Mechanisms of neutrophil death in human immunodeficiency virus-infected patients: Role of reactive oxygen species, caspases and map kinase pathways

Clinical and Experimental Immunology

Volumn 150, Issue 3, 2007, Pages 539-545

  Salmen, S ^a   Montes, H ^a   Soyano, A ^b   Hernandez D ^c   Berrueta, L ^a  

^a UNIVERSIDAD DE LOS ANDES   (Venezuela)

^b INSTITUTO VENEZOLANO DE INVESTIGACIONES CIENTÍFICAS   (Venezuela)

^c Hospital Vargas de Caracas   (Venezuela)

Author keywords

Caspases; Cell death; HIV; Neutrophils; ROS

Indexed keywords

CASPASE; CASPASE 3; CASPASE 8; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE P38; REACTIVE OXYGEN METABOLITE;

ADOLESCENT; ADULT; APOPTOSIS; ARTICLE; CELL SURVIVAL; CLINICAL ARTICLE; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME ANALYSIS; ENZYME INHIBITION; FEMALE; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS INFECTED PATIENT; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; HYDROLYSIS; MALE; NEUTROPHIL; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN FUNCTION;

ADOLESCENT; ADULT; APOPTOSIS; CASPASE 3; CASPASES; CELL SURVIVAL; CELLS, CULTURED; FEMALE; HIV INFECTIONS; HUMANS; MALE; MIDDLE AGED; NEUTROPHILS; OXIDATIVE STRESS; P38 MITOGEN-ACTIVATED PROTEIN KINASES; REACTIVE OXYGEN SPECIES; SIGNAL TRANSDUCTION; SUPEROXIDES;

EID: 36048962716     PISSN: 00099104     EISSN: 13652249     Source Type: Journal    
DOI: 10.1111/j.1365-2249.2007.03524.x     Document Type: Article

References (42)

