Protective effect of diphenylmethyl selenocyanate against CCl 4-induced hepatic injury

Journal of Applied Toxicology

Volumn 27, Issue 6, 2007, Pages 527-537

  Das, Rajat Kumar ^a   Hossain, Sk Ugir ^a   Bhattacharya, Sudin ^a  

^a CHITTARANJAN NATIONAL CANCER INSTITUTE   (India)

Author keywords

Carbon tetrachloride (CCl4); CCl4 induced DNA damage; CCl4 induced liver apoptosis; CCl4 induced liver necrosis; Comet assay; Diphenylmethyl selenocyanate; Organoselenocyanates

Indexed keywords

CARBON TETRACHLORIDE; DIPHENYLMETHYL SELENOCYANATE; DNA; ORGANOSELENIUM DERIVATIVE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CONTROLLED STUDY; DNA DAMAGE; DRUG MECHANISM; DRUG SYNTHESIS; FEMALE; HEART MUSCLE CELL; IN VIVO STUDY; LIVER INJURY; LIVER NECROSIS; MOUSE; NONHUMAN; PRIORITY JOURNAL; THERAPY EFFECT;

ADMINISTRATION, ORAL; ANIMALS; ANTIOXIDANTS; APOPTOSIS; CARBON TETRACHLORIDE; COMET ASSAY; DISEASE MODELS, ANIMAL; DNA DAMAGE; FEMALE; LIVER; MASSIVE HEPATIC NECROSIS; MICE; ORGANOSELENIUM COMPOUNDS; OXIDATIVE STRESS; TIME FACTORS;

MUS;

EID: 36148932147     PISSN: 0260437X     EISSN: 10991263     Source Type: Journal    
DOI: 10.1002/jat.1230     Document Type: Article

References (48)

