-
1
-
-
0024370136
-
Estimates of the prevalence of selected arthritic and musculoskeletal diseases in the United States
-
LAWRENCE RC, HOCHBERG MC, KELSEY JL et al.: Estimates of the prevalence of selected arthritic and musculoskeletal diseases in the United States. J. Rheumatol. (1989) 16:427-441.
-
(1989)
J. Rheumatol.
, vol.16
, pp. 427-441
-
-
Lawrence, R.C.1
Hochberg, M.C.2
Kelsey, J.L.3
-
2
-
-
0022472753
-
Pathogenesis of rheumatoid arthritis
-
HARRIS ED Jr: Pathogenesis of rheumatoid arthritis. Am. J. Med. (1986) 80:4-10.
-
(1986)
Am. J. Med.
, vol.80
, pp. 4-10
-
-
Harris E.D., Jr.1
-
3
-
-
0037235944
-
Survival in rheumatoid arthritis: A population-based analysis of trends over 40 years
-
GABRIEL SE, CROWSON CS, KREMERS HM et al.: Survival in rheumatoid arthritis: a population-based analysis of trends over 40 years. Arthritis Rheum. (2003) 48:54-58.
-
(2003)
Arthritis Rheum.
, vol.48
, pp. 54-58
-
-
Gabriel, S.E.1
Crowson, C.S.2
Kremers, H.M.3
-
4
-
-
0036229685
-
Accelerated atherosclerosis: An extraarticular feature of rheumatoid arthritis?
-
VAN DOORNUM S, MCCOLL G, WICKS IP: Accelerated atherosclerosis: an extraarticular feature of rheumatoid arthritis? Arthritis Rheum. (2002) 46:862-873.
-
(2002)
Arthritis Rheum.
, vol.46
, pp. 862-873
-
-
Van Doornum, S.1
Mccoll, G.2
Wicks, I.P.3
-
5
-
-
0037432305
-
Cardiovascular morbidity and mortality in women diagnosed with rheumatoid arthritis
-
SOLOMON DH, KARISON EW, RIMM EB et al.: Cardiovascular morbidity and mortality in women diagnosed with rheumatoid arthritis. Circulation (2003) 107:1303-1307.
-
(2003)
Circulation
, vol.107
, pp. 1303-1307
-
-
Solomon, D.H.1
Karison, E.W.2
Rimm, E.B.3
-
6
-
-
0026667263
-
Arthritis. The cumulative impact of a common chronic condition
-
YELIN E: Arthritis. The cumulative impact of a common chronic condition. Arthritis Rheum. (1992) 35:489-497.
-
(1992)
Arthritis Rheum.
, vol.35
, pp. 489-497
-
-
Yelin, E.1
-
7
-
-
0035883897
-
Rheumatoid arthritis
-
LEE DM, WEINBLATT ME: Rheumatoid arthritis. Lancet (2001) 358:903-911.
-
(2001)
Lancet
, vol.358
, pp. 903-911
-
-
Lee, D.M.1
Weinblatt, M.E.2
-
8
-
-
0033552883
-
Atherosclerosis-an inflammatory disease
-
ROSS R: Atherosclerosis-an inflammatory disease. N. Engl. J. Med. (1999) 340:115-126.
-
(1999)
N. Engl. J. Med.
, vol.340
, pp. 115-126
-
-
Ross, R.1
-
9
-
-
0022552224
-
Human recombinant interleukin 1 stimulates collagenase and prostaglandin E2 production by human synovial cells
-
DAYER JM, DE ROCHEMONTEIX B, BURRUS B, DEMCZUK S, DINARELLO CA: Human recombinant interleukin 1 stimulates collagenase and prostaglandin E2 production by human synovial cells. J. Clin. Invest. (1986) 77:645-648.
-
(1986)
J. Clin. Invest.
, vol.77
, pp. 645-648
-
-
Dayer, J.M.1
De Rochemonteix, B.2
Burrus, B.3
Demczuk, S.4
Dinarello, C.A.5
-
10
-
-
0026033431
-
Constitutive production of inflammatory and mitogenic cytokines by rheumatoid synovial fibroblasts
-
BUCALA R, RITCHLIN C, WINCHESTER R, CERAMI A: Constitutive production of inflammatory and mitogenic cytokines by rheumatoid synovial fibroblasts. J. Exp. Med. (1991) 173:569-574.
-
(1991)
J. Exp. Med.
, vol.173
, pp. 569-574
-
-
Bucala, R.1
Ritchlin, C.2
Winchester, R.3
Cerami, A.4
-
12
-
-
0026091413
-
Localization of tumor necrosis factor alpha in synovial tissues and at the cartilage-pannus junction in patients with rheumatoid arthritis
-
CHU CQ, FIELD M, FELDMANN M, MAINI RN: Localization of tumor necrosis factor alpha in synovial tissues and at the cartilage-pannus junction in patients with rheumatoid arthritis. Arthritis Rheum. (1991) 34:1125-1132.
