A., Reeves L.M., Lopresti-Morrow L.L., Yocum S.A., Rosner P.J., et al. Cloning, expression, and type II collagenolytic activity of matrix metalloproteinase-13 from human osteoarthritic cartilage. J Clin Invest 97 (1996) 761-768
-
(1996)
J Clin Invest
, vol.97
, pp. 761-768
-
-
Mitchell, P.G.1
Magna, H.A.2
Reeves, L.M.3
Lopresti-Morrow, L.L.4
Yocum, S.A.5
Rosner, P.J.6
-
16
-
-
16644372986
-
Endotoxin recognition and signal transduction by the TLR4/MD2-complex
-
Fitzgerald K.A., Rowe D.C., and Golenbock D.T. Endotoxin recognition and signal transduction by the TLR4/MD2-complex. Microbes Infect 6 (2004) 1361-1367
-
(2004)
Microbes Infect
, vol.6
, pp. 1361-1367
-
-
Fitzgerald, K.A.1
Rowe, D.C.2
Golenbock, D.T.3
-
17
-
-
0034190272
-
Activator protein 1 (AP-1)- and nuclear factor kappaB (NF-kappaB)-dependent transcriptional events in carcinogenesis
-
Hsu T.C., Young M.R., Cmarik J., and Colburn N.H. Activator protein 1 (AP-1)- and nuclear factor kappaB (NF-kappaB)-dependent transcriptional events in carcinogenesis. Free Radic Biol Med 28 (2000) 1338-1348
-
(2000)
Free Radic Biol Med
, vol.28
, pp. 1338-1348
-
-
Hsu, T.C.1
Young, M.R.2
Cmarik, J.3
Colburn, N.H.4
-
18
-
-
0033758633
-
Activation, differential localization, and regulation of the stress-activated protein kinases, extracellular signal-regulated kinase, c-JUN N-terminal kinase, and p38 mitogen-activated protein kinase, in synovial tissue and cells in rheumatoid arthritis
-
Schett G., Tohidast-Akrad M., Smolen J.S., Schmid B.J., Steiner C.W., Bitzan P., et al. Activation, differential localization, and regulation of the stress-activated protein kinases, extracellular signal-regulated kinase, c-JUN N-terminal kinase, and p38 mitogen-activated protein kinase, in synovial tissue and cells in rheumatoid arthritis. Arthritis Rheum 43 (2000) 2501-2512
-
(2000)
Arthritis Rheum
, vol.43
, pp. 2501-2512
-
-
Schett, G.1
Tohidast-Akrad, M.2
Smolen, J.S.3
Schmid, B.J.4
Steiner, C.W.5
Bitzan, P.6
-
19
-
-
0035865090
-
NF-kappa B regulation by I kappa B kinase-2 in rheumatoid arthritis synoviocytes
-
Aupperle K., Bennett B., Han Z., Boyle D., Manning A., and Firestein G. NF-kappa B regulation by I kappa B kinase-2 in rheumatoid arthritis synoviocytes. J Immunol 166 (2001) 2705-2711
-
(2001)
J Immunol
, vol.166
, pp. 2705-2711
-
-
Aupperle, K.1
Bennett, B.2
Han, Z.3
Boyle, D.4
Manning, A.5
Firestein, G.6
-
20
-
-
0034892866
-
Inhibitor of nuclear factor kappaB kinase beta is a key regulator of synovial inflammation
-
Tak P.P., Gerlag D.M., Aupperle K.R., van de Geest D.A., Overbeek M., Bennett B.L., et al. Inhibitor of nuclear factor kappaB kinase beta is a key regulator of synovial inflammation. Arthritis Rheum 44 (2001) 1897-1907
-
(2001)
Arthritis Rheum
, vol.44
, pp. 1897-1907
-
-
Tak, P.P.1
Gerlag, D.M.2
Aupperle, K.R.3
van de Geest, D.A.4
Overbeek, M.5
Bennett, B.L.6
-
21
-
-
67651142330
-