1. Atkinson JB, Hill KE, Burk RF. 2001. Centrilobular endothelial cell injury by diquat in the selenium-deficient rat liver. Lab. Invest. 81: 193-200.
2. 4-induced toxicity in isolated hepatocytes: the importance of direct solvent injury. Hepatology 6: 36-45.
3. 4 by cytochrome P450 and effects on lipid homeostasis. Z. Naturforsch. 56c: 111-121.
4. Boll M, Weber LWD, Becker E, Stampfl A. 2001b. Mechanism of carbon tetrachloride-induced hepatotoxicity. Hepatocellular damage by reactive carbon tetrachloride metabolites. Z. Naturforsch. 56c: 649-659.
5. Borges LP, Borges VC, Moro AV, Nogueira CW, Rocha JB, Zeni G. 2005. Protective effect of diphenyl diselenide on acute liver damage induced by 2-nitropropane in rats. Toxicology 210: 1-8.
6. Caderni G, De Filippo C, Luceri C, Salvadori M, Giannini A, Biggeri A, Remy S, Cheynier V, Dolara P. 2000. Effects of black tea, green tea and wine extracts on intestinal carcinogenesis induced by azoxymethane in F344 rats. Carcinogenesis 21: 1965-1969.
7. Collins AR, Duthie SJ, Dobson VL. 1993. Direct enzymic detection of endogenous oxidative base damage in human lymphocyte DNA. Carcinogenesis 14: 1733-1735.
8. Corcoran GB, Fix L, Jones DP, Moslen MT, Nicotera P, Oberhammer FA, Buttyan R. 1994. Contemporary issues in toxicology. Apoptosis: molecular control point in toxicity. Toxicol. Appl. Pharmacol. 128: 169-181.
9. Czaja MJ, Xu J, Alt E. 1995. Prevention of carbon tetrachloride-induced rat liver injury by soluble tumor necrosis factor receptor. Gastroenterology 108: 1849-1854.
10. Das RK, Bhattacharya S. 2004. Inhibition of DMBA-croton oil two-stage mouse skin carcinogenesis by diphenylmethyl selenocyanate through modulation of cutaneous oxidative stress and inhibition of nitric oxide production. Asian Pacific J. Cancer Prev. 5: 151-158.
11. Das RK, Bhattacharya S. 2005. Anti-tumour promoting activity of diphenylmethyl selenocyanate against two-stage mouse skin carcinogenesis. Asian Pacific J. Cancer Prev. 6: 181-188.
12. Das RK, Das S, Bhattacharya S. 2004a. Protective effect of diphenylmethyl selenocyanate against carbon tetrachloride induced hepatotoxicity in vivo. J. Environ. Path. Toxicol. Oncol. 23: 287-296.
13. Das RK, Ghosh S, Sengupta A, Bhattacharya S. 2004b. Inhibition of DMBA-croton oil induced two-stage mouse skin carcinogenesis by diphenylmethyl selenocyanate. Eur. J. Cancer Prev. 13: 411-417.
14. Das RK, Hossain Sk U, Bhattacharya S. 2005. Diphenylmethyl selenocyanate inhibits DMBA-croton oil induced two-stage mouse skin carcinogenesis by inducing apoptosis and inhibiting cutaneous cell proliferation. Cancer Lett. 230: 90-101.
15. DiRenzo AB, Gandolfi AJ, Sipes IG. 1982. Microsomal bioactivation and covalent binding of aliphatic halides to DNA. Toxicol. Lett. 11: 243-252.
16. Eastman A, Barry MA. 1992. The origins of DNA breaks: a consequence of DNA damage, DNA repair, or apoptosis? Cancer Invest. 10: 229-240.
17. 4-induced hepatic injury. J. Vet. Med. Sci. 64: 761-765.
18. Fairbairn DW, Walburger DK, Fairbairn JJ, O'Neill KL. 1996. Key morphologic changes and DNA strand breaks in human lymphoid cells: discriminating apoptosis from necrosis. Scanning 18: 407-416.
19. Ganther HE. 1987. Chemistry and metabolism of selenium. In Selenium in Biology and Medicine (Part A), Combs GF Jr, Spallholz JE, Levander OA, Oldfield JE (eds). AVI: Westport; 53-65.
20. Garcia MS. 2004. Organoselenium compounds as potential therapeutic and chemopreventive agents: a review. Curr. Med. Chem. 11: 1657-1669.
21. Ghosh S, Das RK, Sengupta A, Bhattacharya S. 2005a. Induction of apoptosis and inhibition of cell proliferation by diphenylmethyl selenocyanate during azoxymethane induced rat colon carcinogenesis. Int. J. Cancer Prev. 2: 63-70.
22. Ghosh S, Das RK, Sengupta A, Bhattacharya S. 2005b. Inhibition of azoxymethane-induced aberrant crypt foci in rat by diphenylmethyl selenocyanate through downregulation of COX-2 and modulation of glutathione-S-transferase and lipid peroxidation. Biol. Trac. Elem. Res. 105: 171-185.
23. Haouzi D, Lekehal M, Moreau A, Moulis C, Feldmann G, Robin MA, Lettéron P, Fau D, Pessayre D. 2000. Cytochrome P450-generated reactive metabolites cause mitochondrial permeability transition, caspase activation, and apoptosis in rat hepatocytes. Hepatology 32: 303-311.