-
(1991)
Arthritis Rheum.
, vol.34
, pp. 1125-1132
-
-
Chu, C.Q.1
Field, M.2
Feldmann, M.3
Maini, R.N.4
-
13
-
-
0025274640
-
Cytokines and cytokine inhibitors or antagonists in rheumatoid arthritis
-
AREND WP, DAYER JM: Cytokines and cytokine inhibitors or antagonists in rheumatoid arthritis. Arthritis Rheum. (1990) 33:305-315.
-
(1990)
Arthritis Rheum.
, vol.33
, pp. 305-315
-
-
Arend, W.P.1
Dayer, J.M.2
-
14
-
-
0028861236
-
Inhibition of the production and effects of interleukin-1 and tumor necrosis factor alpha in rheumatoid arthritis
-
AREND WP, DAYER JM: Inhibition of the production and effects of interleukin-1 and tumor necrosis factor alpha in rheumatoid arthritis. Arthritis Rheum. (1995) 38:151-160.
-
(1995)
Arthritis Rheum.
, vol.38
, pp. 151-160
-
-
Arend, W.P.1
Dayer, J.M.2
-
15
-
-
0036584028
-
Development of anti-TNF therapy for rheumatoid arthritis
-
FELDMANN M: Development of anti-TNF therapy for rheumatoid arthritis. Nat. Rev. Immunol. (2002) 2:364-371.
-
(2002)
Nat. Rev. Immunol.
, vol.2
, pp. 364-371
-
-
Feldmann, M.1
-
17
-
-
0024678727
-
Cytokine production in culture by cells isolated from the synovial membrane
-
BRENNAN FM, CHANTRY D, JACKSON AM, MAINI RN, FELDMANN M: Cytokine production in culture by cells isolated from the synovial membrane. J. Autoimmun. (1989) 2(Suppl.):177-186.
-
(1989)
J. Autoimmun.
, vol.2
, Issue.SUPPL.
, pp. 177-186
-
-
Brennan, F.M.1
Chantry, D.2
Jackson, A.M.3
Maini, R.N.4
Feldmann, M.5
-
18
-
-
0026802287
-
Detection of cytokines at the cartilage/pannus junction in patients with rheumatoid arthritis: Implications for the role of cytokines in cartilage destruction and repair
-
CHU CQ, FIELD M, ALLARD S et al.: Detection of cytokines at the cartilage/pannus junction in patients with rheumatoid arthritis: implications for the role of cytokines in cartilage destruction and repair. Br. J. Rheumatol. (1992) 31:653-661.
-
(1992)
Br. J. Rheumatol.
, vol.31
, pp. 653-661
-
-
Chu, C.Q.1
Field, M.2
Allard, S.3
-
19
-
-
0026802524
-
Localization of tumor necrosis factor receptors in the synovial tissue and cartilage-pannus junction in patients with rheumatoid arthritis. Implications for local actions of tumor necrosis factor alpha
-
DELEURAN BW, CHU CQ, FIELD M et al.: Localization of tumor necrosis factor receptors in the synovial tissue and cartilage-pannus junction in patients with rheumatoid arthritis. Implications for local actions of tumor necrosis factor alpha. Arthritis Rheum. (1992) 35:1170-1178.
-
(1992)
Arthritis Rheum.
, vol.35
, pp. 1170-1178
-
-
Deleuran, B.W.1
Chu, C.Q.2
Field, M.3
-
20
-
-
0024314554
-
Inhibitory effect of TNF alpha antibodies on synovial cell interleukin-1 production in rheumatoid arthritis
-
(8657)
-
BRENNAN FM, CHANTRY D, JACKSON A, MAINI R, FELDMANN M: Inhibitory effect of TNF alpha antibodies on synovial cell interleukin-1 production in rheumatoid arthritis. Lancet (1989) 2(8657):244-247.
-
(1989)
Lancet
, vol.2
, pp. 244-247
-
-
Brennan, F.M.1
Chantry, D.2
Jackson, A.3
Maini, R.4
Feldmann, M.5
-
21
-
-
0029617952
-
Modulation of proinflammatory cytokine release in rheumatoid synovial membrane cell cultures. Comparison of monoclonal anti TNF-alpha antibody with the interleukin-1 receptor antagonist
-
BUTLER DM, MAINI RN, FELDMANN M, BRENNAN FM: Modulation of proinflammatory cytokine release in rheumatoid synovial membrane cell cultures. Comparison of monoclonal anti TNF-alpha antibody with the interleukin-1 receptor antagonist. Eur. Cytokine Netw. (1995) 6:225-230.
