메뉴 건너뛰기




Volumn 534, Issue 1-2, 2003, Pages 33-43

Assessment of genotoxic effect of benzo[a]pyrene in endotracheally treated rat using the comet assay

Author keywords

Alkaline comet assay; Benzo a pyrene; DNA single strand breaks; Respiratory tract; Single cell gel electrophoresis

Indexed keywords

BENZO[A]PYRENE; SINGLE STRANDED DNA;

EID: 0037427886     PISSN: 13835718     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1383-5718(02)00252-8     Document Type: Article
Times cited : (43)

References (55)
  • 3
    • 0012122159 scopus 로고
    • International Agency for Research on Cancer (IARC) Monographs on the Evaluation of the Carcinogenic Risk of Chemicals to Humans, International Agency for Research on Cancer, Lyon
    • Overall evaluations of carcinogenicity: an updating of IARC Monographs vols. 1-42, International Agency for Research on Cancer (IARC) Monographs on the Evaluation of the Carcinogenic Risk of Chemicals to Humans, Suppl. 7, International Agency for Research on Cancer, Lyon, 1987.
    • (1987) Overall Evaluations of Carcinogenicity: An Updating of IARC Monographs vols. 1-42 , Issue.SUPPL. 7
  • 5
    • 0030297201 scopus 로고    scopus 로고
    • Chemical mixtures in atmospheric aerosols and their correlation to lung diseases and lung cancer occurrence in the general population
    • Spurny K.R. Chemical mixtures in atmospheric aerosols and their correlation to lung diseases and lung cancer occurrence in the general population. Toxicol. Lett. 88:1996;271-277.
    • (1996) Toxicol. Lett. , vol.88 , pp. 271-277
    • Spurny, K.R.1
  • 7
    • 0003294705 scopus 로고
    • World Health Organization (WHO): Polynuclear aromatic hydrocarbons (PAH)
    • World Health Organization, Regional Office for Europe, WHO Regional Publications, European Series No. 23, Copenhagen
    • World Health Organization (WHO): polynuclear aromatic hydrocarbons (PAH), in: Air quality Guidelines for Europe, World Health Organization, Regional Office for Europe, WHO Regional Publications, European Series No. 23, Copenhagen, 1987, pp. 105-117.
    • (1987) Air quality Guidelines for Europe , pp. 105-117
  • 8
    • 0025893062 scopus 로고
    • Benzo[a]pyrene: Environmental partitioning and human exposure
    • Hattemer-Frey H.A., Travis C.C. Benzo[a]pyrene: environmental partitioning and human exposure. Toxicol. Ind. Health. 7:1991;141-157.
    • (1991) Toxicol. Ind. Health , vol.7 , pp. 141-157
    • Hattemer-Frey, H.A.1    Travis, C.C.2
  • 9
    • 0029741259 scopus 로고    scopus 로고
    • In vitro induction of benzo[a]pyrene diol epoxide-DNA adducts in peripheral lymphocytes as a susceptibility marker for human lung cancer
    • Li D., Wang M., Cheng L., Spitz M.R., Hittelman W.N., Wei Q. In vitro induction of benzo[a]pyrene diol epoxide-DNA adducts in peripheral lymphocytes as a susceptibility marker for human lung cancer. Cancer Res. 56:1996;3638-3641.
    • (1996) Cancer Res. , vol.56 , pp. 3638-3641
    • Li, D.1    Wang, M.2    Cheng, L.3    Spitz, M.R.4    Hittelman, W.N.5    Wei, Q.6
  • 10
    • 0031910204 scopus 로고    scopus 로고
    • DNA adduct formation by polycyclic aromatic hydrocarbon dihydrodiol epoxides
    • Szeliga J., Dipple A. DNA adduct formation by polycyclic aromatic hydrocarbon dihydrodiol epoxides. Chem. Res. Toxicol. 11:1998;1-11.
