Estrogenically regulated LRP16 interacts with estrogen receptor α and enhances the receptor's transcriptional activity

Endocrine-Related Cancer

Volumn 14, Issue 3, 2007, Pages 741-753

  Han, W D ^a   Zhao, Y L ^a   Meng, Y G ^a   Zang, L ^a   Wu, Z Q ^a   Li, Q ^a   Si, Y L ^a   Huang, K ^a   Ba, J M ^a   Morinaga, H ^b   Nomura, M ^b   Mu, Y M ^a  

^a CHINESE PLA GENERAL HOSPITAL   (China)

^b KYUSHU UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

CYCLIN D1; ESTROGEN; ESTROGEN RECEPTOR ALPHA; GLUTATHIONE TRANSFERASE; LEUKEMIA RELATED PROTEIN 16; MYC PROTEIN; PROTEIN; SMALL INTERFERING RNA; UNCLASSIFIED DRUG;

ARTICLE; CELL GROWTH; CELL LINE; CELL PROLIFERATION; CELL STRAIN MCF 7; CONTROLLED STUDY; EPITHELIUM; ESTROGEN ACTIVITY; FEEDBACK SYSTEM; GENE TARGETING; GROWTH INHIBITION; HUMAN; HUMAN CELL; IMMUNOPRECIPITATION; ONCOGENE C MYC; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN INTERACTION; PROTEIN LOCALIZATION; SIGNAL TRANSDUCTION; TRANSCRIPTION INITIATION; TUMOR CELL; UPREGULATION;

BREAST NEOPLASMS; CELL PROLIFERATION; ESTROGEN RECEPTOR ALPHA; ESTROGENS; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; NEOPLASM PROTEINS; PROTEIN BINDING; PROTEIN STRUCTURE, TERTIARY; TRANS-ACTIVATION (GENETICS); TRANS-ACTIVATORS; TRANSFECTION; TUMOR CELLS, CULTURED; UP-REGULATION;

EID: 35948993495     PISSN: 13510088     EISSN: None     Source Type: Journal    
DOI: 10.1677/ERC-06-0082     Document Type: Article

References (55)

