Maturation of embryonic stem cells into endothelial cells in an in vitro model of vasculogenesis

Blood

Volumn 93, Issue 4, 1999, Pages 1253-1263

  Hirashima, Masanori ^a   Kataoka, Hiroshi ^a   Nishikawa, Satomi ^a   Matsuyoshi, Norihisa ^a   Nishikawa, Shin ichi ^a  

^a KYOTO UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

CADHERIN; CD31 ANTIGEN; CD34 ANTIGEN; CHIMERIC PROTEIN;

ANGIOGENESIS; ANIMAL CELL; ARTICLE; CELL ADHESION; CELL CULTURE; CELL DENSITY; CELL JUNCTION; CELL MATURATION; CELL MIGRATION; CELL PROLIFERATION; CONTROLLED STUDY; ENDOTHELIUM CELL; MOLECULAR DYNAMICS; MOUSE; NONHUMAN; PRIORITY JOURNAL; STEM CELL;

EID: 0033557571     PISSN: 00064971     EISSN: None     Source Type: Journal    
DOI: 10.1182/blood.v93.4.1253     Document Type: Article

References (54)

1. Coffin JD, Poole TJ: Embryonic vascular development: immunohistochemical identification of the origin and subsequent morphogenesis of the major vessel primordia in quail embryos. Development 102:735, 1988
2. Poole TJ, Coffin JD: Vasculogenesis and angiogenesis: Two distinct morphogenetic mechanisms establish embryonic vascular pattern. J Exp Zool 251:224, 1989
3. Risau W, Sariola H, Zerwes HG, Sasse J, Ekblom P, Kemler R, Doetschman T: Vasculogenesis and angiogenesis in embryonic-stem-cell-derived embryoid bodies. Development 102:471, 1988
4. Folkman J: Angiogenesis - Retrospect and outlook. EXS 61:4, 1992
5. Hudlicka O, Brown M. Egginton S: Angiogenesis in skeletal and cardiac muscle. Physiol Rev 72:369, 1992
6. Folkman J: Angiogenesis in cancer, vascular, rheumatoid and other disease. Nat Med 1:27, 1995
7. His W: Lecithoblast und Angioblast der Wirbelthiere. Abhandl KS Ges Wiss Math Phys 22:171, 1900
8. Ferrara N, Henkel WJ: Pituitary follicular cells secrete a novel heparin-binding growth factor specific for vascular endothelial cells Biochem Biophys Res Commun 161:851, 1989
9. Leung DW, Cachianes G, Kuang WJ, Goeddel DV, Ferrara N: Vascular endothelial growth factor is a secreted angiogenic mitogen. Science 246:1306, 1989
10. Keck PJ, Hauser SD, Krivi G, Sanzo K, Warren T, Feder J, Connolly DT: Vascular permeability factor, an endothelial cell mitogen related to PDGF. Science 246:1309, 1989
11. Matthews W, Jordan CT, Gavin M, Jenkins NA, Copeland NG, Lemischka IR: A receptor tyrosine kinase cDNA isolated from a population of enriched primitive hematopoietic cells and exhibiting close genetic linkage to c-kit. Proc Natl Acad Sci USA 88:9026, 1991
12. Shibuya M, Yamaguchi S, Yamane A, Ikeda T, Tojo A, Matsushime H, Sato M: Nucleotide sequence and expression of a novel human receptor-type tyrosine kinase gene (flt) closely related to the fms family. Oncogene 5:519, 1990
13. Lampugnani MG, Resnati M, Raiteri M, Pigott R, Pisacane A. Houen G, Ruco LP, Dejana E: A novel endothelial-specific membrane protein is a marker of cell-cell contacts. J Cell Biol 118:1511, 1992
14. Breier G, Breviario F, Caveda L, Berthier R, Schnurch H, Gotsch U, Vestweber D, Risau W, Dejana E: Molecular cloning and expression of murine vascular endothelial-cadherin in early stage development of cardiovascular system. Blood 87:630, 1996
15. Carrneliet P, Ferreira V, Breier G, Pollefeyt S, Kieckens L, Gertsenstein M, Fahrig M, Vandenhoeck A, Harpal K, Eberhardt C, Declercq C, Pawling J, Moons L, Collen D, Risau W, Nagy A: Abnormal blood vessel development and lethality in embryos lacking a single VEGF allele. Nature 380:435, 1996
16. Ferrara N, Carver Moore K, Chen H, Dowd M, Lu L, O'Shea KS, Powell Braxton L, Hillan KJ, Moore MW: Heterozygous embryonic lethality induced by targeted inactivation of the VEGF gene. Nature 380:439, 1996