    • (1998) Chem. Res. Toxicol. , vol.11 , pp. 1-11
    • Szeliga, J.1    Dipple, A.2
  • 11
    • 0342327333 scopus 로고    scopus 로고
    • The role of human glutathione transferases and epoxide hydrolases in the metabolism of xenobiotics
    • Seidegard J., Ekström G. The role of human glutathione transferases and epoxide hydrolases in the metabolism of xenobiotics. Environ. Health Perspect. 105:1997;791-796.
    • (1997) Environ. Health Perspect. , vol.105 , pp. 791-796
    • Seidegard, J.1    Ekström, G.2
  • 12
    • 0029956983 scopus 로고    scopus 로고
    • Glutathione S-transferase A1-1-catalysed conjugation of bay and fjord region diol epoxides of polycyclic aromatic hydrocarbons with glutathione
    • Jernström B., Funk M., Frank H., Mannervik B., Seidel A. Glutathione S-transferase A1-1-catalysed conjugation of bay and fjord region diol epoxides of polycyclic aromatic hydrocarbons with glutathione. Carcinogenesis. 17:1996;1491-1498.
    • (1996) Carcinogenesis , vol.17 , pp. 1491-1498
    • Jernström, B.1    Funk, M.2    Frank, H.3    Mannervik, B.4    Seidel, A.5
  • 13
    • 0022796435 scopus 로고
    • The enzymatic conjugation of glutathione with bay-region diol-epoxides of benzo[a]pyrene, benz[a]anthracene and chrysene
    • Robertson I.G.C., Jernström B. The enzymatic conjugation of glutathione with bay-region diol-epoxides of benzo[a]pyrene, benz[a]anthracene and chrysene. Carcinogenesis. 7:1986;1633-1636.
    • (1986) Carcinogenesis , vol.7 , pp. 1633-1636
    • Robertson, I.G.C.1    Jernström, B.2
  • 14
    • 0018571913 scopus 로고
    • In vivo covalent binding of organic chemicals to DNA as a quantitative indicator in the process of chemical carcinogenesis
    • Lutz W.K., Schlatter C. In vivo covalent binding of organic chemicals to DNA as a quantitative indicator in the process of chemical carcinogenesis. Mutat. Res. 65:1979;289-356.
    • (1979) Mutat. Res. , vol.65 , pp. 289-356
    • Lutz, W.K.1    Schlatter, C.2
  • 15
    • 0032832051 scopus 로고    scopus 로고
    • Cancer initiation by polycyclic aromatic hydrocarbons results from formation of stable DNA adducts rather than apurinic sites
    • Melendez-Colon V.J., Luch A., Seidel A., Baird W. Cancer initiation by polycyclic aromatic hydrocarbons results from formation of stable DNA adducts rather than apurinic sites. Carcinogenesis. 20:1999;1885-1891.
    • (1999) Carcinogenesis , vol.20 , pp. 1885-1891
    • Melendez-Colon, V.J.1    Luch, A.2    Seidel, A.3    Baird, W.4
  • 16
    • 0027761748 scopus 로고
    • Quantitative and temporal relationships between DNA adduct formation in target and surrogate tissues: Implications for biomonitoring
    • Nesnow S., Ross J., Nelson G., Holden K., Erexson G., Kligerman A., Gupta R.C. Quantitative and temporal relationships between DNA adduct formation in target and surrogate tissues: implications for biomonitoring. Environ. Health Perspect. 101:1993;37-42.
    • (1993) Environ. Health Perspect. , vol.101 , pp. 37-42
    • Nesnow, S.1    Ross, J.2    Nelson, G.3    Holden, K.4    Erexson, G.5    Kligerman, A.6    Gupta, R.C.7
  • 17
    • 0031586757 scopus 로고    scopus 로고
    • Oxidative stress to DNA, protein, and antioxidant enzymes (superoxide dismutase and catalase) in rats treated with benzo[a]pyrene
    • Kim K.B., Lee B.M. Oxidative stress to DNA, protein, and antioxidant enzymes (superoxide dismutase and catalase) in rats treated with benzo[a]pyrene. Cancer Lett. 113:1997;205-212.