24. Hartmann A, Agurell E, Beevers C, Brendler-Schwaab S, Burlinson B, Clay P, Collins A, Smith A, Speit G, Thybaud V, Tice RR. 2003. Recommendation for conducting the in vivo alkaline comet assay. Mutagenesis 18: 45-51.
25. Henderson L, Wolfreys A, Fedyk J, Bourner C, Windebank S. 1998. The ability of the comet assay to discriminate between genotoxins and cytotoxins. Mutagenesis 13: 89-94.
26. Hurná E, Siklenka P, Hurná S. 1997. Effect of selenium on cadmium genotoxicity investigated by micronucleus assay. Vet. Med. Czech. 42: 339-342.
27. Ianas O, Olinescu R, Badescu I, Simionescu L, Popovici D. 1995. The influence of 'selenium organicum' upon the hepatic function of carbon tetrachloride poisoned rats. Rom. J. Inter. Med. 33: 113-120.
28. Jialan S, Kenichi A, Yoji I, Kenjiro W. 1998. Evidence of hepatocyte apoptosis in rat liver after the administration of carbon tetrachloride. Am. J. Pathol. 153: 515-525.
29. Lindahl T, Andersson A. 1972. Rate of chain breakage at apurinic sites in double-stranded deoxyribonucleic acid. Biochemistry 11: 3618-3623.
30. Luckey SW, Petersen DR. 2001. Activation of Kupffer cells during the course of carbon tetrachloride-induced liver injury and fibrosis in rats. Exp. Mol. Pathol. 71: 226-240.
31. Meotti FC, Stangherlin EC, Zeni G, Nogueira CW, Rocha JBT. 2004. Protective role of aryl and alkyl diselenides on lipid peroxidation. Environ. Res. 94: 276-282.
32. Møller P, Wallin H. 1998. Adduct formation, mutagenesis and nucleotide excision repair of DNA damage produced by reactive oxygen species and lipid peroxidation product. Mutat. Res. 410: 271-290.
33. 3, and 1,1-dibromochloroethylene (vinylidene chloride). Biochem. Pharmacol. 29: 2505-2511.
34. Nogueira CW, Zeni G, Rocha JB. 2004. Organoselenium and organotellurium compounds: toxicology and pharmacology. Chem. Rev. 104: 6255-6286.
35. Olive PL, Frazer G, Banath JP. 1993. Radiation-induced apoptosis measured in TK6 human B lymphoblast cells using the comet assay. Radiat. Res. 136: 130-136.
36. Olivieri O, Girelli D, Stanzial AM, Rossi L, Bassi A, Corrocher R. 1996. Selenium, zinc, and thyroid hormones in healthy subjects: low T3/T4 ratio in the elderly is related to impaired selenium status. Biol. Trace Elem. Res. 51: 31-41.
37. Othman AAS, Khurshid A, Mahmoud NN, Ammar CAR, Abdullah MAB. 2000. Protective effect of aminoguanidene, a nitric oxide synthase inhibitor, against carbon tetrachloride induced hepatotoxicity in mice. Life Sci. 66: 265-270.
38. Ozardali I, Bitiren M, Karakilcik AZ, Zerin M, Aksoy N, Musa D. 2004. Effects of selenium on histopathological and enzymatic changes in experimental liver injury of rats. Exp. Toxicol. Pathol. 56: 59-64.
39. Rayman MP. 2000. The importance of selenium to human health. Lancet 356: 233-241.
40. Sasaki YF, Saga A, Akasaka M, Ishibashi S, Yoshida K, Su YQ, Matsusaka N, Tsuda S. 1998. Detection of in vivo genotoxicity of haloalkanes and haloalkenes carcinogenic to rodents by the alkaline single cell gel electrophoresis (comet) assay in multiple mouse organs. Mutat. Res. 419: 13-20.
41. Sébastien G, Fabrice N, ElMoukhtar A, Jean-Marie H, Daniel M. 2003. Assessment of genotoxic effect of benzo[a]pyrene in endotracheally treated rat using the comet assay. Mutat. Res. 534: 33-43.
42. Singh NP, McCoy MT, Tice RR, Schneider EL. 1988. A simple technique for quantitation of low levels of DNA damage in individual cells. Exp. Cell. Res. 175: 184-191.
43. Sivikova K, Piesova E, Dianovsky J. 2001. The protection of vitamin E and selenium against carbon tetrachloride-induced genotoxicity in ovine peripheral blood lymphocytes. Mutat. Res. 494: 135-142.
44. Wasser S, Lim GY, Ong CN, Tan CE. 2001. Antioxidant ebselen causes the resolution of experimentally induced hepatic fibrosis in rats. J. Gastroenterol. Hepatol. 16: 1244-1253.
45. Weber LW, Boll M, Stampfl A. 2003. Hepatotoxicity and mechanism of action of haloalkanes: carbon tetrachloride as a toxicological model. Crit. Rev. Toxicol. 33: 105-36.
46. Wernke MJ, Schell JD. 2004. Solvent and malignancy. Clin. Occup. Environ. Med. 4: 513-527.
47. 2 toxicity. Carcinogenesis 16: 1579-1584.
48. Zhang MG, Song G, Minuk GY. 1996. Effect of hepatic stimulator substance, herbal medicine, selenium/vitamin-E, and ciprofloxacin on cirrhosis in the rat. Gastroenterology 110: 1150-1155.