17. Shalaby F, Rossant J, Yamaguchi TP, Gertsenstein M, Wu XF, Breitman ML, Schuh AC: Failure of blood-island formation and vasculogenesis in Flk-1-deficient mice. Nature 376:62, 1995
18. Fong GH, Rossant J, Gensenstein M, Breitman ML: Role of the Flt-1 receptor tyrosine kinase in regulating the assembly of vascular endothelium. Nature 376:66, 1995
19. Vittet D, Buchou T, Schweitzer A, Dejana E, Huber P: Targeted null-mutation in the vascular endothelial-cadherin gene impairs the organization of vascular-like structures in embryoid bodies. Proc Natl Acad Sci USA 94:6273, 1997
20. Risau W: Mechanisms of angiogenesis. Nature 386:671, 1997
21. Hanahan D: Signaling vascular morphogenesis and maintenance. Science 277:48, 1997
22. Doetschman TC, Eistetter H, Katz M, Schmidt W, Kemler R: The in vitro development of blastocyst-derived embryonic stem cell lines: formation of visceral yolk sac, blood islands and myocardium. J Embryol Exp Morphol 87:27, 1985
23. Wang R, Clark R, Bautch VL: Embryonic stem cell-derived cystic embryoid bodies form vascular channels: An in vitro model of blood vessel development. Development 114:303, 1992
24. Krah K, Mironov V, Risau W, Flamme I: Induction of vasculogenesis in quail blastodisc-derived embryoid bodies. Dev Biol 164:123, 1994
25. Flamme I, Risau W: Induction of vasculogenesis and hematopoiesis in vitro. Development 116:435, 1992
26. Palis J, McGrath KE, Kingsley PD. Initiation of hematopoiesis and vasculogenesis in murine yolk sac explants. Blood 86:156, 1995
27. Shirayoshi Y, Nose A, Iwasaki K, Takeichi M: N-linked oligosaccharides are not involved in the function of a cell-cell binding glycoprotein E-cadherin. Cell Struct Funct 11:245, 1986
28. Kataoka H, Takakura N, Nishikawa S, Tsuchida K, Kodama H, Kunisada T, Risau W, Kita T, Nishikawa SI: Expressions of PDGF receptor alpha, c-Kit and Flk1 genes clustering in mouse chromosome 5 define distinct subsets of nascent mesodermal cells. Dev Growth Differ 39:729, 1997
29. Matsuyoshi N, Toda K, Horiguchi Y, Tanaka T, Nakagawa S, Takeichi M, Imamura S: In vivo evidence of the critical role of cadherin-5 in murine vascular integrity. Proc Assoc Am Physicians 109:362, 1997
30. Robertson E, Bradley A, Kuehn M, Evans M: Germ-line transmission of genes introduced into cultured pluripotential cells by retroviral vector Nature 323:445, 1986
31. + cells at a diverging point of endothelial and hemopoietic lineages. Development 125:1747, 1998
32. Kodama H, Nose M, Yamaguchi Y, Tsunoda J, Suda T, Nishikawa S, Nishikawa SI: In vitro proliferation of primitive hemopoietic stem cells supported by stromal cells: Evidence for the presence of a mechanism(s) other than that involving c-kit receptor and its ligand. J Exp Med 176:351, 1992
33. Kodama H, Nose M, Niida S, Nishikawa S, Nishikawa SI: Involvement of the c-kit receptor in the adhesion of hematopoietic stem cells to stromal cells. Exp Hematol 22:979, 1994
34. Maddon PJ, Littman DR, Godfrey M, Maddon DE, Chess L, Axel R: The isolation and nucleotide sequence of a cDNA encoding the T cell surface protein T4: A new member of the immunoglobulin gene family. Cell 42:93, 1985
35. Takakura N, Yoshida H, Kunisada T, Nishikawa S, Nishikawa SI: Involvement of platelet-derived growth factor receptor-alpha in hair canal formation. J Invest Dermatol 107:770, 1996
36. Newman PJ, Berndt MC, Gorski J, White GCd, Lyman S, Paddock C, Muller WA: PECAM-1(CD31) cloning and relation to adhesion molecules of the immunoglobulin gene superfamily. Science 247:1219, 1990
37. Simmons DL, Walker C, Power C, Pigott R: Molecular cloning of CD31, a putative intercellular adhesion molecule closely related to carcinoembryonic antigen. J Exp Med 171:2147, 1990