    • (1997) Cancer Lett. , vol.113 , pp. 205-212
    • Kim, K.B.1    Lee, B.M.2
  • 19
    • 0027287314 scopus 로고
    • DNA repair in human lymphocytes treated in vitro with (+)-anti- and (+/-)-syn-benzo[a]pyrene diol epoxide
    • Celotti L., Ferraro P., Furlan D., Zanesi N., Pavanello S. DNA repair in human lymphocytes treated in vitro with (+)-anti- and (+/-)-syn-benzo[a]pyrene diol epoxide. Mutat. Res. 294:1993;117-126.
    • (1993) Mutat. Res. , vol.294 , pp. 117-126
    • Celotti, L.1    Ferraro, P.2    Furlan, D.3    Zanesi, N.4    Pavanello, S.5
  • 21
    • 0026522112 scopus 로고
    • The origins of DNA breaks: A consequence of DNA damage, DNA repair, or apoptosis?
    • Eastman A., Barry M.A. The origins of DNA breaks: a consequence of DNA damage, DNA repair, or apoptosis? Cancer Invest. 10:1992;229-240.
    • (1992) Cancer Invest. , vol.10 , pp. 229-240
    • Eastman, A.1    Barry, M.A.2
  • 22
    • 0021193203 scopus 로고
    • Microelectrophoretic study of radiation-induced DNA damages in individual mammalian cells
    • Östling O., Johanson K.J. Microelectrophoretic study of radiation-induced DNA damages in individual mammalian cells. Biochem. Biophys. Res. Commun. 123:1984;291-298.
    • (1984) Biochem. Biophys. Res. Commun. , vol.123 , pp. 291-298
    • Östling, O.1    Johanson, K.J.2
  • 23
    • 0023919963 scopus 로고
    • A simple technique for quantification of low levels of DNA damage in individual cells
    • Singh N.P., McCoy M.T., Tice R.R., Schneider E.L. A simple technique for quantification of low levels of DNA damage in individual cells. Exp. Cell Res. 175:1988;184-191.
    • (1988) Exp. Cell Res. , vol.175 , pp. 184-191
    • Singh, N.P.1    McCoy, M.T.2    Tice, R.R.3    Schneider, E.L.4
  • 24
    • 0025270234 scopus 로고
    • Heterogeneity in radiation-induced DNA damage and repair in tumor and normal cells measured using the comet assay
    • Olive P.L., Banath J.P., Durand R.E. Heterogeneity in radiation-induced DNA damage and repair in tumor and normal cells measured using the comet assay. Radiat. Res. 122:1990;86-94.
    • (1990) Radiat. Res. , vol.122 , pp. 86-94
    • Olive, P.L.1    Banath, J.P.2    Durand, R.E.3
  • 25
    • 0028956450 scopus 로고
    • The concepts of tail moment and tail inertia in the single cell gel electrophoresis assay
    • Hellman B., Vaghef H., Boström B. The concepts of tail moment and tail inertia in the single cell gel electrophoresis assay. Mutat. Res. 336:1995;123-131.
    • (1995) Mutat. Res. , vol.336 , pp. 123-131
    • Hellman, B.1    Vaghef, H.2    Boström, B.3
  • 26
    • 0033067120 scopus 로고    scopus 로고
    • Single cell gel electrophoresis assay: Methodology and applications
    • Rojas E., Lopez M.C., Valverde M. Single cell gel electrophoresis assay: methodology and applications. J. Chromatogr. 722:1999;225-254.
    • (1999) J. Chromatogr. , vol.722 , pp. 225-254
    • Rojas, E.1    Lopez, M.C.2    Valverde, M.3
  • 27
    • 0029933579 scopus 로고    scopus 로고
    • Evaluation of three methods for the detection of DNA single-strand breaks in human lymphocytes: Alkaline elution, nick translation, and single-cell gel electrophoresis
    • Leroy T. Evaluation of three methods for the detection of DNA single-strand breaks in human lymphocytes: alkaline elution, nick translation, and single-cell gel electrophoresis. J. Toxicol. Environ. Health. 47:1999;409-422.
