The basic helix-loop-helix transcription factor NeuroD1 facilitates interaction of Sp1 with the secretin gene enhancer

Molecular and Cellular Biology

Volumn 27, Issue 22, 2007, Pages 7839-7847

  Ray, Subir K ^a   Leiter, Andrew B ^a  

^a UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACID; BASIC HELIX LOOP HELIX TRANSCRIPTION FACTOR; DNA; DNA BINDING PROTEIN; HOMEODOMAIN PROTEIN; INSULIN; NEUROGENIC DIFFERENTIATION FACTOR; PROOPIOMELANOCORTIN; SECRETIN; TRANSCRIPTION FACTOR SP1; ZINC FINGER PROTEIN;

ARTICLE; BINDING SITE; CANCER CELL CULTURE; CARBOXY TERMINAL SEQUENCE; CELL LINEAGE; CONTROLLED STUDY; DIMERIZATION; DNA BINDING; DNA PROTEIN COMPLEX; ENHANCER REGION; FEMALE; GENE ACTIVATION; HELA CELL; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN EXPRESSION; PROTEIN PROTEIN INTERACTION; REGULATORY MECHANISM; TRANSCRIPTION REGULATION;

ANIMALS; BASE SEQUENCE; BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTORS; BINDING SITES; CELL LINE; ENHANCER ELEMENTS (GENETICS); GENE EXPRESSION REGULATION; HUMANS; MACROMOLECULAR SUBSTANCES; MICE; MOLECULAR SEQUENCE DATA; PROMOTER REGIONS (GENETICS); RATS; RECOMBINANT FUSION PROTEINS; SECRETIN; SEQUENCE ALIGNMENT; SP1 TRANSCRIPTION FACTOR; TCF TRANSCRIPTION FACTORS; TRANSCRIPTION, GENETIC;

MURINAE; MUS;

EID: 36049016094     PISSN: 02707306     EISSN: None     Source Type: Journal    
DOI: 10.1128/MCB.00438-07     Document Type: Article

References (35)