The proinflammatory cytokines IL-1beta and TNF-alpha induce the expression of synoviolin, an E3 ubiquitin ligase, in mouse synovial fibroblasts via the Erk1/2-ETS1 pathway
-
Gao B., Calhoun K., and Fang D. The proinflammatory cytokines IL-1beta and TNF-alpha induce the expression of synoviolin, an E3 ubiquitin ligase, in mouse synovial fibroblasts via the Erk1/2-ETS1 pathway. Arthritis Res Ther 8 (2006) R172
-
(2006)
Arthritis Res Ther
, vol.8
-
-
Gao, B.1
Calhoun, K.2
Fang, D.3
-
22
-
-
0034931503
-
c-Jun N-terminal kinase is required for metalloproteinase expression and joint destruction in inflammatory arthritis
-
Han Z., Boyle D.L., Chang L., Bennett B., Karin M., Yang L., et al. c-Jun N-terminal kinase is required for metalloproteinase expression and joint destruction in inflammatory arthritis. J Clin Invest 108 (2001) 73-81
-
(2001)
J Clin Invest
, vol.108
, pp. 73-81
-
-
Han, Z.1
Boyle, D.L.2
Chang, L.3
Bennett, B.4
Karin, M.5
Yang, L.6
-
23
-
-
9144251043
-
A novel mechanism for TNF-alpha regulation by p38 MAPK: involvement of NF-kappa B with implications for therapy in rheumatoid arthritis
-
Campbell J., Ciesielski C.J., Hunt A.E., Horwood N.J., Beech J.T., Hayes L.A., et al. A novel mechanism for TNF-alpha regulation by p38 MAPK: involvement of NF-kappa B with implications for therapy in rheumatoid arthritis. J Immunol 173 (2004) 6928-6937
-
(2004)
J Immunol
, vol.173
, pp. 6928-6937
-
-
Campbell, J.1
Ciesielski, C.J.2
Hunt, A.E.3
Horwood, N.J.4
Beech, J.T.5
Hayes, L.A.6
-
24
-
-
36148940515
-
-
Scizhen L. Bone Cho Kang Mook [Compendium of material medica] 1978 [1590 A.D.].
-
-
-
-
25
-
-
0032968241
-
Anti-inflammatory effects of total saponins of Panax notoginseng
-
Li S.H., and Chu Y. Anti-inflammatory effects of total saponins of Panax notoginseng. Zhongguo Yao Li Xue Bao 20 (1999) 551-554
-
(1999)
Zhongguo Yao Li Xue Bao
, vol.20
, pp. 551-554
-
-
Li, S.H.1
Chu, Y.2
-
26
-
-
13444262239
-
A Korean herbal medicine, Panax notoginseng, prevents liver fibrosis and hepatic microvascular dysfunction in rats
-
Park W.H., Lee S.K., and Kim C.H. A Korean herbal medicine, Panax notoginseng, prevents liver fibrosis and hepatic microvascular dysfunction in rats. Life Sci 76 (2005) 1675-1690
-
(2005)
Life Sci
, vol.76
, pp. 1675-1690
-
-
Park, W.H.1
Lee, S.K.2
Kim, C.H.3
-
27
-
-
33646534388
-
Panax notoginseng attenuates LPS-induced pro-inflammatory mediators in RAW264.7 cells
-
Rhule A., Navarro S., Smith J.R., and Shepherd D.M. Panax notoginseng attenuates LPS-induced pro-inflammatory mediators in RAW264.7 cells. J Ethnopharmacol 106 (2006) 121-128
-
(2006)
J Ethnopharmacol
, vol.106
, pp. 121-128
-
-
Rhule, A.1
Navarro, S.2
Smith, J.R.3
Shepherd, D.M.4
-
28
-
-
33749125002
-
-
Wang Y, Peng D, Huang W, Zhou X, Liu J, Fang Y. Mechanism of altered TNF-alpha expression by macrophage and the modulatory effect of Panax notoginseng saponins in scald mice. Burns 2006;27 [Epub ahead of print].