    • (1999) J. Toxicol. Environ. Health , vol.47 , pp. 409-422
    • Leroy, T.1
  • 31
    • 0029102911 scopus 로고
    • The single cell gel electrophoresis/comet assay: A potential tool for detecting radiation-induced DNA damage in humans
    • Tice R.R., Strauss G.H. The single cell gel electrophoresis/comet assay: a potential tool for detecting radiation-induced DNA damage in humans. Stem Cells. 13:1995;207-214.
    • (1995) Stem Cells , vol.13 , pp. 207-214
    • Tice, R.R.1    Strauss, G.H.2
  • 33
    • 0026751636 scopus 로고
    • Assessment of radiation-induced DNA damage in human blood lymphocytes using the single-cell gel electrophoresis technique
    • Vijayalaxmi K.K., Tice R.R., Strauss G.H.S. Assessment of radiation-induced DNA damage in human blood lymphocytes using the single-cell gel electrophoresis technique. Mutat. Res. 271:1992;243-252.
    • (1992) Mutat. Res. , vol.271 , pp. 243-252
    • Vijayalaxmi, K.K.1    Tice, R.R.2    Strauss, G.H.S.3
  • 34
    • 0032851272 scopus 로고    scopus 로고
    • Preservation of comet assay slides: Comparison with fresh slides
    • Woods J.A., O'Leary K.A., McCarthy R.P., O'Brien N.M. Preservation of comet assay slides: comparison with fresh slides. Mutat. Res. 429:1999;181-187.
    • (1999) Mutat. Res. , vol.429 , pp. 181-187
    • Woods, J.A.1    O'Leary, K.A.2    McCarthy, R.P.3    O'Brien, N.M.4
  • 35
    • 0028910894 scopus 로고
    • The single cell gel electrophoresis assay for induced DNA damage (comet assay): Measurement of tail length and moment
    • Ashby J., Tinwell H., Lefevre P.A., Browne M.A. The single cell gel electrophoresis assay for induced DNA damage (comet assay): measurement of tail length and moment. Mutagenesis. 10:1995;85-90.
    • (1995) Mutagenesis , vol.10 , pp. 85-90
    • Ashby, J.1    Tinwell, H.2    Lefevre, P.A.3    Browne, M.A.4
  • 37
    • 0035163137 scopus 로고    scopus 로고
    • Complexities of the DNA base excision repair pathway for the repair of oxidative DNA damage
    • Mitra S., Boldogh I., Izumi T., Hazra T.K. Complexities of the DNA base excision repair pathway for the repair of oxidative DNA damage. Environ. Mol. Mutagen. 38:2001;180-190.
    • (2001) Environ. Mol. Mutagen. , vol.38 , pp. 180-190
    • Mitra, S.1    Boldogh, I.2    Izumi, T.3    Hazra, T.K.4
  • 38
    • 0032581406 scopus 로고    scopus 로고
    • Strain differences in cytochrome P4501A1 gene expression caused by 2,3,7,8-tetrachlorodibenzo-p-dioxin in the rat liver: Role of the aryl hydrocarbon receptor and its nuclear translocator
    • Jana N.R., Sarkar S., Yonemoto J., Tohyama C., Sone H. Strain differences in cytochrome P4501A1 gene expression caused by 2,3,7,8-tetrachlorodibenzo-p-dioxin in the rat liver: role of the aryl hydrocarbon receptor and its nuclear translocator. Biochem. Biophys. Res. Commun. 248:1998;554-558.