38. Brown J, Greaves MF, Molgaard HV: The gene encoding the stem cell antigen, CD34, is conserved in mouse and expressed in haemopoietic progenitor cell lines, brain, and embryonic fibroblasts. Int Immunol 3:175, 1991
39. Baumhueter S, Dybdal N, Kyle C, Lasky LA: Global vascular expression of murine CD34, a sialomucin-like endothelial ligand for L-selectin. Blood 84:2554, 1994
40. Voyta JC, Via DP, Butterfield CE, Zetter BR: Identification and isolation of endothelial cells based on their increased uptake of acetylated-low density lipoprotein. J Cell Biol 99:2034, 1984
41. Aiello LP, Pierce EA, Foley ED, Takagi H, Chen H, Riddle L, Ferrara N, King GL, Smith LE: Suppression of retinal neovascularization in vivo by inhibition of vascular endothelial growth factor (VEGF) using soluble VEGF-receptor chimeric proteins. Proc Natl Acad Sci USA 92:10457, 1995
42. Maglione D, Guerriero V, Viglietto G, Delli Bovi P, Persico MG: Isolation of a human placenta cDNA coding for a protein related to the vascular permeability factor. Proc Natl Acad Sci USA 88:9267, 1991
43. Park JE, Chen HH, Winer J, Houck KA, Ferrara N: Placenta growth factor. Potentiation of vascular endothelial growth factor bioactivity, in vitro and in vivo, and high affinity binding to Fit-1 but not to Flk-1/KDR. J Biol Chem 269:25646, 1994
44. de Vries C, Escobedo JA, Ueno H, Houck K, Ferrara N, Williams LT: The fms-like tyrosine kinase, a receptor for vascular endothelial growth factor. Science 255:989, 1992
45. Millauer B, Wizigmann Voos S, Schnurch H, Martinez R, Moller NP, Risau W, Ullrich A: High affinity VEGF binding and developmental expression suggest FIk-1 as a major regulator of vasculogenesis and angiogenesis. Cell 72:835, 1993
46. Quinn TP, Peters KG, De Vries C, Ferrara N, Williams LT: Fetal liver kinase 1 is a receptor for vascular endothelial growth factor and is selectively expressed in vascular endothelium. Proc Natl Acad Sci USA 90:7533, 1993
47. Clauss M, Weich H, Breier G, Knies U, Rockl W, Waltenberger J, Risau W: The vascular endothelial growth factor receptor Fit-1 mediates biological activities. Implications for a functional role of placenta growth factor in monocyte activation and chemotaxis. J Biol Chem 271:17629, 1996
48. Risau W, Flamme I: Vasculogenesis. Annu Rev Cell Dev Biol 11:73, 1995
49. Yamaguchi TP, Dumont DJ, Conlon RA, Breitman ML, Rossant J: flk-1, an flt-related receptor tyrosine kinase is an early marker for endothelial cell precursors. Development 118:489, 1993
50. Dumont DJ, Fong GH, Pun MC, Gradwohl G, Alitalo K, Breitman ML: Vascularization of the mouse embryo: A study of flk-1, tek, tie, and vascular endothelial growth factor expression during development. Dev Dyn 203:80, 1995
51. Vittet D, Prandini MH, Berthier R, Schweitzer A, Martin Sisteron H, Uzan G, Dejana E: Embryonic stem cells differentiate in vitro to endothelial cells through successive maturation steps. Blood 88:3424, 1996
52. Flamme I, von Reutern M, Drexler HC, Syed Ali S, Risau W: Overexpression of vascular endothelial growth factor in the avian embryo induces hypervascularization and increased vascular permeability without alterations of embryonic pattern formation. Dev Biol 171:399, 1995
53. Drake CJ, Little CD: Exogenous vascular endothelial growth factor induces malformed and hyperfused vessels during embryonic neovascularization. Proc Natl Acad Sci USA92:7657, 1995
54. Hiratsuka S, Minowa O, Kuno J, Noda T, Shibuya M: Flt-1 lacking the tyrosine kinase domain is sufficient for normal development and angiogenesis in mice. Proc Natl Acad Sci USA 95:9349, 1998