-
(1995)
Eur. Cytokine Netw.
, vol.6
, pp. 225-230
-
-
Butler, D.M.1
Maini, R.N.2
Feldmann, M.3
Brennan, F.M.4
-
22
-
-
0025939257
-
Expression of granulocyte-macrophage colony-stimulating factor in rheumatoid arthritis: Regulation by tumor necrosis factor-alpha
-
HAWORTH C, BRENNAN FM, CHANTRY D et al.: Expression of granulocyte-macrophage colony-stimulating factor in rheumatoid arthritis: regulation by tumor necrosis factor-alpha. Eur. J. Immunol. (1991) 21:2575-2579.
-
(1991)
Eur. J. Immunol.
, vol.21
, pp. 2575-2579
-
-
Haworth, C.1
Brennan, F.M.2
Chantry, D.3
-
23
-
-
0026644298
-
Anti-tumor necrosis factor ameliorates joint disease in murine collagen-induced arthritis
-
WILLIAMS RO, FELDMANN M, MAINI RN: Anti-tumor necrosis factor ameliorates joint disease in murine collagen-induced arthritis. Proc. Natl. Acad. Sci. USA (1992) 89:9784-9788.
-
(1992)
Proc. Natl. Acad. Sci. USA
, vol.89
, pp. 9784-9788
-
-
Williams, R.O.1
Feldmann, M.2
Maini, R.N.3
-
24
-
-
0026677361
-
Evolution of collagen arthritis in mice is arrested by treatment with anti-tumour necrosis factor (TNF) antibody or a recombinant soluble TNF receptor
-
PIGUET PF, GRAU GE, VESIN C et al.: Evolution of collagen arthritis in mice is arrested by treatment with anti-tumour necrosis factor (TNF) antibody or a recombinant soluble TNF receptor. Immunology (1992) 77:510-514.
-
(1992)
Immunology
, vol.77
, pp. 510-514
-
-
Piguet, P.F.1
Grau, G.E.2
Vesin, C.3
-
25
-
-
0026656850
-
Involvement of endogenous tumor necrosis factor alpha and transforming growth factor beta during induction of collagen Type II arthritis in mice
-
THORBECKE GJ, SHAH R, LEU CH et al.: Involvement of endogenous tumor necrosis factor alpha and transforming growth factor beta during induction of collagen Type II arthritis in mice. Proc. Natl. Acad. Sci. USA (1992) 89:7375-7379.
-
(1992)
Proc. Natl. Acad. Sci. USA
, vol.89
, pp. 7375-7379
-
-
Thorbecke, G.J.1
Shah, R.2
Leu, C.H.3
-
26
-
-
0027438710
-
Treatment of rheumatoid arthritis with chimeric monoclonal antibodies to tumor necrosis factor alpha
-
ELLIOTT MJ, MAINI RN, FELDMANN M et al.: Treatment of rheumatoid arthritis with chimeric monoclonal antibodies to tumor necrosis factor alpha. Arthritis Rheum. (1993) 36:1681-1690.
-
(1993)
Arthritis Rheum.
, vol.36
, pp. 1681-1690
-
-
Elliott, M.J.1
Maini, R.N.2
Feldmann, M.3
-
27
-
-
0028143211
-
Randomised double-blind comparison of chimeric monoclonal antibody to tumour necrosis factor alpha (cA2) versus placebo in rheumatoid arthritis
-
ELLIOTT MJ, MAINI RN, FELDMANN M et al.: Randomised double-blind comparison of chimeric monoclonal antibody to tumour necrosis factor alpha (cA2) versus placebo in rheumatoid arthritis. Lancet (1994) 344:1105-1110.
-
(1994)
Lancet
, vol.344
, pp. 1105-1110
-
-
Elliott, M.J.1
Maini, R.N.2
Feldmann, M.3
-
28
-
-
0031660364
-
Therapeutic efficacy of multiple intravenous infusions of anti-tumor necrosis factor alpha monoclonal antibody combined with low-dose weekly methotrexate in rheumatoid arthritis
-
MAINI RN, BREEDVELD FC, KALDEN JR et al.: Therapeutic efficacy of multiple intravenous infusions of anti-tumor necrosis factor alpha monoclonal antibody combined with low-dose weekly methotrexate in rheumatoid arthritis. Arthritis Rheum. (1998) 41:1552-1563.
-
(1998)
Arthritis Rheum.
