An in vitro embryotoxicity assay based on the disturbance of the differentiation of murine embryonic stem cells into endothelial cells. I: Establishment of the differentiation protocol

Toxicology in Vitro

Volumn 21, Issue 8, 2007, Pages 1619-1630

  Festag, Matthias ^a   Sehner, Claudia ^a   Steinberg, Pablo ^b   Viertel, Bruno ^a  

^a BOEHRINGER INGELHEIM PHARMA GMBH AND CO KG   (Germany)

^b UNIVERSITY OF POTSDAM   (Germany)

Author keywords

bFGF; Differentiation; Embryoid body; Embryonic stem cells; Endothelial cells; Murine; PECAM 1; VE Cadherin; VEGF

Indexed keywords

ANGIOPOIETIN RECEPTOR; BASIC FIBROBLAST GROWTH FACTOR; CD31 ANTIGEN; ERYTHROPOIETIN; INTERLEUKIN 6; MESSENGER RNA; VASCULAR ENDOTHELIAL CADHERIN; VASCULOTROPIN; VASCULOTROPIN RECEPTOR 1; VASCULOTROPIN RECEPTOR 2;

ANIMAL CELL; ARTICLE; CELL DIFFERENTIATION; CONTROLLED STUDY; EMBRYONIC STEM CELL; EMBRYOTOXICITY; ENDOTHELIUM CELL; IN VITRO STUDY; MOUSE; NONHUMAN; PROTEIN EXPRESSION; RNA ANALYSIS;

ANIMALS; ANTIGENS, CD; ANTIGENS, CD31; CADHERINS; CELL CULTURE TECHNIQUES; CELL DIFFERENTIATION; CULTURE MEDIA; EMBRYONIC STEM CELLS; ENDOTHELIAL CELLS; GENE EXPRESSION REGULATION; MICE; RECEPTOR, TIE-2; TOXICITY TESTS; VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR-1; VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR-2;

MURINAE;

EID: 36049005950     PISSN: 08872333     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tiv.2007.06.018     Document Type: Article

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