-
-
-
-
29
-
-
0026303489
-
Separation and identification of main medicinal saponin components from mass cell cultures of Panax notoginseng (Burk) F. H. Chen
-
Zhou L.G., Zheng G.Z., Gan F.Y., Wang S.L., Yang C.R., and Xu C. Separation and identification of main medicinal saponin components from mass cell cultures of Panax notoginseng (Burk) F. H. Chen. Yao Xue Xue Bao 26 (1991) 876-880
-
(1991)
Yao Xue Xue Bao
, vol.26
, pp. 876-880
-
-
Zhou, L.G.1
Zheng, G.Z.2
Gan, F.Y.3
Wang, S.L.4
Yang, C.R.5
Xu, C.6
-
30
-
-
33646040652
-
Notoginsenoside R1 inhibits TNF-alpha-induced fibronectin production in smooth muscle cells via the ROS/ERK pathway
-
Zhang H.S., and Wang S.Q. Notoginsenoside R1 inhibits TNF-alpha-induced fibronectin production in smooth muscle cells via the ROS/ERK pathway. Free Radic Biol Med 40 (2006) 1664-1674
-
(2006)
Free Radic Biol Med
, vol.40
, pp. 1664-1674
-
-
Zhang, H.S.1
Wang, S.Q.2
-
31
-
-
33644791402
-
Notoginsenoside R1 from Panax notoginseng inhibits TNF-alpha-induced PAI-1 production in human aortic smooth muscle cells
-
Zhang H.S., and Wang S.Q. Notoginsenoside R1 from Panax notoginseng inhibits TNF-alpha-induced PAI-1 production in human aortic smooth muscle cells. Vascul Pharmacol 44 (2006) 224-230
-
(2006)
Vascul Pharmacol
, vol.44
, pp. 224-230
-
-
Zhang, H.S.1
Wang, S.Q.2
-
32
-
-
33646001775
-
Oral absorption of ginsenoside Rb1 using in vitro and in vivo models
-
Han M., Sha X., Wu Y., and Fang X. Oral absorption of ginsenoside Rb1 using in vitro and in vivo models. Planta Med 72 (2006) 398-404
-
(2006)
Planta Med
, vol.72
, pp. 398-404
-
-
Han, M.1
Sha, X.2
Wu, Y.3
Fang, X.4
-
33
-
-
33645214063
-
Difference in oral absorption of ginsenoside Rg1 between in vitro and in vivo models
-
Han M., and Fang X.L. Difference in oral absorption of ginsenoside Rg1 between in vitro and in vivo models. Acta Pharmacol Sin 27 (2006) 499-505
-
(2006)
Acta Pharmacol Sin
, vol.27
, pp. 499-505
-
-
Han, M.1
Fang, X.L.2
-
34
-
-
30744438329
-
Absorption profiles of sanchinoside R1 and ginsenoside Rg1 in the rat intestine
-
Liang F., and Hua J.X. Absorption profiles of sanchinoside R1 and ginsenoside Rg1 in the rat intestine. Eur J Drug Metab Pharmacokinet 30 (2005) 261-268
-
(2005)
Eur J Drug Metab Pharmacokinet
, vol.30
, pp. 261-268
-
-
Liang, F.1
Hua, J.X.2
-
35
-
-
0037296911
-
Pharmacokinetics and bioavailability of ginsenoside Rb1 and Rg1 from Panax notoginseng in rats
-
Xu Q.F., Fang X.L., and Chen D.F. Pharmacokinetics and bioavailability of ginsenoside Rb1 and Rg1 from Panax notoginseng in rats. J Ethnopharmacol 84 (2003) 187-192
-
(2003)
J Ethnopharmacol
, vol.84
, pp. 187-192
-
-
Xu, Q.F.1
Fang, X.L.2
Chen, D.F.3
|