, vol.41
, pp. 1552-1563
-
-
Maini, R.N.1
Breedveld, F.C.2
Kalden, J.R.3
-
29
-
-
0033524159
-
Infliximab (chimeric anti-tumour necrosis factor alpha monoclonal antibody) versus placebo in rheumatoid arthritis patients receiving concomitant methotrexate: A randomised Phase III trial
-
ATTRACT Study Group
-
MAINI R, ST CLAIR EW, BREEDVELD F et al.: Infliximab (chimeric anti-tumour necrosis factor alpha monoclonal antibody) versus placebo in rheumatoid arthritis patients receiving concomitant methotrexate: a randomised Phase III trial. ATTRACT Study Group. Lancet (1999) 354:1932-1939.
-
(1999)
Lancet
, vol.354
, pp. 1932-1939
-
-
Maini, R.1
St Clair, E.W.2
Breedveld, F.3
-
30
-
-
0033179534
-
Regulation of cytokines, cytokine inhibitors, and acute-phase proteins following anti-TNF-alpha therapy in rheumatoid arthritis
-
CHARLES P, ELLIOTT MJ, DAVIS D et al.: Regulation of cytokines, cytokine inhibitors, and acute-phase proteins following anti-TNF-alpha therapy in rheumatoid arthritis. J. Immunol. (1999) 163:1521-1528.
-
(1999)
J. Immunol.
, vol.163
, pp. 1521-1528
-
-
Charles, P.1
Elliott, M.J.2
Davis, D.3
-
31
-
-
0033758629
-
Systemic anti-tumor necrosis factor alpha therapy in rheumatoid arthritis down-regulates synovial tumor necrosis factor alpha synthesis
-
ULFGREN AK, ANDERSSON U, ENGSTROM M et al.: Systemic anti-tumor necrosis factor alpha therapy in rheumatoid arthritis down-regulates synovial tumor necrosis factor alpha synthesis. Arthritis Rheum. (2000) 43:2391-2396.
-
(2000)
Arthritis Rheum.
, vol.43
, pp. 2391-2396
-
-
Ulfgren, A.K.1
Andersson, U.2
Engstrom, M.3
-
32
-
-
0030013609
-
Deactivation of vascular endothelium by monoclonal anti-tumor necrosis factor alpha antibody in rheumatoid arthritis
-
PALEOLOG EM, HUNT M, ELLIOTT MJ et al.: Deactivation of vascular endothelium by monoclonal anti-tumor necrosis factor alpha antibody in rheumatoid arthritis. Arthritis Rheum. (1996) 39:1082-1091.
-
(1996)
Arthritis Rheum.
, vol.39
, pp. 1082-1091
-
-
Paleolog, E.M.1
Hunt, M.2
Elliott, M.J.3
-
33
-
-
0029896957
-
Decrease in cellularity and expression of adhesion molecules by anti-tumor necrosis factor alpha monoclonal antibody treatment in patients with rheumatoid arthritis
-
TAK PP, TAYLOR PC, BREEDVELD FC et al.: Decrease in cellularity and expression of adhesion molecules by anti-tumor necrosis factor alpha monoclonal antibody treatment in patients with rheumatoid arthritis. Arthritis Rheum. (1996) 39:1077-1081.
-
(1996)
Arthritis Rheum.
, vol.39
, pp. 1077-1081
-
-
Tak, P.P.1
Taylor, P.C.2
Breedveld, F.C.3
-
34
-
-
0343674489
-
Reduction of chemokine levels and leukocyte traffic to joints by tumor necrosis factor alpha blockade in patients with rheumatoid arthritis
-
TAYLOR PC, PETERS AM, PALEOLOG E et al.: Reduction of chemokine levels and leukocyte traffic to joints by tumor necrosis factor alpha blockade in patients with rheumatoid arthritis. Arthritis Rheum. (2000) 43:38-47.
-
(2000)
Arthritis Rheum.
, vol.43
, pp. 38-47
-
-
Taylor, P.C.1
Peters, A.M.2
Paleolog, E.3
-
35
-
-
0032705201
-
New vessels, new approaches: Angiogenesis as a therapeutic target in musculoskeletal disorders
-
BALLARA SC, MIOTLA JM, PALEOLOG EM: New vessels, new approaches: angiogenesis as a therapeutic target in musculoskeletal disorders. Int. J. Exp. Pathol. (1999) 80:235-250.
-
(1999)
Int. J. Exp. Pathol.
, vol.80
, pp. 235-250
-
-
Ballara, S.C.1
Miotla, J.M.2
Paleolog, E.M.3
-
36
-
-
34247568260
-
Angiogenesis in rheumatoid arthritis
-
PALEOLOG EM: Angiogenesis in rheumatoid arthritis. Arthritis Res. (2002) 4(Suppl. 3):S81-S90.
-
(2002)
Arthritis Res.