    • (1998) Biochem. Biophys. Res. Commun. , vol.248 , pp. 554-558
    • Jana, N.R.1    Sarkar, S.2    Yonemoto, J.3    Tohyama, C.4    Sone, H.5
  • 39
    • 0010417886 scopus 로고    scopus 로고
    • Responsiveness of the adult male rat reproductive tract to 2,3,7,8-tetrachlorodibenzo-p-dioxin exposure: Ah receptor and Arnt expression, CYP1A1 induction, and Ah receptor down-regulation
    • Roman B.L., Pollenz R.S., E Peterson R. Responsiveness of the adult male rat reproductive tract to 2,3,7,8-tetrachlorodibenzo-p-dioxin exposure: Ah receptor and Arnt expression, CYP1A1 induction, and Ah receptor down-regulation. Toxicol. Appl. Pharmacol. 150:1998;228-239.
    • (1998) Toxicol. Appl. Pharmacol. , vol.150 , pp. 228-239
    • Roman, B.L.1    Pollenz, R.S.2    E Peterson, R.3
  • 40
    • 0031557681 scopus 로고    scopus 로고
    • Differential time-course and dose-response relationships of TCDD-induced CYP1B1, CYP1A1, and CYP1A2, proteins in rats
    • Santostefano M.J., Ross D.G., Savas U., Jefcoate C.R., Birnbaum L.S. Differential time-course and dose-response relationships of TCDD-induced CYP1B1, CYP1A1, and CYP1A2, proteins in rats. Biochem. Biophys. Res. Commun. 233:1997;20-24.
    • (1997) Biochem. Biophys. Res. Commun. , vol.233 , pp. 20-24
    • Santostefano, M.J.1    Ross, D.G.2    Savas, U.3    Jefcoate, C.R.4    Birnbaum, L.S.5
  • 41
    • 0028012079 scopus 로고
    • Dioxin-responsive genes: Examination of dose-response relationships using quantitative reverse transcriptase-polymerase chain reaction
    • Vanden Heuvel J.P., Clark G.C., Kohn M.C., Tritscher A.M., Greenlee W.F., Lucier G.W., Bell D.A. Dioxin-responsive genes: examination of dose-response relationships using quantitative reverse transcriptase-polymerase chain reaction. Cancer Res. 54:1994;62-68.
    • (1994) Cancer Res. , vol.54 , pp. 62-68
    • Vanden Heuvel, J.P.1    Clark, G.C.2    Kohn, M.C.3    Tritscher, A.M.4    Greenlee, W.F.5    Lucier, G.W.6    Bell, D.A.7
  • 42
    • 0026356590 scopus 로고
    • Carcinogenesis studies with iron oxides
    • Steinhoff D., Mohr U., Hahnemann S. Carcinogenesis studies with iron oxides. Exp. Pathol. 43:1991;189-194.
    • (1991) Exp. Pathol. , vol.43 , pp. 189-194
    • Steinhoff, D.1    Mohr, U.2    Hahnemann, S.3
  • 43
    • 0028924814 scopus 로고
    • A critical appraisal of intratracheal instillation of benzo[a]pyrene to syrian golden hamsters as a model in respiratory tract carcinogenisis
    • Wolterbeek A.P., Schoevers E.J., Rutten A.A., Feron V.J. A critical appraisal of intratracheal instillation of benzo[a]pyrene to syrian golden hamsters as a model in respiratory tract carcinogenisis. Cancer Lett. 89:1995;107-116.
    • (1995) Cancer Lett. , vol.89 , pp. 107-116
    • Wolterbeek, A.P.1    Schoevers, E.J.2    Rutten, A.A.3    Feron, V.J.4
  • 46
    • 0021288060 scopus 로고
    • Metabolic activation and lung toxicity: A basis for cell-selective pulmonary damage by foreign chemicals
    • Boyd M.R. Metabolic activation and lung toxicity: a basis for cell-selective pulmonary damage by foreign chemicals. Environ. Health Perspect. 55:1984;47-51.