1. Biesiada, E., Y. Hamamori, L. Kedes, and V. Sartorelli. 1999. Myogenic basic helix-loop-helix proteins and Sp1 interact as components of a multiprotein transcriptional complex required for activity of the human cardiac α-actin promoter. Mol. Cell. Biol. 19:2577-2584.
2. Cong, Y.-S., J. Wen, and S. Bacchetti. 1999. The human telomerase catalytic subunit hTERT: organization of the gene and characterization of the promoter. Hum. Mol. Genet. 8:137-142.
3. Courey, A. J., and R. Tjian. 1988. Analysis of Sp1 in vivo reveals multiple transactivational domains, including a novel glutamine-rich activation motif. Cell 55:887-898.
4. Dumonteil, E., B. Laser, I. Constant, and J. Philippe. 1998. Differential regulation of the glucagon and insulin I gene promoters by basic helix-loop-helix transcription factors E47 and Beta2. J. Biol. Chem. 273:19945-19954.
5. Edlund, T., M. D. Walker, P. J. Barr, and W. J. Rutter. 1985. Cell-specific expression of the rat insulin gene: evidence for role of two distinct 5′ flanking elements. Science 230:912-916.
6. Gaudilliere, B., Y. Shi, and A. Bonni. 2002. RNA interference reveals a requirement for myocyte enhancer factor 2A in activity-dependent neuronal survival. J. Biol. Chem. 277:46442-46446.
7. German, M. S., M. A. Blanar, C. Nelson, L. G. Moss, and W. J. Rutter. 1991. Two related helix-loop-helix proteins participate in separate cell-specific complexes that bind the insulin enhancer. Mol. Endocrinol. 5:292-299.
8. Karlseder, J., H. Rothender, and E. Wintersberger. 1996. Interaction of Sp1 with the growth- and cell cycle-regulated transcription factor E2F. Mol. Cell. Biol. 16:1659-1667.
9. Kunkel, T. A. 1985. Rapid and efficient site-specific mutagenesis without phenotypic selection. Proc. Natl. Acad. Sci. USA 82:488-492.
10. Lai, J.-S., and W. Herr. 1992. Ethidium bromide provides a simple tool for identifying genuine DNA-independent protein associations. Proc. Natl. Acad. Sci. USA 89:6958-6962.
11. Lavrrar, J. L., and P. J. Farnham. 2004. The use of transient chromatin immunoprecipitation assays to test models for E2F1-specific transcriptional activation. J. Biol. Chem. 279:46343-46349.
12. Lee, J. E., S. M. Hollenberg, L. Snider, D. L. Turner, N. Lipnick, and H. Weintraub. 1995. Conversion of Xenopus ectoderm into neurons by neuroD, a basic helix-loop-helix protein. Science 268:836-844.
13. Lee, L. T., K. C. Tan-Un, R. T. Pang, D. T. Lam, and B. K. Chow. 2004. Regulation of the human secretin is controlled by the combined effects of CpG methylation, Sp1/Sp3 ratio, and the E-box element. Mol. Endocrinol. 18:1740-1755.
14. Lin, H., K. E. Yutzey, and S. F. Konieczny. 1991. Muscle-specific expression of the troponin I gene requires interactions between helix-loop-helix muscle regulatory factors and ubiquitous transcription factors. Mol. Cell. Biol. 11:267-280.
15. Liu, J., C. Lin, A. Gleiberman, K. A. Ohgi, T. Herman, H. P. Huang, M. J. Tsai, and M. G. Rosenfeld. 2001. Tbx19, a tissue-selective regulator of POMC gene expression. Proc. Natl. Acad. Sci. USA 98:8674-8679.
16. Liu, M., F. A. Pereira, S. D. Price, M. Chu, C. Shope, D. Himes, R. A. Eatock, W. E. Brownell, A. Lysakowski, and M. J. Tsai. 2000. Essential role of BETA2/NeuroD1 in development of the vestibular and auditory systems. Genes Dev. 14:2839-2854.
17. Liu, M., S. J. Pleasure, A. E. Collins, J. L. Noebels, F. J. Naya, M. J. Tsai, and D. H. Lowenstein. 2000. Loss of BETA2/NeuroD leads to malformation of the dentate gyrus and epilepsy. Proc. Natl. Acad. Sci. USA 97:865-870.
18. Lossi, L., L. Bottarelli, M. E. Candusso, A. B. Leiter, G. Rindi, and A. Merighi. 2004. Transient expression of secretin in serotoninergic neurons of mouse brain during development. Eur. J. Neurosci. 20:3259-3269.
19. Miyata, T., T. Maeda, and J. E. Lee. 1999. NeuroD is required for differentiation of the granule cells in the cerebellum and hippocampus. Genes Dev. 13:1647-1652.
20. Mutoh, H., B. Fung, F. Naya, M.-J. Tsai, J. Nishitani, and A. B. Leiter. 1997. The basic helix-loop-helix transcription factor BETA2/NeuroD is expressed in mammalian enteroendocrine cells and activates secretin gene expression. Proc. Natl. Acad. Sci. USA 94:3560-3564.
21. Mutoh, H., F. J. Naya, M.-J. Tsai, and A. B. Leiter. 1998. The basic helix loop helix protein BETA2 interacts with p300 to coordinate differentiation of secretin-expressing enteroendocrine cells. Genes Dev. 12:820-830.
22. Naya, F. J., H. Huang, Y. Qiu, H. Mutoh, F. DeMayo, A. B. Leiter, and M.-J. Tsai. 1997. Diabetes, defective pancreatic morphogenesis, and abnormal enteroendocrine differentiation in BETA2/NeuroD-deficient mice. Genes Dev. 11:2323-2334.
23. Naya, F. J., C. M. M. Stellrecht, and M.-J. Tsai. 1995. Tissue-specific regulation of the insulin gene by a novel basic helix-loop-helix transcription factor. Genes Dev. 9:1009-1019.
24. Ohneda, K., R. G. Mirmira, J. Wang, J. D. Johnson, and M. S. German. 2000. The homeodomain of PDX1 mediates multiple protein-protein interactions in the formation of a transcriptional activation complex on the insulin promoter. Mol. Cell. Biol. 20:900-911.
25. Poulin, G., M. Lebel, M. Chamberland, F. W. Paradis, and J. Drouin. 2000. Specific protein-protein interaction between basic helix-loop-helix transcription factors and homeoproteins of the Pitx family. Mol. Cell. Biol. 20:4826-4837.
26. Poulin, G., B. Turgeon, and J. Drouin. 1997. NeuroD1/β2 contributes to cell-specific transcription of the proopiomelanocortin gene. Mol. Cell. Biol. 17:6673-6682.
27. Ratineau, C., M. W. Petry, H. Mutoh, and A. B. Leiter. 2002. Cyclin D1 represses the basic helix-loop-helix transcription factor, BETA2/NeuroD. J. Biol. Chem. 277:8847-8853.
28. Ray, S. K., J. Nishitani, M. W. Petry, M. Y. Fessing, and A. B. Leiter. 2003. Novel transcriptional potentiation of BETA2/NeuroD on the secretin gene promoter by the DNA-binding protein Finb/RREB-1. Mol. Cell. Biol. 23: 259-271.
29. Rindi, G., S. G. N. Grant, Y. Yiangou, M. A. Ghatei, S. R. Bloom, V. L. Bautch, E. Solcia, and J. M. Polak. 1990. Development of neuroendocrine tumors in the gastrointestinal tract of transgenic mice. Am. J. Pathol. 136:1349-1363.
30. Sharma, S., U. S. Jhala, T. Johnson, K. Ferren, J. Leonard, and M. Montminy. 1997. Hormonal regulation of an islet-specific enhancer in the pancreatic homeobox gene STF-1. Mol. Cell. Biol. 17:2598-2604.
31. Shi, Y., J. Sawada, G. Sui, E. B. Affar, J. R. Whetstine, F. Lan, H. Ogawa, M. P. Luke, Y. Nakatani, and Y. Shi. 2003. Coordinated histone modifications mediated by a CtBP co-repressor complex. Nature 422:735-738.
32. Sui, G., C. Soohoo, E. B. Affar, F. Gay, Y. Shi, W. C. Forrester, and Y. Shi. 2002. A DNA vector-based RNAi technology to suppress gene expression in mammalian cells. Proc. Natl. Acad. Sci. USA 99:5515-5520.
33. Weinmann, A. S., S. M. Bartley, T. Zhang, M. Q. Zhang, and P. J. Farnham. 2001. Use of chromatin immunoprecipitation to clone novel E2F target promoters. Mol. Cell. Biol. 21:6820-6832.
34. Wheeler, M. B., J. Nishitani, A. M. J. Buchan, A. S. Kopin, W. Y. Chey, T. Chang, and A. B. Leiter. 1992. Identification of a transcriptional enhancer important for enteroendocrine and pancreatic islet cell-specific expression of the secretin gene. Mol. Cell. Biol. 12:3531-3539.
35. Wooten, L. G., and B. Ogretmen. 2005. Sp1/Sp3-dependent regulation of human telomerase reverse transcriptase promoter activity by the bioactive sphingolipid ceramide. J. Biol. Chem. 280:28867-28876.