, vol.4
, Issue.SUPPL. 3
-
-
Paleolog, E.M.1
-
38
-
-
0028216495
-
Vascular permeability factor/endothelial growth factor (VPF/VEGF): Accumulation and expression in human synovial fluids and rheumatoid synovial tissue
-
FAVA RA, OLSEN NJ, SPENCER-GREEN G et al.: Vascular permeability factor/endothelial growth factor (VPF/VEGF): accumulation and expression in human synovial fluids and rheumatoid synovial tissue. J. Exp. Med. (1994) 180:341-346.
-
(1994)
J. Exp. Med.
, vol.180
, pp. 341-346
-
-
Fava, R.A.1
Olsen, N.J.2
Spencer-Green, G.3
-
39
-
-
0028199835
-
Vascular endothelial growth factor. A cytokine modulating endothelial function in rheumatoid arthritis
-
KOCH AE, HARLOW LA, HAINES GK et al.: Vascular endothelial growth factor. A cytokine modulating endothelial function in rheumatoid arthritis. J. Immunol. (1994) 152:4149-4156.
-
(1994)
J. Immunol.
, vol.152
, pp. 4149-4156
-
-
Koch, A.E.1
Harlow, L.A.2
Haines, G.K.3
-
40
-
-
0031810231
-
Modulation of angiogenic vascular endothelial growth factor (VEGF) by TNFα and IL-1 in rheumatoid arthritis
-
PALEOLOG EM, YOUNG S, STARK AC et al.: Modulation of angiogenic vascular endothelial growth factor (VEGF) by TNFα and IL-1 in rheumatoid arthritis. Arthritis Rheum. (1998) 41:1258-1265.
-
(1998)
Arthritis Rheum.
, vol.41
, pp. 1258-1265
-
-
Paleolog, E.M.1
Young, S.2
Stark, A.C.3
-
41
-
-
34247627779
-
VEGF and imaging of vessels in rheumatoid arthritis
-
TAYLOR PC: VEGF and imaging of vessels in rheumatoid arthritis. Arthritis Res. (2002) 4(Suppl. 3):S99-S107.
-
(2002)
Arthritis Res.
, vol.4
, Issue.SUPPL. 3
-
-
Taylor, P.C.1
-
42
-
-
0034735842
-
Infliximab and methotrexate in the treatment of rheumatoid arthritis
-
Anti-Tumor Necrosis Factor Trial in Rheumatoid Arthritis with Concomitant Therapy Study Group
-
LIPSKY PE, VAN DER HEIJDE DM, ST CLAIR EW et al.: Infliximab and methotrexate in the treatment of rheumatoid arthritis. Anti-Tumor Necrosis Factor Trial in Rheumatoid Arthritis with Concomitant Therapy Study Group. N. Engl. J. Med. (2000) 343:1594-1602.
-
(2000)
N. Engl. J. Med.
, vol.343
, pp. 1594-1602
-
-
Lipsky, P.E.1
Van Der Heijde, D.M.2
St Clair, E.W.3
-
43
-
-
0030640647
-
NMR monitoring of rheumatoid arthritis patients receiving anti-TNF-alpha monoclonal antibody therapy
-
KALDEN-NEMETH D, GREBMEIER J, ANTONI C et al.: NMR monitoring of rheumatoid arthritis patients receiving anti-TNF-alpha monoclonal antibody therapy. Rheumatol. Int. (1997) 16:249-255.
-
(1997)
Rheumatol. Int.
, vol.16
, pp. 249-255
-
-
Kalden-Nemeth, D.1
Grebmeier, J.2
Antoni, C.3
-
44
-
-
0030750272
-
Reduction of serum matrix metalloproteinase 1 and matrix metalloproteinase 3 in rheumatoid arthritis patients following anti-tumour necrosis factor-alpha (cA2) therapy
-
BRENNAN FM, BROWNE KA, GREEN PA et al.: Reduction of serum matrix metalloproteinase 1 and matrix metalloproteinase 3 in rheumatoid arthritis patients following anti-tumour necrosis factor-alpha (cA2) therapy. Br. J. Rheumatol. (1997) 36:643-650.
-
(1997)
Br. J. Rheumatol.
, vol.36
, pp. 643-650
-
-
Brennan, F.M.1
Browne, K.A.2
Green, P.A.3
-
45
-
-
0038047917
-
How does infliximab work in rheumatoid arthritis?
-
MAINI RN, FELDMANN M: How does infliximab work in rheumatoid arthritis? Arthritis Res. (2002) 4(Suppl. 2):S22-S28.
-
(2002)
Arthritis Res.
, vol.4
, Issue.SUPPL. 2
-
-
Maini, R.N.1
Feldmann, M.2
-
46
-
-
0036274944
-
Etanercept versus methotrexate in patients with early rheumatoid arthritis: Two-year radiographic and clinical outcomes
-
GENOVESE MC, BATHON JM, MARTIN RW et al.: Etanercept versus methotrexate in patients with early rheumatoid arthritis: two-year radiographic and clinical outcomes. Arthritis Rheum. (2002) 46:1443-1450.