    • (1984) Environ. Health Perspect. , vol.55 , pp. 47-51
    • Boyd, M.R.1
  • 48
    • 0035876315 scopus 로고    scopus 로고
    • Cytochrome P450 1A1 (CYP1A1) in blood lymphocytes evidence for catalytic activity and mRNA expression
    • Dey A., Parmar D., Dayal M., Dhawan A., Seth P.K. Cytochrome P450 1A1 (CYP1A1) in blood lymphocytes evidence for catalytic activity and mRNA expression. Life Sci. 69:2001;383-393.
    • (2001) Life Sci. , vol.69 , pp. 383-393
    • Dey, A.1    Parmar, D.2    Dayal, M.3    Dhawan, A.4    Seth, P.K.5
  • 49
    • 0030051893 scopus 로고    scopus 로고
    • Demonstration of benzo[a]pyrene-induced DNA damage in mice by alkaline single cell gel electrophoresis: Evidence for strand breaks in liver but not in lymphocytes and bone marrow
    • Vaghef H., Wisen A.C., Hellman B. Demonstration of benzo[a]pyrene-induced DNA damage in mice by alkaline single cell gel electrophoresis: evidence for strand breaks in liver but not in lymphocytes and bone marrow. Pharmacol. Toxicol. 78:1996;37-43.
    • (1996) Pharmacol. Toxicol. , vol.78 , pp. 37-43
    • Vaghef, H.1    Wisen, A.C.2    Hellman, B.3
  • 51
    • 0030839678 scopus 로고    scopus 로고
    • Simple detection of chemicals mutagens by the alkaline single-cell gel electrophoresis (Comet) assay in multiple mouse organs (liver, lung, spleen, kidney, and bone marrow)
    • Sasaki Y.F., Nishidate E., Izumiyama F., Matsusaka N., Tsuda S. Simple detection of chemicals mutagens by the alkaline single-cell gel electrophoresis (Comet) assay in multiple mouse organs (liver, lung, spleen, kidney, and bone marrow). Mutat. Res. 391:1997;215-231.
    • (1997) Mutat. Res. , vol.391 , pp. 215-231
    • Sasaki, Y.F.1    Nishidate, E.2    Izumiyama, F.3    Matsusaka, N.4    Tsuda, S.5
  • 52
    • 1842301688 scopus 로고    scopus 로고
    • Comet assay in human biomonitoring studies: Reliability, validation, and applications
    • Collins A., Dusinska M., Franklin M., Somorovska M. Comet assay in human biomonitoring studies: reliability, validation, and applications. Environ. Mol. Mutagen. 30:1997;139-146.
    • (1997) Environ. Mol. Mutagen. , vol.30 , pp. 139-146
    • Collins, A.1    Dusinska, M.2    Franklin, M.3    Somorovska, M.4
  • 53
    • 0032705229 scopus 로고    scopus 로고
    • Biomonitoring of genotoxic risk in workers in a rubber factory: Comparison of the Comet Assay with cytogenetic methods and immunology
    • Somorovska M., Szabova E., Vodicka P., Tulinska J. Biomonitoring of genotoxic risk in workers in a rubber factory: comparison of the Comet Assay with cytogenetic methods and immunology. Mutat. Res. 445:1999;181-192.
    • (1999) Mutat. Res. , vol.445 , pp. 181-192
    • Somorovska, M.1    Szabova, E.2    Vodicka, P.3    Tulinska, J.4
  • 54
    • 0031015884 scopus 로고    scopus 로고
    • Alkaline single cell gel electrophoresis of DNA fragments in biomonitoring for genotoxicity: An introductory study on healthy human volunteers
    • Hellman B., Vaghef H., Friis L., Edling C. Alkaline single cell gel electrophoresis of DNA fragments in biomonitoring for genotoxicity: an introductory study on healthy human volunteers. Int. Arch. Occup. Environ. Health. 69:1997;185-192.
    • (1997) Int. Arch. Occup. Environ. Health , vol.69 , pp. 185-192
    • Hellman, B.1    Vaghef, H.2    Friis, L.3    Edling, C.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.