1. Allred DC, Mohsin SK & Fuqua SA 2001 Histological and biological evolution of human premalignant breast disease. Endocrine-Related Cancer 8 47-61.
2. Augereau P, Miralles F, Cavailles V, Gaudelet C, Parker M & Rochefort H 1994 Characterization of the proximal estrogen-responsive element of human cathepsin D gene. Molecular Endocrinology 8 693-703.
3. Beato M, Herrlich P & Schutz G 1995 Steroid hormone receptors: many actors in search of a plot. Cell 83 851-857.
4. Carrol JS, Swarbrick A, Musgrove EA & Sutherland RL 2002 Mechanisms of growth arrest by c-Myc antisense oligonucleotides in MCF-7 breast cancer cells: implication for the antiproliferative effects. Cancer Research 62 3126-3131.
5. Danielian PS, White R, Lees JA & Parker MG 1992 Identification of a conserved region required for hormone dependent transcriptional activation by steroid hormone receptors. EMBO Journal 11 1025-1033.
6. Deroo BJ & Korach KS 2006 Estrogen receptor and human disease. Journal of Clinical Investigation 116 561-570.
7. Dobrzycka KM, Townson SM, Jiang S & Oesterreich S 2003 Estrogen receptor corepressors-a role in human breast cancer? Endocrine-Related Cancer 10 517-536.
8. Endoh H, Maruyama K, Masuhiro Y, Kobayashi Y, Goto M, Tai H, Yanagisawa J, Metzger D, Hashimoto S & Kato S 1999 Purification and identification of p68 RNA helicase acting as a transcriptional coactivator specific for the activation function 1 of human estrogen receptor α. Molecular and Cellular Biology 19 5363-5372.
9. Finkel T, Duc J, Fearon ER, Dang CV & Tomaselli GF 1993 Detection and modulation in vivo of helix-loop-helix proteinprotein interactions. Journal of Biological Chemistry 268 5-8.
10. Foster JS & Wimalasena J 1996 Estrogen regulates activity of cyclin-dependent kinases and retinoblastoma protein phosphorylation in breast cancer cells. Endocrinology 10 488-498.
11. Fujita T, Kobayashi Y, Wada O, Tateishi Y, Kitada L, Yamamoto Y, Takashima H, Murayama A, Yano T, Baba T et al. 2003 Full activation of estrogen receptor α activation function-1 induces proliferation of breast cancer cells. Journal of Biological Chemistry 278 26704-26714.
12. Fujita N, Kajita M, Taysavang P & Wade PA 2004 Hormonal regulation of metastasis-associated protein 3 transcription in breast cancer cells. Molecular Endocrinology 18 2937-2949.
13. Glass CK & Rosenfeld MG 2000 The coregulator exchange in transcriptional functions of nuclear receptors. Genes and Development 14 121-141.
14. Hall JM & McDonnell DP 2005 Coregulators in nuclear estrogen receptor action: from concept to therapeutic targeting. Molecular Interventions 5 343-357.
15. Hall JM, Couse JF & Korach KS 2001 The multifaceted mechanisms of estradiol and estrogen receptor signaling. Journal of Biological Chemistry 276 36869-36872.
16. Han WD, Yu L, Lou FD, Wang QS, Zhao Y, Shi ZJ, Jiao HY & Zhou JJ 2001 Cloning and expression characteristics of the full length cDNA for a novel leukemia-associated gene LRP16. Academic Journal of PLA Postgraduate Medical School 17 209-214.
17. Han WD, Mu YM, Lu XC, Xu ZM, Li XJ, Yu L, Song HJ, Li M, Lu JM, Zhao YL et al. 2003 Up-regulation of LRP16 mRNA by 17β-estrodial through activation of estrogen α (ERα), but not ERβ, and promotion of human breast cancer MCF-7 cell proliferation: a preliminary report. Endocrine-Related Cancer 10 217-224.
18. Hong CY, Suh JH, Kim K, Gong EY, Jeon SH, Ko M, Seong RH, Kwon HB & Lee K 2005 Modulation of androgen receptor transactivation by the SWI3-related gene product (SRG3) in multiple ways. Molecular and Cellular Biology 12 4841-4852.
19. Horwitz KB, Jackson TA, Bain DL, Richer JK, Takimoto GS & Tung L 1996 Nuclear receptor coactivators and corepressors. Molecular Endocrinology 10 1167-1177.
20. Jeltsch JM, Roberts M, Schatz C, Garnier JM, Brown AM & Chambon P 1987 Structure of the human oestrogen-responsive gene pS2. Nucleic Acids Research 15 1401-1414.
21. Klinge CM 2000 Estrogen receptor interaction with co-activators and co-repressors. Steroid 65 227-251.
22. Lauritsen KJ, List HJ, Reiter R, Wellstein A & Riegel AT 2002 A role for TGF-beta in estrogen and retinoid mediated regulation of the nuclear receptor coactivator AIB1 in MCF-7 breast cancer cells. Oncogene 21 7147-7155.
23. Lees JA, Fawell SE & Parker MG 1989 Identification of two transactivation domains in the mouse oestrogen receptor. Nucleic Acids Research 17 5477-5488.
24. Liao DX, Han WD, Zhao YL, Pu YD, Mu YM, Luo CH & Li XH 2006 The expression and clinical significance of LRP16 gene in human breast cancer. Ai Zheng 25 866-870.
25. Mangelsdorf DJ, Thummel C, Beato M, Herrlich P, Schutz G, Umesono K, Blumberg B, Mark M, Chambon P & Evans RM 1998 The nuclear receptor superfamily: the second decade. Cell 83 835-839.
26. Masood S 1992 Estrogen and progesterone receptors in cytology: a comprehensive review. Diagnostic Cytopathology 8 475-491.
27. McDonnell DP & Norris JD 2002 Connections and regulation of the human estrogen receptor. Science 296 1642-1644.
28. McKenna NJ & O'Malley BW 2002 Combinatorial control of gene expression by nuclear receptors and coregulators. Cell 108 465-474.
29. McKenna NJ, Lanz RB & O'Malley BW 1999 Nuclear receptor coregulators: cellular and molecular biology. Endocrine-Reviews 20 321-344.