-
(2002)
Arthritis Rheum.
, vol.46
, pp. 1443-1450
-
-
Genovese, M.C.1
Bathon, J.M.2
Martin, R.W.3
-
47
-
-
0037231533
-
Adalimumab, a fully human anti-tumor necrosis factor alpha monoclonal antibody, for the treatment of rheumatoid arthritis in patients taking concomitant methotrexate: The ARMADA trial
-
WEINBLATT ME, KEYSTONE EC, FURST DE et al.: Adalimumab, a fully human anti-tumor necrosis factor alpha monoclonal antibody, for the treatment of rheumatoid arthritis in patients taking concomitant methotrexate: the ARMADA trial. Arthritis Rheum. (2003) 48:35-45.
-
(2003)
Arthritis Rheum.
, vol.48
, pp. 35-45
-
-
Weinblatt, M.E.1
Keystone, E.C.2
Furst, D.E.3
-
48
-
-
0036899812
-
Therapeutic benefit of blocking interleukin-6 activity with an anti-interleukin-6 receptor monoclonal antibody in rheumatoid arthritis: A randomized, double-blind, placebo-controlled, dose-escalation trial
-
CHOY EH, ISENBERG DA, GARROOD T et al.: Therapeutic benefit of blocking interleukin-6 activity with an anti-interleukin-6 receptor monoclonal antibody in rheumatoid arthritis: a randomized, double-blind, placebo-controlled, dose-escalation trial. Arthritis Rheum. (2002) 46:3143-3150.
-
(2002)
Arthritis Rheum.
, vol.46
, pp. 3143-3150
-
-
Choy, E.H.1
Isenberg, D.A.2
Garrood, T.3
-
49
-
-
0036845130
-
Long-term safety and maintenance of clinical improvement following treatment with anakinra (recombinant human interleukin-1 receptor antagonist) in patients with rheumatoid arthritis: Extension phase of a randomized, double-blind, placebo-controlled trial
-
NUKI G, BRESNIHAN B, BEAR MB, MCCABE D: Long-term safety and maintenance of clinical improvement following treatment with anakinra (recombinant human interleukin-1 receptor antagonist) in patients with rheumatoid arthritis: extension phase of a randomized, double-blind, placebo-controlled trial. Arthritis Rheum. (2002) 46:2838-2846.
-
(2002)
Arthritis Rheum.
, vol.46
, pp. 2838-2846
-
-
Nuki, G.1
Bresnihan, B.2
Bear, M.B.3
Mccabe, D.4
-
50
-
-
0037389680
-
Anakinra, a recombinant human interleukin-1 receptor antagonist (r-metHuIL-1ra), in patients with rheumatoid arthritis: A large, international, multicenter, placebo-controlled trial
-
FLEISCHMANN RM, SCHECHTMAN J, BENNETT R et al.: Anakinra, a recombinant human interleukin-1 receptor antagonist (r-metHuIL-1ra), in patients with rheumatoid arthritis: A large, international, multicenter, placebo-controlled trial. Arthritis Rheum. (2003) 48:927-934.
-
(2003)
Arthritis Rheum.
, vol.48
, pp. 927-934
-
-
Fleischmann, R.M.1
Schechtman, J.2
Bennett, R.3
-
51
-
-
0029739255
-
A Phase I/II open label study of the safety and efficacy of an anti-ICAM-1 (intercellular adhesion molecule-1; CD54) monoclonal antibody in early rheumatoid arthritis
-
KAVANAUGH AF, DAVIS LS, JAIN RI et al.: A Phase I/II open label study of the safety and efficacy of an anti-ICAM-1 (intercellular adhesion molecule-1; CD54) monoclonal antibody in early rheumatoid arthritis. J. Rheumatol. (1996) 23:1338-1344.
-
(1996)
J. Rheumatol.
, vol.23
, pp. 1338-1344
-
-
Kavanaugh, A.F.1
Davis, L.S.2
Jain, R.I.3
-
52
-
-
0036796835
-
Repeat-cycle study of high-dose intravenous 4162W94 anti-CD4 humanized monoclonal antibody in rheumatoid arthritis. A randomized placebo-controlled trial
-
CHOY EH, PANAYI GS, EMERY P et al.: Repeat-cycle study of high-dose intravenous 4162W94 anti-CD4 humanized monoclonal antibody in rheumatoid arthritis. A randomized placebo-controlled trial. Rheumatology (Oxford) (2002) 41:1142-1148.