1. Leist M, Jaattela M. Four deaths and a funeral: from caspases to alternative mechanisms. Nat Rev Mol Cell Biol 2001 8 : 589 98.
2. Akgul C, Moulding DA, Edwards SW. Molecular control of neutrophil apoptosis. FEBS Lett 2001 487 : 318 22.
3. Edwards SW, Derouet M, Howse M, Moots RJ. Regulation of neutrophil apoptosis by Mcl-1. Biochem Soc Trans 2004 32 : 489 92.
4. Keel M, Ungethum U, Steckholzer U et al. Interleukin-10 counterregulates proinflammatory cytokine-induced inhibition of neutrophil apoptosis during severe sepsis. Blood 1997 90 : 3356 63.
5. Klein JB, Rane MJ, Scherzer JA et al. Granulocyte-macrophage colony-stimulating factor delays neutrophil constitutive apoptosis through phosphoinositide 3-kinase and extracellular signal-regulated kinase pathways. J Immunol 2000 164 : 4286 91.
6. Scheel-Toellner D, Wang K, Craddock R et al. Reactive oxygen species limit neutrophil life span by activating death receptor signaling. Blood 2004 104 : 2557 64.
7. Kuritzkes DR. Neutropenia, neutrophil dysfunction, and bacterial infection in patients with human immunodeficiency virus disease: the role of granulocyte colony-stimulating factor. Clin Infect Dis 2000 30 : 256 60.
8. Pitrak DL, Tsai HC, Mullane MK, Sutton SH, Stevens P. Accelerated neutrophil apoptosis in the acquired immunodeficiency syndrome. J Clin Invest 1996 98 : 2714 9.
9. Salmen S, Teran G, Borges L et al. Increased Fas-mediated apoptosis in polymorphonuclear cells from HIV-infected patients. Clin Exp Immunol 2004 137 : 166 72.
10. Akgul C, Edwards SW. Regulation of neutrophil apoptosis via death receptors. Cell Mol Life Sci 2003 60 : 2402 8.
11. DR Alessi Cuenda A Cohen P Dudley DT Saltiel AR. PD 098059 is a specific inhibitor of the activation of mitogen-activated protein kinase kinase in vitro and in vivo. J Biol Chem 1995 270 : 27489 94.
12. Cuenda AJ, Rouse J, Doza YN et al. SB203580 is a specific inhibitor of a MAP kinase homologue which is stimulated by cellular stresses and interleukin-1. FEBS Lett 1995 364 : 229 33.
13. Scheel-Toellner D, Wang KQ, Webb PR et al. Early events in spontaneous neutrophil apoptosis. Biochem Soc Trans 2004 32 : 461 4.
14. Cai J, Jones DP. Mitochondrial redox signaling during apoptosis. J Bioenerg Biomembr 1999 31 : 327 34.
15. Chen Q, Crosby M, Almasan A. Redox regulation of apoptosis before and after cytochrome C release. Korean J Biol Sci 2003 7 : 1 9.
16. Simon HU, Haj-Yehia A, Levi-Schaffer F. Role of reactive oxygen species (ROS) in apoptosis induction. Apoptosis 2000 5 : 415 8.
17. Bras M, Queenan B, Susin SA. Programmed cell death via mitochondria: different modes of dying. Biochemistry (Mosc) 2005 70 : 231 9.
18. Cimino F, Esposito F, Ammendola R, Russo T. Gene regulation by reactive oxygen species. Curr Top Cell Regul 1997 35 : 123 48.
19. Lee MW, Park SC, Yang YG et al. The involvement of reactive oxygen species (ROS) and p38 mitogen-activated protein (MAP) kinase in TRAIL/Apo2L-induced apoptosis. FEBS Lett 2002 512 : 313 8.
20. Mansat-de Mas V, Bezombes C, Quillet-Mary A et al. Implication of radical oxygen species in ceramide generation, c-Jun N-terminal kinase activation and apoptosis induced by daunorubicin. Mol Pharmacol 1999 56 : 867 74.
21. Seo SR, Chong SA, Lee SI et al. Zn2+-induced ERK activation mediated by reactive oxygen species causes cell death in differentiated PC12 cells. J Neurochem 2001 78 : 600 10.
22. Zhang X, Shan P, Sasidhar M et al. Reactive oxygen species and extracellular signal-regulated kinase 1/2 mitogen-activated protein kinase mediate hyperoxia-induced cell death in lung epithelium. Am J Respir Cell Mol Biol 2003 28 : 305 15.
23. Philchenkov A. Caspases: potential targets for regulating cell death. J Cell Mol Med 2004 8 : 432 44.
24. Woodman RC, Newburger PE, Anklesaria P et al. A new X-linked variant of chronic granulomatous disease characterized by the existence of a normal clone of respiratory burst-competent phagocytic cells. Blood 1995 85 : 231 41.
25. Alvarado-Kristensson M, Pörn-Ares MI, Grethe S, Smith D, Zheng L, Andersson T. p38 Mitogen-activated protein kinase and phosphatidylinositol 3-kinase activities have opposite effects on human neutrophil apoptosis. FASEB J 2001 16 : 129 31.
26. Zhang S, Lin ZN, Yang CF, Shi X, Ong CN, Shen HM. Suppressed NF-kappaB and sustained JNK activation contribute to the sensitization effect of parthenolide to TNF-alpha-induced apoptosis in human cancer cells. Carcinogenesis 2004 25 : 2191 9.
27. Arroyo A, Modriansky M, Serinkan FB et al. NADPH oxidase-dependent oxidationand externalization of phosphatidylserine during apoptosis in Me2SO-differentiated HL-60 cells: role in phagocytic clearence. J Biol Chem 2002 277 : 49965 75.
28. Zhang B, Hirahashi J, Cullere X, Mayadas TN. Elucidation of molecular events leading to neutrophil apoptosis following phagocytosis cross-talk between caspase 8, reactive oxygen species, and MAPK/ERK activation. J Biol Chem 2003 278 : 28443 54.
29. Elbim C, Prevot MH, Bouscarat F et al. Polymorphonuclear neutrophils from human immunodeficiency virus-infected patients show enhanced activation, diminished fMLP-induced 1-selectin shedding, and an impaired oxidative burst after cytokine priming. Blood 1994 84 : 2759 66.
30. Munoz JF, Salmen S, Berrueta LR et al. Effect of human immunodeficiency virus type 1 on intracellular activation and superoxide production by neutrophils. J Infect Dis 1999 180 : 206 10.
31. Waterman WH, Molski TF, Huang CK, Adams JL, Sha'afi RI. Tumour necrosis factor-alpha-induced phosphorylation and activation of cytosolic phospholipase A2 are abrogated by an inhibitor of the p38 mitogen-activated protein kinase cascade in human neutrophils. Biochem J 1996 319 : 17 20.
32. Israel N, Gougerot-Pocidalo MA. Oxidative stress in human immunodeficiency virus infection. Cell Mol Life Sci 1997 53 : 864 70.
33. Pugliese A, Vidotto V, Beltramo T, Torre D. Phagocytic activity in human immunodeficiency virus type 1 infection. Clin Diagn Lab Immunol 2005 12 : 889 95.
34. Fecho K, Cohen PL. Fas ligand (gld)- and Fas (lpr)-deficient mice do not show alterations in the extravasation or apoptosis of inflammatory neutrophils. J Leukoc Biol 1998 64 : 373 83.
35. Elbim C, Pillet S, Prevost MH et al. The role of phagocytes in HIV-related oxidative stress. J Clin Virol 2001 20 : 99 109.
36. Sacktor N, Haughey N, Cutler R et al. Novel markers of oxidative stress in actively progressive HIV dementia. J Neuroimmunol 2004 157 : 176 84.
37. Buttke TM, Sandstrom PA. Oxidative stress as a mediator of apoptosis. Immunol Today 1994 15 : 7 10.
38. Alvarez-Maqueda M, El Bekay R, Monteseirin J et al. Homocysteine enhances superoxide anion release and NADPH oxidase assembly by human neutrophils. Effects on MAPK activation and neutrophil migration. Atherosclerosis 2004 172 : 229 38.
39. Gardai S, Whitlock BB, Helgason C et al. Activation of SHIP by NADPH oxidase-stimulated Lyn leads to enhanced apoptosis in neutrophils. J Biol Chem 2002 277 : 5236 46.
40. Alvarado-Kristensson M, Melander F, Leandersson K, Ronnstrand L, Wernstedt C, Andersson T. p38-MAPK signals survival by phosphorylation of caspase-8 and caspase-3 in human neutrophils. J Exp Med 2004 199 : 449 58.
41. Popik W, Pitha PM. Early activation of mitogen-activated protein kinase kinase, extracellular signal-regulated kinase, p38 mitogen-activated protein kinase, and c-Jun N-terminal kinase in response to binding of simian immunodeficiency virus to Jurkat T cells expressing CCR5 receptor. Virology 1998 252 : 210 7.
42. Singh IN, El-Hage N, Campbell ME et al. Differential involvement of p38 and JNK MAP kinases in HIV-1 Tat and gp120-induced apoptosis and neurite degeneration in striatal neurons. Neuroscience 2005 135 : 781 90.