30. Métivier R, Penot G, Flouriot G & Pakdel F 2001 Synergism between ERα transactivation function 1 (AF-1) and AF-2 mediated by steroid receptor coactivator protein-1: requirement for the AF-1 α-helical core and for a direct interaction between the N- and C-terminal domains. Molecular Endocrinology 15 1953-1970.
31. Métivier R, Penot G, Húbner MR, Reid G, Brand H, Koš M & Gannon F 2003 Estrogen receptor α directs ordered, cyclical, and combinatorial recruitment of cofactors on a natural target promoter. Cell 11 751-763.
32. Misiti S, Schomburg L, Yen PM & Chin WW 1998 Expression and hormonal regulation of cofactor and corepressor genes. Endocrinology 139 2493-2500.
33. Nilsson S, Makela S, Treuter E, Tujague M, Thomsen J, Andersson G, Enmark E, Pettersson K, Warner M & Gustafsson JA 2001 Mechanisms of estrogen action. Physiological Reviews 81 1535-1565.
34. Norris JD, Fan D, Stallcup MR & McDonnell DP 1998 Enhancement of estrogen receptor transcriptional activity by the coactivator GRIP-1 hightlights the role of activation function 2 in determining estrogen receptor pharmacology. Journal of Biological Chemistry 273 6679-6688.
35. Planas-Silva MD & Weinberg RA 1997 Estrogen-dependent cyclin E-cdk2 activation through p21 redistribution. Molecular and Cellular Biology 17 4059-4069.
36. 1-S phase progression ia accompanied by increased cyclin D1 expression and decreased cyclin-dependent kinase inhibitor association with cyclin E-Cdk2. Journal of Biological Chemistry 272 10882-10894.
37. Prall OW, Rogan EM & Sutherland RL 1998a Estrogen regulation of cell cycle progression in breast cancer cells. Journal of Steroid Biochemistry and Molecular Biology 65 169-174.
38. Prall OW, Rogan EM, Musgrove EA, Watts CK & Sutherland RL 1998b c-Myc or Cyclin D1 mimics estrogen effects on Cyclin E-Cdk2 activation and cell cycle reentry. Molecular and Cellular Biology 18 4499-4508.
39. Sabbah M, Courilleau D, Mester J & Redeuilh G 1999 Estrogen induction of the cyclin D1 promoter: involvement of a cAMP response-like element. PNAS 96 11217-11222.
40. Safe S 2001 Transcriptional activation of genes by 17β-estradiol through estrogen receptor-Sp1 interactions. Vitamins and Hormones-Advances in Research and Applications 62 231-252.
41. Shang Y, Hu X, DiRenzo J, Lazar MA & Brown M 2000 Cofactor dynamics and sufficiency in estrogen receptor-regulated transcription. Cell 103 843-852.
42. Shao WL & Brown M 2004 Advances in estrogen receptor biology: prospects for improvements in targeted breast cancer therapy. Breast Cancer Research 6 39-52.
43. Shi Y, Downes M, Xie W, Kao HY, Ordentlich P, Tsai CC, Hon M & Evans RM 2001 Sharp, an inducible cofactor that integrates nuclear receptor repression and activation. Genes and Development 15 1140-1151.
44. Si YL, Han WD, Zhao YL, Mu YM, Li Q & Wu ZQ 2006 5′-proximal GC-rich region of LRP16 genes determines its expression regulation by estrogen receptor α through Sp1 mediation. Academic Journal of PLA Postgraduate Medical School 27 161-165.
45. Sun G, Porter W & Safe S 1998 Estrogen-induced retinoic acid receptor α 1 gene expression: role of estrogen receptor-Sp1 complex. Molecular Endocrinology 12 882-890.
46. Thenot S, Charpin M, Bonnet S & Cavailles V 1999 Estrogen receptor cofactors expression in breast and endometrial human cancer cells. Molecular and Cellular Endocrinology 156 85-93.
47. Vastro-Rivera E, Samudio I & Safe S 2001 Estrogen regulation of cyclin D1 gene expression in ZR-75 breast cancer cells involves multiple enhancer elements. Journal of Biological Chemistry 275 30853-30861.
48. Vienonen A, Miettinen S, Manninen T, Altucci L, Wilhelm E & Ylikomi T 2003 Regulation of nuclear receptor and cofactor expression in breast cancer cell lines. European Journal of Endocrinology 148 469-479.
49. Watanabe T, Inoue S, Hiroi H, Orimo A, Kawashima H & Muramatsu M 1998 Isolation of estrogen-responsive genes with a GpC island library. Molecular and Cellular Biology 18 442-449.
50. Watanabe M, Yanagisawa J, Kitagawa H, Takeyama K, Ogawa S, Arao Y, Suzawa M, Kobayashi Y, Yano T, Yoshikawa H et al. 2001 A subfamily of RNA-binding DEAD-box proteins acts as an estrogen receptor α coactivator through the N-terminal activation domain (AF-1) with an RNA coactivator, SRA. EMBO Journal 206 1341-1352.
51. Weisz A & Bresciani F 1988 Estrogen induces expression of c-fos and c-myc protooncogenes in rat uterus. Molecular Endocrinology 2 816-824.
52. Weisz A & Rosales R 1990 Identification of an estrogen response element upstream of the human c-fos gene that binds the estrogen receptor and the AP-1 transcription factor. Nucleic Acids Research 18 5097-6106.
53. Yu JY, DeRuiter SL & Turner DL 2002 RNA interference by expression of short-interfering RNAs and hairpin RNAs in mammalian cells. PNAS 99 6047-6052.
54. Zhao YL, Han WD, Li Q, Mu YM, Lu XC, Yu L, Song HJ, Li X, Lu JM & Pan CY 2005 Mechanism of transcriptional regulation of LRP16 gene expression by 17-β estradiol in MCF-7 human breast cancer cells. Journal of Molecular Endocrinology 34 77-89.
55. Zwijsen RM, Wientjens E, Klompmaker R, van der Sman J, Bernards R & Michalides RJ 1997 CDK-independent activation of estrogen receptor by cyclin D1. Cell 88 405-415.