-
(2002)
Rheumatology (Oxford)
, vol.41
, pp. 1142-1148
-
-
Choy, E.H.1
Panayi, G.S.2
Emery, P.3
-
53
-
-
0026549481
-
Angiogenesis inhibition suppresses collagen arthritis
-
PEACOCK DJ, BANQUERIGO ML, BRAHN E: Angiogenesis inhibition suppresses collagen arthritis. J. Exp. Med. (1992) 175:1135-1138.
-
(1992)
J. Exp. Med.
, vol.175
, pp. 1135-1138
-
-
Peacock, D.J.1
Banquerigo, M.L.2
Brahn, E.3
-
54
-
-
0031921590
-
The effect of thalidomide and 2 analogs on collagen induced arthritis
-
OLIVER SJ, CHENG TP, BANQUERIGO ML, BRAHN E: The effect of thalidomide and 2 analogs on collagen induced arthritis. J. Rheumatol. (1998) 25:964-969.
-
(1998)
J. Rheumatol.
, vol.25
, pp. 964-969
-
-
Oliver, S.J.1
Cheng, T.P.2
Banquerigo, M.L.3
Brahn, E.4
-
55
-
-
0032893957
-
Decreased angiogenesis and arthritic disease in rabbits treated with an alphavbeta3 antagonist
-
STORGARD CM, STUPACK DG, JONCZYK A et al.: Decreased angiogenesis and arthritic disease in rabbits treated with an alphavbeta3 antagonist. J. Clin. Invest. (1999) 103:47-54.
-
(1999)
J. Clin. Invest.
, vol.103
, pp. 47-54
-
-
Storgard, C.M.1
Stupack, D.G.2
Jonczyk, A.3
-
56
-
-
0033888921
-
Treatment with soluble VEGF receptor reduces disease severity in murine collagen-induced arthritis
-
MIOTLA J, MACIEWICZ R, KENDREW J, FELDMANN M, PALEOLOG E: Treatment with soluble VEGF receptor reduces disease severity in murine collagen-induced arthritis. Lab. Invest. (2000) 80:1195-1205.
-
(2000)
Lab. Invest.
, vol.80
, pp. 1195-1205
-
-
Miotla, J.1
Maciewicz, R.2
Kendrew, J.3
Feldmann, M.4
Paleolog, E.5
-
57
-
-
0034114929
-
Vascular endothelial growth factor expression and regulation of murine collagen-induced arthritis
-
LU J, KASAMA T, KOBAYASHI K et al.: Vascular endothelial growth factor expression and regulation of murine collagen-induced arthritis. J. Immunol. (2000) 164:5922-5927.
-
(2000)
J. Immunol.
, vol.164
, pp. 5922-5927
-
-
Lu, J.1
Kasama, T.2
Kobayashi, K.3
-
58
-
-
0038248703
-
The angiogenesis inhibitor protease-activated kringles 1-5 reduces the severity of murine collagen-induced arthritis
-
SUMARIWALLA P, CAO Y, WU H, FELDMANN M, PALEOLOG E: The angiogenesis inhibitor protease-activated kringles 1-5 reduces the severity of murine collagen-induced arthritis. Arthritis Res. Ther (2003) 5:R32-R39.
-
(2003)
Arthritis Res. Ther.
, vol.5
-
-
Sumariwalla, P.1
Cao, Y.2
Wu, H.3
Feldmann, M.4
Paleolog, E.5
-
59
-
-
0035253586
-
Phase Ib trial of intravenous recombinant humanized monoclonal antibody to vascular endothelial growth factor in combination with chemotherapy in patients with advanced cancer: Pharmacologic and long-term safety data
-
MARGOLIN K, GORDON MS, HOLMGREN E et al.: Phase Ib trial of intravenous recombinant humanized monoclonal antibody to vascular endothelial growth factor in combination with chemotherapy in patients with advanced cancer: pharmacologic and long-term safety data. J Clin. Oncol. (2001) 19:851-856.
-
(2001)
J. Clin. Oncol.
, vol.19
, pp. 851-856
-
-
Margolin, K.1
Gordon, M.S.2
Holmgren, E.3
-
60
-
-
0342993407
-
Inhibitory effects of anti-rheumatic drugs on vascular endothelial growth factor in cultured rheumatoid synovial cells
-
NAGASHIMA M, YOSHINO S, AONO H, TAKAI M, SASANO M: Inhibitory effects of anti-rheumatic drugs on vascular endothelial growth factor in cultured rheumatoid synovial cells. Clin. Exp. Immunol. (1999) 116:360-365.
-
(1999)
Clin. Exp. Immunol.
