Molecular modeling, synthesis, and screening of new bacterial quorum-sensing antagonists

Journal of Microbiology and Biotechnology

Volumn 17, Issue 10, 2007, Pages 1598-1606

  Kim, Cheoljin ^a   Kim, Jaeeun ^a   Park, Hyung Yeon ^b   Mclean, Robert J C ^c   Kim, Chan Kyung ^b   Jeon, Jongho ^a   Yi, Song Se ^a   Kim, Young Gyu ^a   Lee, Yoon Sik ^a   Yoon, Jeyong ^a  

^a Seoul National University   (South Korea)

^b Inha University   (South Korea)

^c TEXAS STATE UNIVERSITY   (United States)

Author keywords

Binding energies; FlexX docking; N (sulfanyl ethanoyl) L HSLs; Quorum sensing antagonists

Indexed keywords

2,2 DIMETHYLBUTANOYL HOMOSERINE LACTONE; ANTIINFECTIVE AGENT; N (ALKYLSULFANYLETHANOYL) LEVO HOMOSERINE LACTONE DERIVATIVE; N (FLUOROALKANOYL) LEVO HOMOSERINE LACTONE DERIVATIVE; N (FLUOROSULFONYL) LEVO HOMOSERINE LACTONE DERIVATIVE; N ACYLHOMOSERINE LACTONE; UNCLASSIFIED DRUG;

ANTIBACTERIAL ACTIVITY; ARTICLE; BINDING SITE; COMPUTER PROGRAM; CONTROLLED STUDY; DRUG EFFICACY; DRUG RECEPTOR BINDING; DRUG SCREENING; DRUG STRUCTURE; DRUG SYNTHESIS; INFRARED SPECTROSCOPY; MASS SPECTROMETRY; MOLECULAR MODEL; NONHUMAN; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; QUORUM SENSING; RHIZOBIUM RADIOBACTER; SOLID PHASE SYNTHESIS;

4-BUTYROLACTONE; ANTI-BACTERIAL AGENTS; BIOFILMS; BIOLOGICAL ASSAY; DRUG DESIGN; MODELS, MOLECULAR; PSEUDOMONAS AERUGINOSA; QUORUM SENSING; RHIZOBIUM; SMALL MOLECULE LIBRARIES; STRUCTURE-ACTIVITY RELATIONSHIP;

AGROBACTERIUM TUMEFACIENS; BACTERIA (MICROORGANISMS);

EID: 36048949935     PISSN: 10177825     EISSN: 17388872     Source Type: Journal    
DOI: None     Document Type: Article

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