, vol.116
, pp. 360-365
-
-
Nagashima, M.1
Yoshino, S.2
Aono, H.3
Takai, M.4
Sasano, M.5
-
61
-
-
0033709917
-
Effects of combinations of anti-rheumatic drugs on the production of vascular endothelial growth factor and basic fibroblast growth factor in cultured synoviocytes and patients with rheumatoid arthritis
-
NAGASHIMA M, WAUKE K, HIRANO D et al.: Effects of combinations of anti-rheumatic drugs on the production of vascular endothelial growth factor and basic fibroblast growth factor in cultured synoviocytes and patients with rheumatoid arthritis. Rheumatology (Oxford) (2000) 39:1255-1262.
-
(2000)
Rheumatology (Oxford)
, vol.39
, pp. 1255-1262
-
-
Nagashima, M.1
Wauke, K.2
Hirano, D.3
-
62
-
-
0036839571
-
Is NF-kappaB a useful therapeutic target in rheumatoid arthritis?
-
FELDMANN M, ANDREAKOS E, SMITH C et al.: Is NF-kappaB a useful therapeutic target in rheumatoid arthritis? Ann. Rheum. Dis. (2002) 61(Suppl. 2):II13-II18.
-
(2002)
Ann. Rheum. Dis.
, vol.61
, Issue.SUPPL. 2
-
-
Feldmann, M.1
Andreakos, E.2
Smith, C.3
-
63
-
-
0037442674
-
VEGF expression in human macrophages is NF-κB-dependent: Studies using adenoviruses expressing the endogenous NF-κB inhibitor IκBα and a kinase defective form of the IκB kinase 2
-
KIRIAKIDIS S, ANDREAKOS E, MONACO C et al.: VEGF expression in human macrophages is NF-κB-dependent: studies using adenoviruses expressing the endogenous NF-κB inhibitor IκBα and a kinase defective form of the IκB kinase 2. J. Cell Sci. (2003) 116:665-674.
-
(2003)
J. Cell Sci.
, vol.116
, pp. 665-674
-
-
Kiriakidis, S.1
Andreakos, E.2
Monaco, C.3
-
64
-
-
0038575364
-
Heterogeneous requirement of IκB kinase 2 for inflammatory cytokine and matrix metalloproteinase production in rheumatoid arthritis: Implications for therapy
-
(In press)
-
ANDREAKOS E, SMITH C, KIRIAKIDIS S et al.: Heterogeneous requirement of IκB kinase 2 for inflammatory cytokine and matrix metalloproteinase production in rheumatoid arthritis: implications for therapy. Arthritis Rheum. (2003) (In press).
-
(2003)
Arthritis Rheum.
-
-
Andreakos, E.1
Smith, C.2
Kiriakidis, S.3
-
65
-
-
0037289728
-
IκB kinase 2 but not NF-kappa B-inducing kinase is essential for effective DC antigen presentation in the allogeneic mixed lymphocyte reaction
-
ANDREAKOS E, SMITH C, MONACO C et al.: IκB kinase 2 but not NF-kappa B-inducing kinase is essential for effective DC antigen presentation in the allogeneic mixed lymphocyte reaction. Blood (2003) 101:983-991.
-
(2003)
Blood
, vol.101
, pp. 983-991
-
-
Andreakos, E.1
Smith, C.2
Monaco, C.3
-
66
-
-
0035875764
-
Effect of human recombinant vascular endothelial growth factor 165 on progression of atherosclerotic plaque
-
CELLETTI FL, HILFIKER PR, GHAFOURI P, DAKE MD: Effect of human recombinant vascular endothelial growth factor 165 on progression of atherosclerotic plaque. J. Am. Coll. Cardiol. (2001) 37:2126-2130.
-
(2001)
J. Am. Coll. Cardiol.
, vol.37
, pp. 2126-2130
-
-
Celletti, F.L.1
Hilfiker, P.R.2
Ghafouri, P.3
Dake, M.D.4
-
67
-
-
0003055363
-
Reduced synovial vascularity following TNFα blockade in rheumatoid arthritis
-
TAYLOR P, PATEL S, PALEOLOG E et al.: Reduced synovial vascularity following TNFα blockade in rheumatoid arthritis. Arthritis Rheum. (1998) 41(Suppl. 9):S295.
-
(1998)
Arthritis Rheum.
, vol.41
, Issue.SUPPL. 9
-
-
Taylor, P.1
Patel, S.2
Paleolog, E.3
-
68
-
-
0030881463
-
Anaemia of chronic disease in rheumatoid arthritis: In vivo effects of tumour necrosis factor alpha blockade
-
DAVIS D, CHARLES PJ, POTTER A et al.: Anaemia of chronic disease in rheumatoid arthritis: in vivo effects of tumour necrosis factor alpha blockade. Br. J. Rheumatol. (1997) 36:950-956.
-
(1997)
Br. J. Rheumatol.
, vol.36
, pp. 950-956
-
-
Davis, D.1
Charles, P.J.2
Potter, A.3
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